Clinical trials: Acute Pain, completed
Low Back Pain, Acute
Interfascial Infiltration for Acute Unspecific Low Back Pain in the Emergency Department
Pain relief and functional impairment have been shown to remain poor to moderate over weeks after emergency department discharge, in patients who seek ED management for acute nontraumatic, nonradicular low back pain.
- Trial name
- PreSosLumbago (NCT03968185)
- Testing
- Interfascial infiltration, Standard medical treatment
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Training, Exercise
Hypoalgesic Effects of Exercise and Training of Different Modalities
Further research is needed to explore the analgesic effects of post-acute and chronic exercise and if effects are partially dependent on lower H-reflex/V-wave inhibition by group III and IV muscle afferents desensitization.
- Conditions
- Training, Exercise, Fatigue, Occlusion
- Trial name
- NCT07105410
- Testing
- Aim #1: The effect of post-exercise circulatory occlusion on H-reflex and V-wave, Aim #2: The hypoalgesic effects of acute exercise of different modalities, Aim #3: The hypoalgesic effects of chronic training of different modalities
- Where
- Portugal
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Pain, Postoperative
Association of Preoperative Pain With Moderate to Severe Acute Pain After Laparoscopic Cholecystectomy.
Despite advancement in perioperative pain management, more than half of the patients still report moderate-severe pain after surgery.
- Trial name
- NCT05543668
- Where
- Nepal
- Volunteers
- 195 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Acute Coronary Syndrome, Acute Chest Pain
Better Evaluation of Acute Chest Pain With Computed Tomography Angiography
The purpose of this study is to determine whether cardiac CT can improve triage of acute chest pain patients in the emergency department.
- Trial name
- BEACON (NCT01413282)
- Testing
- Cardiac CT
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Erasmus Medical Center
Postoperative Pain
Efficacy Study of Ketamine for Postoperative Pain in Opioid Dependent Patients
Patients who are dependent on opioids often have poor pain relief after major surgery. This study tests the hypothesis that adding intravenous ketamine to a postoperative regimen of intravenous opioids for postoperative pain will…
- Trial name
- NCT01591382
- Testing
- Ketamine, Hydromorphone PCA
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Brigham and Women's Hospital
Hallux Valgus
A Study of Tapentadol Immediate-Release in the Treatment of Patients With Acute Pain From Bunionectomy
The purpose of this study is to demonstrate the efficacy of at least 1 dose of tapentadol IR 50 mg and/or 75 mg versus placebo using the sum of pain intensity difference at 48 hours (SPID48) to measure analgesic effect in Korean…
- Trial name
- NCT01516008
- Testing
- Tapentadol IR 50 mg, Tapentadol IR 75 mg
- Where
- 7 sites in South Korea
- Volunteers
- 353 people
- Sponsor
- Janssen Research & Development, LLC
Acute Pain, Anxiety
The 50:50 Nitrous Oxide vs 2% Lidocaine Challenge
The main goal of the project is to assess pain levels and patient comfort during the administration of a 50:50 Nitrous Oxide/Oxygen gas mixture, in comparison to the same parameters under the standard method used at our…
- Conditions
- Acute Pain, Anxiety, Central Venous Catheter
- Trial name
- NCT07618676
- Testing
- Nitrous Oxide-Oxygen, Lidocaine 2% Injectable Solution
- Where
- Serbia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Institute for Oncology and Radiology of Serbia
Lower Back Pain, Lower Back Pain Chronic
Effects of a Lower Back Wrap Device on Lower Back Pain, Physical Function, and Quality of Life
The goal of this counterbalanced cross-over study is to determine whether a recovery lumbar wrap effectively reduces lower back pain and improves outcomes related to physical function and quality of life in adults with LBP in…
- Conditions
- Lower Back Pain, Lower Back Pain Chronic, Acute Low Back Pain
- Trial name
- NCT06749912
- Testing
- Low back pain wrap
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- State University of New York at Buffalo
Acute Chest Syndrome
ST Elevation in Acute Chest Pain; Could Measurement of Lipoprotein-associated Phospholipase A2 (Lp-PLA2) be Helpful to the Clinician?
A blood test (2-3 cc peripheral venous blood) drawn /used from already available required lab tests to distinguish between pericarditis accompanied with electrocardiogram (ECG) signs mimicking infarction.
- Trial name
- NCT01041339
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexhander Izhaki
Pain, Acute
Brain and Genetic Predictors of Individual Differences in Pain and Analgesia
The purpose of the study is to gain a better understanding of pain processing in the brain. Our understanding of how pain is processed in the brain is limited.
- Trial name
- PAINGEN (NCT03781570)
- Testing
- Control Cream
- Where
- United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Pain, Acute, Dissociation
Low Dose Ketamine Infusion for Analgesia in the Emergency Department to Reduce Side Effects
This will be an intent to treat prospective, double blind, double-dummy, randomized trial. Our primary objective is the reduction of side effects of sub dissociative dose ketamine given by slow intravenous (IV) infusion over 30…
- Trial name
- NCT05518877
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Summa Health System
Liver Transplantation
Reducing Pain With Methadone and Ketamine in Liver Transplant
The goal of this clinical trial is to learn if using methadone and ketamine during an adult deceased donor liver transplant can help decrease pain after surgery.
- Trial name
- RELIEF-LT (NCT06868589)
- Testing
- Methadone, ketamine, Hydromorphone
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Lahey Clinic
Pain, Anxiety
Decreasing REcurrent Pain and Anxiety in Medical Procedures With a Pediatric Population: a Pilot Study
Children with injuries, including burns, experience severe pain intensity during medical procedures despite the increasing doses of analgesics.
- Conditions
- Pain, Anxiety, Burns, Child
- Trial name
- DREAM-P (NCT02977923)
- Testing
- VR distraction via Oculus Rift, Standard pharmacological treatment
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- St. Justine's Hospital
Age ≥18 Years, Presigned Consentement to Participate in the Study
Use of ACUPUNCTURE in Emergency Departement
Pain is the most common reason that patients present to an emergency department (ED) and is often inadequately managed. Evidence suggests that acupuncture is effective for pain relief, yet it is rarely practiced in the ED.
- Trial name
- NCT01622959
- Testing
- Acupuncture
- Where
- Tunisia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Lung Cancer
Acute and Chronic Pain After Video-assisted Thoracoscopic Surgery for Lung Cancer
The aim of this study is to evaluate whether preoperative CT- guided hookwire localization would influence the incidence and intensity of acute and chronic pain after VATS.
- Trial name
- NCT05478460
- Testing
- Hookwire localization
- Where
- China
- Volunteers
- 161 people
- Sponsor
- Fudan University
Pain and Hysteroscopy
Virtual Reality Effects on Pain During Hysteroscopy Hysteroscopy: A Randomized Control Trial
The Objective of this study is to compare pain levels in women undergoing office-based hysteroscopies using Virtual Reality versus control in a randomized control prospective trial.
- Trial name
- VR (NCT04802460)
- Testing
- Virtual reality headset (The Guided Meditation VR App through Oculus Go headset)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Post Operative Pain, Acute, Renal Transplant Donor of Left Kidney
Effectiveness of Thread Embedding Acupuncture Analgesia at the EX-B2 Point Combined With Standard Therapy After Laparoscopic Living Donor Nephrectomy
Kidney transplantation is the main option besides hemodialysis and continuous ambulatory peritoneal dialysis (CAPD) to prolong and improve the quality of life for patients with end-stage renal disease.
- Conditions
- Post Operative Pain, Acute, Renal Transplant Donor of Left Kidney, Quality of Life, Acupuncture Analgesia
- Trial name
- NCT06197620
- Testing
- Thread embedding acupuncture and standard therapy
- Where
- Indonesia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Abdominal Pain, Acute Pain
Diagnostic Performance of Low-Dose CT for Acute Abdominal Conditions
The goal of this non-inferiority observational study is to assess the diagnostic performance of low-dose CT with deep learning image reconstruction (DLIR) in adult participants with acute abdominal conditions.
- Conditions
- Abdominal Pain, Acute Pain, Acute Cholecystitis, Acute Appendicitis
- Trial name
- DETECT_Acute (NCT05651360)
- Testing
- low-dose CT
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 246 people
- Sponsor
- Oslo University Hospital
Pain
Neural Correlates of Acute Pain Dynamics
This work aims to study the neural correlates and determinants of pain dynamics related to changes in a noxious stimulus.
- Trial name
- NCT05669924
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Regional Anesthesia Morbidity, Pain, Acute
Understanding Rebound Pain After Regional Anesthesia Resolution in Healthy Volunteers
Regional anesthesia decreases postoperative pain scores and opioid consumption, and may prevent chronic pain after surgery in patients undergoing surgery.
- Conditions
- Regional Anesthesia Morbidity, Pain, Acute, Healthy
- Trial name
- NCT06005480
- Testing
- Mepivacaine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
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