Clinical trials: Acute Pancreatitis
Pancreatitis, Pancreatitis, Acute
Intermittent Fasting for Pancreatitis
The purpose of this research is to compare intermittent fasting with a standard diet approach for improving the quality of life related to your pancreas disease.
- Conditions
- Pancreatitis, Pancreatitis, Acute, Pancreatitis, Chronic, Pancreas Disease
- Trial name
- IFPanc (NCT04760847)
- Testing
- Intermittent Fasting, No intermittent fasting
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Idiopathic Acute Pancreatitis
Preventing Recurrent 'Idiopathic' Acute Pancreatitis Through Laparoscopic Cholecystectomy (PICUS-2)
Rationale: Annually, acute pancreatitis is diagnosed in 6,500 patients in the Netherlands. In up to 25% of patients no definitive cause can be determined after routine work-up including endoscopic ultrasound and this is deemed to…
- Trial name
- PICUS-2 (NCT06391359)
- Testing
- Laparoscopic cholecystectomy, Watchful waiting
- Where
- Netherlands
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- M.G. Besselink
Post-ERCP Acute Pancreatitis
Short-term Intravenous Fluids for Prevention of Post-ERCP Pancreatitis
This study will explore the efficacies of several practical short-term (peri-procedural) intravenous fluid regimens in the prevention of post- endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP).
- Trial name
- STRIPE (NCT06260878)
- Testing
- Intravenous Ringer's lactate
- Where
- Canada
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Acute Pancreatitis Drug-Induced
Markers in Acute Pancreatitis-1
Prospective, multi-national, multi-centre observational diagnostic study of novel microRNA and protein biomarkers in peripheral blood and/or urine to detect and predict the severity of drug-associated acute pancreatitis (AP)…
- Trial name
- MAP-1 (NCT05279079)
- Testing
- Assessment of accuracy of microRNA and pancreatic enzyme markers in blood and/or urine in the detection and/or prediction of severity of drug-associated acute pancreatitis
- Where
- 4 sites in Germany, Spain and 1 more
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Chronic Pancreatitis, Acute Recurrent Pancreatitis
Incorporating Endoscopic Ultrasound and Elastography Towards Improving Outcomes of Pediatric Pancreatitis Management
The main reason for this research study is to find out more about acute recurrent pancreatitis and chronic pancreatitis in children.
- Trial name
- NCT06068426
- Testing
- Transabdominal ultrasound Shear wave elastography
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- David Vitale MD
Acute Pancreatic Necrosis, Acute Pancreatitis (AP)
Serum TAM Receptor Tyrosine Kinase Ligands in Acute Pancreatitis
AXL and MERTK are homologous members of the TAM (TYRO3, AXL, MERTK) receptor tyrosine kinase family. They function as critical regulators of antiviral immunity, autoimmune responses, and tumor microenvironment modulation through…
- Trial name
- NCT07023055
- Where
- China
- Volunteers
- 896 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Chronic Pancreatitis, Chronic Pain
Pancreatic Quantitative Sensory Testing (P-QST)
Quantitative Sensory Testing (QST) is a novel investigative technique used in other pain conditions to evaluate patterns of chronic pain, and in this study will be used to elucidate pain patterns in patients with Chronic…
- Conditions
- Chronic Pancreatitis, Chronic Pain, Acute Recurrent Pancreatitis
- Trial name
- NCT06996535
- Testing
- Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pancreatitis, Acute
Acute Pancreatitis Targets (APT) Study
The severity of acute pancreatitis varies considerably from minor symptoms to multi-organ failure. The pathophysiological mechanisms associated with these individual differences in severity are largely unknown.
- Trial name
- APT (NCT04570852)
- Testing
- LiDCO
- Where
- Denmark
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Hvidovre
Acute Pancreatitis
Exploring the Mechanism of Severe Acute Pancreatitis Based on Metagenomics, Metabolomics and Proteomics
The goal of this observational study is to learn about the biomarkers and mechanisms of severe acute pancreatitis in 30 healthy controls, 30 patients of mild acute pancreatitis, 30 patients of moderately severe acute…
- Trial name
- NCT06230432
- Where
- China
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Nanchang University
Pancreas Necrosis
Imaging Modalities for Pancreatic Collections
The purpose of this project is to provide appropriate administrative and technical supports for the warehousing and use of imaging data in pancreatic necrosis data for research purposes.
- Trial name
- NCT03556501
- Testing
- Endoscopy
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Acute Pancreatitis, 2019 Novel Coronavirus Infection
Study and Analysis of Acute Pancreatitis Complicated With COVID-19
The goal of this observational study was to explore the complex relationship between changes in the intestinal microbiome and serum metabolites in patients with novel coronavirus infection and acute pancreatitis.
- Trial name
- NCT05722678
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yuansong Sun
Necrotizing Pancreatitis
Molecular Analysis of Microbial DNA in Infected Necrotizing Pancreatitis
Necrotizing pancreatitis is a severe form of inflammation of the pancreas with subsequent destruction of the pancreas (necrosis).
- Trial name
- NCT01815489
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Pancreatitis, Acute
Lactated Ringer's Versus Normal Saline for Acute Pancreatitis
Acute pancreatitis is a common problem in the United States necessitating 275,000 hospital admissions per year, with resultant healthcare costs of approximately 2.5 billion USD annually.
- Trial name
- NCT03642769
- Testing
- Fluid administration
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Acute Pancreatitis
Ketorolac in Acute Pancreatitis
This study will compare pain management strategies for patients hospitalized with acute pancreatitis. Standard of care pain management will be compared to standard of care plus intravenous ketorolac.
- Trial name
- NCT04282200
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Pancreatitis, Acute Necrotizing
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Investigation of GSK3335065 Intravenous (IV) Infusion in Healthy Adults
GSK3335065 is being developed as a treatment for acute pancreatitis with the intent of reducing 3-hydroxykynurenine (3HK) levels to the normal range (or lower) and maintaining them at this level throughout the treatment period.
- Trial name
- NCT03245619
- Testing
- GSK3335065
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Acute Pancreatitis, Microbial Colonization
Microbiota in Acute Pancreatitis: Prospective Multicenter Study
The objective of the study is to classify and carry out a quantitative analysis of the different bacterial species present in the intestinal microbiota of patients with acute pancreatitis and determine if there are significant…
- Trial name
- NCT04038554
- Testing
- Feces and saliva analysis
- Where
- 2 sites in Spain
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Corporacion Parc Tauli
Severe Acute Pancreatitis
Relationship Between Acute Severe Pancreatitis and Mitochondrial DNA
Plasma mtDNA analysis aids in predicting pancreatic necrosis in severe acute pancreatitis patients.After the onset of severe acute pancreatitis, pancreatic necrosis and the content of mtDNA in plasma will increase, showing a…
- Trial name
- NCT04079777
- Testing
- Clinical treatment
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Chenzhou
Acute Pancreatitis
Assessment of the Different Etiological and Susceptibility Markers in Patients With Pancreatitis: Investigating IG4, Cytomegalovirus, Coxsackie- Virus, Genetic Polymorphism of Vitamin D Receptor Gene
Acute pancreatitis (AP) is a multifactorial disease. AP represents a significant number of hospital admissions. Most of the patients are admitted in an acute setting.
- Trial name
- NCT03830073
- Testing
- Measurement of VDR genetic polymorphism
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acute Biliary Pancreatitis
Acute Biliary Pancreatitis - Optimal Time for Cholecystectomy
In patients with mild gallstone pancreatitis, early cholecystectomy within 48 hours might reduce the risk of recurrent gallstone-related complications, compared with the more commonly used strategy in our locality of conservative…
- Trial name
- NCT03085407
- Testing
- early cholecystectomy, delayed cholecystectomy
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- South Valley University