Clinical trials: Acute Respiratory Distress Syndrome (ARDS)
COVID-19, Respiratory Distress Syndrome
Comparison of Two Respiratory Physiotherapy Treatments in Postcovid-19 Patients.
To test the effectiveness of a respiratory physiotherapy treatment plan in patients who have passed COVID-19, comparing two randomized groups, for the performance of different respiratory musculature training protocols.
- Trial name
- NCT05435443
- Testing
- PowerBreathe and PEP Therosold tools
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Universidad Católica de Ávila
Preterm Birth Complication, Neonatal Morbidity and Mortality
Delayed Versus Immediate Cord Clamping in Preterm Birth
The goal of this study is to evaluate whether delayed cord clamping improves early neonatal outcomes compared with immediate clamping in preterm birth.
- Conditions
- Preterm Birth Complication, Neonatal Morbidity and Mortality, Cord Clamping, Delayed Cord Clamping
- Trial name
- PREM-CORD (NCT07699666)
- Testing
- Delayed Umbilical Cord Clamping, Immediate Umbilical Cord Clamping
- Where
- Tunisia
- Volunteers
- 200 people
- Sponsor
- Faculty of Medicine of Tunis
Acute Respiratory Distress Syndrome
Factors Associated With the Use of Lung Protective Ventilation Strategy (LPV) in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients in Intensive Care Unit (ICU)
In 1967, Ashbaugh et al first described 12 patients with a syndrome characterized by the acute onset dyspnea, severe hypoxemia, diffuse lung infiltrates on the chest radiography and decreased lung compliance.
- Trial name
- NCT01102322
- Testing
- Quality
- Where
- Taiwan
- Volunteers
- 111 people
- Sponsor
- National Taiwan University Hospital
Respiratory Distress Syndrome (Neonatal), Respiratory Distress of Newborn
How Different Levels of CPAP Affect Oxygen Delivery and Lung Expansion in Preterm Infants
With this study, it is expected to learn more about preterm babies on breathing support with nasal continuous positive airway pressure (nCPAP).
- Trial name
- NCT07674953
- Testing
- Effective oxygen delivery and lung expansion measurement
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Arkansas
Critical Illness, Heart Failure
Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress
Serious acute heart and lung illnesses like heart failure, severe COVID, and sepsis often leave survivors struggling not only physically, but also with lasting depression, anxiety, and stress.
- Conditions
- Critical Illness, Heart Failure, Sepsis, Ards
- Trial name
- Lift 3 (NCT07634419)
- Testing
- Lift mobile mindfulness, Enlighten Recovery education program
- Where
- 3 sites in United States
- Volunteers
- 450 people
- Sponsor
- Duke University
Acute Lung Injury, Adult Respiratory Distress Syndrome
Clinical Trial of Nebulized Hypertonic Saline to Attenuate Post-Traumatic Acute Lung Injury
This study evaluates the use of nebulized hypertonic saline (aerosolized salt water) as a preventive treatment for post-traumatic acute lung injury (ALI).
- Trial name
- NCT01667666
- Testing
- Nebulized hypertonic saline
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Denver Health and Hospital Authority
Respiratory Distress Syndrome, Surfactant Administration by Aerosolization
Does The Surfactant Administration by Aerosolization Effective?
The present study was designed to evaluate, in premature babies with RDS breathing spontaneously, the efficacy of combined treatment with nasal continuous positive airway pressure (CPAP) and aerosolized surfactant.
- Trial name
- NCT02825953
- Testing
- surfactant, nasal continuous positive airway pressure, non-invasive intermittent positive-pressure ventilation
- Volunteers
- 75 people
- Sponsor
- nihat demir
Sepsis, Acute Lung Injury
Effects of TNX-832 (Sunol cH36) in Subjects With Acute Lung Injury/Acute Respiratory Distress Syndrome
This Phase I/IIa, multi-center, randomized, placebo-controlled, single-blinded dose-escalation study evaluated TNX-832 (also referred to as ALT-836 and Sunol cH36) in subjects with suspected or proven bacteria-induced ALI/ARDS.
- Conditions
- Sepsis, Acute Lung Injury, Acute Respiratory Distress Syndrome
- Trial name
- NCT01438853
- Testing
- TNX-832
- Where
- 7 sites in United States, Canada
- Volunteers
- 18 people
- Sponsor
- Altor BioScience
Acute Respiratory Distress Syndrome, Pneumonia in Children
Using Artificial Intelligence To Improve Ventilator Settings For Intensive Care Patients
This observational study aims to determine whether an AI-assisted decision support system can improve clinical outcomes for mechanically ventilated pediatric patients (aged 1 month to 18 years) in the PICU, compared to standard…
- Conditions
- Acute Respiratory Distress Syndrome, Pneumonia in Children, Respiratory Failure (Pediatric Patients)
- Trial name
- NCT07592039
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Wu Rongzhou
Acute Respiratory Distress Syndrome, Prone Position
Effect of PP in Patients With Ultra-low VT
Acute respiratory distress syndrome (ARDS) is a heterogeneous syndrome with similar clinicopathological feathers caused by different etiologies.
- Conditions
- Acute Respiratory Distress Syndrome, Prone Position, Tidal Volume
- Trial name
- NCT06215209
- Testing
- position
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Southeast University, China
Misoprostol, Respiratory Distress Syndrome (RDS) of Neonate
Misoprostol Before Caesarean Section
The aim of our study is to evaluate the efficacy of Misoprostol before elective cesarean section in pregnant women with gestational age less than 38 weeks for preventing the occurrence of neonatal respiratory morbidity.
- Conditions
- Misoprostol, Respiratory Distress Syndrome (RDS) of Neonate, Caesarean Section
- Trial name
- Miso/CS (NCT06946914)
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Respiratory Distress Syndrome
n-CPAP Versus n-BiPAP and NIPPV for Postextubation in RDS in Preterms
non-invasive ventilation in preterms complaining from RDS a randomized, controlled trial to compare between capap, n-bipap and NIPPV
- Trial name
- NCT01770925
- Testing
- N-CPAP, n-BiPAP, NIPPV
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Invasive Mechanical Ventilation, Severe Respiratory Distress Syndrome
Little Lungs Study
This clinical trial is being done to evaluate the safety and clinical response of late surfactant treatment with budesonide in extremely preterm infants requiring mechanical ventilation at 7-14 days of age.
- Trial name
- NCT06855043
- Testing
- Calfactant, Budesonide
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- University of Wisconsin, Madison
Transient Tachypnea of the Newborn
Physiologically Based Cord Clamping To Improve Neonatal Outcomes After Elective Cesarean Delivery
Before birth, the baby's lungs are filled with fluid and babies do not use the lungs to breathe, as the oxygen comes from the placenta. As delivery approaches, the lungs begin to absorb the fluid.
- Trial name
- PhyCord1 (NCT06278415)
- Testing
- Physiological based cord clamping, Differed cord clamping
- Where
- 2 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Queen Fabiola Children's University Hospital
Respiratory Failure, Acute Respiratory Distress Syndrome
Cross-section Survey of Mechanical Ventilation and Acute Respiratory Distress Syndrome in China
The characteristics and outcomes of a mixed group of critically ill patients who received mechanical ventilation are not known in China.
- Trial name
- NCT01666834
- Where
- China
- Volunteers
- 555 people
- Sponsor
- Southeast University, China
Respiratory Distress Syndrome
Electrical Activity of Diaphragm as a Means to Predict Extubation Success in Preterm Infants
Mechanical ventilation used to support the sick newborn infant is associated with many complications including the development of chronic lung disease.
- Trial name
- Edi (NCT02144363)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Respiratory Distress Syndrome of Newborn, Threatened Premature Labor, Antepartum
Clinical Pharmacology of Dexamethasone in Pregnant Women With Preterm Labor
This study through to the pregnant woman blood concentrations of dexamethasone therapy after research, explore the pharmacokinetic data of dexamethasone in pregnant women, Chinese pregnant women dexamethasone pharmacokinetic…
- Trial name
- NCT05207852
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Dongyang Liu
ARDS, Human, Ventilation Therapy; Complications
Assessment of the Hemodynamic Effects of PEEP According to Alveolar Recruitment During the ARDS
The corner stone of the treatment of ARDS is mechanical ventilation with high levels of positive end-expiratory pressure, also called PEEP. A high level of PEEP is recommended and frequently used.
- Conditions
- ARDS, Human, Ventilation Therapy; Complications, Alveolar; Disorder
- Trial name
- NCT05524558
- Testing
- Pulmonary artery catheter, Esophagal pressure
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Bicetre Hospital
Spontaneous Subarachnoid Hemorrhage
Baricitinib for the Lung Injury Following Spontaneous SAH
The present study is a randomized, parallel control, and double-blind trial designed to assess the efficacy of baricitinib in reducing the occurrence of pulmonary complications in patients with spontaneous subarachnoid hemorrhage…
- Trial name
- BLISS (NCT06439615)
- Testing
- Baricitinib 4 MG, Standard treatment
- Volunteers
- 100 people
- Sponsor
- Tang-Du Hospital
Pregnancy, Respiratory Distress Syndrome
Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial
This is a randomized placebo controlled trial to evaluate whether antenatal corticosteroids can decrease the rate of neonatal respiratory support, thus decreasing the rate of NICU admissions and improving short-term outcomes in…
- Conditions
- Pregnancy, Respiratory Distress Syndrome, Pregnancy Outcomes, Preterm Birth
- Trial name
- ALPS (NCT01222247)
- Testing
- Betamethasone
- Where
- 17 sites in United States
- Volunteers
- 2,831 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
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