Clinical trials: Acute Stroke Intervention
Stroke, Neurologic Disorder
Evaluation of Bioness Integrated Therapy System (BITS) Touch Screen Technology to Improve Field Awareness
The Bioness Integrated Therapy System (BITS) (Bioness Inc. Valencia, CA) Touch Screen is an FDA approved device comprised of an interactive touchscreen and diverse program options to challenge patients through the use of visual…
- Conditions
- Stroke, Neurologic Disorder, Traumatic Brain Injury, Acquired Brain Injury
- Trial name
- NCT04930822
- Testing
- Table Top Visual Intervention, Bioness Integrated Therapy System Visual Intervention
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Gaylord Hospital, Inc
Stroke, Acute
A Study to Evaluate the DAISe System During Neurointervention for Acute Ischemic Stroke
This purpose study is to demonstrate the safety and performance of the DAISe System used to remove clot in the brain during a stroke.
- Trial name
- NCT03957278
- Testing
- DAISe System
- Where
- 2 sites in Belgium
- Volunteers
- 4 people
- Sponsor
- MIVI Neuroscience, Inc.
Acute Ischemic Stroke
Acute Ischemic Stroke Interventional Study
To assess safety of single IV (bolus + infusion) doses of ACT017 in patients with an acute ischemic stroke in addition to best emergency standard of care (including fibrinolysis by rtPA with or without added thrombectomy), with a…
- Trial name
- ACTIMIS (NCT03803007)
- Testing
- Intravenous ACT017 1000 mg
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Acticor Biotech
Acute Ischemic Stroke
Reperfuse Ischemic Vessels With Endovascular Recanalization Device in JAPAN (RIVER JAPAN)
The main objective of this study is to document that the thrombectomy catheter (Rev-01) is effective and safe when used for revascularization in subjects with acute ischemic stroke within 8 hours of symptom onset who are…
- Trial name
- NCT01895634
- Testing
- Rev-01
- Where
- Japan
- Volunteers
- 49 people
- Sponsor
- Johnson & Johnson K.K. Medical Company
Dyslipidemias, Stroke, Acute Ischemic
A Multicenter Study to Evaluate the Effect of High Dose Rosuvastatin Versus Rosuvastatin and Ezetimibe in Stroke
High-intensity statins are recommended for secondary prevention of stroke in patients with atherosclerotic ischemic stroke. According to the guidelines of the American Heart Association and the American Stroke Society…
- Trial name
- NCT05884502
- Testing
- combination of high-dose rosuvastatin and ezetimibe, high-dose rosuvastatin single administration
- Where
- 3 sites in South Korea
- Volunteers
- 330 people
- Sponsor
- Korea University Anam Hospital
Stroke
Clinical Assessment of Spatial Neglect Following Stroke
Spatial neglect (SN) is a common heterogeneous cognitive affliction that predicts poor recovery after a stroke. It is important to identify SN so alliviating actions can be initated.
- Trial name
- NCT04072614
- Where
- Iceland
- Volunteers
- 1,000 people
- Sponsor
- Landspitali University Hospital
Suspected Stroke
Early Initiated Ambulance-delivered Levetiracetam and Headposition in Hyper-acute Stroke Trial
This is an investigator initiated and conducted, multicentre, ambulance-delivered, prospective, randomised, open-label, blinded outcome (PROBE) study.
- Trial name
- EAST (NCT06773364)
- Testing
- Levetiracetam, Guide-recommended management, The lying flat (0°) head position
- Where
- 2 sites in China
- Volunteers
- 2,423 people
- Sponsor
- Shanghai East Hospital
Ischemic Stroke
Study of Tenecteplase Versus Alteplase for Thrombolysis (Clot Dissolving) in Acute Ischemic Stroke
BACKGROUND: Alteplase dissolves blood vessel clots in acute ischemic stroke and is the only approved acute drug treatment <4½ hours of stroke onset.
- Trial name
- NOR-TEST (NCT01949948)
- Testing
- Tenecteplase, Alteplase
- Where
- 13 sites in Norway
- Volunteers
- 1,050 people
- Sponsor
- Lars Thomassen
Acute Ischemic Stroke
Thrombectomy Using Pulsed Aspiration for Reperfusion of Brain Occlusions
The goal of this clinical trials is to demonstrate the safety and effectiveness for the RapidPulseTM Aspiration System in patients experiencing acute ischemic stroke within 8 hours of symptom onset or last seen normal.
- Trial name
- TURBO (NCT06029491)
- Testing
- RapidPulseTM Aspiration System
- Where
- 30 sites in United States, France and 2 more
- Volunteers
- 170 people
- Sponsor
- RapidPulse, Inc
Hemorrhagic Stroke
The Effect of Early Mobilization in Mild to Moderate Hemorrhagic Stroke
This study aims to examine the outcomes of early mobilization and early intervention within 24-72 hours after the onset of hemorrhagic stroke in patients admitted to an intensive care unit within 24 hours after stroke.
- Trial name
- NCT03292211
- Testing
- early mobilization, early standard intervention
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Stroke Acute
Efficacy of Five Strategies To Improve Stroke Awareness in the Spanish-Speaking Population
The goal of this experimental study is to evaluate the efficacy of five educational strategies for recognizing early symptoms of cerebrovascular disease (CVD) in the general adult population.
- Trial name
- NCT06613828
- Testing
- Mnemonic-Based Educational Training for Stroke Symptom Recognition
- Where
- Mexico
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Stroke, Acute Ischemic, Brain Hemorrhage
Neuropsychological Rehabilitation Over the Internet
Helsinki University Hospital (HUS) has decided on a strategy to provide digital health care services for several medical specialties - a project called the Health Village (HealthVillage.fi).
- Conditions
- Stroke, Acute Ischemic, Brain Hemorrhage, Encephalitis, Hypoxia-Ischemia, Brain
- Trial name
- IRENE (NCT05413733)
- Testing
- Digital care pathway, Care as usual
- Where
- Finland
- Volunteers
- 21 people
- Sponsor
- Helsinki University Central Hospital
Brain Infarction
Flying Intervention Team for Endovascular Treatment of Acute Ischemic Stroke in Rural Areas
The aim of this study is to compare time delay and safety parameters of stroke patients initially admitted to a rural primary stroke center (PSC) who receive endovascular treatment (EVT) by a Flying Intervention Team with…
- Trial name
- FIT (NCT04270513)
- Testing
- Endovascular treatment by Flying Intervention Team
- Where
- Germany
- Volunteers
- 477 people
- Sponsor
- Munich Municipal Hospital
Ischemic Stroke
The Norwegian Sonothrombolysis in Acute Stroke Study Part 2
BACKGROUND: Thrombolytic drugs may dissolve blood vessel clots in acute ischemic stroke. The overall benefit of intravenous thrombolysis is substantial, but up to 2/3 of patients with large clots may not achieve re-opening of the…
- Trial name
- NOR-SASS 2 (NCT01949961)
- Testing
- Ultrasound
- Where
- Norway
- Volunteers
- 59 people
- Sponsor
- Haukeland University Hospital
Stroke, Stroke Acute
Mechanical Thrombectomy in the Middle East and North Africa: Interim Results from the MEMENTO Registry
The MEMENTO (MEchanical thrMobectomy NETwork for MENA TOgether) Registry is a multicenter, prospective observational study aiming to evaluate the effectiveness, safety, and cost-effectiveness of mechanical thrombectomy (MT) in…
- Conditions
- Stroke, Stroke Acute, Endovascular Procedures, Large Vessel Occlusion
- Trial name
- MEMENTO Regist (NCT06702787)
- Where
- Egypt
- Volunteers
- 1,500 people
- Sponsor
- Middle East North Africa Stroke and Interventional Neurotherapies Organization
Dysphagia
Behavioural Intervention for Dysphagia in Acute Stroke
Swallowing dysfunction after stroke is common, but there is no reliable evidence for how it should be managed other than perhaps by nasogastric tube.
- Trial name
- NCT00257764
- Testing
- behavioral swallowing exercises/ strategies
- Where
- Australia
- Volunteers
- 300 people
- Sponsor
- Royal Perth Hospital
Stroke, Upper Extremity Paresis
The Application of a Mental Practice Protocol in the Acute Inpatient Rehabilitation Setting
The purpose of this randomized controlled trial is to compare the effect of audio-guided mental practice (MP) and video-guided MP on the impairment and functional abilities of upper extremity (UE) hemiparesis following a stroke.
- Trial name
- NCT04927728
- Testing
- Mental Practice, Repetitive-Task Practice, Traditional Therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Adventist HealthCare
Acute Stroke, Surgical Procedure
Emergent Microsurgical Intervention in Acute Stroke Patients After Mechanical Thrombectomy Failure Trial
With all of the gains that have been achieved with endovascular mechanical thrombectomy revascularization and intravenous thrombolysis logistics, there is still a subgroup of patients with salvageable brain tissue for whom…
- Trial name
- EMIAS (NCT05153642)
- Testing
- Microsurgical intervention
- Where
- 2 sites in Czechia
- Volunteers
- 50 people
- Sponsor
- University Hospital Ostrava
Ischemic Stroke
Intervention to Bridge the Evidence-based Gap in Stroke Care Quality
The purpose of this study is to evaluate whether a multifaceted quality improvement intervention can improve the adherent rate of individual and composite of evidence-based performance measures for patients with acute ischemic…
- Trial name
- GoldenBridge (NCT02212912)
- Testing
- improvement intervention, no intervention
- Where
- China
- Volunteers
- 4,800 people
- Sponsor
- Beijing Tiantan Hospital
Stroke
Implementation of a HABIT-ILE Intervention at William Lennox Neurological Hospital (NeuREHA) - Adult
Using a randomized controlled trial design, in an hospital environment, possible changes induced by the "Hand-arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE)" treatment program will be investigated in…
- Trial name
- Ad-NeuREHA (NCT06931795)
- Testing
- HABIT-ILE, Conventional intervention
- Where
- 3 sites in Belgium
- Volunteers
- 40 people
- Sponsor
- Université Catholique de Louvain