Clinical trials: Acute Wound
COVID-19, Acute Kidney Injury
Kidney Disease After COVID-19
To understand the long-term epidemiology, develop effective risk-prediction and stratification tools, and understand the pathobiology of kidney disease in COVID-19 survivors.
- Conditions
- COVID-19, Acute Kidney Injury, Chronic Kidney Injury
- Trial name
- NCT05328986
- Where
- 5 sites in United States
- Volunteers
- 1,753 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Acute Kidney Injury
Acute Kidney Injury in Pediatric Polytrauma Patients at Assiut University Trauma Unit: A Cross-Sectional Study on Incidence and Predictive Risk Factors
This study aims to investigate the true incidence and clinical presentation of post-traumatic AKI in hospitalized pediatric patients and identify the risk, and severity of AKI.
- Trial name
- NCT06177886
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Drug-Induced Acute Liver Injury
Macrophage Markers, Soluble CD163 (sCD163) and Soluble CD206 (sCD206) in Paracetamol Overdose
Paracetamol (PCM) is a widely used over-the-counter analgesic, and overdose with PCM is a condition regularly seen in everyday clinical practice.
- Trial name
- NCT03679442
- Testing
- N-acetylcysteine
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Acute Kidney Injury, Chronic Kidney Disease
Long Term Impact of Pediatric Acute Renal Injury in Severe Sepsis
Sepsis is the most common cause of childhood death worldwide. Millions of children survive, but are left with impaired health. Sepsis-related Acute Kidney Injury (sAKI) is increasingly recognized as a significant factor…
- Conditions
- Acute Kidney Injury, Chronic Kidney Disease, Hypertension
- Trial name
- IMPRESS (NCT02372721)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Emergencies
The Greek Acute Dance Injuries Registry
Dance is a highly demanded physical activity with a high rate of acute and emergent events (AEE). No systematic prospective study has been conducted in any Greek population of dance students for the registration of the AEE and…
- Trial name
- GrADIR (NCT06220916)
- Testing
- Dance training in Classical Ballet and Contemporary Dance
- Where
- Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Pain, Muscle, Pain, Acute
Arnica and the Management of Pain in Acute Musculoskeletal Extremity Injuries
In the Emergency Department, there is no standard of care for pain medication distribution for children with an acute musculoskeletal injury when there is no fracture present.
- Trial name
- NCT05283434
- Testing
- Arnica
- Where
- 2 sites in United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Sickle Cell Disease, Kidney Injury
Acute Kidney Injury in Patients With Sickle Cell Disease
Patients with sickle cell disease may be at risk for acute kidney injury (AKI)during sickle cell crisis (pain or acute chest syndrome).
- Conditions
- Sickle Cell Disease, Kidney Injury, Kidney Diseases, Kidney Disease, Chronic
- Trial name
- NCT03105271
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Acute Respiratory Insufficiency, Chronic Respiratory Insufficiency
Pharmacokinetics of Nebulized Amikacin in Non Invasive Ventilated Healthy Volunteers.
The purpose of the study is to compare the pharmacokinetics of nebulized amikacin administered with three vibrating mesh nebulizers coupled with a single limb circuit bilevel ventilator in healthy volunteers.
- Conditions
- Acute Respiratory Insufficiency, Chronic Respiratory Insufficiency, Bronchospasm and Obstruction
- Trial name
- NIV-NEBU (NCT01901497)
- Testing
- Nebulizer
- Where
- Belgium
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University Hospital St Luc, Brussels
Early Diagnosis of Acute Kidney Injury
Early Prediction and Diagnosis of Acute Kidney Injury
The goal of this clinical trial is to estimate the accuracy of renal resistive index in early diagnosis and prediction of acute kidney injury in patients with hemorrhagic stroke.
- Trial name
- NCT07181174
- Testing
- Ultrasonographic examination and doppler ultrasonography will be performed using a convex transducer.
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Aswan University
Spinal Cord Injuries
Repetitive Acute Intermittent Hypoxia for Spinal Cord Repair
Our goal is to enhance repeated exposure to acute intermittent hypoxia (rAIH)/training-induced aftereffects on upper and lower limb function recovery in humans with chronic spinal cord injury (SCI).
- Trial name
- NCT03433599
- Testing
- Repeated exposure to acute Intermittent Hypoxia (rAIH), Normal Room Air, Upper-limb Training by Research Staff
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Sepsis, Acute Kidney Injury Due to Sepsis
Renin Angiotensin Aldosterone System In Septic Kids
Prospective observational cohort study; pediatric sepsis vs. healthy pediatric subjects and pediatric sepsis with acute kidney injury (AKI) vs without AKI.
- Conditions
- Sepsis, Acute Kidney Injury Due to Sepsis, Acute Kidney Injury (Nontraumatic)
- Trial name
- RISK (NCT06295393)
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Acute Myocardial Infarction, Ischemia-reperfusion Injury
Combined Antioxidant Therapy Against Myocardial Reperfusion Injury. Phase I Study.
Background: Acute myocardial infarction (AMI) has remained a leading cause of mortality and disability worldwide. Although percutaneous coronary angioplasty (PCA) is the best treatment for these patients, paradoxically this…
- Conditions
- Acute Myocardial Infarction, Ischemia-reperfusion Injury, Reperfusion Injury, Myocardial, Reperfusion Arrhythmias
- Trial name
- NCT05215743
- Testing
- Antioxidant therapy, NaCl 0.9%
- Where
- Chile
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Chile
Renal Insufficiency, Acute
Evaluation of the Renal Function in an Ultra-endurance Race.
During ultra endurance events, athletes experience extreme physical and mental demands, sometimes at the limits of the adaptive response to human physiology.
- Trial name
- INFERNAL (NCT03136315)
- Testing
- INFERNAL Intervention
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Trauma, Acute Hemorrhage
Evaluation of a Transfusion Therapy Using Whole Blood in the Management of Coagulopathy in Patients With Acute Traumatic Hemorrhage
The prognosis of traumatized hemorrhages is correlated with the nature of transfusion therapy: a 50% reduction in mortality for an early and massive supply of plasma, and 20% for an early and massive supply of platelets.
- Conditions
- Trauma, Acute Hemorrhage, Coagulopathy
- Trial name
- T-STORHM (NCT04431999)
- Testing
- Whole blood transfusion, Fractionated blood products transfusion
- Where
- 6 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Strains
Acute Hamstring Strains in Danish Elite Soccer - Diagnosis and Biomechanical Tests
A common soft tissue injury in sports involving sprinting and jumping is the hamstring strain. In addition to the frequency of injury, hamstring injuries are also the most recurrent soft tissue injury occurring in sport.
- Trial name
- NCT00556517
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amager Hospital
Physical Fatigue, Return to Sport
The Effect of Physical Fatigue on Lower Limb Functional Performance Tests in a Healthy Population
The main objective of this project is: 1. To assess the influence of physical fatigue on a return-to-play test battery in a healthy population. In a later stage, these experiments could be carried out in a clinical context (e.g.
- Conditions
- Physical Fatigue, Return to Sport, Injury Prevention, Functional Performance
- Trial name
- NCT04029935
- Testing
- Physical Fatigue, Control
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Renal Disease, End-Stage, Renal Insufficiency, Chronic
Bosutinib In Subjects With Renal Impairment
This is a two-staged study of a single dose of 200 mg of bosutinib given to subjects with renal impairment and matching healthy volunteers.
- Conditions
- Renal Disease, End-Stage, Renal Insufficiency, Chronic, Renal Insufficiency, Acute
- Trial name
- NCT01233882
- Testing
- Bosutinib
- Where
- 5 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Pfizer
Caffeine, Biomechanics
Effects of Caffeine Ingestion on the Biomechanics of Healthy Young Subjects
Caffeine is one of the few supplements that have enough scientific evidence to state that can notably improve performance, as different remarkable organizations in the sports nutrition context have classified it as an ergogenic…
- Conditions
- Caffeine, Biomechanics, Fatigue, Injuries
- Trial name
- NCT06039358
- Testing
- Caffeine., Cellulose.
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Athletic Injuries
FITLIGHT Reliability and Acute Training Effects
The purpose of this study is to assess the reliability of outcomes collected using a speed and cognitive light training system. This study will also be used to understand the effects of brain training on athletic performance…
- Trial name
- NCT06748417
- Testing
- Acute Cognitive Training, Non-stimulating Rest
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Miami
Acute Kidney Injury
Differential Adaptation of Renal Function in Intense Physical Exercise
In recent years there has been a significant increase in the number of participants in high intensity and duration sports events.
- Trial name
- NCT04929418
- Testing
- 10 km continuous running, 1.5 km continuous swimming
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Clínico Universitario de Valladolid