Clinical trials: Adaptation
Genetic Disease, Communication
The Role of Family Functioning in Promoting Adaptation in Siblings of Individuals With Duchenne Muscular Dystrophy (DMD)
Background: We want to learn more about the relationship between the way families function and how children adapt to having a sibling with Duchenne muscular dystrophy (DMD).
- Trial name
- NCT01386515
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Body Temperature Changes, Heat Exposure
Preparing for Heat Waves - Enhancing Human Thermophysiological Resilience
As the ongoing progression of climate change exposes individuals to elevated temperatures and an escalating frequency of extreme heat events, the risk of more intense and prolonged heat waves raises significant concerns for…
- Conditions
- Body Temperature Changes, Heat Exposure, Heat Stress, Hyperthermia
- Trial name
- Prep4heat (NCT06389604)
- Testing
- Heat acclimation
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Monckeberg Medial Calcific Sclerosis
Mechanical Stress Effects on the Cardiovascular Adaptations of Peripheral Arterial Calcifications Among Athletes
The main objective of this study is to obtain data for the integrated analysis of morphological, functional and biomechanical parameters pertaining to lower limb arteries in various categories of elite athletes (without…
- Trial name
- MediaSport (NCT01577576)
- Where
- 2 sites in France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Functional Mobility, Virtual Reality-Based Functional Assessment
Virtual Reality-Based Timed Up and Go Test in Young Adults
Functional mobility encompasses the essential motor skills required for individuals to perform activities of daily living independently and safely.
- Trial name
- NCT07362004
- Testing
- Clinical Assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Memory Disorders, Neurocognitive Disorders
Creation of an Ecological Tool Assessing Episodic Memory in Geriatrics
In this study the participants can be recruited via scheduled consultation and external institutions (associations, senior club..).
- Trial name
- ECOTESTGER (NCT05668598)
- Testing
- ecological MAI test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Lens
Physical Therapy Education, Clinical Judgement Assessment
Interrater Reliability and Feasibility of the Lasater Clinical Judgment Rubric for Use in Physical Therapy Simulation
This study examines whether physical therapy faculty can reliably and feasibly use the Lasater Clinical Judgment Rubric adapted for physical therapy (LCJR-PT) to score students' clinical judgment during a recorded simulation…
- Conditions
- Physical Therapy Education, Clinical Judgement Assessment, Simulation-based Learning
- Trial name
- NCT07449026
- Testing
- Video Recorded Acute Care Simulation, Faculty Rating of Acute Care Simulation Video Using the LCJR-PT
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Youngstown State University
Suicide, Depression
Adaptation of a French E-health Tool for Suicide Prevention in Young Populations
"France's suicide rate is among the highest in Europe, with the young among the more at risk. Several European projects have demonstrated the effectiveness of using e-tools in suicide prevention particularly for hard-to-reach…
- Conditions
- Suicide, Depression, Psychological Distress, Anxiety Disorders
- Trial name
- E-psYouth (NCT04946955)
- Testing
- Application and website with or without promotion
- Where
- France
- Volunteers
- 12,000,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity, Physical Inactivity
Effects of Short Isokinetic Eccentric Resistance Training on Neuromuscular Induced Adaptations
The study compares the impact of isokinetic resistance training (RT) -induced neuromuscular adaptation following an 8-week short ECC ISO RT and CON ISO RT among obese, untrained women. The main question it aims to answer is: 1.
- Trial name
- NCT07407621
- Testing
- ECC ISO, CON ISO
- Where
- Malaysia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Pregnancy Related, Heart Rate Variation (HRV)
Cardiovascular Research in EMbarazo and MAternity (EMMA). Study on Heart Rate Variability and Hemodynamic Adaptations During Pregnancy and Postpartum.
Heart rate variability (HRV) provides a non-invasive assessment of autonomic control of the nervous system over the heart. During pregnancy, the cardiovascular system adapts significantly, affecting HRV and hemodynamics.
- Conditions
- Pregnancy Related, Heart Rate Variation (HRV), Hemodynamics
- Trial name
- EMMA (NCT07376616)
- Testing
- Assessment of HRV and blood pressure
- Where
- Spain
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Healthy Normal Weight Women, Constitutionally Lean Women
Management of Constitutional Thinness Through an Adapted Physical Activity Program, Whether or Not Associated With Food Supplementation. Interventional Study Compared to Matched Controls: NUTRILEAN + Study
The main aim of the present study is to compare the effect of a 12-week physical activity program on body weight gain and body composition changes between normal weight and constitutionally lean individuals.
- Trial name
- NUTRILEAN + (NCT04749706)
- Testing
- Physical training alone, physical training + protein intake
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Vegan Diet, Body Composition
Acute Metabolic Response Versus Long-term Adaptation to a Vegan Diet
At baseline, venous blood samples were collected from all eligible participants. The following biochemical parameters were analysed: serum electrolytes (mineral profile), fasting glucose, creatinine, urea nitrogen, total…
- Conditions
- Vegan Diet, Body Composition, Quality of Life (QOL), Cardiometabolic Health
- Trial name
- VITAL (NCT07731633)
- Testing
- vegan diet
- Where
- Slovakia
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University Hospital, Martin
Obesity & Overweight
Long-term Adaptations of Skeletal Muscle After Hybrid Training
Obesity is a major challenge for public health and renders it imperative to reduce its prevalence. High intensity interval training (HIIT) is a form of exercise training that can efficiently induce weight loss in adults with…
- Trial name
- NCT07341711
- Testing
- Exercise training, Control group
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Healthy, Healthy Participants
Acute Effects of Structured Exercise and Static Stretching on Vascular Function, Neuromuscular Performance, and Metabolic Regulation in Adults
This experimental study investigates the acute cardiovascular and vascular responses to a single session of resistance training, with and without additional static stretching, compared with a resting control condition.
- Conditions
- Healthy, Healthy Participants, Healthy Subjects (HS), Resistance Training Adaptation
- Trial name
- NCT07364149
- Testing
- Resistance Training, Resistance training + Static Stretching
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Probiotics
The Effect of a Multi-strain Probiotic on Acclimatization to High Altitude
The goal of this study is to learn if the probiotic SLAB51 (Sivomixx800®) works to enhance acclimatization to high altitude in humans.
- Trial name
- NCT06552806
- Testing
- SLAB51
- Where
- 2 sites in United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Psychological Adaptation, Psychology, Social
Psychological Impact of the Health Measures Generated by the COVID19 in Adolescents
The lockdown of the French population is a health measure put in place in response to the pandemic linked to a new coronavirus, SARS-CoV-2 (Covid-19).
- Trial name
- COVADO (NCT04406558)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Psychosomatic Disorder, Psychological Distress
Feasibility and Benefits of Digital Services During the COVID19 Pandemic
As a result of the pandemic, hygiene and distancing rules must be followed in Health care/ rehabilitation clinics to ensure the safety of patients and staff.
- Conditions
- Psychosomatic Disorder, Psychological Distress, Psychological Stress, Psychological Disease
- Trial name
- AnhandCOV19 (NCT04453475)
- Testing
- Training session adressing information and health literacy
- Where
- Germany
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Mindfulness, Emotional Well-being
MBSR in a Hispanic Immigrant Population in St. Louis
Hispanics are the largest ethnic group in the US as well as the fastest growing. Yet, despite being such a large population group, Hispanics are under-studied and under-represented in most studies of health, psychological…
- Trial name
- NCT03839589
- Testing
- Mindfulness Based Stress Reduction Adapated (MBSR-A)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Postoperative Recovery, General Anaesthesia
Intercultural Adaptation and Validation of the Ukrainian Quality of Recovery-15 Questionnaire
The Quality of Recovery 15-questionnaire (QoR-15) is used to assess postoperative quality of recovery after surgery and anesthesia from the patient's perspective.
- Conditions
- Postoperative Recovery, General Anaesthesia, Validation, Questionnaire
- Trial name
- NCT07510360
- Testing
- Quality of Recovery-15 questionnaire, Ukrainian version
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rostyslav Voloshchuk
Depression Disorders, Suicidality
Effectiveness of the Adapt for Life, Mental Wellness and Suicide Prevention Program
Adapt for Life is a mental health and wellbeing program designed to help young people develop healthy behaviors and important life skills to manage stress and mental health challenges.
- Trial name
- AFL (NCT06979479)
- Testing
- school-based intervention
- Where
- United States
- Volunteers
- 1,102 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Dementia, Memory Impairment
Cultural and Linguistic Adaptation and Normative Study of the Turkish Version of the Free and Cued Selective Reminding Test: 16-Word Version (FCSRT-T)
An Adaptation Study of Free and Cued Selective Reminding Test in Turkish
- Trial name
- FCSRT-T (NCT05756231)
- Testing
- SIHT-16
- Where
- Turkey (Türkiye)
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Istanbul University