Clinical trials: Adaptation
Adaptation Reaction
Effects of Prolonged Roll-tilt in Healthy Human Subjects
The long-term goal of this research is to advance the investigators knowledge of how the brain combines the information of multiple sensory systems coding for spatial oriention and how adaptation to vestibular imbalance…
- Trial name
- NCT02980419
- Testing
- presentation of visual and vestibular stimuli
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Disparities, Community Health Workers
Philly CEAL- DECIDE+ Adaptation
Cardiovascular disease (CVD) disproportionately affects racial/ethnic minorities and underserved populations in Philadelphia. This study aims to evaluate the effectiveness of an enhanced community health worker (CHW) program that…
- Conditions
- Disparities, Community Health Workers, Cardiovascular Diseases, Social Determinants of Health (SDOH)
- Trial name
- NCT06732102
- Testing
- DECIDE, Community Health Worker Support
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Injury;Sports
Comparison of Architectural and Performance Adaptations of Hip Extension Exercise Under Gravitational or Inertial Loading Conditions
The main objective of this study is to investigate training-induced adaptations in Biceps femoris long head (BFlh) architecture and performance measures such as muscle strength, jumping, and power variables after following 6…
- Trial name
- NCT06538467
- Testing
- Hip extension exercise with inertial load, Hip extension exercise with gravitational load
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Child Development
Arabic Ages and Stages Questionnaire-III
Early detection and intervention for developmental delays are crucial in promoting healthy child development, hence the need for formal screening.
- Trial name
- NCT02539251
- Testing
- Arabic ASQ -3
- Where
- Lebanon
- Volunteers
- 527 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Myopia
Performance of Somofilcon A Over One Week in Wearers Adapted to Omafilcon A
The objective of the study is to determine if habitual or adapted contact lens wearers of Omafilcon A can be confidently refit into Somofilcon A lenses and be successful after one week of daily wear.
- Trial name
- NCT03226353
- Testing
- somofilcon A, omafilcon A
- Where
- Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Pressure Ulcer, Sleep Disorder
Adaptation of Mattresses Made With Different Materials to Personal Anthropometry Values and Body Postures
Sleep disorders affect 40% of the adult population each year and are often associated with morbidity and mortality (Kripke et al., 2002; F.-Z. Low et al., 2017).
- Conditions
- Pressure Ulcer, Sleep Disorder, Spine Degeneration, Body Structure, Altered From Its Original Anatomical Structure
- Trial name
- NCT05486039
- Testing
- Changing behaviour
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
HIV, Alcohol Consumption
Mentor Moms+ Study
The goal of this study is to adapt an existing evidence based intervention for use in pregnant and lactating people (PLP) who use alcohol.
- Trial name
- (MM+) (NCT06962592)
- Testing
- MM+, Enhanced HIV attention control (eSOC)
- Where
- 2 sites in South Africa
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Culture, Adaptation, Psychological
Effect of Cultural Marginality Theory-Based Education on Intercultural Adaptation and Psychological Well-Being of Foreign Nursing Students
In this study, between 1 - 31 December 2022, who met the inclusion and exclusion criteria, a total of 66 foreign nursing students who are with 1st year foreign students starting the Nursing Department of Ondokuz Mayıs University…
- Conditions
- Culture, Adaptation, Psychological, Psychological Well-being
- Trial name
- NCT05943639
- Testing
- The Cultural Marginality Theory-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Hilal Altundal
Metabolic Adaptation to High-Intensity Interval Training
Carbonic Anhydrase II Responses to Basketball-Specific High-Intensity Interval Training
This study aims to examine whether erythrocyte carbonic anhydrase II can be used as a biological marker of metabolic adaptation to basketball-specific high-intensity interval training.
- Trial name
- CAII-BASKET (NCT07377851)
- Testing
- Basketball-Specific High-Intensity Interval Training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Pregnancy, Childbirth
Adapted Safe Childbirth Checklist in Chiapas, Mexico
The purpose of this mixed methods study is to evaluate the implementation of an adapted Safe Childbirth Checklist in a rural hospital in Chiapas, Mexico. The study aims are: 1.
- Conditions
- Pregnancy, Childbirth, Quality of Care, Puerperium
- Trial name
- SCC-Chiapas (NCT02886364)
- Testing
- Adapted Safe Childbirth Checklist
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Diabetes (DM)
Role of Alpha-to-beta Cell Communication to Adapt Insulin Secretion to Insulin Resistance.
Glucagon secretion from α-cells has long been viewed as primarily a counterregulatory mechanism - e.g. an agent with a role to prevent blood sugar from decreasing to levels that compromise function.
- Trial name
- UPGRADE (NCT07224334)
- Testing
- Exendin-9 is a 30 amino acid peptide that is an established competitive antagonist of the GLP-1 receptor. Subjects will receive exendin-9 by intravenous infusion at a rate of 600 pmol/kg/min, Dexamethasone, Dextrose 20% solution
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- David D'Alessio, M.D.
Cancer Genetics
Adaptation to Living With a BRCA1/2 Mutation
Background: Women who have a BRCA1/2 gene mutation have a very high risk of developing breast or ovarian cancer. They are also at increased risk of other developing other cancers.
- Trial name
- NCT01866865
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Focus on Healthy Infants
Development of Muscle Function in Prepubertal Children As a Response to Growth and Resistance Training
Healthy skeletal muscle development is crucial for a life-long quality of life. Childhood and puberty may be key periods for developing muscle growth and neuromuscular capacities, which are essential for bone-muscle interaction…
- Trial name
- decade-fit (NCT06594900)
- Testing
- resistance training intervention
- Where
- Switzerland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ralf Roth
Healthy Adult, Cyclists
Musculotendinous Adaptations to Strength and Endurance Training in Cyclists
This study investigated whether adding strength training to regular endurance training improves performance and muscle function in competitive cyclists.
- Conditions
- Healthy Adult, Cyclists, Athletes
- Trial name
- STEND (NCT07658300)
- Testing
- Strength training, Endurance training
- Where
- Lithuania
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Translation, Cultural Adaptation and Turkish Validation
Translation, Cross-Cultural Adaptation and Turkish Validation of the 25-Question Geriatric Locomotive Function Scale
25-question Geriatric Locomotive Function Scale (GLFS-25) is a patient-reported outcome measure consisting of 25 questions that evaluates locomotive functions and locomotive syndrome risk in elderly individuals.
- Trial name
- NCT05214755
- Where
- Turkey (Türkiye)
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Physical Inactivity, Health Behavior
The Turkish Version of the Self-perceived Barriers for Physical Activity Questionnaire
The Self-perceived Barriers for Physical Activity Questionnaire (SBPAQ) is originally developed in Spanish to evaluate self-perceived barriers for physical activity participation in healthy individuals.
- Conditions
- Physical Inactivity, Health Behavior, Quality of Life
- Trial name
- NCT05512936
- Where
- Turkey (Türkiye)
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Aging, Mobility Limitation
Evaluating Implementation and Impact of Provincial Scale-up of the Adapted Choose to Move (CTM) Program
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Aging, Mobility Limitation, Physical Inactivity, Loneliness
- Trial name
- NCT06446414
- Testing
- Choose to Move
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Premature Birth, Hypoxia
Hypoxia Intolerance in Preterm Individuals
Reduced Hypoxic Ventilatory Response (HVR) and systemic O2 saturation subsequently leading to blunted aerobic capacity as well as decreased overall physical and cognitive performance are the main physiological challenges faced by…
- Trial name
- PreAlti (NCT04739904)
- Testing
- Normoxia, Normobaric hypoxia, Hypobaric hypoxia
- Where
- 3 sites in Slovenia, Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Jozef Stefan Institute
Emergence Delirium, Anesthesia
Turkish Version of The Pediatric Anesthesia Emergency Delirium
Emergence delirium (ED) is a mental disorder seen in children during recovery from general anesthesia. The Pediatric Anesthesia Emergence Delirium (PAED) scale is the only valid scale to assess ED in pediatric patients undergoing…
- Trial name
- PAED (NCT06931249)
- Testing
- The observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Breast Cancer, Benign Breast Disease
Evaluating Scaleup of an Adapted Breast Cancer Early Diagnosis Program in Rwanda
Breast cancer incidence is increasing in low- and middle-income countries (LMICs) and breast cancer mortality is high in these regions largely due to late stage diagnoses.
- Conditions
- Breast Cancer, Benign Breast Disease, Cervix Cancer
- Trial name
- NCT05364138
- Where
- Rwanda
- Volunteers
- 2,357 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
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