Clinical trials: Addiction Disorders
Alcohol Dependence
The Self Match Study: A Study of Informed Choice in the Treatment of Addiction
The purpose of this study is to determine whether patient self-matching (as compared with treatment as usual by expert matching) improves quality of life, retention, and outcome for patients being treated for alcohol problems.
- Trial name
- NCT03278821
- Testing
- Self Match, Expert Match
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Kjeld Andersen
Cannabis Dependence
Social and Emotional Brain Function in Cannabis Users
The aim of this functional magnetic resonance imaging (fMRI) study is to find out whether and how social and emotional brain function are altered in dependent cannabis users relative to healthy non-using control subjects after a…
- Trial name
- NCT02711371
- Testing
- fMRI
- Where
- Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Domestic Violence, Substance Abuse
Treatment of Intimate Partner Violence and Substance Abuse in a Forensic Setting
Intimate partner violence is a significant societal problem. However, treatment of IPV perpetrators is far from effective, which may be partly due to the fact that the role of substance abuse is not taken into account.
- Trial name
- NCT00847548
- Testing
- substance abuse/domestic violence treatment, CBT addressing partner violence
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- VU University of Amsterdam
Substance Use, Substance Use Disorders
Peer-Delivered Behavioral Activation for Methadone Adherence - Pilot Phase
The purpose of this study is to evaluate the feasibility and effectiveness of a peer-led, brief, behavioral intervention to improve adherence to medication for opioid use disorder (MOUD) among low-income, minoritized individuals…
- Conditions
- Substance Use, Substance Use Disorders, Opioid-use Disorder, Peer Delivered
- Trial name
- HEAL Together (NCT04248933)
- Testing
- Peer-Delivered Behavioral Activation (Peer Activate)
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of Maryland, College Park
Drug Addiction
Recovery Housing For Drug Dependent Pregnant Women
For the past several years our research program has developed and tested an intensive outpatient intervention that is based in social learning theory and employs abstinence contingent access to recovery housing as a routine…
- Trial name
- HOME (NCT00497302)
- Testing
- RBT, usual care
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Johns Hopkins University
Schizophrenia, Nicotine Addiction
Effects of rTMS on Cigarette Smoking and Cognition in Schizophrenia
Cigarette smoking rates are extremely high in persons with schizophrenia and this increases the risk of disease and death due to tobacco-related disorders.
- Trial name
- rTMSsmokelab (NCT01523730)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Substance-related Disorders, Alcohol-Related Disorders
LaunchPad: Supporting Healthy Decisions and Preventing Drug Use After High School
LaunchPad is an online substance use prevention program for high school seniors. The program is designed to help seniors develop skills and make informed decisions as they transition from high school to young adulthood.
- Conditions
- Substance-related Disorders, Alcohol-Related Disorders, Tobacco Use Disorder, Marijuana Use
- Trial name
- NCT07655609
- Testing
- Introduction, Norms re: Protective Behavior Strategies (PBS), Life Skills
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Prevention Strategies, LLC
Substance Use Disorders, Treatment Adherence and Compliance
Kentucky Access to Recovery Evaluation
Evaluate the long-term effectiveness of implementing vouchers as a linkage strategy in a population requiring recovery support services (RSS) when no other funding sources are available.
- Trial name
- NCT05889702
- Testing
- KATR Linkage Strategy
- Where
- 2 sites in United States
- Volunteers
- 458 people
- Sponsor
- Terry Bunn
Marijuana Abuse
Efficacy and Safety of the Hcoil Deep TMS for the Treatment of Cannabis Addiction
Evaluation of efficacy and safety of H-coil deep transcranial magnetic stimulation 9 week treatment trial for cannabis addiction as assessed by measures of drug intake and craving.
- Trial name
- NCT00543036
- Testing
- H-Coil deep TMS
- Where
- Israel
- Sponsor
- Shalvata Mental Health Center
Regional Anesthesia, Anxiety
Uncontrolled Disinformation About Regional Anesthesia and Pregnant Patients.
Nowadays, hundreds of information about regional anesthesia are accessed from any internet search engine when a question is written about the methods of anesthesia that can be applied during C/S.
- Conditions
- Regional Anesthesia, Anxiety, Social Media Addiction, Spinal Anesthesia
- Trial name
- NCT05416541
- Testing
- social media
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Amphetamine-Related Disorders
A Cognitive Behavioral Therapy-Based Text Message Intervention for Methamphetamine Dependence
This Phase I behavior therapy development study seeks to improve treatment outcomes for methamphetamine (MA)-dependent subjects by developing a novel cognitive behavioral therapy- (CBT-) based short message service (SMS) text…
- Trial name
- NCT01899313
- Testing
- CBT- based SMS text messaging intervention, CBT group therapy
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- California Pacific Medical Center Research Institute
Nicotine Dependence
Do Flavors Increase the Addiction Potential of Nicotine?
The FDA has concluded that flavors (e.g. menthol) are associated with greater addiction potential in tobacco cigarettes (Gottlieb March 13, 2019).
- Trial name
- NCT04696380
- Testing
- Nicotine, JUUL e-cigarette
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Alcohol Dependence, Bipolar Disorder
Open Label Trial of Acamprosate in Bipolar Alcoholics
The purpose of this study is to determine whether acamprosate (Campral) is safe and effective in treating alcohol dependence in individuals with bipolar disorder.
- Trial name
- NCT00330486
- Testing
- Acamprosate
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Medical University of South Carolina
Opioid Use Disorder, Pain
Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Adults With an Opioid Use Disorder (EXPO; R33 Phase)
This work will involve conducting a randomized trial that will evaluate preliminary efficacy of "assisted" rate cycling, voluntary rate cycling and psychotherapy for pain individually and in combination as adjunctive treatments…
- Trial name
- EXPO-R33 (NCT05688410)
- Testing
- Exercise, Psychotherapy Pain and Addiction (I-STOP)
- Where
- 2 sites in United States
- Volunteers
- 198 people
- Sponsor
- Case Western Reserve University
Human Immunodeficiency Virus, Acquired Immunodeficiency Syndrome
Intervention of HIV, Drug Use and the Criminal Justice System in Malaysia
The purpose of this study is to evaluate the relative impact a medical drug (methadone) or behavioral counseling program (Holistic Health Recovery Program) or both (methadone and Holistic Health Recovery Program) has on reducing…
- Conditions
- Human Immunodeficiency Virus, Acquired Immunodeficiency Syndrome, Opiate Addiction, Drug Dependence
- Trial name
- Harapan (NCT02396979)
- Testing
- Methadone, Holistic Health Recovery Program
- Volunteers
- 300 people
- Sponsor
- Yale University
OCD, Major Depressive Disorder (MDD)
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
This is an observational study which does NOT directly administer a psychedelic substance but rather recruits participants who are already participating in another clinical trial in which they may receive a serotonergic…
- Conditions
- OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer
- Trial name
- NCT06624137
- Testing
- Serotonergic Psychedelic
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Yale University
Cocaine-Related Disorders, Heroin Dependence
Employment-based Reinforcement of Naltrexone Ingestion and Abstinence
A randomized study is planned over 5 years to evaluate the effectiveness of the Therapeutic Workplace in promoting naltrexone ingestion and abstinence in unemployed opiate-dependent injection drug users.
- Conditions
- Cocaine-Related Disorders, Heroin Dependence, Opioid-Related Disorders, Substance Abuse, Intravenous
- Trial name
- NCT00149669
- Testing
- employment-based reinforcement
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Johns Hopkins University
Normal Physiology, Alcohol Use Disorder
Addictions Neuroclinical Assessment (ANA)
Background: Alcohol use disorder (AUD) is a major public health problem. In the U.S., 16 to 18 million adults have an AUD. Researchers want to test an assessment tool called the ANA.
- Trial name
- NCT04946851
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Social Functioning, Addiction, Substance
Pain Clinic Provides Public Health Safety
Chronic pain is associated with psychological disorders; which may affect a patient's socioeconomic, legal, domestic, and employment situations.
- Conditions
- Social Functioning, Addiction, Substance, Safety Issues, Road Injury
- Trial name
- NCT06076512
- Testing
- Behavioral therapy
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Salem Anaesthesia Pain Clinic
Tobacco Use Disorder, Smoking Cessation
Deep rTMS and Varenicline for Smoking Cessation
The purpose of this study is to investigate the effect of deep repetitive transcranial magnetic stimulation (rTMS) using the insula H-coil on smoking outcomes in smokers receiving varenicline.
- Trial name
- NCT04083144
- Testing
- Deep Repetitive Transcranial Magnetic Stimulation (Active), Varenicline
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Centre for Addiction and Mental Health
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