Clinical trials: Addiction Disorders
Nicotine Dependance, Serious Mental Illness
Evaluation of Community Health Worker Support to Help People With Serious Mental Illness to Quit Smoking
The purpose of this study is to learn whether providing additional smoking cessation support through specially trained members of behavioral healthcare team helps people quit smoking and improve their health.
- Conditions
- Nicotine Dependance, Serious Mental Illness, Smoking (Tobacco) Addiction, Tobacco Cessation
- Trial name
- NCT07789132
- Testing
- Integrated CHW Support intervention, Enhanced usual care (EUC)
- Where
- United States
- Volunteers
- 937 people
- Sponsor
- Massachusetts General Hospital
Internet Addiction Disorder, Health Promotion
The Effect of Health Education on Digital Game Addiction and Health Promotion Behavior in Adolescents
This study aimed to evaluate the effectiveness of a school nurse-led health education program in reducing digital game addiction and improving health-promoting behaviors among adolescents.
- Conditions
- Internet Addiction Disorder, Health Promotion, Digital Game Addiction, Adolescent
- Trial name
- NCT07002515
- Testing
- Health Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Tension-Type Headache, Sleep Disturbance
Tension-type Headache and Its Association
To estimate the prevalence of tension-type headache among adults attending the outpatient clinics at Assiut University Hospitals, and to assess its association with smartphone use, sleep quality, and quality of life.
- Conditions
- Tension-Type Headache, Sleep Disturbance, Smartphone Addiction, Quality of Life
- Trial name
- NCT07779655
- Volunteers
- 199 people
- Sponsor
- Assiut University
Behavioral Intervention, Nicotine Addiction
Impact of Appointment Reminder Strategies on Smoking Cessation Clinic Attendance
The goal of this clinical trial is to learn whether different appointment reminder methods can improve attendance at an anti-smoking (smoking cessation) clinic among adult smokers.
- Trial name
- NO-SHOW-NCC (NCT07779161)
- Testing
- Standard phone call, phone call with MINDSPACE elements
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Medical University of Gdansk
Addiction, Opioid Use
Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion
The overall goal of this project is to collect initial human data on the effects of novel compounds on safety (interactions with an opioid drug, e.g., buprenorphine) and early efficacy signals (subjective effects on negative…
- Conditions
- Addiction, Opioid Use, Substance Use Disorders, Opioid Use Disorder
- Trial name
- NCT05976646
- Testing
- Auvelity
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Virginia Commonwealth University
Chronic Pain, Opioid Use Disorder
Pain Self-Management and Treatment Engagement for Patients Taking Opioids
The goal of this study is to learn if Pain Self-Management (PSM) can improve chronic pain care in individuals with opioid misuse or opioid use disorder (OUD) The main questions it aims to answer are: Does PSM help participants…
- Conditions
- Chronic Pain, Opioid Use Disorder, Opioid Misuse and Addiction
- Trial name
- TREETOP (NCT06855732)
- Testing
- Usual Care, Pain Self-Management
- Where
- 17 sites in United States
- Volunteers
- 204 people
- Sponsor
- University of Pittsburgh
Internet Addiction
Effectiveness of Acceptance and Commitment Therapy in Promoting Mental Health of Emerging Adults With Internet Addiction
Internet addiction, a growing epidemic among young adults, significantly impairs mental health, emotional regulation, and overall well-being.
- Trial name
- NCT07750366
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- Pakistan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National University of Modern Languages
Hand Grip Strength, Quality of Life
Impact of De Quervain's Tenosynovitis on Grip Strength and Quality of Life in Smartphone-Addicted Adolescents
The goal of this Cross Sectional Case Controlled study is to Investigate the effect of de quervain's tenosynovitis on hand grip strength and Quality of life among smartphone addicts' adolescents.
- Trial name
- NCT07758699
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mariam Mohamed Sherif
Obesity & Overweight, Cardiometabolic Health Indicators
Tirzepatide Impact Assessment Study
This study examines how two different weight-loss strategies affect heart and metabolic health, as well as changes at the molecular level in the body.
- Conditions
- Obesity & Overweight, Cardiometabolic Health Indicators, Addiction, Eating Disorders
- Trial name
- TIA (NCT07740291)
- Testing
- GLP-1 Receptor Agonist Therapy, Structured Lifestyle Intervention
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Addiction
Role of Craving in the Transition Across Level of Addiction Severity: A Longitudinal Study.
Substance/Alcohol Use disorders are defined as a loss of control over the use despite harmul consequences, as well as an intense and persistent urge to use, also called craving.
- Trial name
- CARDEMA (NCT07734363)
- Testing
- Observational assessments (EMA and annual DSM-5 evaluations)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University of Bordeaux
Addiction, Opioid
Stagewise Implementation-To-Target- Medications for Addiction Treatment (SITT-MAT)
The purpose of this study is to expand access to medications for opioid use disorder (MOUD) in specialty addiction programs in Washington State.
- Trial name
- SITT-MAT (NCT05343793)
- Testing
- Enhanced Monitoring and Feedback (EMF), NIATx/MAT Academy, NIATx-Internal Facilitation (NIATx-IF)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Stanford University
Smartphone Addiction
The Effects of Smartphone Addiction on Pinch Strength, Muscle Stiffness, and Hand/Wrist Function in Young Adults
Smartphones have become an indispensable part of daily life, and their increasing use has raised concerns about various health effects, including musculoskeletal symptoms.
- Trial name
- NCT06843863
- Testing
- No intervention.
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Nicotine Withdrawal, Nicotine Addiction
Acute Pharmacokinetic and Pharmacodynamic Effects of "Tobacco-Free" Oral Nicotine Pouches in Smokers
The purpose of the present study is to examine the pharmacokinetics and pharmacodynamics of "tobacco-free" oral nicotine pouches, at various doses and flavors, in healthy adult smokers.
- Conditions
- Nicotine Withdrawal, Nicotine Addiction, Drug Effect
- Trial name
- NCT05335915
- Testing
- Nicotine, Cigarette
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Internet Gaming Disorder
Mechanisms and Interventions of Social Reward on Cognitive Control in Internet Gaming Disorder
Internet Gaming Disorder (IGD) involves impaired cognitive control linked to reduced social reward and dACC-DLPFC brain circuit dysfunction. Enhancing social reward may restore this circuit and improve symptoms.
- Trial name
- NCT06957392
- Testing
- Systematic self-help training program for enhancing social reward, general knowledge about Internet Gaming Disorder .
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital of Bengbu Medical University
Internet Gaming Disorder
Virtual Reality Exercise for Young Adults at Risk of Digital Gaming Addiction
Digital game addiction is associated with reduced physical activity, increased sedentary behavior, and adverse physical and psychosocial health outcomes in young adults.
- Trial name
- VR-GAME (NCT07718763)
- Testing
- Traditional Aerobic Exercise, Virtual Reality-Based Aerobic Exercise
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Video Game Addiction, Gaming Disorder
Community-Based Intervention to Reduce Problematic Video Game Use in First-Year Secondary School Students: A Cluster Randomised Controlled Trial
This cluster randomised controlled trial will evaluate whether a community-based, multicomponent intervention can reduce problematic video game use and gaming disorder among first-year secondary school students in Pontevedra…
- Trial name
- AQJ (NCT07357792)
- Testing
- Community-Based Component, Adolescent Mindfulness Component, Adult Mindfulness Component
- Where
- Spain
- Volunteers
- 492 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Posture, Spine
Investigation of Spinal Health and Internet Addiction of Individuals Working Remotely
Low back pain and neck pain are common problems that affect people at certain times in their lives. These people constitute a significant part of the disease burden due to their recurrent complaints.
- Conditions
- Posture, Spine, Internet Addiction, Neck Pain
- Trial name
- NCT05098626
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Substance Abuse, Substance Addiction
The Trans-Led Care Study
This study is testing a new mutual-help group called "the TLC program" for transgender adults who use substances or are recently in recovery.
- Conditions
- Substance Abuse, Substance Addiction, Substance Use Disorder (SUD), Substance Use (Drugs, Alcohol)
- Trial name
- TLC (NCT06880705)
- Testing
- The TLC Program
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Illinois Institute of Technology
Tobacco Use, Tobacco Use Cessation
CONNECT Cancer Survivors With Tobacco Treatment
The purpose of this study is to evaluate the comparative effectiveness of two different informatics-enabled implementation strategies on increasing tobacco treatment and improving smoking cessation rates for cancer control and…
- Conditions
- Tobacco Use, Tobacco Use Cessation, Smoking Cessation, Nicotine Addiction
- Trial name
- NCT07020273
- Testing
- ELEVATE, ELEVATE-S
- Where
- United States
- Volunteers
- 3,543 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Problematic Smartphone Use, Internet Addiction
Digital Technology Use, Digit Ratio, and Handgrip Strength in University Students
This observational cross-sectional study examined associations among second-to-fourth digit ratio, handgrip strength, problematic smartphone-use symptoms, problematic Internet-use symptoms, and self-reported smartphone usage time…
- Conditions
- Problematic Smartphone Use, Internet Addiction, Healthy Volunteers
- Trial name
- DTU-HGS (NCT07694960)
- Where
- Turkey (Türkiye)
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Inonu University