Clinical trials: Addiction Disorders
Anxiety Disorders, Opiate Addiction
Study of Treatment for Opioid Dependence and Anxiety Disorders
Anxiety is highly prevalent among individuals with opioid dependence and confers greater risk for continued opioid use and poor treatment outcomes.
- Trial name
- NCT02252068
- Testing
- I-CBT, IDC
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Mclean Hospital
Alcoholism
Pharmacogenetic Treatments for Alcoholism
Heavy drinking can cause serious health, family, and economic problems. Finding treatments that are effective in decreasing heavy drinking among alcohol-dependent individuals is, therefore, an important scientific and health…
- Trial name
- NCT01591291
- Testing
- Ondansetron + Brief Behavioral Enhancement Treatment
- Where
- 2 sites in United States
- Sponsor
- University of Virginia
Opioid-Induced Hyperalgesia
Hyperalgesia in Methadone-Maintained Patients: Can it be Treated?
Utilizing a double-blind, placebo-controlled design, the proposed work will evaluate the ability of an adjuvant anticonvulsant analgesic to diminish or reverse the opioid-induced hyperalgesia complicating the pain states suffered…
- Trial name
- NCT01210079
- Testing
- Gabapentin;
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, Los Angeles
Breast Feeding, Opioid-Related Disorders
Methadone Levels in Breast Milk of Women Taking Methadone for Opiate Addiction - 2
Methadone is a drug that offers significant therapeutic benefits to opiate dependent women who are pregnant. Currently, it is the treatment of choice for this group of people.
- Trial name
- NCT00218010
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cocaine Addiction
Integrative Meditation (IM) for Cocaine Addiction
Cocaine addiction continues to be a major problem in the U.S. with no FDA-approved pharmaceutical therapy. Finding effective treatment for cocaine addiction has long been a challenge to scientists and clinicians.
- Trial name
- NCT01211418
- Testing
- Integrative Meditation, Supportive Counseling
- Where
- 3 sites in United States
- Volunteers
- 66 people
- Sponsor
- University of Maryland, Baltimore
Opioid Use Disorder, Substance Use Disorder
Neurofeedback During Naturalistic Stimuli to Reduce Craving in Heroin Addiction
Support groups are an important component of addiction treatment, where individuals at more stable stages of their recovery help others by sharing personal experiences.
- Conditions
- Opioid Use Disorder, Substance Use Disorder, Heroin Use Disorder
- Trial name
- NCT07344233
- Testing
- Real-time fMRI Neurofeedback
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Opioid Use Disorders, Opioid-related Disorders
Prevalence and Predictors of Prolonged Post-surgical Opioid Use: a Prospective Observational Cohort Study
Post-surgical opioid prescribing intended for the short-term management of acute pain may lead to long-term opioid use, and its associated harms.
- Conditions
- Opioid Use Disorders, Opioid-related Disorders, Surgery, Pain, Postoperative
- Trial name
- NCT02571400
- Testing
- Continued use of opioid analgesics >90 days post-surgery
- Where
- Australia
- Volunteers
- 1,013 people
- Sponsor
- University of Notre Dame Australia
Internet Gaming Disorder, Internet Addiction
Family Centered Treatment for Problematic Gaming and Excessive Screen Use
The general increase in screen time as a time-consuming leisure activity among children and youth has been a puzzle to the adult world.
- Trial name
- NCT06098807
- Testing
- Family Centered Treatment for Problematic Gaming and Excessive Screen Use
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Region Skane
Substance Use, Substance Use Disorders
Peer-Delivered Behavioral Activation for Methadone Adherence - Pilot Phase
The purpose of this study is to evaluate the feasibility and effectiveness of a peer-led, brief, behavioral intervention to improve adherence to medication for opioid use disorder (MOUD) among low-income, minoritized individuals…
- Conditions
- Substance Use, Substance Use Disorders, Opioid-use Disorder, Peer Delivered
- Trial name
- HEAL Together (NCT04248933)
- Testing
- Peer-Delivered Behavioral Activation (Peer Activate)
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of Maryland, College Park
Stimulant Use Disorder, Substance-related Disorders
Treating Stimulant Addiction With Repetitive Transcranial Magnetic Stimulation
The purpose of this study is to establish a new treatment (repetitive transcranial stimulation (rTMS)) for Veterans with stimulant use disorder (SUD).
- Trial name
- VA-StARTS (NCT04228276)
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Substance Use Disorder (SUD), Mental Health Disorder
Reentry Assist (R-Assist)
This project will aim to develop and pilot test, R-Assist, a mobile health application to support individuals with co-occurring substance use and mental health disorders (COD) in their recovery, who have recently released from a…
- Conditions
- Substance Use Disorder (SUD), Mental Health Disorder, Criminal Recidivism
- Trial name
- R-Assist (NCT06980233)
- Testing
- reentry assistance mobile health app
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Meaningful Measurement, Inc
Internet Addiction Disorder, Health Promotion
The Effect of Health Education on Digital Game Addiction and Health Promotion Behavior in Adolescents
This study aimed to evaluate the effectiveness of a school nurse-led health education program in reducing digital game addiction and improving health-promoting behaviors among adolescents.
- Conditions
- Internet Addiction Disorder, Health Promotion, Digital Game Addiction, Adolescent
- Trial name
- NCT07002515
- Testing
- Health Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Alcoholism
Topiramate Augmenting Strategies for the Treatment of Alcohol Use Disorder
This is a pilot study designed to evaluate the safety, tolerability of Topiramate (TPM) + N-Acetyl Cysteine (NAC) in combination versus Topiramate (TPM) + placebo for the treatment of alcohol use disorder (AUD).
- Trial name
- NCT03120468
- Testing
- Topiramate and N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Nassima Ait-Daoud Tiouririne
Addiction Disorders
Attachment and Substance Use Disorder: An Interventional Study in an Addictology Day Hospital
Introduction: Substance use disorders represent a major public health issue due to their high morbidity and mortality rates. Outpatient care, particularly short-term intensive programs integrating multidisciplinary support and…
- Trial name
- CRAV-ATT (NCT07831135)
- Testing
- attachment-focused therapeutic program, psychoeducation-based intervention (standard care)
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre Hospitalier de Cadillac
Alcohol Addiction, Alcohol Dependence
Qi Gong as a Method of Craving Reduction in Severe Addict Patients
Craving arises in response to an affective tone that is associated with perceptual representations of a sensory object, rather than directly in response to the object.
- Trial name
- QICA (NCT03589118)
- Testing
- Qi Gong sessions
- Where
- 3 sites in France
- Volunteers
- 186 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Opioid-Related Disorders
Assessment of Tramadol as a Treatment for Opioid Addiction
Opioids are one of the most commonly abused drugs among individuals who seek treatment for drug abuse. Thus, it is necessary to develop new treatments for opioid addiction.
- Trial name
- NCT00301210
- Testing
- Tramadol
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Johns Hopkins University
Adolescents, Conduct Disorder
Teenagers, Drug Addiction, and Reward and Impulse Control
Background: The risk for becoming addicted to drugs varies from person to person, even among those who use similar drugs in a similar way.
- Conditions
- Adolescents, Conduct Disorder, Vulnerability to Substance Addicition
- Trial name
- NCT01443949
- Sponsor
- National Institute on Drug Abuse (NIDA)
Alcohol Use Disorder
Does Oxytocin Alter Tolerance to or Motivation for Alcohol
This pilot study is intended to demonstrate feasibility and acquire preliminary data. If successful, this data could support a future project studying the effect of oxytocin on tolerance and alcohol seeking in humans.
- Trial name
- NCT05312008
- Testing
- Intranasal oxytocin
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Indiana University
Substance Use Disorders
Effects of In-Home Addiction Treatment for First Responders
Retrospective analysis to evaluate impact of an in-home addiction treatment program on first responders with substance use disorder.
- Trial name
- NCT03907709
- Testing
- In-Home Addiction Treatment Program
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- In-Home Addiction Treatment Institute, Inc.
Buprenorphine, HIV
Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM)
The purpose of this study is to assess the feasibility, cost and effectiveness of interventions designed to integrate buprenorphine treatment for opioid dependence into HIV primary care in ten HIV care centers in the U.S.
- Conditions
- Buprenorphine, HIV, Drug Abuse, Drug Addiction
- Trial name
- BELIEVE (NCT00798538)
- Testing
- Services will be provided at one site, Services remain dispersed; i.e., not centralized to one-location or provider.
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University