Clinical trials: Adenoma
Pituitary Adenoma
Glycemic Fluctuations in Newly Diagnosed Growth Hormone-Secreting Pituitary Adenoma and Cushing Syndrome Subjects
Glucose fluctuations present not only in patients with diabetes mellitus but also in subjects with normal glucose tolerance or impaired glucose regulation.
- Trial name
- NCT02574793
- Testing
- continuous glucose monitoring
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Huashan Hospital
Colorectal Neoplasms, Colonic Polyp
BowelScope: Accuracy of Detection Using ENdocuff Optimisation of Mucosal Abnormalities
This study aims to assess the effect, if any, on the adenoma detection rate of BowelScope bowel cancer screening flexible sigmoidoscopies by using the Endocuff Vision device.
- Conditions
- Colorectal Neoplasms, Colonic Polyp, Adenoma, Neoplasia GI
- Trial name
- B-ADENOMA (NCT03072472)
- Testing
- Endocuff Vision
- Where
- 16 sites in United Kingdom
- Volunteers
- 3,221 people, healthy volunteers welcome
- Sponsor
- South Tyneside and Sunderland NHS Foundation Trust
Pleural Effusion, Malignant, Ascites, Malignant
Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)
The primary objective of this study, sponsored by Travera Inc. in Massachusetts, is to validate whether the mass response biomarker has potential to predict response of patients to specific therapies or therapeutic combinations…
- Conditions
- Pleural Effusion, Malignant, Ascites, Malignant, Carcinoma, Carcinoma, Hepatocellular
- Trial name
- TraveraRTGx (NCT05461430)
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Travera Inc
Endoscopic Full Thickness Resection (EFTR), Residual /Recurrent Colorectal Lesion
Technical Failure During Colorectal Endoscopic Full Thickness Resection (EFTR): The "Through Thick and Thin" Study
Among advanced resection techniques, endoscopic full thickness resection (EFTR) allows closure and full-thickness resection by the use of the non-exposed full thickness resection device (FTRD).
- Conditions
- Endoscopic Full Thickness Resection (EFTR), Residual /Recurrent Colorectal Lesion, Full-thickness Resection Device (FTRD), Colorectal Adenoma
- Trial name
- NCT05913453
- Where
- Italy
- Volunteers
- 77 people
- Sponsor
- Azienda Unità Sanitaria Locale della Romagna
Gardner Syndrome, Colorectal Carcinoma
A Cohort Study of Patients Treated With Brachytherapy for Selected Desmoid Patients in Gardner Syndrome
The purpose of this study is to assess the long-term outcome in a cohort of Gardner-Syndrome patients receiving prophylaxis and treatment for intestinal and non-intestinal tumors.
- Conditions
- Gardner Syndrome, Colorectal Carcinoma, Desmoid Tumor
- Trial name
- NCT01286662
- Volunteers
- 105 people
- Sponsor
- Triemli Hospital
Malignant Mesothelioma
Palliative Therapy With or Without Chemotherapy in Treating Patients With Malignant Mesothelioma
RATIONALE: Palliative therapy may help patients with advanced cancer live more comfortably. It is not yet known if palliative therapy is more effective with or without chemotherapy in treating patients who have malignant…
- Trial name
- NCT00030459
- Testing
- cisplatin, mitomycin C, vinblastine sulfate
- Where
- 9 sites in United Kingdom
- Sponsor
- British Thoracic Society
Colorectal Adenoma, Colorectal Polyp
EndoRings Colonoscopy vs Standard Colonoscopy
The study aims to compare the results between a standard colonoscopy to a colonoscopy with an attachment on the distal end of the colonoscope.
- Conditions
- Colorectal Adenoma, Colorectal Polyp, Colon Cancer
- Trial name
- NCT03418662
- Testing
- EndoRings device
- Where
- United States
- Volunteers
- 592 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cushing's Syndrome
A Study of the Efficacy and Safety of CORLUX in the Treatment of Endogenous Cushing's Syndrome
Patients will receive Corlux (mifepristone) daily for up to 24 weeks. Assessments of the signs and symptoms of Cushing's syndrome will be obtained.
- Trial name
- SEISMIC (NCT00569582)
- Testing
- mifepristone
- Where
- 17 sites in United States
- Volunteers
- 50 people
- Sponsor
- Corcept Therapeutics
Colon Cancer
Multi Parametric Test Predicting the Risk of Colorectal Neoplasia Recurrence
This project is dedicated to identify the patients with possible higher risk of adenoma recurrence who should have follow-up colonoscopy in yearly interval.
- Trial name
- NCT03434925
- Testing
- Multi-targeted next generation sequencing
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- Military University Hospital, Prague
Breast Cancer, Colorectal Cancer
Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid Tumors
RATIONALE: Sorafenib and pemetrexed may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Sorafenib may also stop the growth of tumor cells by blocking blood flow to the tumor.
- Conditions
- Breast Cancer, Colorectal Cancer, Head and Neck Cancer, Lung Cancer
- Trial name
- NCT00703638
- Testing
- cisplatin, pemetrexed disodium, sorafenib
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Adenomatous Polyps
Safety and Efficacy of Endocuff-assisted Colonoscopy for Adenoma Detection.
This study investigated the impact of Endocuff-assisted colonoscopy on the adenoma detection rate at colonoscopy. This study involved patients undergoing elective screening or surveillance colonoscopy.
- Trial name
- NCT02374515
- Testing
- EndoCuff-assisted colonoscopy, Standard Colonoscopy
- Where
- Italy
- Volunteers
- 275 people
- Sponsor
- University of Naples
Hyperaldosteronism, Hypertension
Water and Electrolytes Content in HYpertension (WHYSKI) in the SKIn
WHYSKI is a prospective within-patient observational clinical study designed to test the hypothesis that alterations of Na+, K+, water, and the lympho-angiogenetic transcription factor Tonicity Enhancing Binding Protein (TonEBP)…
- Conditions
- Hyperaldosteronism, Hypertension, Aldosterone-producing Adenoma, Aldosteronism
- Trial name
- WHYSKI (NCT06090617)
- Testing
- Skin Biopsy, Video-laparoscopic adrenalectomy
- Where
- Italy
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Mesothelioma, Peritoneal Mesothelioma
A Study of Immunotherapy Drugs Nivolumab and Ipilimumab in Patients w/Resectable Malignant Peritoneal Mesothelioma
This study is for individuals who have peritoneal mesothelioma, a cancer of the lining of your abdominal wall and organs (the peritoneum).
- Trial name
- NCT05041062
- Testing
- Nivolumab, Ipilimumab
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Chicago
Neoplasms, Colorectal
Green Tea Extracts for the Prevention of Colorectal Adenomas and Colorectal Cancer
Experimental studies have shown the chemopreventive properties of green tea extract (GTE) on colorectal cancer. And colorectal adenomas are precursors to colorectal cancers.
- Trial name
- NCT02321969
- Testing
- GTE (green tea extract)
- Volunteers
- 176 people
- Sponsor
- Seoul National University Hospital
Duodenal Adenomas
Cold Snare Endoscopic Resection for Duodenal Adenomas
Non-ampullary sporadic duodenal adenomas (SDA) are rare lesions, incidentally discovered in up to only 5% of patients during routine endoscopy.
- Trial name
- COLD SNARE (NCT04783961)
- Testing
- Cold snare endoscopic resection
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Istituto Clinico Humanitas
Adenoma, Bile Duct
Destruction of Residual Endo-biliary Dysplastic Buds After Endoscopic Ampullectomy
The purpose of the study is to assess the efficacy and morbidity of biliairy radiofrequency ablation for the treatment of dysplastic endobiliairy residual lesions (low-grade dysplasia or high-grade dysplasia) after endoscopic…
- Trial name
- endoHPB (NCT02825524)
- Testing
- Habib™ EndoHBP
- Volunteers
- 20 people
- Sponsor
- Hôpital Cochin
Malignant Mesothelioma
Gemcitabine and Epirubicin in Treating Patients With Malignant Mesothelioma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00017186
- Testing
- epirubicin hydrochloride, gemcitabine hydrochloride
- Where
- 24 sites in United States
- Volunteers
- 69 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Colorectal Cancer Screening
Comparison of Transparent Retractable Extension Device and Narrow Band Imaging on Colorectal Adenoma Detection
The investigators previously reported that colonoscopy with a transparent retractable extension (TRE) device improved the adenoma detection rate without affecting intubation and withdrawal times.
- Trial name
- NCT00765180
- Testing
- TRE vs. NBI
- Where
- Japan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Showa Inan General Hospital
Prostatic Hyperplasia, Benign, Prostatic Adenoma
Observational Study to Compare Two Prostate Laser Enucleation Techniques in Terms of Urinary Incontinence
Benign prostatic hypertrophy or prostatic adenoma is a benign tumour that develops in the central part of the prostate. Prostatic adenoma can result in the progressive appearance of a difficulty in evacuating the bladder or…
- Trial name
- ENUPLASMHO (NCT05157724)
- Testing
- PLASMA
- Where
- France
- Sponsor
- Elsan
Mesothelioma
Cisplatin, Pemetrexed, and Imatinib Mesylate in Malignant Mesothelioma
Primary Objective: To determine the maximum tolerated dose of the combination of cisplatin, imatinib mesylate, and pemetrexed in metastatic malignant mesothelioma.
- Trial name
- NCT00402766
- Testing
- Cisplatin, Imatinib Mesylate, Pemetrexed
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- M.D. Anderson Cancer Center