Clinical trials: Adenoma Colon Polyp
Colonic Polyps
Detection of Colorectal Adenoma by Optical Enhancement Technology vs. High-Definition Colonoscopy
Optical Enhancement Technology might be superior to the conventional HD-WL in detecting colorectal adenomas
- Trial name
- NCT02865382
- Testing
- white light was used for colonoscopy withdrawal, OE mode was used for colonoscopy withdrawal
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Yanqing Li
Adenoma, Colo-rectal Cancer
Clinical Value of G-EYE Colonoscopy in Daily Practice for Adenoma Detection and Time for Polyp Removal
Colonoscopy parameters will be compared before the introduction of the G-EYE endoscope and after the introduction of the G-EYE endoscope
- Trial name
- NCT04767971
- Testing
- Standard Colonoscopy, G-EYE Colonoscopy
- Where
- Germany
- Volunteers
- 2,795 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Colon Adenoma, Colonoscopy
Water Exchange Colonoscopy With Artificial Intelligence-assisted Detection
The goal of this clinical trial is to compare the detected adenoma per colonoscopy (APC) in participants undergoing screening, surveillance, and positive fecal immunochemical test (FIT) or guaiac fecal occult blood test (gFOBT).
- Conditions
- Colon Adenoma, Colonoscopy, Colon Polyp
- Trial name
- NCT06173258
- Testing
- Water exchange alone, Water exchange plus Artificial Intelligence (AI)
- Where
- 2 sites in Italy, Taiwan
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Evergreen General Hospital, Taiwan
Colonic Polyps
Efficacy of Segmental Examination Twice of the Proximal Colon on Adenoma Detection
Segmental examination twice of the proximal colon might be helpful to increase adenoma detection rate (ADR).
- Trial name
- NCT02581475
- Testing
- Extending withdrawal time in the proximal colon, Segmental examination twice of the proximal colon
- Where
- China
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Yanqing Li
Colorectal Cancer, Adenoma Colon
Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease Detection
This is an multicenter study that will test the diagnostic accuracy of a blood test (i.e., a liquid biopsy) for the diagnosis of colorectal cancer (CRC), advanced adenomas (AAs), as well as Lynch-syndrome associated cancers.
- Conditions
- Colorectal Cancer, Adenoma Colon, Adenoma Colon Polyp, Colon Adenoma
- Trial name
- BEACON (NCT07450612)
- Testing
- BEACON
- Where
- 4 sites in Italy
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- San Raffaele University
Tuberculosis, Gastric Cancer
Volatiles in Breath and Headspace Analysis - Diagnostic Markers
Detection of Volatile Organic Compounds (VOC) directly from tissue by headspace analysis (skin, surgery material, other tissue) and exhaled breath is feasible using affordable user-friendly novel nano-chemo sensors that can…
- Conditions
- Tuberculosis, Gastric Cancer, Peptic Ulcer, Atrophic Gastritis
- Trial name
- Volatolome (NCT03228095)
- Testing
- VOC detection in breath and in skin headspace, Breath sampling, Upper endoscopy with biopsies
- Where
- Latvia
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Latvia
Colorectal Cancer, Colorectal Adenoma
Comparison of Expression of Carcinogenesis-related Molecular Markers in the Patients With Colon Cancer and Polyp
A study of carcinogenesis-related molecular markers in the patients with colorectal cancer and colorectal adenoma.
- Trial name
- NCT05638542
- Where
- South Korea
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Colonic Polyp, Colonic Diseases
Optical Polyp Testing for In Vivo Classification
Small growths detected in the colon (polyps) during a colonoscopy may or may not have the potential to develop into cancer. However, since visual inspection alone cannot separate all potentially harmful polyps from harmless ones…
- Conditions
- Colonic Polyp, Colonic Diseases, Colonic Neoplasms, Colonic Adenoma
- Trial name
- OPTIC (NCT03139942)
- Testing
- Optical spectral reflectance and autofluorescence imaging
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Colorectal Cancer, Colon Polyps
Prevalence and Topography of Adenomas in 40-49 Year Old Patients With a Family History of Colon Cancer
Conflicting guideline recommendations for screening colonoscopy result due to scant data upon which to develop appropriate recommendations.
- Conditions
- Colorectal Cancer, Colon Polyps, Adenomatous Polyp of Colon
- Trial name
- NCT02289053
- Where
- 6 sites in United States
- Volunteers
- 1,623 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Adenoma Colon, Serrated Polyp
Cold EMR Vs Standard EMR for the Treatment of Large Nonpedunculated Homogeneous Colorectal Lesions
This study compares the effectiveness in complete resection (absence of recurrence at 6 months) the two different techniques for performing endoscopic mucosal resection (EMR) of nonpedunculated homogeneous colorectal lesions >20mm
- Conditions
- Adenoma Colon, Serrated Polyp, Serrated Adenoma, Colorectal Neoplasms
- Trial name
- NCT04418843
- Testing
- Standard Endoscopic Mucosal Resection, Cold Snare Endoscopic Mucosal Resection
- Where
- Spain
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Oscar Nogales
Colorectal Cancer Screening, Colon Polyps and Adenomas
Artificial Intelligence (AI) Technology May Help Patients to Understand Bowel Preparation Better Before They go for Colonoscopy.This Study Attempts to Leverage AI Chatbot in Counselling Patients to Improve Bowel Cleanliness, Reduce Anxiety as Well as Increase Procedural Satisfaction
Traditional pre-colonoscopy counselling requires significant time from healthcare workers to explain procedures, limiting efficiency and patient turnover.
- Conditions
- Colorectal Cancer Screening, Colon Polyps and Adenomas, Bowel Preparation Quality, Artificial Intelligence (AI)
- Trial name
- NCT06905782
- Testing
- AI chatbot study arm, Traditional counselling study arm
- Where
- Malaysia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Adenoma, Polyps
Prospective Trial to Compare the Clinical Efficiency of G-EYE™ HD Colonoscopy With Standard HD Colonoscopy
The purpose of this study is to compare the adenoma detection rate of G-EYE™ high definition colonoscopy with that of standard high definition colonoscopy
- Conditions
- Adenoma, Polyps, Colorectal Cancer
- Trial name
- NCT01917513
- Testing
- G-EYE™ colonoscopy, Standard Colonoscopy
- Where
- 15 sites in United States, Denmark and 6 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Colon Adenoma, Colon Polyp
Artificial Intelligence-assisted Colonoscopy on Detection of Missed Proximal Lesions
This is a prospective multi-center randomized study is to determine whether the use of artificial intelligence (AI)-assistance could reduce the miss rates of polyps and adenomas in the proximal colon during tandem examination
- Trial name
- NCT04294355
- Testing
- Artificial intelligence-Assisted colonoscopy, Conventional colonoscopy
- Where
- 3 sites in China, Singapore and 1 more
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Colonic Polyps
GENESIS: Genetic Biopsy for Prediction of Surveillance Intervals After Endoscopic Resection of Colonic Polyps
Colorectal cancer ist the 2nd most leading cancer among men and women in germany. Screening colonoscopy has the potential to detect premalignant lesions.
- Trial name
- GENESIS (NCT02595645)
- Testing
- Polypectomy and NGS
- Where
- 4 sites in Austria, Germany
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Colorectal Neoplasms, Colorectal Cancer
A Study Comparing Standard and AI-Assisted Colonoscopies for Detecting and Characterizing Colorectal Lesions in Adults Aged 50-74 Undergoing Cancer Screening
The goal of this clinical trial is to determine whether using artificial intelligence (AI) can improve the detection and characterization of abnormal growths (polyps) during colonoscopy in adults aged 50 to 74 years who are…
- Conditions
- Colorectal Neoplasms, Colorectal Cancer, Adenoma Colon Polyp
- Trial name
- NCT07125300
- Testing
- Artificial Intelligence-Assisted Colonoscopy
- Where
- Spain
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Javier Santos Fernández
Colorectal Cancer, Polyp
Performance Evaluation of the NaviAid™ G-Eye System
The purpose of this study is to compare the additional diagnostic yield obtained by performing NaviAid™ G-Eye procedure vs. the diagnostic yield obtained by performing standard colonoscopy procedure.
- Conditions
- Colorectal Cancer, Polyp, Adenoma
- Trial name
- NCT01552200
- Testing
- Group A-Standard Colonoscopy, then NaviAid™ G-Eye procedure, Group B-NaviAid™ G-Eye procedure, then Standard Colonoscopy
- Where
- 4 sites in Germany, Israel
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Colorectal Cancer, Colon Cancer
Pilot Study of Colon Cancer Screening Tests
Colon cancer is the second leading cause of cancer death in North America. These deaths are preventable with proper screening. Fecal occult blood testing, virtual colonoscopy, and standard (optical) colonoscopy are all options…
- Conditions
- Colorectal Cancer, Colon Cancer, Adenomatous Polyps
- Trial name
- NCT00865527
- Testing
- Fecal occult blood test, Virtual colonoscopy, Optical colonoscopy
- Where
- Canada
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Colonic Polyps
Effect of Single Colonoscopy on Colorectal Adenomas Detection
Individualized colonoscopy withdrawal time is determined based on the different grade of physician experience and quality of bowel preparation.
- Trial name
- NCT02693886
- Testing
- doctor experience
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Wuxi People's Hospital
Diminutive Colon Polyp, Adenomatous Polyp
Comparative Study of Postprocessing Imaging Systems for Diminutive Colonic Polyps
Several novel imaging technologies are currently used for detection and differentiation of colonic polyps during colonoscopy, such as NBI (Olympus), FICE (Fujinon), and i-Scan (Pentax).
- Conditions
- Diminutive Colon Polyp, Adenomatous Polyp, Hyperplastic Polyp, Colonoscopy
- Trial name
- NCT01133041
- Testing
- Observation using NBI system, Observation using i-Scan system
- Where
- South Korea
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Soon Chun Hyang University
Screening Colonoscopy, Surveillance Colonoscopy
A Study to Evaluate the Safety and Efficacy of the Use of ME-APDS During Colonoscopy
ME-APDS is a device (software-based with hardware) developed by Magentiq Eye LTD and intended to support the decision of the endoscopist on polyps which appear in the colonoscopy video during the colonoscopy procedure.
- Trial name
- NCT04640792
- Testing
- Screening or Surveillance Conventionall colonoscopy
- Where
- 11 sites in United States, Germany and 2 more
- Volunteers
- 952 people, healthy volunteers welcome
- Sponsor
- Magentiq Eye LTD