Clinical trials: Adherence, Patient
Childhood Cancer, Survivorship
A Multilevel Intervention to Improve Adherence to Childhood Cancer Survivorship
More than 80% of childhood cancer survivors develop serious or life-threatening late effects after cancer therapy, but <20% receive recommended survivorship care offered at cancer center survivorship clinics.
- Conditions
- Childhood Cancer, Survivorship, Health Care Utilization, Health Knowledge, Attitudes, Practice
- Trial name
- BRIDGES (NCT05448560)
- Testing
- Multi-level Intervention of shared model of survivorship care, Comparison Group
- Where
- 4 sites in United States
- Volunteers
- 240 people
- Sponsor
- Georgetown University
Mild Cognitive Impairment, Adherence, Patient
MI-CBT Adherence Program for Lifestyle Interventions in Older Adults
Objective 1: Assess feasibility and acceptability of all protocol components of a pilot trial testing a 6-week telehealth Mediterranean ketogenic nutrition adherence (KNA) program using motivational interviewing and cognitive…
- Conditions
- Mild Cognitive Impairment, Adherence, Patient, Ketosis
- Trial name
- MI-CBT KNAP (NCT04817176)
- Testing
- Motivational Interviewing-Cognitive Behavioral Therapy Ketogenic Nutrition Adherence Program, Ketogenic Nutrition Program
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Florida State University
Lung Cancer, Adherence, Patient
Increasing Adherence to Lung Cancer Screening
Investigators are conducting a pragmatic randomized trial testing the effectiveness of patient and clinician nudge strategies on adherence to lung cancer screening (LCS) \& diagnostic follow-up across eligible primary care…
- Trial name
- NCT05832008
- Testing
- Patient Nudge, Clinician Nudge
- Where
- United States
- Volunteers
- 825 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Medication Adherence
Smart About Meds (SAM) RCT
Introduction: Almost half of patients discharged from hospital are re-admitted or return to the emergency department (ED) within 90 days.
- Trial name
- NCT05371548
- Testing
- SAM mobile application
- Where
- Canada
- Volunteers
- 3,250 people
- Sponsor
- Robyn Tamblyn
Cataract, Surgery
Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population
The current postoperative cataract surgery eye drop regimen used at Zuckerberg San Francisco General Hospital (ZSFG) is a significant burden for its patient population, contributing to high rates of non-adherence and the…
- Conditions
- Cataract, Surgery, Compliance, Patient, Compliance, Medication
- Trial name
- NCT05157113
- Testing
- Dropless Regimen, Standard Regimen
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of California, San Francisco
Violence, Domestic, HIV
1MoreStep: An Intervention to Increase HIV Care Engagement and Reduce Intimate Partner Violence Among Black Women Living With HIV
This study tests a 5-session cognitive behavioral approach program (herein referred to as the 1MoreStep intervention) to train Black women living with HIV (BWLWHI) and exposed to intimate partner violence (IPV) in the past 2…
- Conditions
- Violence, Domestic, HIV, Stigma, Social, Engagement, Patient
- Trial name
- NCT05608421
- Testing
- 1MoreStep, 1MoreStepControl
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Johns Hopkins University
Chatbot-Based Training, Hemodialysis
DialysisBot: AI Chatbot for Hemodialysis Self-Management
End-stage kidney disease requiring hemodialysis is a chronic condition with substantial clinical, functional, and psychosocial burden.
- Conditions
- Chatbot-Based Training, Hemodialysis, Self-management
- Trial name
- NCT07830810
- Testing
- DialysisBot
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Rome Tor Vergata
Breast Cancer, Breast Neoplasms
Integrating Biological, Clinical, and Behavioral Factors to Improve Breast Cancer Outcomes - Carolina Breast Cancer Study
Phase 4 of the Carolina Breast Cancer Study (CBCS4) builds on prior phases that examined molecular and epidemiologic differences in breast cancer types and outcomes.
- Trial name
- NCT07214610
- Testing
- Structured behavioral intervention
- Where
- United States
- Volunteers
- 3,300 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Noninvasive Ventilation, Child, Only
Custom Non-invasive Ventilation Masks in Children
One significant challenge to non-invasive ventilation (NIV) use in children is finding masks to fit a wide range of growing shapes and sizes.
- Conditions
- Noninvasive Ventilation, Child, Only, Adherence, Patient
- Trial name
- NCT05336136
- Testing
- Custom mask, Current commercial mask
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Alberta
Therapeutic Adherence, Nurse-Patient Relations
The Effect of Therapeutic Touch on Sleep and Anxiety
The aim of this study is to determine the effect of the therapeutic touch applied to the sleep patterns of individuals aged 65-85 years with chronic diseases who are treated in the Neurology Intensive Care Unit of Ankara City…
- Conditions
- Therapeutic Adherence, Nurse-Patient Relations, Sleep Disorder
- Trial name
- NCT05363787
- Testing
- therapeutic touch
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- KTO Karatay University
Transplant;Failure,Kidney, Transplant; Failure, Liver
Leveraging Technology to Improve Medication Adherence in Youth With Kidney or Liver Transplant
Can the investigators create an effective way to improve adherence to immunosuppressant medication and reduce rejection, graft loss, and death in adolescents and young adults who have undergone kidney or liver transplantation?…
- Conditions
- Transplant;Failure,Kidney, Transplant; Failure, Liver, Adherence, Medication, Adherence, Patient
- Trial name
- NCT05613010
- Testing
- mHealth Messaging Intervention Group
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Johns Hopkins University
Hiv, AIDS
ALHIV Smartphone Game Study
This is a cluster-randomized controlled trial that aims to conduct comprehensive feasibility testing of a smartphone game in a sample of 120 adolescents living with HIV (ALHIV) ages 15-21 in Kisumu, Kenya, to determine whether…
- Conditions
- Hiv, AIDS, Adolescent Behavior, Treatment Compliance
- Trial name
- NCT06913660
- Testing
- MyGoals, Standard of care
- Where
- Kenya
- Volunteers
- 120 people
- Sponsor
- Emory University
Glaucoma Medication Adherence, Glaucoma Patients
Eye Patient Adherence and Compliance Study
This study looks at ways to help people with glaucoma take their eye drops regularly and attend their clinic appointments. Each participant will be asked about the main challenges they face, such as forgetfulness, difficulty…
- Trial name
- EYE-PACIP (NCT07793474)
- Testing
- Eye Droppers, Eye Educate, Eye Coordinate
- Where
- Canada
- Volunteers
- 189 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Health Knowledge, Attitudes, Practice, Vaccine-Preventable Diseases
Culturally Tailored HPV Psychoeducational Multimedia Intervention
Community members ages 18 - 45 years old from the El Paso, Texas, U.S.-Mexico Border Region will be recruited to compare psychoeducational multimedia interventions focused on the human papillomavirus (HPV).
- Conditions
- Health Knowledge, Attitudes, Practice, Vaccine-Preventable Diseases, Intention, Adherence, Patient
- Trial name
- NCT06098690
- Testing
- Culturally Tailored Multimedia Psychoeducational HPV Intervention, General HPV Multimedia Psychoeducational Control Group
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Hiv, Transmission Vertical
Enhanced Mentor Mother Strategy for Pregnant and Postpartum Women Living With HIV
Mentor Mothers (MMs) are peer supporters who help pregnant and postpartum women living with HIV (WLHIV) as they receive prevention of mother-to-child transmission of HIV (PMTCT) services in resource-limited settings like Kenya.
- Conditions
- Hiv, Transmission Vertical, Viremia, Adherence, Treatment
- Trial name
- PIE-eMMs (NCT06999928)
- Testing
- Enhanced Mentor Mother Strategy
- Where
- Kenya
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Indiana University
Adherence, Patient
Identification of Surrogate Blood and/or Urine Biomarker for Immulina TM (Trademark) in Normal Humans
This is a pilot study for identifying plasma and/or urine-derived adherence/surrogate biomarker candidates for verifying Immulina™ ingestion by human volunteers (collected before and after consumption of Immulina™, a natural…
- Trial name
- NCT05556967
- Testing
- Immulina
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
HIV Infection
Tenofovir, Emtricitabine and Efavirenz Late Switch to a Single Pill: Patients' Opinion Survey
The purpose of this study is to assess adherence, tolerability and satisfaction of each eligible HIV subjects switching from a two- or three-pill tenofovir-emtricitabine-efavirenz (TDF-FTC-EFV) to a one-pill TDF-FTC-EFV treatment.
- Trial name
- NCT01322932
- Where
- Switzerland
- Volunteers
- 95 people
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Cancer
Collaborative Seamless Care in Oncology : Measure and Reinforce Safety and Adherence to Oral Cancer Treatment
The purpose of this study is to implement a support interdisciplinary program(oncologists, pharmacists, physicians, nurses, leagues against cancer) of medication adherence to oral oncology treatments.
- Trial name
- NCT01370980
- Where
- Switzerland
- Volunteers
- 43 people
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Heart Transplant Rejection, Immune Suppression
Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients
We will conduct a two-group randomized controlled trial to examine the eMocha DOT intervention with pediatric HT recipients.In this population, medication nonadherence remains a primary cause of late acute rejection (LAR)…
- Conditions
- Heart Transplant Rejection, Immune Suppression, Pediatric Heart Transplant, Medication Nonadherence
- Trial name
- NCT05732779
- Testing
- DOT intervention
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Florida
Resistant Hypertension, Medication Adherence
Heart Rate Variability and Medication Adherence in Resistant Hypertension
This single-center, cross-sectional observational study examines the relationship between adherence to antihypertensive therapy - verified objectively by therapeutic drug monitoring (TDM) - and heart rate variability (HRV) in…
- Conditions
- Resistant Hypertension, Medication Adherence, Autonomic Nervous System
- Trial name
- HRV-HYP-1 (NCT07707583)
- Testing
- Heart rate variability recording (Polar H10) ·, Therapeutic drug monitoring (antihypertensive drug levels), Questionnaires (MARS-CZ, PHQ-9, SF-36, IPAQ)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.