Clinical trials: Adhesion
Healthy
Bioequivalence of Two Transdermal Clonidine Administrations in Healthy Volunteers
To establish the bioequivalence and adhesion properties of transdermal clonidine prepared with Oppanol® brands of polyisobutylene (PIB) vs.
- Trial name
- NCT02096744
- Testing
- Catapres-TTS-1, Intervention 1: Catapres-TTS-3, Intervention 2: Catapres-TTS-3
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Biting Forces, Bone; Change, Diabetic (Manifestation)
Evaluation Of Marginal Bone Height Changes And Biting Force In Screw Retained Implant Prostheses Using Reinforced Resin Vs Monolithic Zirconium
This studies aims to compare the behavior of recently introduced resin reinforces compared to monolithic zirconia
- Conditions
- Biting Forces, Bone; Change, Diabetic (Manifestation), Color Stability, Disorder of Soft Tissue
- Trial name
- NCT07007572
- Testing
- Digitally-fabricated implant supported supra-structure fabricated from reinforced resin, Digitally-fabricated implant supported supra-structure fabricated from monolithic zirconia
- Where
- 2 sites in Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Cairo University
Spinal Cord Tumors
MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment
In spinal cord tumors requiring surgical intervention, the resection difficulty is determined by two significant factors: tumor stiffness and adhesion to surrounding tissue.
- Trial name
- NCT05957679
- Testing
- Magnetic Resonance Elastography, Assessment and Recording
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Malaria
Collection of Biological Material From Pregnant Women in a Malarial Region
Background: Malaria is a disease caused by a parasite that infects the blood. It affects millions of people every year and frequently harms or kills pregnant woman and infants.
- Trial name
- NCT01862783
- Where
- Uganda
- Volunteers
- 1,270 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Restoration of Posterior Teeth
Clinical Performance of Different Resin Cements
The clinical performance of different resin cements in adhesion of hybrid ceramic inlay and onlay restorations produced with CAD/CAM will be evaluated and compared.
- Trial name
- NCT04694690
- Testing
- Self adhesive resin cement, Resin cement
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Bioequivalence Study in Healthy Subjects
Rivastigmine Transdermal Patches Bioequivalence and Adhesion Assessment
This study evaluates the bioequivalence and adhesion performance of a test rivastigmine transdermal patch compared with the reference product, Exelon® Patch 10 (9.5 mg/24 h), in healthy adult volunteers of both sexes under…
- Trial name
- NCT07464340
- Testing
- Rivastigmine TDS 9,5 mg/24 h, Exelon® 9.5 mg/24 h
- Where
- Brazil
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Zodiac Produtos Farmaceuticos S.A.
Healthy
Effect of Mental Stress on Platelet Function in Healthy Subject
Psychological stress is an independent cardiovascular risk factor. Activation of platelets plays an important role in atherosclerosis development and it could one of the mechanisms linking psychological stress and cardiovascular…
- Trial name
- NCT00621738
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hyperemesis; Gravidarum, With Dehydration
Endothelial Dysfunction in Hyperemesis Gravidarum
The purpose of the study is to determine serum inflammatory adhesion molecules levels in hyperemesis gravidarum
- Trial name
- NCT02989337
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Intrauterine Adhesion
Autologous Platelet-Rich Plasma in the Management of Asherman Syndrome
The aim of the study is to find out the benefit of the platelet-rich plasma in preventing reformation of intrauterine adhesions after adhesiolysis in cases of Asherman syndrome
- Trial name
- NCT04308811
- Testing
- platelet rich plasma, amniotic membrane graft group, Intrauterine balloon
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Obesity, Lung Functions
The Effect of CLA on Obesity, Lung Functions, Lipid Profile and Inflammation in Women With BMI≥25
Conjugated linoleic acid or CLA, is one of the food supplements that could be found in meat, fats, and dairy products of ruminants which has been fed grass not on grains.
- Conditions
- Obesity, Lung Functions, Inflammation, Lipid Disorder
- Trial name
- NCT04641494
- Testing
- Conjugated linoleic acid, High oleic acid safflower oil capsules
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Chester
Arteriosclerosis, Stress, Psychological
The Effect of Beta-Blockers and Aspirin on Hemostasis and Endothelial Function After Acute Mental Stress
This randomized double-blinded controlled trial uses a factorial design to investigate whether application of beta-blockers (inderal 80 mg) or aspirin (100 mg) or a combination thereof has an effect on the activation of the…
- Trial name
- NCT00174902
- Testing
- inderal (drug), acetylsalicylic acid (drug)
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Healthy
Evaluation of Adhesion and Dermal Tolerability of EMSAM
Examine adhesive and dermal tolerability of EMSAm 6mg/24hr and 12mg/24hr in healthy elderly and non-elderly subjects.
- Trial name
- NCT00531596
- Testing
- EMSAM (Selegiline Transdermal System) 6mg/24Hr, EMSAM (Selegiline Transdermal System) 9mg/24Hr, EMSAM (Selegiline Transdermal System) 12mg/24hr
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Somerset Pharmaceuticals
Healthy
A Comparative Study to Evaluate Two Air-Activated Adhesive Backed Heat Patches
A disposable, air-activated, adhesive backed heat patch is being evaluated. Study terminated -O subjects.
- Trial name
- NCT02080143
- Testing
- Thermal Adhesion Patch
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chattem, Inc.
Hypercholesterolemia, Postmenopause
Vascular and Metabolic Effects of Hormone Therapy Combined With L-Arginine in Postmenopausal Women
Estrogen therapy has been associated with reduced risk of coronary heart disease events in observational studies of postmenopausal women.
- Trial name
- NCT00001752
- Testing
- L-arginine, Estrogen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Denture Stomatitis, Wear of Denture Teeth
Novel Coating to Minimize Bacterial Adhesions and Tooth Wear in Denture Acrylic
This study evaluates the effect of coatings on bacterial adhesion on denture acrylic and the wear of denture teeth.
- Trial name
- NCT02834832
- Testing
- PECVD coating
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Florida
Visual Acuity
Ex-vivo Adhesion of Bacteria to Different Contact Lens Materials
This is a single-site, 4-visit, contralateral, dispensing, open-label, randomized study. Each eligible subject will be randomized into one of two sequence groups to wear two lens types contralaterally (Test on the right eye and…
- Trial name
- NCT04108286
- Testing
- 1-DAY ACUVUE MOIST, DAILIES AQUA COMFORT PLUS
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myocardial Infarction, Chronic Periodontitis
The Effect of Periodontal Therapy in Chronic Periodontitis Patients With and Without Acute Myocardial Infarction
The aim of this study was to evaluate the effects of periodontal treatment on gingival crevicular fluid (GCF) levels of Neopterin(N) and vascular cell adhesion molecule (VCAM-1) in chronic periodontitis(CP) patients with acute…
- Trial name
- NCT03005886
- Testing
- Periodontal examination, GCF sampling, phase I therapy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Tissue Adhesions
A Randomized Multi-centre Study to Assess the Safety and Manageability of a Laparoscopic Adhesion Barrier in Women Undergoing Gynecologic Laparoscopic Surgery Followed by Second Look Laparoscopy
The purpose of this study is to obtain data on the safety and manageability of applying LABS™ to the uterus and other areas of surgical trauma in the pelvis and abdomen following laparoscopic gynaecologic surgery.
- Trial name
- LABS-1 (NCT02260115)
- Testing
- LABS™, Surgical Control
- Where
- 4 sites in Germany, Greece
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Actamax Surgical Materials LLC
Obstetric Complication, Muscle Injury
Does Rectus Re-approximation Cause Adhesion After Cesarean Section?
Rectus re-approximation and periton closure are not the obligatory steps during cesarean section. These steps are due to surgeon's preference.
- Trial name
- NCT04483986
- Testing
- Rectus muscle re-approximation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Giresun University
Adhesions Pelvic, Adhesion; Uterus
Prediction of Vesicouterine Adhesions by Transvaginal Sonographic Sliding Sign Technique: a Validation Study
The aim of this study is to evaluate the predictive value of the real-time dynamic TVS sliding sign for vesicouterine pouch adhesions in women and to test the inter- and intraobserver agreement of this new technique.
- Conditions
- Adhesions Pelvic, Adhesion; Uterus, Adhesion; Bladder
- Trial name
- NCT05862155
- Where
- Netherlands
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc