Clinical trials: Adipose-derived Stem Cells
Atrophic Scar
Safety and Tolerability of Autologous Adipose-derived Mesenchymal Stem Cells Therapy in Adults With Atrophic Scars
The purpose of this clinical trial was to evaluate the safety and tolerability for 12 weeks after one dose of TRTP-101 in adults with atrophic scars.
- Trial name
- NCT06210919
- Testing
- TRTP-101
- Where
- South Korea
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- CellinCells
Gastrointestinal Fistula
Conservative Treatment of Gastrointestinal Fistulas by Endoscopic Injection of tSVFem
Gastrointestinal (GI) fistula is a complex condition with high mortality and requiring a multidisciplinary management. The aim of this study is to exploit the regenerative-tissue capacities of autologous emulsified adipose…
- Trial name
- tSVFem (NCT04670276)
- Testing
- injection of emulsified adipose tissue stromal vascular fraction
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Supraspinatus Tear
Mesenchymal Stem Cells and Amniotic Membrane Composite for Supraspinatus Tendon Repair Augmentation
This is a non-randomized clinical trial conducted in a single tertiary hospital which investigates the efficacy of allogeneic adipose-derived mesenchymal stem cells and human amniotic membrane (AAdMSC-HAM) composite for…
- Trial name
- NCT04670302
- Testing
- Tendon repair procedure, Tendon repair augmented with AAdMSC-HAM composite
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr. Soetomo General Hospital
Trophic Ulcer
Treatment of Patients With Trophic Ulcers Using Mesenchymal Stem Cells
Treatment of patients with trophic ulcers using injection of autologous adipose-derived mesenchymal stem cells around and inside the wound
- Trial name
- NCT04457037
- Testing
- Autologous adipose-derived mesenchymal stem cells
- Where
- Belarus
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Scars, Delayed Wound Healing
Nanofat on Wound Healing and Scar Formation
This study will evaluate the effectiveness and safety of intradermal injection of Nanofat on wound healing and scar formation.
- Conditions
- Scars, Delayed Wound Healing, Hypertrophic Scar, Post Inflammatory Hyperpigmentation
- Trial name
- NFWHSF (NCT03850119)
- Testing
- Nanofat injection
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Sepsis
Randomized, Parallel Group, Placebo Control, Unicentric, Interventional Study to Assess the Effect of Expanded Human Allogeneic Adipose-derived Mesenchymal Adult Stem Cells on the Human Response to Lipopolysaccharyde in Human Volunteers
Phase I, randomized, parallel group, placebo control, unicentric, interventional study. Thirty two healthy male volunteers aged between 18-35 years will be randomized into the eASCs or placebo group if they meet all the inclusion…
- Trial name
- CELLULA (NCT02328612)
- Testing
- Intravenous infusion of cells
- Where
- Netherlands
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Tigenix S.A.U.
Skin Aging, Transepidermal Water Loss
Microneedle Versus Fractional CO₂ Laser for Skin Aging Treatment With Stem Cell Secretome in Indonesian Adult Women
Evidences regarding the effectiveness of adipose-derived mesenchymal stem cells (ADMSCs) secretome to alleviate skin aging have been extensively available, yet no studies hitherto directly investigated the best administration…
- Trial name
- NCT05508191
- Testing
- Fractional CO₂ Laser, Microneedle
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shannaz Nadia Yusharyahya
Keloid, Autologus Adipose Derived Stem Cells
Autologous Adipose Derived Stem Cells Transplantation in the Treatment of Keloids.
Keloids are the most common disfiguring skin disorder affecting colored population with a prevalence of upto 16%. Autologous adipose derived stem cells have been found to have potential therapeutic benefits however limited…
- Conditions
- Keloid, Autologus Adipose Derived Stem Cells, Feasibility, Safety
- Trial name
- NCT04553159
- Testing
- Autologous adipose derived stem cells
- Where
- Uganda
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Makerere University
Rotator Cuff Tear, Rotator Cuff Tendinitis
Autologous Adult Adipose-Derived Regenerative Cell Injection Into Chronic Partial-Thickness Rotator Cuff Tears
The purpose of this investigation is to evaluate the safety and superior effectiveness in functional improvement in patients with partial-thickness rotator cuff tears (PTRCTs) after the administration of a single injection of…
- Trial name
- NCT03752827
- Testing
- Adipose Derived Regenerative Cells, Corticosteroid
- Where
- 14 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- InGeneron, Inc.
Atrophic Scar
Safety and Efficacy of Autologous Adipose-derived Mesenchymal Stem Cells Therapy in Adults With Atrophic Scars
The purpose of this clinical trial was to evaluate the safety and efficacy of a single administration of TRTP-101 in adults with atrophic scars.
- Trial name
- NCT07474467
- Testing
- TRTP-101
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- CellinCells
Rotator Cuff Tears
Safety and Efficacy of Adult Adipose-Derived Stem Cell Injection Into Partial Thickness Rotator Cuff Tears
Extension Study of Protocol RC-001- Safety and Efficacy of Adult Adipose-Derived Stem Cell Injection into Partial Thickness Rotator Cuff Tears.
- Trial name
- NCT04077190
- Testing
- Adipose-derived stem cells, cortisone injection
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- InGeneron, Inc.
Adypose Mesenchimal Stem Cell, Ligament Rupture
Regeneration of Posterior Cruciate Ligament Injury Using Hypoxic Conditioned Allogenic Adipose Mesenchymal Stem Cell and Condition Medium
Transplantation of Allogenic Adipose Mesenchimal Stem cell in hypoxic cultur condition with Ligament- derived conitioned medium can enhance regeneration of posterior cruciate ligament rupture
- Conditions
- Adypose Mesenchimal Stem Cell, Ligament Rupture, Ligament Derived Conditined Medium
- Trial name
- NCT04889963
- Testing
- adypose mesenchymal conditioned medium and ligament derived conditioned medium
- Where
- Indonesia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Abnormally Healing Wounds, Scars
Safety of Adipose-Derived Stem Cell Stromal Vascular Fraction
A single-arm, open-labeled, single-center, descriptive and exploratory safety trial using ADSC-SVF-002. ADSC-SVF-002 is an autologous adipose derived stem cell (ADSC)-containing stromal vascular fraction (SVF) obtained from…
- Conditions
- Abnormally Healing Wounds, Scars, Soft Tissue Defects
- Trial name
- NCT02590042
- Testing
- ADSC-SVF-002
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- AdiSave Inc.
Androgenetic Alopecia
Hair Regeneration in Androgenetic Alopecia
This clinical trial study aims to compare the effectiveness and safety of secretome from ADSCs with minoxidil in AGA cases, to provide future reference or standard in the application of cell-based therapy and its derivatives in…
- Trial name
- NCT06066827
- Testing
- Minoxidil Topical, Secretome from adipose-derived stem cells, Combination of minoxidil and secretome from adipose-derived stem cells
- Where
- 2 sites in Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. dr. Lili Legiawati, SpKK(K)
COVID-19
A Clinical Trial to Determine the Safety and Efficacy of HB-adMSCs to Provide Protection Against COVID-19
Hope Biosciences is conducting a research study of an investigational product called autologous adipose-derived mesenchymal stem cells (abbreviated as HB-adMSCs) to provide immune support against COVID-19.
- Trial name
- NCT04349631
- Testing
- HB-adMSCs
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hope Biosciences Research Foundation
Micromastia
Grafting of Autologous Adipose Stromal Cell Trial
Grafting of autologous stromal cell trial is a prospective study comparing routine fat grafting versus stromal vascular fraction enriched fat grafting.
- Trial name
- GAASC (NCT02116933)
- Testing
- Adipose Derived Stem Cells, SVF Enriched Autologous Fat Grafting
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tower Outpatient Surgical Center
Androgenic Alopecia
The Effect of Allogeneic Human Adipose Derived Stem Cell Component Extract on Androgenic Alopecia
This randomized, placebo-controlled, double-blind study evaluates the efficacy and tolerability of the allogeneic human adipose derived stem cell component extract on androgenic alopecia in relatively healthy adults.
- Trial name
- NCT02594046
- Testing
- stem cell component extract
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Aging Well, Regenerative Medicine
MSC Infusion for Anti-aging and Regenerative Therapy
To evaluate the safety and efficacy of human Mesenchymal Stem Cell (hMSC) infusion therapy, in preserving general wellness and ameliorating or reversing the effects of aging in our study population
- Trial name
- REGEN (NCT04174898)
- Testing
- human Mesenchymal Stem Cell (MSC) infusion therapy
- Where
- Malaysia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Landmark Medical Centre Sdn Bhd
Alveolar Bone Loss, Atrophy
Buccal Fat Pad Derived Stem Cells With Cortical Tenting in Posterior Mandible Reconstruction
In this study the buccal fat pad derived stem cells (BFPSCs) is harvested from buccal fat pad tissue of the patients receiving posterior mandible augmentation.
- Trial name
- NCT02745366
- Testing
- BFPSC+FDBA+PRF, FDBA+PRF
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Skin Rejuvenation
Evaluation of the Efficacy and Tolerability of Autologous Adipose Tissue Derived Stem Cells on Facial Rejuvenation
This study is to evaluate the efficacy and tolerability of autologous adipose tissue derived stem cells in facial rejuvenation.
- Trial name
- NCT03928444
- Testing
- intradermal injection of adipose derived stem cells to one side of the face, intradermal injection of saline to one side of the face
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Alexandria University