Clinical trials: Adolescent
Hyperkyphosis, Adolescent, Muscle Activation
Schroth and Scapular Muscle Activation in Hyperkyphosis
This randomized controlled trial aims to investigate the effects of Schroth exercises on scapular muscle activation in children with thoracic hyperkyphosis.
- Conditions
- Hyperkyphosis, Adolescent, Muscle Activation, Scapula; Deformity, Acquired, Exercise Therapy
- Trial name
- NCT06907914
- Testing
- Schroth
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University - Cerrahpasa
Polycystic Ovary Syndrome
Auricular Acupressure (AA) For Overweight/Obese Adolescent and Young Polycystic Ovary Syndrome ( PCOS)
The purpose of this trial is to investigate the effect and safety of auricular acupressure on adolescent and young women with PCOS.
- Trial name
- NCT02326714
- Testing
- Auricular acupressure
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Major Depressive Disorder
VR-Moodboost; an Innovative Virtual Reality Treatment for Adolescents With Depression
Major depressive disorder (MDD) is a prevalent and disabling mental health condition. A recent meta-analysis shows that across all forms of psychotherapy, only 43% of all depressive patients fully recover from MDD and relapse…
- Trial name
- VR-Moodboost (NCT05486676)
- Testing
- VR-Moodboost; a Virtual Reality intervention for depression to enhance positive affect and reduce depressive symptoms.
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Claudi Bockting
Overweight, Glucose Metabolism Disorders
The Physical Activity and Nutrition in Children (PANIC) Study
The Physical Activity and Nutrition in Children (PANIC) Study is a single-centre controlled trial on the effects of a combined physical activity and dietary intervention on cardiometabolic risk factors and other health outcomes…
- Conditions
- Overweight, Glucose Metabolism Disorders, Lipid Metabolism Disorders, Blood Pressure
- Trial name
- PANIC (NCT01803776)
- Testing
- lifestyle counseling
- Where
- Finland
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Hepatitis B
Hepatitis B Seroepidemiology Among Young Adults
Taiwan has launched a successful nationwide neonatal hepatitis B immunization since July 1, 1984. It successfully decreased the incidence of hepatitis B virus infection, the hepatitis B carrier rate as well as liver diseases…
- Trial name
- NCT01973582
- Where
- Taiwan
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Crohn's Disease
A Study to Assess Safety and Effectiveness of Adalimumab for Treating Children and Adolescents With Crohn's Disease in Real Life Conditions
The primary objective of this study is to evaluate long-term effectiveness of adalimumab in pediatric participants starting a treatment for Crohn's disease in real life conditions, namely to describe the time to loss of clinical…
- Trial name
- LEA (NCT03017014)
- Where
- 24 sites in France
- Volunteers
- 62 people
- Sponsor
- AbbVie
Chronic Migraine
Cannabis for Chronic Headaches in Adolescents: the CAN-CHA Trial
Chronic headaches are a major cause of disability among adolescents. Cannabis products have supported the management of headaches in adults and may play a role in pediatric chronic pain.
- Trial name
- CAN-CHA (NCT05337033)
- Testing
- MPL-001
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Liver Transplant; Complications, Quality of Life
Starzl Network Patient Reported Outcomes
This study uses a smartphone application/web interface (RealTime Clinic; RTC) to collect patient and parent reports of a pediatric liver transplant recipient's quality of life (QOL), and examines the extent to which QOL…
- Conditions
- Liver Transplant; Complications, Quality of Life, Child Behavior, Adolescent Behavior
- Trial name
- SPaRO (NCT05241847)
- Testing
- PeLTQL delivery via electronic means
- Where
- 7 sites in United States, Canada
- Volunteers
- 200 people
- Sponsor
- University of Pittsburgh
Diabetes
Use of MiniMed 780G System in Children and Adolescents
Hybrid closed-loop technology have shown that it improves glycemic control parameters, but the investigators do not have sufficient data at more than 6 months of follow-up, allowing us to describe the effectiveness of these…
- Trial name
- NCT05591690
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Montpellier
Child
Reliability and Validity of Turkish Version of PEM-CY
The Participation and Environment Measure for Children and Youth (PEM-CY) is the first instrument that combines parental assessment of children's participation in home, school, and community activities with qualities of each…
- Trial name
- NCT02485314
- Testing
- Participation
- Where
- Turkey (Türkiye)
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy, Minor Traumatic Brain Injury (TBI)
An Investigator Initiated Study to Evaluate the Effectiveness of Brain Network Activation (BNA™) Technology in the Management of Sport Related Concussion
Currently, there is no direct, reliable, bed-side, and non-invasive method for assessing changes in brain activity associated with concussion.
- Trial name
- NCT01963247
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- ElMindA Ltd
Acute Pain
Pharmacokinetics and Safety of MNK-155 in Postsurgical Adolescent Subjects With Moderate to Severe Acute Pain
An open-label study of the pharmacokinetics (PK) and safety of MNK-155 in postsurgical adolescent subjects aged 12 to 17 years with moderate to severe acute pain.
- Trial name
- NCT02767349
- Testing
- MNK-155
- Where
- United States
- Sponsor
- Mallinckrodt
Pertussis
2-year Follow-up After a Single Dose Acellular Pertussis Vaccination
In July 2015-November 2016, a phase II/III randomized, observer-blind,controlled study of two acellular Pertussis vaccines (aP standalone and TdaP combined vaccined) manufactured by BioNet-Asia Co., Ltd.
- Trial name
- NCT04113655
- Testing
- Pertagen (aP BioNet), Boostagen (TdaP BioNet), Adacel
- Where
- 2 sites in Thailand
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Orthodontic Appliance Complication
Stability of Maxillary Anterior Teeth After Two Years of Retention in Adolescents Comparing Two Bonded and a Vacuum-formed Retainer
After orthodontic treatment 3 different retention devices will be compared.Thirty patients in each group; Group 1) Bonded retainer 13-23, Group 2)Bonded retainer 12-22 and Group 3) Vacuum-formed retainer covering all erupted…
- Trial name
- NCT04616755
- Testing
- Measuring changes of Little´s irregularity index ( sum of 5 contact point discrepancies together) measured in mm 2 years after retention have been I place.
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kronoberg County Council
Femoral Head Avascular Necrosis
The Use of Bisphosphonates in the Treatment of Avascular Necrosis of the Femoral Head
To determine the safety and effectiveness of pamidronate in patients with radiographically proven avascular necrosis which are the result of unstable (acute) slipped capital femoral epiphysis, traumatic proximal femur fractures…
- Trial name
- NCT02007915
- Testing
- Pamidronate Disodium
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- The Hospital for Sick Children
Chronic Hand Eczema
Efficacy and Safety of Delgocitinib Cream in Adolescents 12-17 Years of Age With Moderate to Severe Chronic Hand Eczema
The purpose of this trial is to test if delgocitinib cream is effective in treating chronic hand eczema (CHE) and to find out what side effects it may have compared with a cream vehicle with no active medical ingredient in…
- Trial name
- DELTA TEEN (NCT05355818)
- Testing
- Delgocitinib, Cream vehicle
- Where
- 37 sites in Australia, Belgium and 5 more
- Volunteers
- 98 people
- Sponsor
- LEO Pharma
External Focus (e.g., Performing the Exercise by Directing the Individual's Attention to a Laser Beam), Exercise Training
The Effects of Thrower's Ten Exercises Performed With an External Focus
The aim of this study is to comprehensively investigate the effects of the Thrower's Ten exercise program-commonly recommended to enhance shoulder stability and strength in athletes-when applied using an external focus of…
- Conditions
- External Focus (e.g., Performing the Exercise by Directing the Individual's Attention to a Laser Beam), Exercise Training, Adolescent
- Trial name
- The Effects of (NCT07546890)
- Testing
- Exercise, Exercise with neutral attentional focus
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
IBD (Inflammatory Bowel Disease), IBD
Ex-vivo Confocal Imaging and Proteomic Profiling to Determine Treatment Response in Children With IBD
This study aims to test the overall hypothesis that the membrane tissue binding capacity of cytokines in the biopsied tissue of patients with Inflammatory Bowel Disease (IBD) is predictive of/strongly correlated to clinical…
- Conditions
- IBD (Inflammatory Bowel Disease), IBD, IBD - Inflammatory Bowel Disease
- Trial name
- NCT07121920
- Testing
- Confocal Laser Endomicroscopy
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Cook Children's Health Care System
Bronchospasm, Activity/Exercise Induced Bronchospasm
A Study Measuring Asthma Control In Pediatric And Adolescent Subjects Whose Asthma Is Worsened By Activity Or Exercise
During this study, your child will need to attend up to 5 office visits and maintain regular telephone contact with the clinic. Certain office visits will include physical exams, medical history review, exercise challenge test…
- Trial name
- NCT00118716
- Testing
- Fluticasone propionate/salmeterol, Fluticasone Propionate
- Where
- 50 sites in United States
- Volunteers
- 248 people
- Sponsor
- GlaxoSmithKline
Schizophrenia, Autism-Related Irritability
A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents
The purpose of this study is to evaluate the long-term safety and tolerability of Xanomeline and Trospium Chloride for the treatment of psychiatric disorders in children and adolescents
- Trial name
- NCT07424404
- Testing
- KarXT, KarX-EC
- Where
- 104 sites in United States, Australia and 9 more
- Volunteers
- 400 people
- Sponsor
- Karuna Therapeutics, Inc., a Bristol Myers Squibb company
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