Clinical trials: Adolescent
Youths At-risk for Drug Use/Abuse
Neurological Influences on Drug Prevention Intervention
In this R01 study, a randomized clinical trial is proposed to evaluate the efficacy of a drug abuse prevention intervention for indicated middle school youth that coordinates family and teen-based components.
- Trial name
- NCT00198939
- Testing
- Integrated Family and Cognitive-Behavioral Drug Prevention Intervention, Psychoeducation
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Florida
Opioid Misuse
Prevention of Opioid Misuse and Overdose Deaths Among Hispanic/Latinx Adolescents: A Family-based Perspective
The purpose of this study is to develop culturally-competent family-focused educational modules targeting opioid knowledge and attitudes (including targeting safe storage and prevention of accidental opioid overdose in adolescent…
- Trial name
- NCT06303804
- Testing
- Educational videos
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Systemic Lupus
Use of Social Media to Improve Medication Adherence in Adolescents and Young Adults With Systemic Lupus
The goal of this study was to examine the effect of an online educational program with and without a social media experience.The primary goal of this study was to determine whether medication adherence would be improved by having…
- Trial name
- NCT03218033
- Testing
- Social Media
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Patellofemoral Pain Syndrome
Multidimensional Diagnostics and Effect of Activity Modification in Young Adolescents With Patellofemoral Pain
Problem: Adolescent patellofemoral pain (PFP) is a major problem worldwide and affects 7% of adolescents. Adolescents with PFP have long-lasting severe pain and low quality of life.
- Trial name
- NCT02402673
- Testing
- Temporary activity modification and graded exercises
- Where
- Denmark
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Cardiomyopathies
Body Surface Area Prediction Impacts on Ventricular Dilatation Prevalence
The goals of this observational study are to investigate the accuracy of different predictive equations for body surface area (BSA) estimation and to evaluate the impact of different BSA normalizations on ventricular dilatation…
- Trial name
- NCT06939205
- Testing
- Assessment of body surface area and assessment ventricular dilatation prevalence
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Alcohol Drinking, Self Efficacy
ChangeGradients: Promoting Adolescent Health Behavior Change
As most adolescents visit a healthcare provider once a year, health behavior change interventions linked to clinic-based health information technologies hold significant promise for improving healthcare quality and subsequent…
- Conditions
- Alcohol Drinking, Self Efficacy, Adolescent Behavior, Risk-Taking
- Trial name
- NCT04110756
- Testing
- ChangeGradients
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sleep Quality, Implementation
Cascading A Healthy Sleep Intervention In Vocational Education
Sleep is crucial for the mental, cognitive and physical health of adolescents. However, teenagers in 2024 sleep less and less and their sleep is of poorer quality.
- Trial name
- NCT07030556
- Testing
- Healthy Sleep Intervention, Co-creation process, Training for teachers
- Where
- Belgium
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Ghent
Hypoxemia
The Effects of Wearing a Face Mask During Exercise in Youth Hockey Players During COVID-19
There is concern that wearing a face mask during COVID will affect oxygen uptake, especially during intense exercise. COVID transmission is especially prevalent in sports such as hockey, where there is close contact between…
- Trial name
- NCT04874766
- Testing
- Wingate exercise test and on-ice testing while wearing a face mask
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Attention Deficit Disorder With Hyperactivity, Attention-Deficit Disorder in Adolescence
TM Meditation in Children With ADD/ADHD
Attention-deficit/hyperactivity disorder (ADHD) is one of the most common developmental disorders experienced in childhood, with limited options for effective pharmacological treatment.
- Trial name
- NCT03817593
- Testing
- Transcendental Meditation (TM)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Attenuated Psychosis Syndrome
Exercise and Markers of Medial Temporal Health in Youth At-risk for Psychosis
The goal of this proposal is to test the feasibility and effectiveness of cardiovascular exercise in promoting brain health and improving related symptoms (e.g., hearing sounds that are not there, feeling emotionally detached…
- Trial name
- NCT02155699
- Testing
- Exercise 1, Exercise 2
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Meningitis, Meningococcal
A Global Phase 3 Safety Study of 120 mcg rLP2086 Vaccine in Adolescents and Young Adults Aged 10 to 25 Years
A multicenter phase 3 safety trial in which 5,700 subjects will be assigned in a 2:1 ratio to receive 120 μg rLP2086 vaccine in a 0, 2, 6 month schedule or control.
- Trial name
- NCT01352793
- Testing
- rLP2086 vaccine, control
- Where
- 86 sites in United States, Australia and 10 more
- Volunteers
- 5,715 people, healthy volunteers welcome
- Sponsor
- Pfizer
Human Papilloma Virus, Tdap - Tetanus, Diphtheria and Acellular Pertussis Vaccination
High and Low Resource Interventions to Promote HPV Vaccines
Human Papillomavirus (HPV) is a significant public health issue affecting nearly 14 million people in the United States. HPV can lead to cervical, oropharyngeal, anal, and penile cancers as well as genital warts.The purpose of…
- Conditions
- Human Papilloma Virus, Tdap - Tetanus, Diphtheria and Acellular Pertussis Vaccination, Meningitis, Meningococcal, Communication
- Trial name
- NCT03824093
- Testing
- AFIX Only, AFIX+ Provider Communication Training
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Well-being, Depression
Computerized Single-Session Interventions for Indian Adolescents
The overall aim of this project is to understand if single-session interventions are acceptable, culturally appropriate, and effective for Indian adolescents.
- Conditions
- Well-being, Depression, Anxiety
- Trial name
- NCT03982563
- Testing
- Growth Mindset, Gratitude, Behavioral Activation
- Where
- 4 sites in India
- Volunteers
- 958 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Obesity, Childhood
Pilot Study of Probiotics in Pre-diabetic Adolescents
This study evaluates the feasibility and effect of probiotics on glycemic control in obese adolescents.
- Trial name
- ProDP (NCT03109587)
- Testing
- Vivomixx
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Childhood Obesity, Cardiovascular Disease
The Effects of California Strawberries on Parameters of Cardiovascular Health
The prevalence of childhood obesity has been increasing over the past couple of decades. Similar to adults, overweight and obesity in young children and adolescents is associated with an increased number of cardiovascular risk…
- Trial name
- NCT01705093
- Testing
- flavonoid-rich freeze-dried strawberry powder, macronutrient-matched control powder
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Condomless Sex, Sexual Assault
Evaluating a Digital Intervention to Improve Adolescent Condom Use and Communication
The purpose of this study is to test the effectiveness, likability, and implementation potential of PACT, an adapted digital program to teach non-heterosexual adolescent boys about sexual consent and condom negotiation in a…
- Trial name
- NCT06878755
- Testing
- Promoting Assertive Communication among Teens (PACT), Healthy Minds
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- North Carolina Agriculture & Technical State University
Healthy, Minor Traumatic Brain Injury (TBI)
An Investigator Initiated Study to Evaluate the Effectiveness of Brain Network Activation (BNA™) Technology in the Management of Sport Related Concussion
Currently, there is no direct, reliable, bed-side, and non-invasive method for assessing changes in brain activity associated with concussion.
- Trial name
- NCT01963247
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- ElMindA Ltd
Opioid-use Disorder
Feasibility of Pediatric Emergency Department-Initiated Treatment for Adolescents With Opioid Use Disorder
ED-initiated buprenorphine with brief intervention and facilitated referral to treatment has been shown to be highly successful in increasing treatment engagement rates and reducing opioid use among adults.
- Trial name
- PEDsTREATOUD (NCT04737603)
- Testing
- ED-Initiated treatment with buprenorphine / naloxone
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Davis
Overweight and Obesity
Inhibitory Control and Pediatric Weight Management
The purpose of this pilot study is to explore the benefits of supplementing the Kurbo online program with a cognitive training game (PolyRules!) among youth ages 7-13 with overweight or obesity.
- Trial name
- NCT04747548
- Testing
- Kurbo Only, Kurbo + PolyRules!
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Healthy Lifestyle Behaviors, Depressive/Anxiety Symptoms
COPE/Healthy Lifestyles for Teens: A School-Based RCT
The prevention and treatment of obesity and mental health disorders in adolescence are two major public health problems in the United States today.
- Trial name
- NCT01704768
- Testing
- COPE/Healthy Lifestyles TEEN Program., Healthy Teens Attention Control Program
- Where
- United States
- Volunteers
- 1,219 people, healthy volunteers welcome
- Sponsor
- Arizona State University
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