Clinical trials: Adolescent Depression
Depressive Symptoms, Anxiety Symptoms
Effects of Inserting Exercises During Physical Education Classes on Anxiety and Depression Symptoms in Adolescents
The main objective of this project will be to verify if the insertion of diaphragmatic, cardiorespiratory and strength breathing exercises and cooperative sports activities in Physical Education classes, during a period of 12…
- Trial name
- NCT05561192
- Testing
- Diaphragmatic breathing exercises, Cardiorespiratory and strength exercise, Cooperative sports activities group
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Depression - Major Depressive Disorder
Efficacy and Safety of Transcranial Alternating Current Stimulation (tACS) in Adolescents With First-episode Depression Who Are Drug-naive: A Randomized, Double-blind, Controlled Pilot Study
To evaluate the efficacy of tACS treatment.To determine whether tACS can accelerate symptom remission, improve clinical response rates, and facilitate the recovery of emotional and cognitive functions through standardized…
- Trial name
- NCT07185464
- Testing
- tACS
- Where
- China
- Volunteers
- 30 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Anxiety, Depression
Student Outcomes of Integrative Mental Health Services
The study will compare the impact of Child STEPs (see Weisz et al., 2012) versus usual school-based therapy on students' mental health and school-related outcomes, and test whether changes in school outcomes are mediated by…
- Conditions
- Anxiety, Depression, Trauma, Behavior Problems
- Trial name
- NCT02877875
- Testing
- Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, and Conduct Problems, Monitoring and Feedback System, Treatment as usual
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Harvard University
Adolescent - Emotional Problem, Agent
A Virtual Peer Agent for Counseling Adolescents With Stressful Life Events
This study aims to develop and evaluate a virtual companion agent for providing psychological support to adolescents who have recently experienced stressful life events. This is a single-arm, pre-post pilot trial.
- Conditions
- Adolescent - Emotional Problem, Agent, Psychological, Conversational
- Trial name
- NCT07305064
- Testing
- Virtual Peer Agent Counseling
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Sun Yat-sen University
Depression, Substance-Related Disorders
Middle School to High School Transition Project: Depression and Substance Abuse Prevention
This study will implement a school-based program to prevent depression, academic failure, and substance use in at-risk adolescents transitioning from middle school to high school.
- Trial name
- CAST-T/HSTS (NCT00071513)
- Testing
- CAST-T/HSTS, Brief Intervention
- Where
- United States
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- University of Washington
Depression Anxiety Disorder, Psychological Distress
Evaluating the Effectiveness of a School-based Stepped Care Treatment Model for Adolescent Depression in Pakistan
This study aims to test the effectiveness of a stepped-care model to reduce depressive symptoms in adolescents in school settings in Pakistan.
- Conditions
- Depression Anxiety Disorder, Psychological Distress, Well-Being, Psychological
- Trial name
- SMART-STEP (NCT07399314)
- Testing
- Universal Intervention & CBT-based Guided Self-Help Application
- Where
- Pakistan
- Volunteers
- 600 people
- Sponsor
- Global Institute of Human Development
Depressive Symptoms
School Adolescent Mood Project: Efficacy of IPT-AST in Schools
This school-based randomized controlled trial will: a) examine the effects of telehealth-administered Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST), an evidence-based depression prevention program, as compared…
- Trial name
- SAM (NCT04109716)
- Testing
- Interpersonal Psychotherapy - Adolescent Skills Training, Services as usual
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Children's Hospital of Philadelphia
Mental Depression, Mental Stress
Mind Power - A CBT Based Program for Adolescents
The purpose of this study is to strengthen school achievement and positive mental health, and to prevent and reduce school dropout and mental distress among high school students.
- Conditions
- Mental Depression, Mental Stress, Mental Health Wellness 1
- Trial name
- NCT03647826
- Testing
- Mind Power Intervention
- Where
- Norway
- Volunteers
- 1,673 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Major Depressive Disorder (MDD)
Evaluation of the Acceptability, Feasibility and Exploration of the Efficacy of an Integrated Care Pathway CARIBOU
Problem statement. Major Depressive Disorder (MDD) is a significant concern among adolescents, characterized by episodes of mood changes, cognitive symptoms, and neurovegetative dysfunction, often lasting months or even years…
- Trial name
- CARIBOU-FR (NCT07806825)
- Testing
- CARIBOU Integrated Care Pathway, Treatment as Usual (TAU)
- Where
- Chile
- Volunteers
- 72 people
- Sponsor
- Universidad de los Andes, Chile
Depression
Harnessing Network Science to Personalize Scalable Interventions for Adolescent Depression (TRACK to TREAT Phase 2)
We will recruit 216 subjects meeting the eligibility criteria. After completing a baseline battery session via secure video conferencing and 3-week phone survey period, adolescents will be randomly assigned to receive 1 of 3…
- Trial name
- NCT04607902
- Testing
- Supportive Therapy SSI, Behavioral Activation SSI, Growth Mindset SSI
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- Stony Brook University
Anxiety Disorders, Depressive Disorder
Study on Mental Health Promoting Effects of Natural Psychotherapy for Adolescents
This randomized controlled trial aims to evaluate the efficacy of a universal intervention based on Natural Psychotherapy in reducing anxiety and depressive symptoms among primary and middle school students.
- Conditions
- Anxiety Disorders, Depressive Disorder, Mental Health
- Trial name
- NP-A-MHP (NCT07639476)
- Testing
- Multi-modal Nature-based Meditation, Intervention diary
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Beijing HuiLongGuan Hospital
Depression
The Efficacy of a Depression Intervention for Adolescents With Depression and Sleep Disturbances
The focus of this study is on identifying how Interpersonal Psychotherapy for Adolescents (IPT-A) with depression works to change sleep and related biological markers found in saliva, namely cortisol and pro-inflammatory cytokine…
- Trial name
- NCT02429674
- Testing
- TranS-C and IPT-A
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- New York State Psychiatric Institute
Bipolar Disorder, Major Depressive Disorder
Early Intervention for Youth at Risk for Bipolar Disorder
Children or teens with mood swings or depression who have a parent with bipolar disorder are at high risk for developing bipolar disorder themselves.
- Trial name
- NCT01483391
- Testing
- Enhanced Care, Family-Focused Treatment
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of California, Los Angeles
Mental Health Issue, Depression
Just-in-Time Training for Youth Mentors
This study will evaluate the usability, feasibility, and acceptability of a novel multi-level Just-In-Time Training (JITT) implementation strategy (JITT-EBP) that aims to equip mentors and mentor supervisors to implement…
- Conditions
- Mental Health Issue, Depression, Anxiety
- Trial name
- NCT07129070
- Testing
- Interpersonal Psychotherapy-Adolescent Skills Training via Just-In-Time Training (JITT) implementation strategy, Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST) implemented via usual training
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Depression
Effect of Virtual Reality on Depression in Adolescent Females
The purpose of this study is to investigate the effect of virtual reality on depression in adolescent females.
- Trial name
- NCT07452341
- Testing
- Virtual reality headset, Selective serotonin reuptake inhibitors(SSRIs)
- Volunteers
- 48 people
- Sponsor
- Cairo University
Major Depressive Disorder
rTMS for Depressed Teens: A Sham-Controlled Trial, Part 2
This research proposal aims to better understand the neurobiology of depression in adolescents and how repetitive transcranial magnetic stimulation (rTMS) may therapeutically impact brain function and mood.
- Trial name
- NCT01804296
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Paul E. Croarkin
Cyberbullying, Depression
Building Resilience in Cyberbullying Victims
This study evaluates the effectiveness of a wise intervention based on self-affirmation (SA) and Implicit Theories of Personality (ITP) building resilience in victims.
- Conditions
- Cyberbullying, Depression, Non Suicidal Self Injury, Social Anxiety
- Trial name
- Resilience (NCT04509531)
- Testing
- Wise Intervention (SA, ITP and resilience), Standard preventive intervention
- Where
- Spain
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Trauma, Anxiety
The Ukrainian Student Problem Solving Project
The purpose of this study is to test the effectiveness of a universal, digital, single-session intervention for youth mental health, functioning, and well-being.
- Conditions
- Trauma, Anxiety, Depression, Child Behavior
- Trial name
- NCT06064578
- Testing
- Project SOLVE
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- Harvard University
Suicidal Ideation
Stratified-Care School-Based Intervention for Adolescent Suicidal Ideation
Background. Suicidal ideation and depressive symptoms are highly prevalent among adolescents, with suicide representing a leading cause of death in this age group worldwide.
- Trial name
- NCT07063914
- Testing
- Reframe-IT and CARIBOU
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Universidad de los Andes, Chile
Treatment Resistant Depression
Repetitive Transcranial Magnetic Stimulation for Adolescent Depression: Efficacy, Predictive Biomarkers, and Mechanisms
This study will be an open-label 6-week (30 session) trial of active repetitive transcranial magnetic stimulation (rTMS) using a fixed frequency (10 Hz) but varying stimulation intensities using a 3+3 study design for safety and…
- Trial name
- NCT02611206
- Testing
- Active Repetitive Transcranial Magnetic Stimulation (rTMS): intensity 80% MT, Device: Active Repetitive Transcranial Magnetic Stimulation (rTMS); Stimulation intesity: 100% of MT, Device: Active Repetitive Transcranial Magnetic Stimulation (rTMS); Stimulation intesity: 120% of MT
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Minnesota