Clinical trials: Adolescent Pregnancy
Endometriosis
Interest of Salivary Signature of Endometriosis in the Heathcare Pathway of Adolescent
ADOmiARN is a multicentre, prospective, longitudinal, non-interventional, observational study carried out in obstetrics, gynecology and pediatrics departments in France and in Belgium.
- Trial name
- ADOmiARN (NCT05928442)
- Testing
- in vitro diagnostic medical device, Completion of a self-questionnaire
- Where
- 13 sites in Belgium, France and 1 more
- Volunteers
- 80 people
- Sponsor
- ZIWIG
Teen Pregnancy Prevention
Effect of a Culturally-based Intervention on Sexual Risky Behavior Among Young American Indian Adolescents
Youth who participate in the Circle of Life (COL) program will report less sexual risk taking behavior compared to youth who do not receive the program.
- Trial name
- COL/AS+ (NCT01698073)
- Testing
- mCOL, AS+
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Diabetic Kidney Disease, Hyperuricemia
Uric Acid Lowering Trial in Youth Onset T2D
Adolescents and young adults with youth-onset type 2 diabetes (T2D) are disproportionally impacted by hyperuricemia compared to non-diabetic peers and youth with type 1 diabetes (T1D).
- Conditions
- Diabetic Kidney Disease, Hyperuricemia, Diabetes, Diabetes Mellitus, Type 2
- Trial name
- ULTRA-T2D (NCT03899883)
- Testing
- Pegloticase 8 MG/ML [Krystexxa]
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Colorado, Denver
Kallmann Syndrome, Hypogonadotropic Hypogonadism
Human Menopausal Gonadotropin Combining With Human Chorionic Gonadotropin Treat Congenital Hypogonadotropic Hypogonadism
Observe the therapeutic efficacy of human menopausal gonadotropin combining with human chorionic gonadotropin in adolescent boys with congenital hypogonadotropic hypogonadism.
- Trial name
- NCT02880280
- Testing
- Human Menopausal Gonadotropin, Human Chorionic Gonadotropin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Beijing Children's Hospital
Congenital Adrenal Hyperplasia
Tweens to Teens Project at Penn State
The goal of this study is to help investigators to understand more about the development of characteristics related to being male or female (what is called gender development).
- Trial name
- T2T@PSU (NCT01184651)
- Testing
- Questionnaires/Interviews
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Penn State University
Urinary Tract Infections
A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)
The study will be conducted to evaluate the therapeutic response (combined per participant microbiological and clinical response) of oral gepotidacin compared to oral nitrofurantoin for treatment of uncomplicated UTI (acute…
- Trial name
- NCT04020341
- Testing
- Gepotidacin, Nitrofurantoin
- Where
- 103 sites in United States, Bulgaria and 10 more
- Volunteers
- 1,531 people
- Sponsor
- GlaxoSmithKline
Bacterial Vaginosis
Open-Label Study to Evaluate Safety of A Single Dose of SYM-1219
This is a Phase 3, multi-center, prospective, open-label study to evaluate the safety of SYM-1219 granules containing 2 grams of secnidazole in women and postmenarchal adolescent girls with bacterial vaginosis.
- Trial name
- NCT02452866
- Testing
- SYM-1219
- Where
- 40 sites in United States
- Volunteers
- 325 people
- Sponsor
- Symbiomix Therapeutics
Dysmenorrhea, Heavy Menstrual Bleeding
Menstrual Complaints in Adolescents and Adults
The aim of this study is to investigate the prevalence of menstrual complaints and their impact on daily life activities (school/work absence, absence from social activities, sports) in adults and adolescents.
- Conditions
- Dysmenorrhea, Heavy Menstrual Bleeding, Daily Activities, Menstrual Cramps
- Trial name
- MEK app (NCT06921629)
- Testing
- Menstruatie Educatie Kalender (Menstrution Education Calendar) application (MEK-app), Questionnaires
- Where
- Netherlands
- Volunteers
- 2,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Breast Cancer, Ovarian Cancer
Navigation Intervention for Adolescent and Young Adult Cancer Survivors
The investigators propose to: 1) Adapt an evidence-based cancer-focused patient navigation (PN) program for the Adolescent and Young Adult (AYA) cancer survivor population; and 2) Plan and conduct an effectiveness-implementation…
- Conditions
- Breast Cancer, Ovarian Cancer, Cervical Cancer, Testicular Cancer
- Trial name
- NCT07406087
- Testing
- Adapted patient navigation program targeting adolescent and young adult cancer survivors
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Kaiser Permanente
Cervical Cancer, Kaposi Sarcoma
AYAHIV Role-based Responsibilities for Oncology-focused Workforce (ARROW)
Adolescents and young adults living with HIV experience higher premature mortality from cancer than their uninfected peers. In Zambia, because of multilevel barriers, interventions for early diagnosis and optimized treatment to…
- Conditions
- Cervical Cancer, Kaposi Sarcoma, Non Hodgkin Lymphoma
- Trial name
- NCT06004011
- Testing
- ARROW strategies, One-time education
- Where
- Zambia
- Volunteers
- 4,100 people
- Sponsor
- Implenomics
Risk for an Alcohol-Exposed Pregnancy, Risk for Marijuana-Exposed Pregnancy
CHOICES-TEEN Randomized Controlled Trial
This randomized controlled trial will: 1) Test the efficacy of the CHOICES-TEEN (CT) intervention compared with an Attentional Control (AC) condition on reducing the risk of substance-exposed pregnancy (SEP) and HIV/STI among…
- Conditions
- Risk for an Alcohol-Exposed Pregnancy, Risk for Marijuana-Exposed Pregnancy, Risk for Substance-Exposed Pregnancy, HIV Risk
- Trial name
- NCT05368571
- Testing
- CHOICES-TEEN, Health and Life Skills Education
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Danielle Parrish
Pain
Study of Pain Control With Hormonal IUS Insertion
This study aims to compare pain during insertion of the Skyla® IUS using a 100mm visual analog scale (VAS) among 92 young women aged 14 to 22 years randomized to receive a paracervical (n=46) block versus a sham paracervical…
- Trial name
- SOPHI (NCT02352714)
- Testing
- Paracervical Nerve Block
- Where
- 3 sites in United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Adnexal Torsion
Role of Preoperative D-dimer Levels in the Diagnosis of Adnexal Torsion
Adnexal torsion is the fifth most common gynecologic emergency. Thirty percent of all cases of adnexal torsion occur in females younger than 20 years.
- Trial name
- NCT06324565
- Testing
- D-Dimer test
- Where
- 9 sites in Austria, Italy and 1 more
- Volunteers
- 130 people
- Sponsor
- IRCCS Burlo Garofolo
Unprotected Sex, Contraceptive Usage
The Evaluation of Pulse: A Mobile Health App and Teen Pregnancy Prevention Program
This study used a randomized controlled design to evaluate the efficacy of a new mobile app, Pulse, in reducing the incidence of unprotected sex among young women.
- Trial name
- NCT04043130
- Testing
- Pulse
- Where
- United States
- Volunteers
- 2,317 people, healthy volunteers welcome
- Sponsor
- Child Trends
Health Adults, Teenager
Effectiveness of Interventions for Improving HPV Vaccination Cover
Research Problem and Question: The development of prophylactic vaccines against the human papillomavirus (HPV) marks a major scientific and technological advance in the fight against cervical cancer.
- Trial name
- NCT07113236
- Testing
- Instructions, advices, No instructions
- Where
- Colombia
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cancerologia, Columbia
Unprotected Sex, Contraceptive Usage
The Evaluation of Pulse: A Mobile Health App and Teen Pregnancy Prevention Program
This study uses a randomized controlled design to evaluate the efficacy of a new mobile app, Pulse, in reducing the incidence of unprotected sex among young women.
- Conditions
- Unprotected Sex, Contraceptive Usage, Reproductive and Sexual Health Care Utilization
- Trial name
- NCT03253783
- Testing
- Pulse
- Where
- United States
- Volunteers
- 1,304 people, healthy volunteers welcome
- Sponsor
- Healthy Teen Network
Polycystic Ovary Syndrome
Impact of Metformin in Teens With Polycystic Ovary Syndrome (PCOS) on Oral Contraceptive Therapy
Oral contraceptives are known to improve menstrual cycles and symptoms in PCOS, however may increase cholesterol. Metformin, a drug to improve insulin resistance, may benefit metabolic state.
- Trial name
- NCT00283816
- Testing
- Metformin, Oral Contraceptive Pill, Lifestyle Management Program
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Chlamydia
Multi-level Interventions for STD Prevention Among Adolescents
Sexually active adolescents between the ages of 10 and 19 are at extremely high risk for sexually transmitted diseases (STD), including HIV, and teen pregnancy.The overall goal of this research program is to develop, implement…
- Trial name
- NCT00146406
- Testing
- Project Connect
- Where
- United States
- Volunteers
- 36,502 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Abnormal Uterine Bleeding
Evaluation of Abnormal Uterine Bleeding in Adolescents: A Cross Sectional Observational Study
Evaluation of Abnormal Uterine Bleeding in Adolescents: A Cross Sectional Observational Study
- Trial name
- NCT06201767
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Teen Pregnancy Prevention
Evaluation of Momentary Affect Regulation - Safer Sex Intervention
The purpose of the study is to determine the impact of the offer to participate in the Momentary Affect Regulation - Safer Sex Intervention (treatment) relative to the offer to participate in the control condition on…
- Trial name
- MARSSI (NCT04798248)
- Testing
- Momentary Affect Regulation - Safer Sex Intervention (MARSSI), Podcast Health Group
- Where
- 2 sites in United States
- Volunteers
- 405 people
- Sponsor
- The Policy & Research Group