Clinical trials: Adrenalectomy
Adrenalectomy
Robotic Adrenalectomy With Versus Without Indocyanine Green Fluorescence Imaging
This is a prospective randomized study comparing robotic adrenalectomy with versus without intraoperative indocyanine green imaging.
- Trial name
- NCT07813247
- Testing
- indocyanine green imaging
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- The Cleveland Clinic
Mild Autonomous Cortisol Secretion (MACS), Adrenalectomy; Status
Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol Secretion
Mild Autonomous Cortisol Secretion (MACS) is a condition in which an adrenal gland produces excess cortisol and is associated with high blood pressure, diabetes, and weight gain.
- Trial name
- NCT07573163
- Testing
- Tirzepatide, Standard medical treatment
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Alaa Sada
Adrenalectomy; Status
Long-term Blood Pressure Outcome After Unilateral Adrenalectomy for Primary Hyperaldosteronism
To evaluate long-term results of adrenalectomy for primary aldosteronism (PA) and to identify prognostic factors associated. Exhaustive retrospective review of all consecutive patients undergoing adrenalectomy for PA between 2002…
- Trial name
- Hyperaldo (NCT03648294)
- Testing
- adrenalectomy for primary addosteronism
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Primary Aldosteronism Due to Conn Adenoma, Radiofrequency Ablation Treatment
Radiofrequency Ablation Versus Adrenalectomy for Adenoma in Patients With Primary Aldosteronism and Hypertension
Primary aldosteronism (PA) is characterized by hypertension, frequent hypokalaemia, and an inappropriately high aldosterone-to-renin ratio (ARR).
- Conditions
- Primary Aldosteronism Due to Conn Adenoma, Radiofrequency Ablation Treatment, Adrenalectomy
- Trial name
- ADERADHTA2 (NCT07470580)
- Testing
- RFA -radiofrequency ablation, Adrenalectomy
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Toulouse
Adrenalectomy
Laparoscopic Versus Robotic Lateral Transabdominal Adrenalectomy
This study is being done to compare Laparoscopic vs Robotic lateral transabdominal adrenalectomy, these procedures are both standard of care.
- Trial name
- NCT06407024
- Testing
- laparoscopic transabdominal adrenalectomy, robotic transabdominal adrenalectomy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- The Cleveland Clinic
Hyperaldosteronism, Adrenal Venous Sampling
CHina Adrenal Venous saMPling InvestigatiON
Primary aldosteronism (PA) is a major cause of secondary hypertension, yet its optimal diagnosis and management remain challenging.
- Conditions
- Hyperaldosteronism, Adrenal Venous Sampling, Adrenalectomy
- Trial name
- CHAMPION (NCT07252284)
- Testing
- adrenal venous sampling
- Where
- 76 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Adrenalectomy; Status
Robot-assisted vs Laparoscopic Lateral Transabdominal Adrenalectomy
This retrospective study evaluates the safety and the effectiveness of robotic adrenalectomy when compared to laparoscopic approach in patients who underwent minimally-invasive lateral transperitoneal unilateral adrenalectomy
- Trial name
- RvsL-TLA (NCT05853302)
- Where
- Italy
- Volunteers
- 316 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Adrenalectomy
Robot-assisted Adrenalectomy, Feasibility and Results
To date, laparoscopy is considered to be the gold standard technique for adrenalectomy. Robotic surgery is beginning to be used, but no series of more than 300 procedures has yet allowed the morbidity, benefits and learning curve…
- Trial name
- ROBADRE (NCT07110168)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Central Hospital, Nancy, France
Primary Aldosteronism, Secondary Hypertension
PETAL Trial: Impact of Gallium-68 Pentixafor PET-CT on Surgical Outcomes in Primary Aldosteronism
This study is a randomized controlled trial to assess the clinical utility of gallium-68 pentixafor PET/CT in the management of primary aldosteronism (PA).
- Conditions
- Primary Aldosteronism, Secondary Hypertension, Aldosterone-Producing Adenoma, Idiopathic Hyperaldosteronism
- Trial name
- NCT07027254
- Testing
- 68Ga-pentixafor PET/CT
- Where
- 2 sites in South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Pheochromocytoma, Paraganglioma
The Effect and Safety of Omitting Preoperative Alpha-adrenergic Blockade for Normotensive Pheochromocytoma
Pheochromocytoma and paraganglioma (PPGL) are rare neuroendocrine tumors originating from catecholamine producing chromaffin cells in the adrenal medulla and extra-adrenal paraganglia.
- Conditions
- Pheochromocytoma, Paraganglioma, Adrenalectomy; Status, Adrenergics Causing Adverse Effects in Therapeutic Use
- Trial name
- NCT05702944
- Testing
- Phenoxybenzamine
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Seoul National University Hospital
Adrenal Tumor, Adrenalectomy; Status
3D Laparoscopic Adrenalectomies for Adrenal Tumors
The main drawbacks of conventional 2D laparoscopy are limited depth perception and loss of spatial orientation. High-quality 3D laparoscopy systems might improve surgical outcomes for adrenalectomy.
- Trial name
- NCT04905706
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Adrenalectomy
Readmission After Adrenalectomy
to evaluate early hospital enterance after pheo surg.
- Trial name
- NCT06697652
- Testing
- adrenalectomy
- Volunteers
- 346 people
- Sponsor
- Zagazig University
Laparoscopic Adrenalectomy, Day Surgery
Thoracic Paravertebral Block in Daytime Laparoscopic Partial Adrenalectomy
Day surgery refers to the entire diagnostic and therapeutic process completed within 24-48 h, including patient admission, surgery, and discharge.
- Trial name
- NCT06566521
- Testing
- thoracic paravertebral block
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanxi Bethune Hospital
Adrenalectomy; Status, Obesity, Morbid
Effect of Ketogenic Diet on Peri-operative Complications of Right Laparoscopic Adrenalectomy in Obese Patients
Ketogenic diet is often prescribed to morbid obese patients scheduled for bariatric surgery in order to reduce liver size, thus making surgery less demanding.
- Trial name
- NCT05816031
- Testing
- Ketogenic diet
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Federico II University
Adrenal Tumor, Adrenal Disease
Surgical Treatment of Adrenal Diseases- Laparoscopic vs. Robotic-assisted Adrenalectomy
The goal of this multicenter, observational, analytic, randomized clinical trial is to analyze the laparoscopic and robot-assisted method in the surgical treatment of patients with adrenal diseases.
- Conditions
- Adrenal Tumor, Adrenal Disease, Adrenal Mass, Adrenalectomy; Status
- Trial name
- NCT06050057
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Olomouc
Primary Aldosteronism, Primary Aldosteronism Due to Aldosterone Producing Adenoma
Outcome of Patients With Primary Aldosteronism
Majority of patients with hypertension have primary hypertension (without an underlying cause). Primary aldosteronism (PA) is the most common cause of secondary hypertension, and can be found in 5-10% of patients locally.
- Conditions
- Primary Aldosteronism, Primary Aldosteronism Due to Aldosterone Producing Adenoma, Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral), Adrenalectomy; Status
- Trial name
- PA_Outcome (NCT04428827)
- Testing
- Unilateral adrenalectomy in patients with unilateral disease
- Where
- Singapore
- Volunteers
- 600 people
- Sponsor
- Changi General Hospital
Pain Management, Nerve Block
Transmuscular Quadratus Lumborum Block for Postoperative Pain After Laparoscopic Adrenalectomy
This prospective, randomized control study aims to compare the analgesic effect, satisfaction with anesthesia and analgesia between single-injection QLB (quadratus lumborum block)+general anesthesia (GA) and general anesthesia…
- Conditions
- Pain Management, Nerve Block, Laparoscopic Adrenalectomy
- Trial name
- NCT03942237
- Testing
- single-injection QLB(quadratus lumborum block)
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Peking Union Medical College Hospital
Pain Management, Nerve Block
Quadratus Lumborum Block : Effect on Acute Pain and Quality of Recovery After Laparoscopic Adrenalectomy
This prospective, randomized ,control study aims to compare the analgesic effect,quality of recovery, length of hospital stay ,et al.
- Conditions
- Pain Management, Nerve Block, Laparoscopic Adrenalectomy
- Trial name
- NCT03844477
- Testing
- single-injection QLB(quadratus lumborum block)
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Peking Union Medical College Hospital
Adrenal Gland Metastases, Adrenalectomy
Adrenalectomy for Solitary Adrenal Gland Metastases
The adrenal glands are one of the most common organs involved in metastatic disease. Metastases are the second most common type of adrenal mass, second only to adenomas.
- Trial name
- NCT01135238
- Volunteers
- 168 people
- Sponsor
- Mayo Clinic