Clinical trials: Adult Intensive Care Patients
Intensive Care Unit Patients, Critically Ill Intensive Care Unit Patients
SOFA-2 Score in Turkish ICUs
This study aims to evaluate how well a new scoring system called the Sequential Organ Failure Assessment-2 (SOFA-2) works in adult intensive care units in Türkiye.
- Trial name
- TR-SOFA2 (NCT07338240)
- Where
- Turkey (Türkiye)
- Volunteers
- 5,200 people
- Sponsor
- Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital
Post-Intensive Care Syndrome, Sedation
A Pooled Analysis of Long-Term Outcomes After Inhaled Isoflurane Via the Sedaconda ACD-S Compared to Intravenous Propofol
This pooled analysis will assess Cognitive, Mental Health, Functioning, and Quality of Life Assessments data from the Phase 3 registration studies INSPiRE-ICU 1 (NCT05312385) and INSPiRE-ICU 2 (NCT05327296) to explore potential…
- Trial name
- NCT06809218
- Testing
- Inhaled isoflurane administered by Sedaconda ACD-S, Intravenous infusion of propofol
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- Sedana Medical
Intensive Care Unit Syndrome
Patterns of PTSD in Adult Patients After Intensive Care
This study aims to describe adult patients' patterns of Post-traumatic stress disorder (PTSD) at discharge, 3, and 12 months after intensive care.
- Trial name
- NCT03915977
- Testing
- Post ICU recovery program
- Where
- Denmark
- Volunteers
- 386 people
- Sponsor
- Holbaek Sygehus
Delirium in Old Age, Delirium in the Intensive Care Unit
Multi-Component Delirium Prevention Bundle in Older Cardiac Intensive Care Unit Patients
The goal of this randomized controlled clinical trial is to learn whether a structured delirium prevention protocol can reduce the occurrence of delirium in older adults admitted to the cardiac intensive care unit (CICU).
- Conditions
- Delirium in Old Age, Delirium in the Intensive Care Unit, Delirium Confusional State, Delirium
- Trial name
- CICUDEL (NCT07776184)
- Testing
- Multicomponent Delirium Prevention Bundle, Control Group
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Tel Aviv Medical Center
Ultrasound, Optic Nerve Sheath Diameter
Ultrasound Measurement of Optic Nerve Sheath Diameter as Non-Invasive Detector of Raised Intracranial Pressure in Adult Traumatic and Non-Traumatic Neurocritical Patients in ICU
This study aimed to assess the role of ultrasound as a non-invasive method (bedside) to measure the rise of intracranial pressure by measuring the optic nerve sheath diameter in traumatic and nontraumatic neurocritical patients.
- Conditions
- Ultrasound, Optic Nerve Sheath Diameter, Non-Invasive, Intracranial Pressure
- Trial name
- NCT06993961
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Staphylococcus Aureus
Epidemiological Study of Intestinal Colonization With Staphylococcus Aureus
Nasal colonization with S. aureus is a risk factor for infection with this bacterium. A methodologically well conducted study of S. aureus bacteremia showed that 80% of S.
- Trial name
- DigeSTAPH (NCT02547272)
- Testing
- Nasal and rectal bacterial samples
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
VAP - Ventilator Associated Pneumonia
The Effectiveness of the Modified Bundle in the Prevention of VAP.
Ventilator-associated pneumonia (VAP) is an important cause of prolonged intensive care unit and hospital length of stay, healthcare costs and mortality in mechanically ventilated patients.
- Trial name
- VAP (NCT04038814)
- Testing
- Routine prevention of VAP, Modified prevention of VAP
- Where
- Poland
- Volunteers
- 386 people
- Sponsor
- Andrzej Frycz Modrzewski Krakow University
Critically Ill, Mechanically Ventilated
Treatment of Invasively Ventilated Adults With Early Activity and Mobilisation
The aim of this study is to evaluate the effect of early activity and mobilisation during prolonged IMV on the composite outcome "days alive and out of hospital to day 180".
- Trial name
- TEAM(III) (NCT03133377)
- Testing
- Early activity and mobilisation
- Where
- 49 sites in Australia, Germany and 3 more
- Volunteers
- 750 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Critical Illness
Observational Cohort Study on the Use of Parenteral Nutrition and Clinical Outcomes in Adult Critically Ill Patients
The aim of this study is to characterise the use of clinical nutrition support, especially of parenteral nutrition that is administered directly into a vein, in adult patients with critical illness.
- Trial name
- NCT04143503
- Where
- 76 sites in Austria, Belgium and 9 more
- Volunteers
- 1,208 people
- Sponsor
- Fresenius Kabi
Wounds and Injuries, Mortality
Evaluation of Three Trauma Mortality Scores in Adults Admitted to Intensive Care in Tunisia
The goal of this retrospective observational study is to learn how well three simple trauma scores predict death during the hospital stay in adults admitted to intensive care after an injury in Tunisia.
- Conditions
- Wounds and Injuries, Mortality, Critical Illness
- Trial name
- TICU-SCORES (NCT07848776)
- Testing
- Trauma mortality prediction scores: GAP, MGAP, and T-NTS
- Volunteers
- 1,000 people
- Sponsor
- University Tunis El Manar