Clinical trials: Adults With Overweight and Obesity
Psoriatic Arthritis, Obesity
Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Psoriatic Arthritis and Obesity or Overweight
The main purpose of this study is to demonstrate that when participants with psoriatic arthritis and obesity or overweight in the presence of at least 1 weight-related comorbid condition receive ixekizumab and tirzepatide…
- Trial name
- TOGETHER-PsA (NCT06588296)
- Testing
- Ixekizumab, Tirzepatide
- Where
- 86 sites in United States, Puerto Rico
- Volunteers
- 279 people
- Sponsor
- Eli Lilly and Company
Obesity & Overweight, MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis)
Adherence and Tolerability of Four Very Low-Calorie Ketogenic Diet Approaches in Adults With Obesity or Complicated Overweight
This study, called KOBE Study, looks at how well different very low-calorie ketogenic diets (VLCKD) are followed and tolerated by adults with obesity or complicated overweight in routine clinical practice.
- Conditions
- Obesity & Overweight, MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis), Type 2 Diabetes, Insulin Resistance
- Trial name
- KOBE (NCT07389122)
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- University of Bologna
Obesity, Type 2 Diabetes
Stress, Dietary Lapse and Weight Loss Among Adults With Type 2 Diabetes
A clinical trial that uses personal digital assistants (PDAs) to assist in examining the relationship between self reported stress, an objective biochemical indicator of stress (salivary alpha amylase) and self-reported dietary…
- Trial name
- NCT00831194
- Testing
- Personalized diet plan and PDA self reporting.
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Dyslipidemias, Overweight and Obesity
Nutrigenetic Intervention on Blood Lipid Markers and Body Composition of Adults With Overweight and Obesity
Obesity is defined as the accumulation of excessive fat, attributed to the maintenance of a positive energy imbalance between calorie intake and expenditure.
- Trial name
- NCT05210023
- Testing
- NUTRIGENETIC DIET INTERVENTION, CONVENTIONAL DIET INTERVENTION
- Where
- Mexico
- Volunteers
- 101 people
- Sponsor
- Instituto Tecnológico y de Estudios Superiores de Occidente
Obesity, Overweight
Study of the Effect of Moxonidine and Diet on Sympathetic Functions in Young Adults With Obesity
The prevalence of obesity is increasing rapidly among adults and has more than doubled in the past 10 years. The metabolic syndrome (MS) is often associated with obesity.
- Trial name
- NCT01180231
- Testing
- Moxonidine (Physiotens), Dietary intervention
- Where
- 2 sites in Australia
- Volunteers
- 77 people
- Sponsor
- Baker Heart and Diabetes Institute
Oxidative Stress, Obesity
Acute Effect of Apple Cider Vinegar on Postprandial Plasma Malondialdehyde in Adult With Obesity
Research on the benefits of apple cider vinegar has tended to focus on its hypoglycemic effects and lipid profile changes during long-term consumption, without exploring its acute effects on oxidative stress during short-term…
- Trial name
- NCT07414875
- Testing
- apple cider vinegar
- Where
- Indonesia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Obesity
Resistance and Aerobic Exercise With Nutritional Supplementation in Men and Women
The purpose of this study is to identify the influence of resistance and aerobic exercise with different nutritional supplements in middle-aged men and women on various physiological measures.
- Trial name
- S-017 (NCT00812409)
- Testing
- Whey protein supplementation with exercise, Non protein supplementation with exercise (control)
- Where
- United States
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Purdue University
Diabetes Mellitus, Type 2 Diabetes
Improving Glycemic Control Using a Virtual Weight Control Program and Continuous Glucose Monitoring
This study is a randomized clinical trial with the primary aim examining the efficacy of a novel integrated solution of a digitally delivered behavioral weight management program tailored for diabetes utilizing a continuous…
- Conditions
- Diabetes Mellitus, Type 2 Diabetes, Obesity
- Trial name
- VITAL-CGM (NCT05935514)
- Testing
- WW Intervention, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 152 people
- Sponsor
- Pennington Biomedical Research Center
Obesity, Overweight
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
Study ASC30-301 (AURORA-1) is a Phase III, global, multicenter, randomized, double-blind, placebo-controlled study to investigate the long-term efficacy, safety, and tolerability of three maintenance doses of once-daily oral…
- Conditions
- Obesity, Overweight, Chronic Weight Management
- Trial name
- AURORA-1 (NCT07743463)
- Testing
- ASC30 tablets A1
- Where
- 122 sites in United States, Canada and 5 more
- Volunteers
- 3,003 people
- Sponsor
- Ascletis Pharma (China) Co., Limited
Osteoarthritis of Knee
Clinical Trial to Evaluate Safety and Efficacy of MesoCellA-Ortho Tissue-Engineered Advanced Therapy Product in Patients With Osteoarthrosis and Civilisation Diseases
The aim of the study is to evaluate safety, tolerability and clinical efficacy of a newly developed MesoCellA-Ortho tissue-engineered advanced therapy medicinal product in adult patients suffering with osteoarthritis and…
- Trial name
- BioMiStem-CT (NCT05081921)
- Testing
- MesoCellA-Ortho administration, HA administration
- Where
- Poland
- Volunteers
- 192 people
- Sponsor
- Jagiellonian University
Obesity
Remote Delivery of Weight Management for Adults With IDD
The purpose of this study is to compare different weight loss programs in people with IDD to see which program works better.
- Trial name
- NCT03291509
- Testing
- Video Conference Meetings, In-person Meetings, Enhanced Stop Light Diet
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Kansas Medical Center
Type 1 Diabetes (T1D), Obesity (Disorder)
Vey Low-Energy Ketogenic Therapy in Adults With Type 1 Diabetes and Obesity on Intensive Insulin Therapy Using Advanded Hybrid Closed Loop System
Overweight and obesity are frequent in adults with type 1 diabetes (T1D), with prevalence exceeding 50% in recent studies. Excess weight in T1D is associated with higher cardiometabolic risk and therapeutic challenges, while…
- Trial name
- KET1D (NCT07185555)
- Testing
- VLEKT
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Obese Adults
Evaluation of the Axomove Therapy Medical Device to Facilitate Adapted Physical Activity for Patients With Obesity
Background: Obesity affects 18.1% of adults in France and leads to numerous chronic complications as well as functional limitations (fatigability, dyspnea).
- Trial name
- ON-TRAC (NCT07903025)
- Testing
- Axomove Therapy, Standard multidisciplinary medical care
- Where
- 8 sites in France
- Volunteers
- 184 people
- Sponsor
- Axomove
Satiety, Appetite
A Study of NatureU Burn on Satiety in Healthy Adults
This single-center, single-blind, non-randomized crossover exploratory study evaluated the short-term effects of NatureU Burn on postprandial satiety in healthy adults.
- Conditions
- Satiety, Appetite, Food Intake, Fat Disorder
- Trial name
- NUBURN (NCT07597382)
- Testing
- Glucose Reference Food, NatureU Burn Plus Glucose
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- OmniSolutions Laboratory Holdings Limited
Overweight, Obesity
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with placebo for body weight reduction in participants with overweight or obesity and type 2 diabetes.
- Trial name
- ENLIGHTEN-2 (NCT07282600)
- Testing
- Eloralintide
- Where
- 143 sites in United States, China and 11 more
- Volunteers
- 1,035 people
- Sponsor
- Eli Lilly and Company
Overweight and Obesity
Effect of Spirulina Maxima and Exercise on General Fitness and Blood Lipids in Older Adults
The global older adult population has grown more than any other age group, which could be explained by the decrease of birth rate and increase of life expectancy.
- Trial name
- NCT04658875
- Testing
- Spirulina maxima supplementation, Wash-out, Isoenergetic diet
- Where
- Mexico
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Type 2 Diabetes, Obese
The Effects of the GOLO for Life® Plan With Release Supplement on Glycemic Control and Weight in Overweight and Obese Adults With Prediabetes or Type 2 Diabetes
The objective of this study is to investigate the efficacy and safety of the GOLO for Life® Plan (G4LP) and Release supplementation on glycemic control and weight in overweight and obese adults with Prediabetes or Type 2…
- Conditions
- Type 2 Diabetes, Obese, Overweight, Prediabetes
- Trial name
- NCT05844644
- Testing
- Release
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Golo
Hidradenitis Suppurativa
Efficacy and Safety of Olatorepatide Versus Placebo in Adults With Moderate to Severe Hidradenitis Suppurativa Living With Overweight or Obesity
This study will test an experimental Regeneron drug called olatorepatide ("study drug") to see if it can help treat Hidradenitis Suppurativa (HS).
- Trial name
- NCT07830329
- Testing
- Olatorepatide
- Volunteers
- 300 people
- Sponsor
- Regeneron Pharmaceuticals
Obesity, Hypertension
HealthMatters@24/7 eLearning for People Supporting Adults With Intellectual and Developmental Disabilities
The barriers faced by people with intellectual and developmental disabilities (IDD) begin in their mid to late 20s and often mirror the experiences of older adults (50+) living in the U.S.
- Conditions
- Obesity, Hypertension, Hypercholesterolemia, Hyperglycemia
- Trial name
- HM@24/7 (NCT03206164)
- Testing
- Asynchronous, eLearning Intervention
- Where
- United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Sarcopenic Obesity, Obesity and Overweight
Effectiveness of Different Types of Training in Older Adults With Sarcopenic Obesity
This study is a randomized, parallel-group, double-blind clinical trial. The primary aim is to assess the effectiveness of power-based resistance training, multimodal exercise incorporating non-specific movements, and a control…
- Conditions
- Sarcopenic Obesity, Obesity and Overweight, Sarcopenia
- Trial name
- NCT06895122
- Testing
- High resistance training, Multicomponent Training
- Where
- Spain
- Volunteers
- 33 people
- Sponsor
- University of Salamanca