Clinical trials: Adults Without Disabilities
Asperger's Disorder, Mental Retardation
Cognitive Neuroscience of Autism Spectrum Disorders
Background: Autism spectrum disorders (ASDs) are a group of developmental disorders that affect communication, social interaction, and behavior.
- Conditions
- Asperger's Disorder, Mental Retardation, Children, Adult
- Trial name
- NCT01031407
- Where
- United States
- Volunteers
- 678 people
- Sponsor
- National Institute of Mental Health (NIMH)
Hospital Associated Disability, Immobility
Targeting Muscle Strength Loss Due to Hospitalization in Older Adults by Blood-flow Restriction Combined With an Electromyography-driven Serious Game.
This study investigates a new training method designed to help older adults preserve their muscle strength during hospitalization.
- Conditions
- Hospital Associated Disability, Immobility, Older Adults (65 Years and Older)
- Trial name
- GHOSTLY+ (NCT07294131)
- Testing
- Gamified isometric strength training with blood flow restriction, Standard Physiotherapy
- Where
- 3 sites in Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Adult, Disability
Experience and Understanding of the Mouth, Oral Health and Function Amongst Adults With Disabilities and Complex Health Conditions.
Oral health is the one of the commonest causes of health problems in the world, with almost all individuals suffering from reduced oral health at some stage over their life span.
- Conditions
- Adult, Disability, Chronic Disease, Oral Health
- Trial name
- FAULKS (NCT04815434)
- Testing
- Interview
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Clermont-Ferrand
Migraine, Migraine Disease
Evaluation of the Migraceutics® Phase-Specific Dietary Supplement Regimen on Quality of Life, Work Productivity, and Biomarkers in Adult Migraineurs: The Migraceutics® START Study
The purpose of this study is to evaluate the impact of the Migraceutics® phase-specific dietary supplement regimen on quality of life, work productivity, and biomarkers in adult migraineurs.
- Conditions
- Migraine, Migraine Disease, Migraine Disorder, Migraine Headache
- Trial name
- NCT07634146
- Testing
- Foundational dietary supplement, Luteal phase dietary supplement add-on, Migraine phase dietary supplement add-on
- Where
- United States
- Volunteers
- 920 people
- Sponsor
- Miracle Wellness LLC
Social Isolation in Older Adults, Social Isolation or Loneliness
CAPABLE Care + Connect
In this evaluation scale-up research project, the investigators seek to test an implementation of CAPABLE on the infrastructure of home-based primary care for individuals who may experience social isolation and/or loneliness.
- Conditions
- Social Isolation in Older Adults, Social Isolation or Loneliness, Social Isolation, Quality of Life
- Trial name
- NCT07123298
- Testing
- CAPABLE Care + Connect - Open Label Pilot, CAPABLE Care + Connect - Pilot
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Mobility Disability, Older Adults
Community-based Functional Fitness for Adults Aging With Mobility Disability
Evaluate the feasibility and potential effectiveness of a 12-week, high-intensity functional training (HIFT) intervention on frailty in older adults (60+) with mobility disabilities (MD) who are ambulatory
- Trial name
- AAIMLCOA (NCT07283510)
- Testing
- Functional Fitness
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Adults With Intellectual Disability
"Wai Ji Match Fun" Card Games for People With Intellectual Disabilities
A new set of card game, Wai Ji Match Fun (WJMF), has been developed by Wai Ji Christian Service (WJCS), a non-governmental organization in Hong Kong, specifically designed for individuals with intellectual disabilities (ID).
- Trial name
- NCT07019584
- Testing
- Wai Ji Match Fun card games
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Disabilities Physical, Falls
Adapting, Implementing and Evaluating the Effectiveness of HARP for People With Disabilities
The Home Hazard Removal Program (HARP) is an effective fall prevention intervention program which targets home hazard identification/removal.
- Conditions
- Disabilities Physical, Falls, Fall Prevention, Adults
- Trial name
- HARP3 (NCT07033897)
- Testing
- Adapted HARP
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Washington University School of Medicine
Learning Disability, Adult
Ethnography of Hospital Care for Adults With Learning Disabilities
This study will: 1. explore care experiences during a hospital admission from the perspectives of adults with learning disabilities (including people with profound learning disabilities) and their carers. 2.
- Trial name
- Care4Me (NCT06997250)
- Volunteers
- 96 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Fragile X Syndrome (FXS), Neurotypical Adults
Neural Biomarkers in Fragile X Syndrome
The purpose of this non-interventional test /re-test study is to assess neural biomarkers in adult subjects with Fragile X syndrome compared to those measured in a population of typically developing adults
- Trial name
- EXP-CTH120 (NCT06957054)
- Testing
- Any
- Where
- 2 sites in Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Connecta Therapeutics, S.L.
Learning Disability, Adult, Mental Health
Learning Disability Group Art Therapy: Looking and Asking
A qualitative study of group art therapy in England for adults with a learning disability accessing community services. Different stakeholder views and experiences will be gathered using ethnographically-informed group…
- Trial name
- GATher-LD (NCT05761600)
- Testing
- Ethnographically-informed group observation, Semi-structured Interviews, Focus Group
- Where
- 5 sites in United Kingdom
- Volunteers
- 22 people
- Sponsor
- Queen Mary University of London
Children, Adult, Spastic Cerebral Palsy
Full-spectrum Medical Cannabis for Treatment of Spasticity in Patients With Severe Forms of Cerebral Palsy
The proposed study is a double-blind, placebo-controlled, cross over study on 60 children aged 5 to 25 years with severe spasticity related to cerebral palsy (CP), level IV and V with full-spectrum medical cannabis product of…
- Conditions
- Children, Adult, Spastic Cerebral Palsy, Quality of Life, Cannabis
- Trial name
- HemPhar (NCT04634136)
- Testing
- Lab tests, ECG, Cannabinoid Levels
- Where
- 2 sites in Slovenia
- Volunteers
- 55 people
- Sponsor
- University Medical Centre Ljubljana
Older Adults, ICU
Prognostic Modelling for Prediction of Mortality and Functional Disability in Critically-ill Elderly Patients
Prospective observational study recruiting elderly patients of 60 years and above admitted to Intensive Care Unit (ICU), to study multiple domains of biomarkers ability to predict mortality of patients during intensive care unit…
- Conditions
- Older Adults, ICU, Mortality Prediction, Functional Disability After ICU
- Trial name
- MYELDERLYICU (NCT06163976)
- Where
- 4 sites in Malaysia
- Volunteers
- 329 people
- Sponsor
- Clinical Research Centre, Malaysia
Adults Without Disabilities
Normative Values and Reference Equations of a New Incremental Step Test for the Assessment of Exercise Capacity for Portuguese Adults
According to the official guidelines, a range of settings for cardiorespiratory rehabilitation, including the community- and home-based models, are considered to answer to the inadequate number of rehabilitation services…
- Trial name
- NCT04801979
- Testing
- Incremental Step Test
- Where
- Portugal
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Polytechnic Institute of Porto
Intellectual Disabilities (F70-F79), Problem;Behaviour;Adult
Mental Health and Healthcare in Adults With Intellectual Disabilities
Intellectual disability (ID) is a diagnosis characterized by significant limitations both in intellectual functioning and in adaptive behavior as expressed in conceptual, social and practical adaptive skills.
- Conditions
- Intellectual Disabilities (F70-F79), Problem;Behaviour;Adult, Mental Health Issue, Employment
- Trial name
- NCT05703503
- Where
- Norway
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Organic, Including Symptomatic, Mental Disorders, Substance Use
Exploring the Comorbidity Between Mental Disorders and General Medical Conditions
Mental disorders have been shown to be associated with a number of general medical conditions (also referred to as somatic or physical conditions).
- Conditions
- Organic, Including Symptomatic, Mental Disorders, Substance Use, Schizophrenia, Mood [Affective] Disorders
- Trial name
- COMO-GMC (NCT03847753)
- Testing
- Organic Disorders, Substance Use Disorders, Schizophrenia Disorders
- Volunteers
- 5,940,299 people
- Sponsor
- University of Aarhus
Intellectual Disability, Adolescent Development
Prevention Among Young People With Intellectual Disability
This study aims to evaluate an intervention using the Toolkit "Children - what does it involve?" and the "Real-Care-Baby" (RCB) simulator among students with intellectual disability (ID), using a cluster randomized trial design…
- Conditions
- Intellectual Disability, Adolescent Development, Young Adult
- Trial name
- NCT03348124
- Testing
- "Children - what does it involve?"
- Where
- Sweden
- Volunteers
- 59 people
- Sponsor
- Uppsala University
Mobility Disability, Older Adults
A Multi-Site Trial of the Impact of Assistive Technology With Assistance Users and Their Caregivers
Many individuals with mobility limitations, especially those who are older and have more severe impairments, use a combination of assistive devices and personal assistance to meet their needs.
- Conditions
- Mobility Disability, Older Adults, Community Dwelling
- Trial name
- CATS (NCT01640470)
- Testing
- Assistive Technology Provision and Tune-Up Intervention, Customary Care
- Where
- 3 sites in Canada
- Volunteers
- 240 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal