Clinical trials: Advanced Age
Healthy Subjects
Clinical Trial In Healthy Volunteers And Health Elderly Volunteers To Evaluate The Safety, Tolerability And Blood Concentration After Single And Multiple Escalating Oral Doses Of PF-06751979.
This study will test the safety, tolerability and blood concentrations of single and multiple oral doses of PF-06751979 in health subjects and healthy elderly subjects.
- Trial name
- NCT02793232
- Testing
- PF-06751979 single dose, PF-06751979 multiple ascending dose, PF-06751979 multiple dose
- Where
- Belgium
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Pfizer
Aging Well
Strength Training in Hypoxia to Improve Bone and Cardiovascular Health of Elderly
Due to age-related effects, the bone and cardiovascular health are damaged. Physical exercise and in particular the strength training has been proposed as a fundamental tool to these pathologies, especially in the elderly.
- Trial name
- NCT04281264
- Testing
- Passive Hypoxia, Normoxia Circuit Training with Elastic Bands, Hypoxia Circuit Training with Elastic Bands
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Postural Balance, Fall
Effectiveness of Telerehabilitation in Balance Training Program
The purpose of this study is to assess the effectiveness of telerehabilitation for fall prevention. Participants are randomly assigned to telerehabilitation group or control group.
- Trial name
- NCT06210828
- Testing
- Telerehabilitation, Control
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Sarcopenia, Aged
HIT Training in the Frail Elderly.
This pilot study aims to investigate whether high intensity interval training can result in rapid improvements in physical fitness amongst the frail elderly (over 70 years old).
- Conditions
- Sarcopenia, Aged, Exercise, Preoperative Care
- Trial name
- eHIT (NCT03138265)
- Testing
- HIIT Device: ergometer
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Appetite Loss, Physical Inactivity
APPETITE: Plant Protein and Exercise Solutions for the Prevention of Undernutrition in Older Adults.
The APPETITE Trial aims to investigate the efficacy of innovative plant protein fibre (PPF) products (developed in a previous workpackage) as part of a personalised diet with/out physical activity on appetite and incidence of…
- Conditions
- Appetite Loss, Physical Inactivity, Undernutrition, Anorexia of Aging
- Trial name
- NCT05608707
- Testing
- Physical activity intervention, Personalised nutrition intervention
- Where
- 3 sites in Germany, Ireland and 1 more
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Fall, Mild Cognitive Impairment (MCI)
Digital STEADI Efficacy
The aging of the U.S. population, combined with health care workforce shortages and insufficient access to effective fall prevention and exercise programs, has contributed to a high burden of fall-related injuries in older…
- Conditions
- Fall, Mild Cognitive Impairment (MCI), Aging
- Trial name
- NCT07852650
- Testing
- Digital STEADI-1, STEADI Standard of Care, Digital STEADI-2
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Friendi.fi Corporation
Aged
Effects of the Programme Developed for Sedentary Elderly in the COVID-19 Pandemic: Mobile Interventional Study
The purpose of all these applications is the same: people keep distance and isolate themselves from those in risk groups and patients.
- Trial name
- NCT05110560
- Testing
- "Stay at Home Take a Step Program (SHTSP)"
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Elderly
Strength Training in Nonagenarians
The Health Enhancing Strength Training in Nonagenarians (STRONG) is a randomised control trial to assess the effectiveness of an aerobic and strength training program for improving functional capacity and quality of life in…
- Trial name
- STRONG (NCT00848978)
- Testing
- 8-week aerobic and strength training program
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital General Universitario Gregorio Marañon
Physical Function in Older Adults
Application-Based Personalized Exercise Program in Older Adults
This study aims to evaluate the feasibility, usability, adherence, and potential effects of an application-based personalized multicomponent exercise program in older adults.
- Trial name
- NCT07872176
- Testing
- Application-Based Personalized Multicomponent Exercise Program
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Elderly Subjects
Effects of Brain Stimulation During Nocturnal Sleep on Memory Consolidation in Elderly Healthy Subjects
The beneficial effect of nocturnal sleep on memory consolidation is well-documented in young, healthy subjects. Especially, periods rich in slow-wave sleep (SWS) have shown a memory enhancing effect on hippocampus-dependent…
- Trial name
- NCT01791790
- Testing
- Stimulation
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Functionally Impaired Elderly, Aging
Functional Impairments and Exercise in Older Adults With Low Physical Function,
Aging is associated with a progressive and generalized deterioration of physiologic systems and greater incidence of chronic conditions, which ultimately translates into functional impairment, disability and dependency.
- Trial name
- HANC-Pilot (NCT02051725)
- Testing
- Active life-style intervention
- Where
- Denmark
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Alzheimer Disease
Study Evaluating Safety, Tolerability and Pharmacokinetics of Single and Multiple Dose of SAM-531
The main objectives of this study is to assess the safety and tolerability of ascending single and multiple oral doses of SAM-531 in healthy subjects
- Trial name
- NCT00726115
- Testing
- SAM-531
- Where
- France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Cognitive Impairment
Preoperative Cognitive Screening of Elderly Surgical Patients
The objectives of this pilot study are: 1. to determine whether a short cognitive test battery administered in the preadmission test center can be used to cognitively stratify elderly patients presenting for elective surgical…
- Trial name
- NCT01826825
- Testing
- Cognitive Screen, Mini-Cog
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Hypertension, Aging
Effects of Aquatic Exercise on Post-exercise Hypotension
This is a randomized controlled trial. The present study involves an acute and chronic intervention, which is a water-based exercise (one session: to acute intervention; 12-weeks of aquatic exercise program: to chronic…
- Conditions
- Hypertension, Aging, Obesity
- Trial name
- NCT03403478
- Testing
- LICE, MICE, HIIE
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Effects of Strength Training in Older Adults
The Effects of Low- and High-intensity Resistance Exercise on Force-velocity Characteristics in Older Adults
The purpose of this study is to compare the impact of high- and low-intensity resistance exercise on force-velocity characteristics, muscle mass and inflammatory processes in older adults.
- Trial name
- NCT01707017
- Testing
- Strength training
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Accidental Falls, Fractures
Exercise Intervention to Prevent Fall-related Fractures and Other Injuries : The Ossébo Study
1. Primary objective: to evaluate the effectiveness of a fall prevention exercise program in preventing falls resulting in fractures and other physical traumas. 2.
- Conditions
- Accidental Falls, Fractures, Fall-related Injuries
- Trial name
- Ossébo (NCT00545350)
- Testing
- Fall prevention exercise program
- Where
- 20 sites in France
- Volunteers
- 706 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Aging
Effects of Two Types of Concurrent Training in Functional Performance and Cognitive Function of Older Adults
The goal of this randomized controlled clinical trial is to identify and compare the impacts of traditional concurrent training and concurrent training consisting of strength training combined with dance classes on functional…
- Trial name
- NCT05859243
- Testing
- Traditional concurrent training, Concurrent training consisting of strength training combined with dance classes
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Eduardo Lusa Cadore
Physical Inactivity Frailty
A Digitally Supported Outdoor Physical Activity Intervention for Mildly Frail Older Adults in Hong Kong
The aging population in Hong Kong is projected to reach 36.6% by 2046, with roughly 16.6% of older adults estimated to be mildly frail-a condition linked to higher risks of falls, hospitalization, and mortality.
- Trial name
- NCT07752615
- Testing
- OUTDOOR-FIT, Active Control
- Where
- Hong Kong
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Hearing Impairment, Sensorineural
Auditory Training and Hearing Aid Satisfaction
Although hearing aids are the most common treatment for hearing loss, and have the potential to help seniors stay active and productive, almost 50% of them who receive hearing aids rarely if ever use them, a state of affairs…
- Trial name
- ATandHAs (NCT04230876)
- Testing
- Auditory Brian Training Games/Activities
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Aging, Postural Balance
Tai Chi Intervention for Balance Function in Older Adults: Predictive and Modifying Roles of Circadian Age
This study investigates the effects of a 12-week Tai Chi intervention on balance function in community-dwelling older adults. Participants are randomly assigned to either a Tai Chi exercise group or a health education control…
- Conditions
- Aging, Postural Balance, Accidental Falls
- Trial name
- NCT07567976
- Testing
- Tai Chi Exercise, Health Education
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zhide Liang
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