Clinical trials: Advanced Age
Diabetes Mellitus, Type 2, Hypercholesterolemia
Single Oral Dose of BeneFlax to Healthy Young and Older Adults
This study is being done to look at age differences in the way the investigators bodies break down a compound found in flax seed (secoisolariciresinol diglucoside or SDG).
- Trial name
- SOD (NCT01531569)
- Testing
- BeneFlax - 38% secoisolariciresinol diglucoside (SDG)
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Aging, Cognitive Function
Efficacy of Computer-Based Cognitive Game Training for Healthy Elderly
The declination on cognitive and motor functions in older adults increases the difficulty to achieve successful aging. Previous studies had reported that contrast to the traditional cognitive training methods, computer cognitive…
- Trial name
- NCT03940079
- Testing
- computer-based cognitive game (including 3 training tasks)
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Dehydrated, Water-Electrolyte Imbalance, Malnutrition, Dehydration (Physiology)
Effects of Increased Water Intake on Hormonal Response, Hydration Status, and Physical Function in Low-drinking Older Adults
DrinkAge is a randomized controlled trial investigating whether increasing daily water intake can improve hydration and health-related outcomes in adults aged 60 years or older who habitually drink relatively little water.
- Trial name
- DrinkAge (NCT07892742)
- Testing
- Water
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Polytechnic University of Santarém
Chronic Obstructive Pulmonary Disease (COPD)
Improvement in COPD Elderly Patients Health: Study Protocol
Guidelines development, their implementation and the physicians' adherence may have an impact on the occurrence of Chronic Obstructive Pulmonary Disease (COPD) exacerbations and patient's quality of life.
- Trial name
- NCT04301505
- Testing
- Intervention 1, Intervention 2
- Where
- Poland
- Volunteers
- 2,520 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Wellness Programs, Hospitalization
The Effectiveness of Peer-to-Peer Community Support to Promote Aging in Place
The investigators' overall objective is to evaluate the effectiveness of peer-to-peer support programs in preventing the necessity of acute health care and nursing home services for older adult populations and in promoting their…
- Conditions
- Wellness Programs, Hospitalization, Emergency Room
- Trial name
- NCT02308696
- Testing
- Peer-to-Peer Support, Standard Community Services
- Where
- 5 sites in United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Aging, Primary Hypothyroidism
Evaluation of Evening Versus Morning Levothyroxine Intake in Elderly
A study designed to compare evening versus morning levothyroxine intake in the elderly.
- Conditions
- Aging, Primary Hypothyroidism, Interaction Drug Food
- Trial name
- MONIALE (NCT03614988)
- Testing
- Evening Levothyroxine Administration, Morning Levothyroxine Administration
- Where
- Brazil
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Geriatric, Elderly
Comparison of Hand Grip Strength in Different Shoulder Positions in Geriatric Individuals: Position-Dependent Strength Analysis
The aim of this study is to examine the relationship between hand grip strength, measured in different shoulder positions, and upper extremity muscle strength, and to reveal the clinical significance of position-dependent…
- Trial name
- NCT07562854
- Testing
- Muscle Strenght Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Avian Influenza
H7N9 Mix and Match With MF59 in Healthy Elderly Persons
This is a Phase II randomized, partially-blinded, controlled trial in 360 (up to 600) males and females, 65 years of age and older, who are in good health and meet all eligibility criteria.
- Trial name
- NCT02213354
- Testing
- MF59, Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013
- Where
- 10 sites in United States
- Volunteers
- 479 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Older Adults, Aging Well
Self-Adaptive Immersive Virtual Reality Serious Game to Enhance Motor Skill Learning and Attention in Older Adults
While scientific evidence emphasizes the detrimental effect of sedentary behavior on health, the literature suggests that, on average, older adults spend 75% of their days in a sedentary manner, and often isolated (Petrusevski…
- Conditions
- Older Adults, Aging Well, Aging
- Trial name
- SAVinGs (NCT06141642)
- Testing
- Self-adaptive serious game, Non-adaptive serious game
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Laval University
Depression
The Effect of a Selective Serotonin Reuptake Inhibitor on Gait, Balance, and Bone Metabolism in Older Adults
The purpose of this study is to examine the effects of sertraline treatment of depression in older adults on gait stability, balance recovery reactions, and markers of bone metabolism.
- Trial name
- NCT02228005
- Testing
- Sertraline
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Aging
Physical Activity for Improving Quality of Life and Reducing Frailty in Advanced Age
Individuals of advanced age undergo both physical and cognitive deterioration. The aim of this study is to explore the connection between level of physical activity and health parameters, quality of life, and frailty.
- Trial name
- NCT01867112
- Testing
- Physical Activity
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Healthy Older Adults
tDCS Effects on Associative Learning in Older Adults of Working Age
The aim of this study is to investigate whether a tDCS-accompanied training of audio-visual associative memory leads to a performance improvement in healthy older individuals.
- Trial name
- TRAINSTIM2 (NCT02795702)
- Testing
- tDCS, training
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Pneumonia, Aging
Genomics and Epigenomics of the Elderly Response to Pneumococcal Vaccines
This is a prospective, single-site, randomized, then open-label study designed to develop a detailed transcriptional and epigenetic profile of the immune response to pneumococcal vaccination with conjugated and non-conjugated…
- Trial name
- NCT03104075
- Testing
- Pneumococcal 13valent Conj Vaccine Diphtheria CRM197 Protein, Pneumococcal Vaccine Polyvalent
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Jackson Laboratory
Behavior, Health
Elderly Health Promotion and Physical Activity
Nurses have an important place in establishing health promotion practices and policies for the elderly to help older adults manage their lifestyles.
- Trial name
- NCT05421481
- Testing
- home visit, health education, mobile application, group walk, message
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Respiratory Syncytial Virus Infections
A Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a COVID-19 mRNA Vaccine in Adults Aged 50 Years and Above
This study is assessing the immunogenicity, safety and reactogenicity of the RSVPreF3 OA investigational vaccine when it is co-administered with a COVID-19 messenger ribonucleic acid (mRNA) vaccine (Omicron XBB.1.5), compared to…
- Trial name
- NCT06374394
- Testing
- RSVPreF3 OA investigational vaccine, COVID-19 mRNA vaccine
- Where
- 24 sites in United States, Belgium and 2 more
- Volunteers
- 841 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Adult Subjects, Healthy Elderly Subjects
Multiple Dose Study Of BIIB118 (PF-05251749) In Healthy Volunteers
This is the first clinical trial to evaluate ascending multiple oral doses in healthy adult and healthy elderly subjects to characterize the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of BIIB118
- Trial name
- NCT02691702
- Testing
- BIIB118, Melatonin
- Where
- 2 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Biogen
Frail Elderly
Increasing the Winter Community Participation of Older Adult Wheelchair Users
The purpose of this study is to examine whether intervention strategies targeted at the level of the environment (e.g. improving access to community based leisure groups, transportation) can successfully promote the community…
- Trial name
- NCT02622828
- Testing
- Participant-identified community based activity
- Where
- Canada
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hyperglycemia
Resistant Starch on Glycemic Response in Older Adults
The purpose of this study was to determine how blood glucose changes after eating energy bars containing resistant starch type 4 compared with bars made with puffed wheat in healthy older adults.
- Trial name
- NCT00676767
- Testing
- Resistant Starch Type 4, Dextrose, Puffed wheat
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Fall Prevention
Pilot Feasibility Study of a Fall Prevention Exercise Programme for Community-dwelling Older Adults in Nanchang, China
The goal of this pilot clinical trial is to evaluate the feasibility of a fall prevention exercise programme for older adults living in urban communities in China.
- Trial name
- NCT07341802
- Testing
- Safe & Joyful Walk, Tai Chi
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Healthy Older Adults
tDCS Effects on GABA Concentration and Brain Functional Connectivity in Older Adults Of Working Age
The aim of this study is to investigate whether anodal tDCS over the left M1 leads to a decrease of GABA concentration and alterations of functional brain connectivity in older people, compared to sham tDCS.
- Trial name
- TRAINSTIM1 (NCT02794272)
- Testing
- tDCS
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
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