Clinical trials: Aetiology
Diarrhoea
Causes of Rotavirus Vaccine Failure in Zambian Children
Zambia recently introduced routine infant immunization against rotavirus - the most important cause of severe gastroenteritis and diarrhoea mortality in children.
- Trial name
- NCT01886833
- Where
- Zambia
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
Multiple Myeloma
Etiology of Multiple Myeloma: A Case-Control Study
Objectives: The overall objective of this project is to identify risk factors associated with the development of multiple myeloma (MM) by integrating epidemiologic, clinical and molecular information.
- Trial name
- NCT00505999
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Lidocaine, Injection Pain
Median Effective Dose of Lidocaine for the Prevention of Pain Caused by the Injection of Propofol Formulated With Medium-/Long-chain Triglycerides
Propofol is widely used in general anesthesia induction, but the occurrence of peripheral intravenous pain is relatively high, causing anxiety, fear and other adverse emotions in patients , aggravating the stress response, and…
- Trial name
- NCT04008433
- Testing
- Lidocaine
- Where
- China
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Shivering Caused by Spinal Anesthesia
COMPARISON OF INTRAVENOUS DEXMEDETOMEDINE AND TRAMADOL FOR POST OPERATIVE SHIVERING AFTER SPINAL ANESTHESIA FOR CAESAREAN SECTION
To compare the mean time of cessation of post-operative shivering after receiving intravenous dexmedetomidine versus tramadol in patients undergoing caesarean delivery under spinal anaesthesia.
- Trial name
- NCT07332572
- Testing
- Tramadol, Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Liaquat National Hospital & Medical College
HPV in Testis Tissue
HPV as a Possible Cause of Azoospermia
Azoospermia is found in 5-20% of all men suffering from infertility, and in more than 20% azoospermia remains unexplained. The investigators suggest, that HPV may be an etiological factor in azoospermia and reduced sperm…
- Trial name
- NCT02329275
- Testing
- Testicular biopsy
- Where
- Denmark
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Dry Eye Syndrome
Comparing the Quality of Topical Autologous Serum in Different Etiologies of Dry Eye Syndrome
Human autologous serum is commonly used in the treatment of dry eye disease. However, different patients may have different effect with autologous serum treatment.
- Trial name
- NCT02774707
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Post-operative Pain
Temperature Rise Caused by Short or Long-wavelengths
Red light has been shown to be less harmful than blue light in vitro and in vivo. Although red light has been already introduced in the market and is currently being used in patients for several reasons, no data exist on the use…
- Trial name
- NCT06418958
- Testing
- Red Light, Blue Light
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Florida
Endometriosis, Pelvic Pain
The Safety and Effectiveness of Surgery With or Without Raloxifene for the Treatment of Pelvic Pain Caused by Endometriosis
Many women with lower abdominal pain have endometriosis. Endometriosis is a condition in which the lining of the uterus (endometrium) is found outside of the uterus. The diagnosis of endometriosis is usually made at surgery.
- Trial name
- NCT00001848
- Testing
- Raloxifene
- Where
- United States
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Impacted Third Molar Tooth
Changes in Resistome After Dental Extraction and Amoxicillin.
The aim of this study is to evaluate the nature of the change in oral and gut bacterial resistance profiles after antibiotic therapy for a surgical procedure in two groups.
- Trial name
- NCT02830347
- Testing
- Amoxicillin, Extraction
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Anemia
Etiology of Anemia Among Preschool Children in Ethiopia
This study aims to determine the etiology of anemia among preschool children in selected regions of Ethiopia. The study is a longitudinal observational study to assess the determinant factors of anemia in two different seasons.
- Trial name
- NCT05626647
- Where
- Ethiopia
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Postoperative Bacteriuria
Does Straight Catheterization in Short Gynecologic Procedures Cause Bacteriuria?
This is a prospective randomized controlled trial to look into the reduction of catheter associated urinary tract infections in the postoperative period.
- Trial name
- NCT01926756
- Testing
- Straight catheterization, No straight catheterization
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Abington Memorial Hospital
Autism, Developmental Disabilities
Childhood Autism Risks From Genetics and the Environment (The CHARGE Study)
The purpose of this study is to understand how genes, environment, and the interplay between the two, influences the development of autism and other neurodevelopmental disorders.
- Trial name
- NCT00106652
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Calcific Aortic Stenosis, Calcific Aortic Stenosis - Bicuspid Valve
Identification of Genetic Causes of Calcific Aortic Valve Disease
This study aims to identify the molecular genetic causes of the variability in development of calcific aortic valve disease in bicuspid and tricuspid aortic valves and their associated aortic dilation.
- Conditions
- Calcific Aortic Stenosis, Calcific Aortic Stenosis - Bicuspid Valve, Aortic Valve Disease, Aortic Valve Calcification
- Trial name
- NCT04149600
- Testing
- Patients scheduled to undergo aortic valve replacement or aortic surgery at BIDMC will be approached for participation in this study.
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Donors Safety
Causes of Disqualification of Egyptian Potential Living Liver Donors
Due to absence of Deceased-donors in Egypt, Living-donor liver transplantation (LDLT) has emerged as an option to the traditional deceased-donor transplantation procedure.
- Trial name
- NCT01809249
- Where
- Egypt
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Influenza Caused by the Novel A(H1N1)v Influenza Virus
Evaluation of Pandemic Vaccination Campaign
A cohort of 4000 community-dwelling adults is followed to evaluate the effectiveness of the Finnish national A(H1N1)v influenza vaccination campaign in preventing the first episode of laboratory-confirmed A(H1N1)v influenza.
- Trial name
- NCT01024725
- Testing
- Follow-up
- Where
- Finland
- Volunteers
- 3,518 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Back Pain, Intervertebral Disc Degeneration
The Role of Disc Nutrition in the Etiology and Clinical Treatment of Disc Degeneration
The purpose of this research study is to examine the effects of physical therapy on the spinal discs. Back pain is the number one cause of disability in the US, and the spine is the most common location of chronic pain in…
- Trial name
- NCT04134910
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Suicide, Fatal Suicide
Case Control Psychological Autopsy of Suicide
Suicide is a leading cause of death worldwide, and identifying risk factors has been considered as the key initiative of suicide prevention.
- Conditions
- Suicide, Fatal Suicide, Non Fatal Suicidal Behavior
- Trial name
- NCT05097690
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tamkeen Saleem
Erectile Dysfunction, Metabolic Syndrome
The Incidence and Treatment of Insulin Resistance Among Men With Erectile Dysfunction
Determine if men with erectile dysfunction (ED) are more likely to have insulin resistance compared to healthy controls.
- Conditions
- Erectile Dysfunction, Metabolic Syndrome, Insulin Resistance
- Trial name
- NCT00284960
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
COVID-19 Virus Disease
Study to Evaluate the Safety and Concentrations of Monoclonal Antibody Against Virus That Causes COVID-19 Disease.
A Phase I dose-escalation study to test a new monoclonal antibody (called MAD0004J08) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19 disease.
- Trial name
- MAD0004J08 (NCT04932850)
- Testing
- MAD0004J08
- Where
- 2 sites in Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Toscana Life Sciences Sviluppo s.r.l.
Cushing Syndrome
Quality of Life, Fatigue and Cognitive, Affective and Emotional Dysfunction in Patients With Cushing's Syndrome
This is a prospective, multi-center, case-control study where neurocognitive function will be evaluated in 36 patients with Cushing syndrome (CS) and 36 controls matched for age, gender and education.
- Trial name
- NCT03211624
- Where
- 3 sites in Netherlands, Spain and 1 more
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Göteborg University