Clinical trials: Aetiology
Interstitial Lung Diseases
Nanoparticles Analysis in Lung and Bronchi During Various Pulmonary Interstitial Diseases and Relationships With Their Aetiology
Nanoparticles (NP) are particles whose length, width and height are less than 100 nanometres. Over the past decade, industrial applications of NP have increased dramatically.
- Trial name
- NANOPI (NCT02549248)
- Testing
- BAL, BW, EAC
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Neuroblastoma
Genetic Susceptibility Biomarkers in Children With Neuroblastoma (Also Known as Neuroblastoma Epidemiology in North America [NENA])
This research trial studies the genes biomarkers in children with neuroblastoma. Studying the genes in a child's cancer cells may help doctors improve ways to diagnose and treat children with neuroblastoma.
- Trial name
- NCT01119560
- Testing
- Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis, Questionnaire Administration
- Where
- 153 sites in United States, Canada
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- Children's Oncology Group
Bacteremia
Exposure to Antibiotics and Incidence of Bacteraemia Caused by Resistant Bacteria
The primary objective of the study is to identify the risk factors of community-acquired bacteremia to resistant bacteria. As the secondary objectives, the study aims to describe the episodes of epidemiology of bacteremia…
- Trial name
- BactHub (NCT04065750)
- Volunteers
- 45,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Uterine Inertia, Dystocia
LXRs, Cholesterol Metabolism and Uterine Dystocia
Despite the fact that a link between cholesterol and the myometrium has been clearly established, no study investigating aspects of cholesterol metabolism and uterine dystocia currently exists.
- Trial name
- NCT01107158
- Testing
- Whole blood sampling
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Infants Aged One Month to 2 Years , Infants With Any Type of Feeding (Breast or Artificial or Weaned Attend Assiut University Children Hospital )
Causes and Underlying Factors of Faltering Growth Among Infants
to research in the different causes of failure to thrive in children including organic and non organic causes
- Trial name
- NCT03283215
- Testing
- complete blood count , electrolytes
- Volunteers
- 100 people
- Sponsor
- Assiut University
Suicide, Fatal Suicide
Case Control Psychological Autopsy of Suicide
Suicide is a leading cause of death worldwide, and identifying risk factors has been considered as the key initiative of suicide prevention.
- Conditions
- Suicide, Fatal Suicide, Non Fatal Suicidal Behavior
- Trial name
- NCT05097690
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tamkeen Saleem
Dry Eye Disease
Diurnal Variation in Tear Osmolarity
The purpose of this study is to measure the change in Tear Osmolarity during the course of the day to support clinical diagnosis of aqueous deficiency or meibomian gland disease and differentiate between the two forms of dry eye.
- Trial name
- NCT01321424
- Where
- 6 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ophthalmic Consultants of Long Island
Improve Quality of Life, Heavy Menstrual Bleeding
Treatment of Heavy and/or Prolonged Menstrual Bleeding Without Organic Cause
Abnormal uterine bleeding encompasses abnormalities in the regularity, duration of flow, frequency, and/or blood flow volume relative to normal menstruation.
- Trial name
- NCT02943655
- Testing
- combined contraceptive pills (microcept), medroxyprogesterone acetate (progest), mefenamic acid (ponstan forte)
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- Assiut University
Occupational Diseases
Apps to Reduce the Impact That Adverse Events Among Health Professionals
Adverse events are also the cause of suffering in health professionals involved (second victims). This study has the aim of design and evaluates two applications for staff of hospital and primary care settings with the intention…
- Trial name
- ASV (NCT02410408)
- Testing
- Apps Root Cause Analysis or patient safety ISO certification, information package
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Fever of Unknown Origin
Causes of FUO in Infants and Children
Definition: fever < 38˚c for which the cause could not be identified, documented by a health care provider after 3w.evaluation as an outpatient [or after 1w. evaluation in the hospital].
- Trial name
- NCT04073108
- Testing
- tuberculin test
- Volunteers
- 50 people
- Sponsor
- Assiut University
Brain Infarction, Ischemic Stroke
Searching for Explanations for Cryptogenic Stroke in the Young: Revealing the Etiology, Triggers, and Outcome
BACKGROUND: In industrialized countries a considerable and increasing proportion of strokes occur at younger ages. Stroke at young age causes marked disability at worst and thus long-standing socioeconomic consequences and…
- Conditions
- Brain Infarction, Ischemic Stroke, Thrombosis, Foramen Ovale, Patent
- Trial name
- SECRETO (NCT01934725)
- Where
- 19 sites in Estonia, Finland and 11 more
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- SECRETO Study Consortium
Complications of Surgical and Medical Care: General Terms, Adverse Reaction to Drug
The Thai Surgical Intensive Care Study (Thai-SICU Study)
The study observed the 28 days mortality of 9 participated University base surgical intensive care unit (SICU) as well as the occurrence of adverse events in SICU.
- Conditions
- Complications of Surgical and Medical Care: General Terms, Adverse Reaction to Drug, Sequelae of External Causes of Morbidity and Mortality, Critical Illness
- Trial name
- THAI-SICU (NCT01354197)
- Where
- 9 sites in Thailand
- Volunteers
- 4,652 people
- Sponsor
- Royal College of Anesthesiologists of Thailand
Chronic Heart Failure
Left Atrial Distensibility Guiding Management in Advanced Chronic Heart Failure
Background and Purpose- According to our prior studies, left atrial (LA) distensibility was associated significantly with left ventricular filling pressure in patients with acute myocardial infarction (AMI), chronic stable…
- Trial name
- NCT01307722
- Testing
- left atrial distensibility-guiding prescription of heart failure drugs
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Kaohsiung Veterans General Hospital.
COVID-19
Effectiveness of Inactivated COVID-19 Vaccine of the First Booster Dose
This is a retrospective test-negative case-control study of COVID-19 Vaccine (CoronaVac®) manufactured by Sinovac Research and Development Co., Ltd.The main purpose of this study is to measure vaccine effectiveness of homologous…
- Trial name
- NCT05367895
- Testing
- COVID-19 Vaccine (Vero Cell), Inactivated
- Where
- Brazil
- Volunteers
- 14,000 people, healthy volunteers welcome
- Sponsor
- Sinovac Research and Development Co., Ltd.
Financial Stress, Economic Problems
The IGNITE for Kids Study on Concentrated Investment in Black Neighborhoods and Child Health and Well-Being
Black children and adults in the United States fare worse across nearly every health indicator compared to White individuals. In Philadelphia, the location of this study, these health disparities result in a stark longevity gap…
- Conditions
- Financial Stress, Economic Problems, Environmental Exposure, Health Behavior
- Trial name
- NCT05760001
- Testing
- Assigned Interventions
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- University of Pennsylvania
Sciatica, Radiating Pain
The Effect of Early MSAT Treatment on Sciatica Caused by Traffic Accidents.
The investigators would like to conduct a pilot study prior to a practical randomized control study on the effectiveness of initial MSAT treatment on inpatients complaining of radiating pain and abnormal sensation in the lower…
- Conditions
- Sciatica, Radiating Pain, Paresthesia, Dysesthesia
- Trial name
- NCT06179901
- Testing
- Integrative Korean Medicine Treatment, lower limb motion style acupuncture treatment
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Jaseng Medical Foundation
Osteomyelitis, Pseudomonas Infections
Monotherapy vs Combination Therapy for Bone Infections Caused by Pseudomonas Aeruginosa
This study looks at how well one antibiotic (monotherapy) works compared to two antibiotics (combination therapy) in treating bone infections caused by Pseudomonas aeruginosa.
- Conditions
- Osteomyelitis, Pseudomonas Infections, Pseudomonas Aeruginosa, Bacterial Infections
- Trial name
- NCT07056881
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Coronary Artery Disease, Atrial Fibrillation
Rivaroxaban Estimation With Warfarin in Atrial Fibrillation Patients With Coronary Stent Implantation Study (REWRAPS)
Antiplatelet therapy is indispensable for the prevention of stent thrombosis in patients who underwent coronary artery stenting.
- Conditions
- Coronary Artery Disease, Atrial Fibrillation, Stroke, Fetal Blood Loss
- Trial name
- REWRAPS (NCT02024230)
- Testing
- Rivaroxaban or Warfarin
- Where
- Japan
- Volunteers
- 500 people
- Sponsor
- Fujita Health University
Medium-chain Acyl-CoA Dehydrogenase Deficiency
Study of Sodium Phenylbutyrate (ACER-001) for the Treatment of Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)
This is a medical research study to test a medication in patients 10 years of age and older with a disease called medium-chain acyl-CoA dehydrogenase deficiency (MCADD) caused by the common ACADM c.985 A>G (K304E) mutation.
- Trial name
- NCT06069375
- Testing
- Sodium phenylbutyrate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Jerry Vockley, MD, PhD
Colorectal Cancer, Metastatic Cancer
Combination Chemotherapy With or Without Cetuximab Before and After Surgery in Treating Patients With Resectable Liver Metastases Caused By Colorectal Cancer
RATIONALE: Drugs used in chemotherapy, such as oxaliplatin, fluorouracil, leucovorin, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00482222
- Testing
- cetuximab, capecitabine, fluorouracil
- Where
- 22 sites in United Kingdom
- Volunteers
- 340 people
- Sponsor
- University of Southampton
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