Clinical trials: Aetiology
Neonatal Hypoglycemia, Metabolic Disease
Pattern of Metabolic Causes of Neonatal Hypoglycemia
Inborn errors of metabolism (IEM) are disorders in which there is a block at some point in the normal metabolic pathway caused by a genetic defect of a specific enzyme.
- Trial name
- NCT05977972
- Volunteers
- 100 people
- Sponsor
- Assiut University
Covid19, COVID-19 Pneumonia
Clinical Impact of COVID-19 by P.1 SARS-CoV-2 Lineage
Since the first report of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern (VOC) P.1 in Manaus, Brazil, a rapid spread of this lineage across the country has been observed.
- Conditions
- Covid19, COVID-19 Pneumonia, SARS-CoV-2 Infection
- Trial name
- NCT04928469
- Testing
- No intervention performed
- Where
- Brazil
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Lung Diseases
Diagnostic Value of Chest Ultrasound in Pediatrics Lung Diseases
To evaluate the accuracy of chest ultrasound for diagnosis of different lung lesions in comparison to the gold standard among children.
- Trial name
- NCT04326972
- Testing
- ultrasound
- Volunteers
- 50 people
- Sponsor
- Assiut University
Viral Infections, Bacterial Infections
Emergency PWAS in Respiratory Infectious Disease
Develop an emergency PanorOmics Wide Association Study (ePWAS) for the early, rapid biological and pathophysiological characterisation of known and novel Infectious Diseases in adult patients presenting to emergency departments…
- Conditions
- Viral Infections, Bacterial Infections, Fungal Infections, Mixed Infection
- Trial name
- NCT05336851
- Testing
- Biomarker blood draw and saliva collection
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Out-Of-Hospital Cardiac Arrest
Systemic Evaluation of the Etiologies of Young Adults With Non-traumatic Out-of-hospital Cardiac Arrest
The goal of this observational study is to establish the protocol of systemic analysis of the causes of non-traumatic cardiac arrest in young patients.
- Trial name
- NCT06122337
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Evans Syndrome
Autoimmune Cytopenia: Genetics and Pathophysiological Mechanism in Pediatric Evans Syndrome
Characterization of the genetic causes, and of the immunopathological clinical and biological manifestations in children with pediatric Evans syndrome included in a prospective national observational cohort of rare diseases.
- Trial name
- ACTION (NCT03912129)
- Testing
- blood sample
- Where
- France
- Volunteers
- 374 people
- Sponsor
- University Hospital, Bordeaux
Nausea, Vomiting
Ginger in Treating Nausea in Patients Receiving Chemotherapy for Cancer
RATIONALE: Ginger may help reduce or prevent nausea. It is not yet known if antiemetic drugs are more effective with or without ginger in treating nausea caused by chemotherapy.
- Trial name
- NCT00040742
- Testing
- ginger
- Where
- 19 sites in United States
- Volunteers
- 745 people
- Sponsor
- Gary Morrow
Aneurysmal Subarachnoid Hemorrhage
Clinical Research Study With Clazosentan to Evaluate Its Effects on Preventing Complications Due to the Narrowing of the Blood Vessels (Vasospasm) in the Brain, Caused by Bleeding Onto the Surface of the Brain
This study will evaluate if clazosentan (on top of normal routine medical care) can reduce the risk of developing complications related to cerebral vasospasm and permanent brain damage as compared to normal routine medical care…
- Trial name
- REACT (NCT03585270)
- Testing
- Clazosentan
- Where
- 80 sites in United States, Austria and 13 more
- Volunteers
- 409 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Venous Ulcer, Arterial Ulcer
PluroGel on Wounds of Mixed Etiology
A randomized controlled study (RCT) to investigate the topical effectiveness of PluroGel in healing venous and mixed aetiology leg ulcers.
- Trial name
- NCT03275831
- Testing
- PluroGel, Intrasite gel
- Where
- 2 sites in United Kingdom
- Volunteers
- 16 people
- Sponsor
- Medline Industries
Ventilator Associated Pneumonia
Microbial Etiology of Ventilator-associated Pneumonia in COVID-19 Infected Patients
National multicentric observational retrospective case-control study comparing the relative frequency of the various microorganisms responsible for VAP in patients infected or not by SARS-CoV-2 and their resistance to antibiotics.
- Trial name
- NCT04344509
- Testing
- Bacterial species isolated
- Volunteers
- 10,000 people
- Sponsor
- Poitiers University Hospital
Out-Of-Hospital Cardiac Arrest, Pediatric Disorder
Etiology, Incidence and Survival of Pediatric Out-of-hospital Cardiac Arrests: a Four-year Danish Analysis
Background: OHCA is a rare condition for children and young adults. Overall incidence rates are reported as 3.3-5.97 per 100.000 inhabitants.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Pediatric Disorder, Cardiopulmonary Arrest
- Trial name
- Child-OHCA (NCT04275856)
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Stroke
Micro-embolic Signals Detection With Transcranial HOLter in Acute Ischemic STroke
In acute ischemic stroke, the identification of an etiology is of major importance to prevent recurrence by providing the best treatment.
- Trial name
- HOLISTER (NCT02762552)
- Testing
- Transcranial-holter monitoring
- Where
- France
- Volunteers
- 244 people
- Sponsor
- University Hospital, Bordeaux
Cervical Spondylosis
Yoga Chikitsa for Neck Pain Caused by Cervical Spondylosis
Neck Pain caused by Cervical spondylosis (CS) is one of the most common health complaints. Despite its frequency as clinical problem worldwide, there are few evidence-based studies that document efficacy of therapies for neck…
- Trial name
- NCT03526965
- Testing
- Yoga Chikitsa, Usual care
- Where
- India
- Volunteers
- 117 people
- Sponsor
- NMP Medical Research Institute
Failure of Cervical Dilatation, Complications; Cesarean Section
Is Routine Cervical Dilatation Necessary During Elective Caesarean Section? A Randomised Controlled Trial
The purpose of this prospective randomised study was to determine the effect of routine cervical dilatation during elective caesarean section on maternal morbidity
- Conditions
- Failure of Cervical Dilatation, Complications; Cesarean Section, Wound Infection,, External Causes of Morbidity and Mortality
- Trial name
- NCT01954719
- Testing
- cervix dilated after surgery, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
ISCHEMIC CARDIOMYOPATHY
Clinical Trial of Manganese-Enhanced MRI (MEMRI) to Assess Peri-Infarct Injury
The purpose of this study is to evaluate the safety and tolerance of a new intravenous diagnostic agent, SeeMore or EVP 1001-1, in patients with Cardiovascular Disease (MEMRI scan).
- Trial name
- NCT02933034
- Testing
- Manganese-enhanced MRI contrast reagent, Gadolinium-enhanced MRI contrast reagent
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Stanford University
Skin Ulcer Venous Stasis Chronic, Mixed Arteriovenous Leg Ulcer
Pilot Study Comparing NatroxTM Topical Oxygen Therapy to A Placebo in the Management of Non-Healing Leg Ulcers
The purpose of this study is to determine the effectiveness of the NatroxTM Topical Oxygen device versus a placebo in patients with non-healing leg ulceration in conjunction with standard best practice.
- Trial name
- NCT01913704
- Testing
- NatroxTM Device
- Where
- 2 sites in Czechia
- Sponsor
- Inotec AMD Limited
Anemia, Aplastic, Blood Disease
Etiology of Blood Dyscrasias: Analysis of the International Agranulocytosis and Aplastic Anemia Study Data
To quantify the role of drugs and other factors in the etiology of agranulocytosis and aplastic anemia.
- Conditions
- Anemia, Aplastic, Blood Disease, Agranulocytosis
- Trial name
- NCT00005307
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Shoulder Pain
The Efficacy and Safety of Shoulder Chuna on in Patients With Shoulder Pain Caused by Traffic Accidents
This study is a double blind, randomized controlled trail. condition/disease: Patient with acute shoulder pain and restricted movement due to a traffic accident.
- Trial name
- Shoulder chuna (NCT06624800)
- Testing
- Shoulder chuna treatment(posterior displacement, anterior displacement, or lateral displacement), Korean medical treatment
- Where
- South Korea
- Volunteers
- 98 people
- Sponsor
- Jaseng Medical Foundation
Neurodegeneration With Brain Iron Accumulation (NBIA)
Testing of NBIA Genes: Analysis of Genetic Heterogeneity and Validation of Mitochondrial Markers for Assessing Causality of Sequence Variants.
Neurodegeneration with brain iron accumulation (NBIA) represent a group of rare neurodevelopmental diseases, genetically as well as phenotypically heterogeneous. The diagnosis is based on brain MRI.
- Trial name
- NBIA MITO (NCT05615571)
- Testing
- Establishment of mitochondrial markers, Sequencing tests
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Bordeaux
Degenerative Disc Disease
Comparison of IDD Therapy and Non-surgical Treatment for Low Back Pain Caused by Degenerative Disc Disease
This study is looking at a new machine called the Accu-Spina which administers internal disc decompression by following a computer program.
- Trial name
- NCT00165893
- Testing
- Accu-Spina Device/IDD therapy, Physical Therapy
- Volunteers
- 50 people
- Sponsor
- Emory University
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