Clinical trials: Age Problems
Obesity, Aging
Metabolic Control of Aging and Disease - the MetAGE Deep Phenotyping Cohort
The goal of this prospective observational study is to identify and validate blood based aging biomarkers in relation to cardiometabolic phenotypes of young and old, female and male subjects with or without obesity.
- Conditions
- Obesity, Aging, Aging Problems, Metabolic Syndrome
- Trial name
- Pro-Metage (NCT06511297)
- Testing
- comprehensive metabolic phenotyping
- Where
- 2 sites in Austria
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Thomas Scherer
Social Skills, Perfectionism
Effectiveness of the Universal Prevention Program Super Skills for Life in Schools
This study aims to evaluate the effectiveness of a 12-session cognitive-behavioral transdiagnostic protocol for Spanish children aged 8 to 12 within an educational context, Super Skills for Life.
- Conditions
- Social Skills, Perfectionism, Self Esteem, Positive Affect
- Trial name
- NCT06444581
- Testing
- Super Skills Schools
- Where
- Spain
- Volunteers
- 1,100 people
- Sponsor
- Universidad Miguel Hernandez de Elche
HIV, Frailty
Improving Physical Ability and Cellular Senescence Elimination in HIV
This clinical trial is a Phase II study designed to test the safety and effectiveness of a combination of dasatinib and quercetin (D+Q) in improving physical function for people with HIV who are frail or prefrail.
- Conditions
- HIV, Frailty, Prefrail, Aging Problems
- Trial name
- IPACE-HIV (NCT07144293)
- Testing
- Dasatinib, Quercetin
- Where
- 24 sites in United States
- Volunteers
- 82 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Age Problem, Fall
Fall Risk Assessment Using Hybrid Machine Learning and Deep Learning Approaches and a Novel Posturography
The purpose of this project is to combine a novel posturogrpahy based on HTC VIVE trackers and hybrid machine learning and deep learning algorithms to establish a set of simple, convenient and valid fall risk assessment tool.
- Trial name
- NCT05308563
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Inflammatory Disease, Aging Problems
Umbilical Cord Mesenchymal Stem Cell for Aging-related Low-grade Inflammation
The goal of this single-group, open-label, phase I/II clinical trial is to evaluate the safety and efficacy of the transplantation of umbilical cord mesenchymal stem cells in aging-related low-grade inflammation patients'…
- Conditions
- Inflammatory Disease, Aging Problems, Obese, Lipid Metabolism Disorders
- Trial name
- NCT06448052
- Testing
- umbilical cord mesenchymal stem cell
- Where
- Vietnam
- Volunteers
- 72 people
- Sponsor
- Nguyen Ton Ngoc Huynh
Feeding and Eating Disorders of Childhood, Appetite Disorders
Biolizin for Improving Functional Poor Appetite in Children Aged 6 to 36 Months (CTBE2502)
Functional poor appetite is common in young children and may be linked to suboptimal micronutrient intake and feeding behavior. This study evaluates whether a zinc-containing oral supplement (Biolizin syrup) can improve eating…
- Conditions
- Feeding and Eating Disorders of Childhood, Appetite Disorders, Functional Poor Appetite
- Trial name
- CTBE2502 (NCT07153549)
- Testing
- Biolizin, Standardized caregiver counseling on responsive feeding
- Where
- Vietnam
- Volunteers
- 110 people
- Sponsor
- Haiphong University of Medicine and Pharmacy
This Study Highlights Differences in Baropodometry Between Genders
Evaluation of the Effect of a Clinical Exercise Programme on Plantar Distribution and Correction of Postural Asymmetries
The aim of this study was to identify significant variables that contribute to the association between postural problems, plantar pressure distribution and levels of bodily pain in middle-aged and elderly adults.
- Trial name
- NCT06647355
- Testing
- Effectiveness of physical exercise in preventing pain and improving plantar pressure distribution
- Where
- Portugal
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Beira Interior
Anger Problems, Spiritual Well-being
Laughter Yoga's Impact on Children's Anger and Well-Being
This study aims to evaluate the effects of laughter yoga on anger levels and mental well-being in schoolchildren. Research indicates that laughter yoga has the potential to reduce stress and improve communication skills.
- Trial name
- NCT06827015
- Testing
- Laughter-Based Anger Reduction Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Mersin University
Age Problem
Assessing the Precision of Convolutional Neural Networks for Dental Age Estimation From Panoramic Radiographs
The aim of this study is to assess the accuracy of a convolutional neural network in dental age estimation from digital panoramic radiographs. The reference standard will be the chronological age of the patient.
- Trial name
- NCT05901857
- Testing
- convolutional neural network
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Chronic Disease, Chronic Condition
Feasibility and Potential Impact of an Individualized Exercise Program Via a Telerehabilitation Device in Chronic Patients: A Pilot Study
Exercise Rehabilitation (ER) is widely used and effective in the treatment of chronic diseases; however, patients do not adhere to ER programs.
- Conditions
- Chronic Disease, Chronic Condition, Stroke Sequelae, Age Problem
- Trial name
- NCT06558591
- Testing
- Telerehabilitation intervention
- Volunteers
- 50 people
- Sponsor
- Limoges University
Fall Injury, Age Problem
CatchU: A Quantitative Multisensory Falls-Assessment Study
The ability to successfully integrate information across sensory systems is a vital aspect of functioning in the real world. To date, only a few studies have investigated the clinical translational value of multisensory…
- Conditions
- Fall Injury, Age Problem, Well Aging, Sensory Disorders
- Trial name
- CatchU (NCT05544760)
- Testing
- CatchU Intervention
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Stroke, Aging Problems
Innovative Models in the Rehabilitation of the Elderly With Stroke Through Technological Innovation
The final goal of the present study is to propose a new approach and an innovative therapeutic plan in the post-stroke rehabilitation of elderly patients, focused on the use of robotic device, in order to obtain the beneficial…
- Conditions
- Stroke, Aging Problems, Innovative Rehabilitation Treatment Based on Robotics
- Trial name
- NCT04087083
- Testing
- Technological intervention arm, Control arm
- Where
- 2 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Age Problem
Impact of a Hospital Medication Expertise on Unplanned Hospitalizations at 3 Months of Nursing Homes Patients
The use of drugs in the elderly population remains a major public health problem worldwide. Technological advances and the development of new drugs have helped to extend life expectancy.
- Trial name
- TEM-EHPAD (NCT03640845)
- Testing
- tele-expertise
- Where
- France
- Volunteers
- 364 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Aging, Aging Problems
Brain Health Virtual Reality Study
The Interventions for Brain Health Virtual Reality Study is a NIH-funded clinical research trial at the University of California San Diego (UCSD) Health under the supervision of the study principal investigator Dr. Judy Pa.
- Conditions
- Aging, Aging Problems, Memory Loss, Memory Impairment
- Trial name
- NCT06124339
- Testing
- Physical Activity, Cognitive Activity (VR), Physical and Cognitive Activity
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Ostomy, Living in Roskilde County
Skin Problems in Ostomy Patients: An Epidemiological Study
Peristomal skin complications are thought to be common but the exact frequency and cause of these complications are unknown. We have sought to document the incidence of cutaneous peristomal problems and to find risk factors that…
- Conditions
- Ostomy, Living in Roskilde County, Persons More Than 18 Years of Age, Willingness to Participate
- Trial name
- NCT00391508
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Age Problem
Efficacy of the Otago Exercise Program Delivered as Group Training Versus Individually Tailored Training
A non-inferiority controlled clinical trial using randomization for allocation at the level of general practice in 21 centers (in 8 Spanish regions), to compare a group Otago exercise program (OEP) [delivered by specifically…
- Trial name
- NCT03320668
- Testing
- Otago Exercise Program (OEP)
- Where
- 9 sites in Spain
- Volunteers
- 878 people, healthy volunteers welcome
- Sponsor
- Instituto de Salud Carlos III
Metabolic Diseases, Aging Problems
Brain Substrate Switch to Ketones and Lactate
The brain is constantly active and energetically expensive, making up a quarter of the body's energy budget despite occupying only 2% of its mass.
- Trial name
- BSS (NCT06000605)
- Testing
- Fed, Fasted
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Aging Problems
Vascular Aging and Microcirculation: Physiological Aspects of Vascular Aging in the Elderly Population (VAMP-Aging)
Rising life expectancy worldwide challenges public health due to increased cardiovascular disease linked to vascular aging, where microvascular dysfunction serves as an early indicator of system-wide inflammation, or…
- Trial name
- VAMP-Aging (NCT07563725)
- Testing
- Laser Speckle Contrast Imaging, Handgrip Dynamometry (Muscle Strength), Sit-to-Stand Test (5-Times Sit-to-Stand - 5STS)
- Where
- Brazil
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Age Problem, Old Age; Debility
Swedish Palliative Care Guide (S-PCG) at Nursing Homes
Palliative care aims to improve the quality of life for patients and families who are affected life-threatening, incurable disease. The care should be person-centred, but it is not entirely clear how this is best achieved.
- Conditions
- Age Problem, Old Age; Debility, Dementia
- Trial name
- NCT06431659
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Region Skane
Aging Disorder, Aging Problems
Effects of Footwear Suitability on Functional Performance and Balance in Elderly
Proper footwear serves to protect the foot against external factors. Balance and functional performance are affected by the level of footwear suitability.
- Conditions
- Aging Disorder, Aging Problems, Aging
- Trial name
- NCT04151654
- Testing
- Footwear Assessment Score
- Volunteers
- 154 people
- Sponsor
- Tuba Maden