Clinical trials: Age-Related Maculopathy
Age Related Macular Degeneration
Life Style and Food Habits Questionnaire in the Portuguese Population Aged 55 or More
The study population will be selected from the "Epidemiological study on the prevalence of Age related Macular Degeneration in Portugal" (Protocol N.
- Trial name
- NCT01715870
- Testing
- Life style and food habits questionnaire
- Where
- Portugal
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Association for Innovation and Biomedical Research on Light and Image
Age Related Cognitive Decline, Age Related Macular Degeneration
Walnuts and Healthy Aging
This will be a systematic investigation of the role of walnuts in preventing or slowing age related cognitive decline and age related macular degeneration.
- Trial name
- WAHA (NCT01634841)
- Testing
- Walnuts, habitual diet
- Where
- 2 sites in United States, Spain
- Volunteers
- 708 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Age Related Macular Degeneration
Effect of Oral Curcumin Supplementation in Dry Age-related Macular Degeneration (AMD) Patients
Nutrition plays an important role in preventing progression of dry age related macular degeneration (AMD), a disease of aging that leads to drusen deposits in the macula causing significant decrease in vision.
- Trial name
- NCT04590196
- Testing
- Longvida curcumin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Age-Related Macular Degeneration
The Role of Complement Factor H Polymorphism in the Regulation of Choroidal Vascular Tone in Young Healthy Subjects
Age related macular degeneration (AMD) is a multifactorial disease with a strong genetic component. Given that it is known that impaired regulation of choroidal vascular tone is present in patients with AMD, the current study…
- Trial name
- NCT02102880
- Testing
- the polymerase chain reaction (PCR)
- Where
- Austria
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Neovascular Age-Related Macular Degeneration
Evaluation of Pain and Inflammation After Injection of Lucentis vs Eylea for Treatment of Wet Macular Degeneration
This study is designed to compare the post injection inflammation and pain seen after intravitreal injections of Ranibizumab vs Aflibercept.
- Trial name
- NCT01926977
- Testing
- Ranibizumab 0.5mg, Aflibercept 2.0mg
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Arshad Khanani
Age Related Macular Degeneration
Mobile Clinic - a Cross-sectional Epidemiological Survey
The aim of the study is to find out prevalence of aged-related macular degeneration (AMD) in Slovak Republic. The outcome of the project will be epidemiology survey, prevalence of wet form of AMD in relation to demographic data…
- Trial name
- NCT02055612
- Where
- Slovakia
- Volunteers
- 3,278 people, healthy volunteers welcome
- Sponsor
- Novartis Slovakia, s.r.o.
Wet Age Related Macular Degeneration
Clinical Study for the Evaluation of Safety and Tolerability of SCAI-005 Eye Drops
To assess the single-dose and multiple-dose pharmacokinetics (PK), safety and tolerability of SCAI-005 eyedrops(axitinib) in healthy volunteers
- Trial name
- NCT06969001
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- SCAI Therapeutics
Neovascular (Wet) Age-related Macular Degeneration (AMD)
OCT Angiography in Wet AMD
The primary goals of this study are to use optical coherence tomography (OCT) angiography (blood vessel mapping) to: 1. diagnose the presence of new blood vessels in wet age-related macular degeneration (AMD) 2.
- Trial name
- NCT02253030
- Testing
- Optical Coherence Tomography
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Neovascular Age Related Macular Degeneration
NVAMD Satellite Study
Intravitreal delivery of anti-vascular endothelial growth factor (VEGF) drugs has revolutionized the management of neovascular age-related macular degeneration (NVAMD).
- Trial name
- NCT02251366
- Testing
- Physician-guided diagnostic
- Where
- 5 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Age-related Macular Degeneration
Effects of Sildenafil on Choroidal Thickness in AMD
Choroidal thinning has been hypothesized to partake in the pathogenesis of age-related macular degeneration (AMD), but it is not known if increasing choroidal thickness may potentially alter the disease course.
- Trial name
- NCT01830790
- Testing
- Sildenafil citrate
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Duke University
Visual Impairment, Age-Related Macular Degeneration (AMD)
Prevalence and Determinants of Shoulder Girdle Musculoskeletal Complaints in Geriatric Patients With Diminished Vision
This case-control study aims to investigate the prevalence and determinants of shoulder girdle musculoskeletal complaints (pain, spasm, stiffness, range of motion impairments) in geriatric patients (aged 60+) with diminished…
- Conditions
- Visual Impairment, Age-Related Macular Degeneration (AMD), Musculoskeletal Pain, Shoulder Pain
- Trial name
- NCT07206654
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Cataract, Macular Degeneration Advanced
Cataract Surgery on Advanced Age Related Macular Degeneration Patients
The degree at which cataract surgery improves visual function in patients with advanced age-related macular degeneration (Advanced AMD) has been an on-going topic of discussion.
- Trial name
- NCT04045704
- Testing
- Cataract Surgery
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Neovascular Age-related Macular Degeneration
Functional and Structural Outcomes in Neovascular Age-related Macular Degeneration
Several studies during the last years reported the involvement of anti-retinal autoantibodies in ocular disorders, such as AMD. These studies support the growing evidence of an immunological involvement in the pathogenesis of…
- Trial name
- CAPTAIN (NCT02843490)
- Testing
- Ranibizumab
- Where
- Germany
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Age-Related (Dry) Macular Degeneration
Real-World Evaluation of AI Enabled Multi-Spectral Imaging (MSI) for AMD Biomarker Detection
The goal of this observational clinical study is to learn if DeepMSI AI detects age-related macular degeneration (AMD) biomarkers with sensitivity and specificity equivalent to experienced clinicians in adults over 40 years old.
- Trial name
- NCT07446582
- Testing
- Retina imaging device (MSI-120) and AI (DeepMSI AI)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- AI-Spectral
Age-related Macular Degeneration, Choroidal Neovascular Age-related Macular Degeneration
Association of Macular Pigment Optical Density (MPOD) and Genetic Variants in Complement Factor H in Subjects With Choroidal Neovascular (CNV)
Subjects with wet AMD, dry AMD, and age-matched controls will undergo routine occular measurements, will provide a blood and cheek cell sample, and will have macular pigment optical density (MPOD) measured to determine if there…
- Trial name
- NCT01682382
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sequenom, Inc.
Age-Related Macular Degeneration
Lucentis Utilizing Visudyne (LUV Trial) Combination Therapy in the Treatment of Age-Related Macular Degeneration
The PDT/Lucentis trial will be a Phase IV comparative trial comparing the use of combination therapy with ITV ranibizumab and verteporfin PDT to ITV ranibizumab alone in patients with exudative AMD.
- Trial name
- NCT00423189
- Testing
- Ranibizumab (Lucentis), 0.5mg ranibizumab
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- David M. Brown, M.D.
Age-Related Macular Degeneration, Diabetic Retinopathy
National Eye Institute Biorepository for Retinal Diseases
Background: To understand diseases of the retina and the eye, information is needed about people with and without such diseases. Researchers want to study these people and follow them over time.
- Conditions
- Age-Related Macular Degeneration, Diabetic Retinopathy, Von Hippel-Lindau Syndrome, Retinal Disease
- Trial name
- NCT01496625
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Age Related Macular Degeneration
Intravitreal Bevacizumab for Choridal Neovascularization Secondary to Age-Related Macular Degeneration
To report the short term anatomic and visual acuity response after intravitreal injection of bevacizumab (Avastin, Roche, Rio de Janeiro, Brazil) in patients with choroidal neovascularization secondary to age-related macular…
- Trial name
- NCT00556348
- Testing
- bevacizumab
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Instituto de Olhos de Goiania
Aged Macular Degeneration
Omega-3-fatty Acids on Age-related Macular
Aim: To demonstrate the short-term multi focal electroretinogram (mfERG) effect of oral omega-3-fatty acids in the triglyceride form on dry age-related macular degeneration (AMD).
- Trial name
- Omega 3 (NCT01258335)
- Testing
- Omega 3, Olive Oil
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mid Atlantic Retina
Neovascular Age-related Macular Degeneration
Development of an Optimal Algorithm for the Management of Patients With Retinal Pigment Epithelium Detachment in Neovascular Age-related Macular Degeneration Using Artificial Intelligence
The study involves the development of an algorithm for predicting anatomical and functional results of therapy with angiogenesis inhibitors in patients with retinal pigment epithelium detachments in neovascular age-related…
- Trial name
- NCT05208931
- Testing
- Anti-vascular endothelial growth factor therapy
- Where
- Russia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution