Clinical trials: Aggressive Behaviour
Tooth Loss
Long-term Results After Systematic Periodontal Therapy
Patients who had had systematic periodontal treatment (antiinfective treatment with subgingival debridement under local anaesthesia and if required periodontal surgery) at the Dept.
- Trial name
- SYSPERIO10 (NCT03048045)
- Testing
- Supportive Periodontal Treatment (SPT)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Goethe University
Schizophrenia, Psychosis
Quetiapine Extended Release (XR) for the Management of Psychotic Aggression or Agitation in Adult Acute Psychiatry
This study is a multi-site study examining the use of Quetiapine XR for psychotic aggression in an acute psychiatric setting. The study aims to demonstrate that management with Quetiapine XR significantly reduces aggressive…
- Trial name
- NCT00986167
- Testing
- Quetiapine XR
- Where
- 2 sites in Australia
- Volunteers
- 72 people
- Sponsor
- Bayside Health
Ventilator Induced Lung Injury, Cardiac Disease
Intensive Alveolar Recruitment Protocol After Cardiac Surgery
The purpose of this study was to evaluate prospectively the impact of two protective mechanical ventilation strategies, both using low tidal volume ventilation (6 mL/kg/ibw) after cardiac surgery.
- Conditions
- Ventilator Induced Lung Injury, Cardiac Disease, Acute Lung Injury
- Trial name
- NCT01502332
- Testing
- Intensive Alveolar Recruitment, Moderate Alveolar Recruitment
- Where
- Brazil
- Volunteers
- 320 people
- Sponsor
- University of Sao Paulo
Lymphoma
Chemotherapy and Radiation Therapy Plus Bone Marrow Transplantation in Treating Patients With Aggressive Non-Hodgkin's Lymphoma
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells.
- Trial name
- NCT00003815
- Testing
- bleomycin sulfate, carmustine, cyclophosphamide
- Where
- United Kingdom
- Sponsor
- Scotland and Newcastle Lymphoma Group
Psychiatric Hospitalization
Diet and Aggression: Reducing Aggression Among Chronic Psychiatric Inpatients Through Dietary Supplementation
The overall goal of this study is to investigate whether the daily administration of multivitamins, minerals and n-3 fatty acids will reduce aggression in long-term psychiatric inpatients and will thereby reduce costs of care.
- Trial name
- NCT02498106
- Testing
- Orthica Soft Multi Mini and Orthica Fish EPA Mini
- Where
- 6 sites in Netherlands
- Volunteers
- 176 people
- Sponsor
- Leiden University Medical Center
Desmoid Tumor
Imatinib Mesylate in Treating Patients With Recurrent or Refractory Fibromatosis
RATIONALE: Imatinib mesylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase I/II trial is studying the side effects of imatinib mesylate and to see how well it works…
- Trial name
- NCT00287846
- Testing
- imatinib mesylate
- Where
- 23 sites in France
- Volunteers
- 40 people
- Sponsor
- UNICANCER
Schiphrenia
Mindfulness-Integrated Psychoeducation for Patients With Schizophrenia
This study aims to evaluate the effectiveness of a mindfulness-integrated psychoeducational nursing intervention in enhancing insight, improving medication adherence, and reducing aggressive behaviors among patients with…
- Trial name
- MIPNI-Schizo (NCT07917520)
- Testing
- Mindfulness-Integrated Psychoeducational Nursing Intervention
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Weaning Failure
Speeding the Weaning up: Aggressive Screening Criteria and Higher Minimal Ventilatory Settings.
Hypothesis: 1. In patients with less than 4 high risk factors for reintubation excluding body mass index >30 and hypercapnia during the spontaneous breathing trial (SBT) (low and intermediate risk for extubation failure), who…
- Trial name
- SPEED-UP (NCT04758546)
- Testing
- Screening criteria for weaning and minimal ventilatory settings for spontaneous breathing trial
- Where
- Spain
- Volunteers
- 940 people
- Sponsor
- Gonzalo Hernandez Martinez
Lymphoma, Non-Hodgkin
Evaluation of Bay 59-8862 in Patients With Aggressive, Refractory Non-Hodgkin's Lymphoma
Almost two-thirds of lymphoma cases are Non-Hodgkin's Lymphomas (NHL). NHL is a malignant process that affects lymphoid cells found both in the lymph nodes and extranodally.
- Trial name
- NCT00044551
- Testing
- Taxane (Cytotoxic, BAY59-8862)
- Where
- 23 sites in United States, Canada and 4 more
- Volunteers
- 29 people
- Sponsor
- Bayer
Aggressive B-Cell Non-Hodgkin Lymphoma, Ann Arbor Stage III Grade 2 Follicular Lymphoma
ALX148, Rituximab and Lenalidomide for the Treatment of Indolent and Aggressive B-cell Non-Hodgkin Lymphoma
This phase I/II trial finds out the best dose, possible benefits and/or side effects of ALX148 in combination with rituximab and lenalidomide in treating patients with indolent and aggressive B-cell non-Hodgkin lymphoma.
- Conditions
- Aggressive B-Cell Non-Hodgkin Lymphoma, Ann Arbor Stage III Grade 2 Follicular Lymphoma, Ann Arbor Stage III Grade 3 Follicular Lymphoma, Ann Arbor Stage III Marginal Zone Lymphoma
- Trial name
- NCT05025800
- Testing
- CD47 Antagonist ALX148, Lenalidomide, Rituximab
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- M.D. Anderson Cancer Center
Pancreatic Adenocarcinoma, Gastric Adenocarcinoma
Resilience and Exercise in Advanced Cancer Treatment
This is a pilot study to evaluate the feasibility of, adherence to, and early efficacy of Band Together, a strength-training and walking program (intervention arm) vs.
- Conditions
- Pancreatic Adenocarcinoma, Gastric Adenocarcinoma, Adenocarcinoma of the Gastroesophageal Junction
- Trial name
- REACT (NCT02680990)
- Testing
- Band Together, Exercise Education
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Milton S. Hershey Medical Center
Disruptive Behavior, Aggression
Cognitive-Behavioral Therapy for Disruptive Behavior in Children and Adolescents
This is a randomized controlled study of cognitive-behavioral therapy (CBT) for disruptive behavior such as irritability, anger and aggression in children and adolescents.
- Conditions
- Disruptive Behavior, Aggression, Anger, Irritability
- Trial name
- RDoC-CBT (NCT01965184)
- Testing
- Cognitive-Behavioral Therapy for Anger and Aggression, Supportive Psychotherapy (SPT)
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Yale University
Generalized Aggressive Periodontitis
Gene Expression Profiles in Generalized Aggressive Periodontitis: A Gene Network-based Microarray Analysis
In this study, the investigators evaluated molecular biomarkers which play a role in the development of generalized aggressive periodontitis (GAgP) using gingival tissue samples through omics-based whole-genome transcriptomic…
- Trial name
- NCT02327533
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
COMBO Condition, STIGMA Condition
Effects of Internet-based Storytelling Programs in Reducing Mental Illness Stigma With Mediation by Interactivity and Stigma Content
Mental illness stigma has been a concerning issue globally due to its adverse effects on the recovery of people with mental illness and may delay help-seeking for mental health out of the concern of being stigmatized.
- Conditions
- COMBO Condition, STIGMA Condition, INTERACT Condition, CONTROL Condition
- Trial name
- NCT05333848
- Testing
- Internet-based storytelling programs with interactivity and stigma content, Internet-based storytelling programs with stigma content only, Internet-based storytelling programs with interactivity only
- Where
- Hong Kong
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Aggressive Periodontitis
Gingival Crevicular Fluid Levels Of Monocyte Chemoattractant Protein-1
The aim of this study is to estimate GCF MCP-1 levels of healthy and Aggressive periodontitis (AgP) subjects and to compare MCP-1 levels between Localized AgP (LAgP) and Generalized AgP (GAgP) to establish its predictive…
- Trial name
- MCP-1 (NCT02927704)
- Testing
- Gingival crevicular fluid (GCF) sample
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Bullying
The Effect of School-Based Bullying Prevention Program on Bullying Victimization, Tendencies and Future Expectations of Adolescents
The aim of this study is to determine the effect of a school-based bullying prevention program on adolescents' bullying victimization, tendencies and future expectations.
- Trial name
- NCT06663215
- Testing
- School Based Bullying Prevention Program
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Harran University
Periodontitis, Adult, Periodontitis, Aggressive
Efficacy of Sub-gingival Air-polishing With Erythritol in the Treatment of Periodontitis
The first step in the management of periodontal disease involves the non-surgical removal of the soft and hard bacterial deposits at all supra- and sub-gingival sites, especially into deep pockets, which can be carried on with…
- Trial name
- GBT2017 (NCT04264624)
- Testing
- Perioflow and Erythritol powder and ultrasonic debridement, Airflow and Erythritol powder and ultrasonic debridement
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Alzheimer's Disease
Treatment for Aggression and Agitation in Patients With Alzheimer's Disease
The purpose of this study is to determine whether this drug can help symptoms of aggression and agitation in participants with Alzheimer's disease.
- Trial name
- NCT00843518
- Testing
- LY451395
- Where
- 17 sites in United States
- Volunteers
- 132 people
- Sponsor
- Eli Lilly and Company
Alzheimer Disease, Psychotic Disorders
Antipsychotic Discontinuation in Alzheimer's Disease
In patients with Alzheimer's disease (AD) who respond to antipsychotic treatment of psychosis and/or agitation/aggression, the relapse risk after discontinuation is not established.
- Conditions
- Alzheimer Disease, Psychotic Disorders, Agitation, Aggression
- Trial name
- ADAD (NCT00417482)
- Testing
- risperidone
- Where
- 7 sites in United States
- Volunteers
- 180 people
- Sponsor
- New York State Psychiatric Institute
Relapsed/Refractory Aggressive B-Cell Malignancies
A Clinical Study of ONCT-808 in Subjects With Relapsed or Refractory B-Cell Malignancies
This is a Phase 1/2 study to investigate the safety and efficacy of the CAR-T therapy, ONCT-808, in patients with relapsed/refractory (R/R) aggressive B cell malignancies.
- Trial name
- NCT05588440
- Testing
- ONCT-808, Bridging Therapy
- Where
- 4 sites in United States
- Volunteers
- 9 people
- Sponsor
- Oncternal Therapeutics, Inc