Clinical trials: Aging, Healthy
Healthy Ageing
Efficacy of a Toe Flexion Training Protocol on Older Adults' Mobility
This randomized controlled trial aims to explore the effect of a toe flexion resistance training protocol on toe flexion strength and morphology, as well as in older adults (65-85 completed years) mobility related construct.
- Trial name
- PRP-Pied-AUT (NCT05703945)
- Testing
- Progressive training program, Control group
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Dysphagia, Healthy Aging
Swallowing Impairments in ICU Survivors and Community-Dwelling Adults
Post-intensive care syndrome (PICS), which consists of physical, cognitive, and psychosocial problems, is a pervasive complication for older intensive care unit (ICU) survivors and contributes to detrimental health outcomes and…
- Conditions
- Dysphagia, Healthy Aging, Post Intensive Care Syndrome, Caregiver Burden
- Trial name
- NCT07005037
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Hearing Impaired
Brain and Cognitive Changes After Reasoning or Physical Training in Cognitively Normal Seniors
Seniors 65 years of age and older represent one of the fastest growing segments of society with the population doubling within the next 25 years with dramatic rates of mental decline, costing society billions of dollars each…
- Trial name
- NCT00977418
- Testing
- SMART- Strategic Memory and Reasoning Training, Physical Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Healthy Ageing
Vasopressin in the Elderly: Physiological Changes in Neuroendocrine Function and Urinary Secretion in Healthy Aging
Elderly people are at a high risk for disturbances in water homeostasis, with both hypo- and hypernatremia being more common with increasing age.
- Trial name
- VENUS (NCT06930300)
- Testing
- Hypertonic 3% saline, Water
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Cognitive Decline, Cognitive Impairment
Effects of Cognitive Intervention on Cognition, Mobility and Brain Electrocortical Activity
Within this project the investigators tested the effectiveness of 2-month of computerized cognitive training (CCT) on CogniFit online platform on 77 older adults, which were randomly divided into intervention and control group.
- Conditions
- Cognitive Decline, Cognitive Impairment, Aging, Motor Coordination or Function
- Trial name
- GIBKOP (NCT03860441)
- Testing
- Computerized cognitive training
- Where
- Slovenia
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Science and Research Centre Koper
Healthy
REMINDer - A Digital Environmental Enrichment Intervention
The primary goal of this pilot study is to assess the feasibility and effectiveness for improving overall mental and physical well-being of a multimodal intervention program in older adults carried out in a digital telehealth…
- Trial name
- REMINDer (NCT06530277)
- Testing
- REMINDer (A digital environmental enrichment intervention)
- Where
- Germany
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- German Center for Neurodegenerative Diseases (DZNE)
Aging
Non-invasive Nerve Stimulation and Cognitive Training to Improve Cognitive Performance in Healthy Older Adults
Decline in brain health and associated loss of cognitive function in healthy aging decreases quality of life.We need better tools to both enhance brain health and improve cognitive performance in healthy brain aging so that it…
- Trial name
- NCT04276805
- Testing
- Transcutaneous vagal nerve stimulation (tVNS), Cognitive training
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Florida
Healthy Aging, Lifestyle-related Condition
Nicotinamide Riboside Supplementation and Exercise Training to Promote Healthy Longevity
The prevalence of age-related chronic diseases (like obesity, type 2 diabetes and cardiovascular diseases) is mounting worldwide, reaching pandemic proportions.
- Conditions
- Healthy Aging, Lifestyle-related Condition, Metabolic Diseases
- Trial name
- RESTORENAD (NCT06425042)
- Testing
- Nicotinamide Riboside (NR)
- Where
- Chile
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Finis Terrae University
Healthy Young Adults, Prefrail Elderly
GOS and Microbial Fermentation in Aging
The population is aging worldwide, concomitant frailty is increased in older age groups. Frailty has a strong impact on outcomes of multi-morbidity and daily living, thereby negatively influencing quality of life and health care…
- Trial name
- NCT03077529
- Testing
- Galacto-oligosacchride, Maltodextrin
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy Aging
Effects of Brisk Walk With Low Intensity in Elderly
The goal of this clinical trial is to compare the effects of brisk walk with low intensity aerobic exercises on flexibility balance muscle endurance and life satisfaction in healthy elderly population.
- Trial name
- NCT05751083
- Testing
- brisk walk+ low intensity aerobic exercises, Brisk walk
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Skin Aging, Dry Skin
Effects of Probiotics on Skin Health in Healthy Women
The effect of probiotics on skin health in healthy women with dry to very dry facial skin.
- Trial name
- NCT07887841
- Testing
- Probiotics
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Probi AB
Exercise, Self Efficacy
Social Media Chatbot on Physical Activity Education for Older Adults
In this study, a social media chatbot was used to provide a continuous and real-time multimedia health education program on physical activity for the older adults, as well as supportive messages and feedbacks, to improve physical…
- Conditions
- Exercise, Self Efficacy, Behavioral Regulation, Healthy Aging
- Trial name
- NCT06423040
- Testing
- Social Media Chatbot on Physical Activity Education
- Where
- Taiwan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Cognitive Change, Mood
Turmeric for Memory Impairment and Cognition
The objective of the study is to test the capacity of acute and chronic supplementations of Turmipure GOLD® to improve cognitive performance in healthy aging
- Conditions
- Cognitive Change, Mood, Stress
- Trial name
- TURMEMIC (NCT04860050)
- Testing
- Turmipure Gold®
- Where
- Ireland
- Volunteers
- 568 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Quality of Life, Aging Well
Care of the Ageing Veteran Population: Developing an Evidence Base for the Royal Hospital Chelsea Model of Care
Royal Hospital Chelsea (RHC) has provided a sheltered housing environment alongside integrated health and social care and comradeship for British Army veterans since 1692, following a decree by King Charles II to aid the "relief…
- Trial name
- NCT04828018
- Testing
- Coffee Morning, Recruitment Leaflets, Consent Form completion
- Where
- United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Healthy Aging
Online Grammatical Reasoning Training for Older Adults
The START study will investigate the impact of playing a Grammatical Reasoning brain training task on overall brain function (cognition) and day-to-day function in people over 50. .
- Trial name
- START (NCT03661190)
- Testing
- Grammatical Reasoning, Card Pairs
- Where
- United Kingdom
- Volunteers
- 6,544 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Alzheimer Disease, Healthy Aging
Amyloid Imaging With 11C-PiB in Healthy Aging and Mild Cognitive Impairment
The purpose of this study is to measure the amount of amyloid in the brain. Amyloid is a protein found in the brain of patients with Alzheimer's disease and can be detected using a Positron Emission Tomography (PET) scan.
- Trial name
- NCT04505735
- Testing
- 11C-PiB
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Aging
Efficiency of New Technologies in the Aging Process
This study tries to analyze the effectiveness of the application of the new technology in the maintenance of an active time. To do this, the investigators performed a laboratory test where they evaluated the physical and…
- Trial name
- NCT04615897
- Testing
- new tecnology intervention
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Seville
Brain Health, Longevity
L-serine and Strength Training in the Elderly
This study investigates whether taking the amino acid L-serine, either alone or in combination with targeted strength training, can have a positive effect on mental performance, brain function, and physical fitness in older…
- Conditions
- Brain Health, Longevity, Cognitive Performance, Strength Training Effects
- Trial name
- AAAging (NCT07466290)
- Testing
- Strength training, L-serine supplementation, Control (cornstarch)
- Where
- Austria
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Healthy Participants
Tolerance of an Immersive Virtual Reality Task Evaluating the Spatial Memory of Elderly Subjects
Spatial navigation is a high-level cognitive function allowing animals and humans to orient and move in space by constructing a mental representation of the environment.
- Trial name
- REVIAGE (NCT05996250)
- Testing
- Immersive virtual reality task
- Where
- France
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Parkinson's Disease (PD), Healthy Aging
Exoskeleton-Assisted Mobility in Aging and in Parkinson's Disease
This study will evaluate whether a wearable robotic exoskeleton can improve mobility, balance, and walking in healthy older adults and in individuals living with Parkinson's disease, populations at high risk of falls and mobility…
- Trial name
- NCT07567482
- Testing
- Exoskeleton
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Centre intégré de santé et de services sociaux de l'Outaouais