Clinical trials: Aging
Heart Failure, Cardiomyopathies
Multimodal Physiologic State Intelligence Study
The OMNIPHYS study will investigate whether multimodal ultrasound and other routinely collected clinical and physiologic data can be combined with artificial intelligence to characterize changes in a person's physiologic state…
- Conditions
- Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute
- Trial name
- OMNIPHYS (NCT07814118)
- Testing
- OMNIPHYS Multimodal Ultrasound Imaging System
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Aging, Mortality
Longevity Metrics AI/ML Development Study
This study builds AI models that score diagnostic screening tests, and that predict screening results, clinical judgment, and life expectancy.
- Conditions
- Aging, Mortality, Cardiovascular Disease Prevention, Metabolic Syndrome
- Trial name
- NCT07808619
- Testing
- AIML scored health screening battery
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Aging, Aging Well
100-Year Human Aging Study
The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed clinical sites, mobile clinical sites, and an online participation pathway (current and future) to undergo…
- Conditions
- Aging, Aging Well, All-Cause Mortality, Mortality
- Trial name
- NCT07563777
- Testing
- Comprehensive Multi-System Clinical Screening
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Aging, Mortality
Human Observatory Study
The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level.
- Conditions
- Aging, Mortality, All-cause Mortality, Life Expectancy
- Trial name
- HOS (NCT07646782)
- Testing
- Multi-Domain Ecological and Clinical Data Linkage
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Health Services Accessibility, Rural Health
Health Ahead Comparative Effectiveness Study
The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening…
- Conditions
- Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services
- Trial name
- HACE (NCT07669168)
- Testing
- AI-Assisted Screening Interpretation (AI Reads), Human-Only Screening Interpretation
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- William Brandenburg, MD
Aging, Aesthetic
Clinical Performance and Safety of STYLAGE® HydroMax
FHAME is a post-market clinical investigation designed to strengthen the clinical evidence supporting the effectiveness of STYLAGE® HydroMax in the treatment of superficial wrinkles, primarily on the cheeks.
- Trial name
- FHAME (NCT07153237)
- Testing
- STYLAGE® HydroMax
- Where
- 2 sites in France
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Aging, Balance Deficits
Examining the Effects of Theta Burst TMS on Brain Connectivity and Balance Ability in Older Adults With Balance Problems
The goal of this study is to learn if manipulating the brain using magnets works to treat balance impairment, a major cause of falls, in older adults with balance problems.
- Trial name
- NCT06779188
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Weinberg Medical Physics LLC
Aging, Dry Skin
Efficacy and Safety of a Topical Botanical Extract Formulation for Skin Aging
This is a single-center, double-blinded, placebo-controlled, split-face, prospective clinical study to evaluate the anti-ageing efficacy and safety of a topical cosmetic formulation containing a botanical extract.
- Trial name
- NCT07780799
- Testing
- Cosmetic Topical Formulation 1, Cosmetic Base of Topical Formulation 1, Cosmetic Topical Formulation 2
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Skin Aging on Face, Skin Care Dermocosmetics
Efficacy of Topical Niacinamide Riboside on the Signs of Facial Skin Aging
Niacinamide riboside (topical NR, also known as nicotinamide riboside) is an endogenous compound and a precursor (building block) to the essential cellular co-enzyme, nicotinamide adenine dinucleotide (NAD+).
- Conditions
- Skin Aging on Face, Skin Care Dermocosmetics, Skin Care, Fine Lines and Wrinkles
- Trial name
- NR-RADIANCE (NCT07774000)
- Testing
- Topical niacinamide riboside
- Where
- South Africa
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- ChromaDex, Inc.
Facial Skin Aging, Facial Volume Loss
Comparing Facial Aging Between Identical Twins With 3D Imaging
Identical twins share the same genes, which makes them a powerful way to study how lifestyle and environment - rather than genetics - affect how faces age.
- Conditions
- Facial Skin Aging, Facial Volume Loss, Wrinkle Appearance
- Trial name
- NCT07760532
- Testing
- GLP-1 Receptor Agonists
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ponsky Facial Aesthetics And Plastic Surgery, Llc
Skin Aging, Hair Care
A Pilot Study to Evaluate the Expanded Reach of Decentralized Digital Skin Health Clinical Studies
This is a randomized, decentralized, non-interventional clinical study. The primary objective of this study is to develop execution and efficiency metrics from completion of this study to inform on the potential design for future…
- Conditions
- Skin Aging, Hair Care, Skin Microbiome
- Trial name
- NCT07193290
- Testing
- Lifestyle Questionnaire, Self-portrait image (Face and Hair), Skin microbiome collection
- Where
- United States
- Volunteers
- 1,027 people, healthy volunteers welcome
- Sponsor
- Kenvue Brands LLC
Skin Aging, Skin Hydration
A Clinical Trial to Evaluate the Effects of Naila's Collagen Marine Plus Food Supplement on Skin Hydration, Elasticity, Fine Lines and Wrinkles, and Hair and Nail Health
This is a single-group, open-label, virtual (decentralized) clinical trial evaluating the effects of Naila's Collagen Marine Plus Food Supplement on skin hydration, elasticity, firmness, fine lines and wrinkles, and hair and nail…
- Conditions
- Skin Aging, Skin Hydration, Skin Elasticity, Fine Lines and Wrinkles
- Trial name
- NCT07746076
- Testing
- Naila's Collagen Marine Plus Food Supplement
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gulf Bird
Aging
E-training of Inmate Peer Caregivers for Enhancing Geriatric and End-of-life Care in Prisons
The demographics of the U.S. prison population are shifting at a dramatic rate requiring new approaches to prison healthcare. Current estimates suggest that there are 2.3 million incarcerated persons in the U.S.
- Trial name
- NCT05017129
- Testing
- Just Care
- Where
- 2 sites in United States
- Volunteers
- 83 people
- Sponsor
- Klein Buendel, Inc.
Facial Aging
Evaluating Facial Skin Quality Changes Post-Lipofilling
The goal of this prospective observational study is to evaluate changes in facial skin quality and identify predictive biological markers in donor adipose tissue in healthy women undergoing autologous facial fat transfer.
- Trial name
- NCT07737639
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Healthy Aging
Improving Neurological Health in Aging Via Neuroplasticity-based Computerized Exercise
This study is a validation study to evaluate efficacy of a neuroplasticity-based, computerized cognitive training program INHANCE (Improving Neurological Health in Aging via Neuroplasticity-based Computerized Exercise) to improve…
- Trial name
- INHANCE (NCT04149457)
- Testing
- Computerized Plasticity-Based Adaptive Cognitive Training, Commercially available computerized training
- Where
- Canada
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Posit Science Corporation
Aging, Wrinkle Appearance
Anti-aging Efficacy Study on One Cosmetic Product Containing Mitopure
The aim of this study is to investigate the impact of a topical product on skin health and aging
- Trial name
- HCP-S1 (NCT07517887)
- Testing
- Skin care product
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Facial Aging, Rejuvenation
Secretome Treatment for Facial Rejuvenation
Secretome treatment for facial rejuvenation
- Conditions
- Facial Aging, Rejuvenation, Stem Cell, Stem Cell Banking
- Trial name
- NCT07227883
- Testing
- Autologous Hair Follicle-Derived Secretome, Control Saline
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Acorn Biolabs Inc.
Systemic Inflammation (hsCRP), Healthy Aging
Evaluation of AppleX™ Apple Extract on Anti-Inflammatory and Healthy Aging Effects
The goal of this clinical trial is to learn if AppleX™ Apple Extract can help lower systemic inflammation in adults aged 45-70 with signs of low-grade inflammation.
- Conditions
- Systemic Inflammation (hsCRP), Healthy Aging, Vitality, Healthy Adult Participants
- Trial name
- NCT07678346
- Testing
- Apple Extract
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nutraland USA, Inc.
Autophagy, Healthy Aging
Effects of Miricell Supplementation on Biomarkers of Healthy Aging and Autophagy
The goal of this clinical trial is to learn if a dietary supplement called Miricell works to improve cellular health and signs of healthy aging in adults. It will also learn about the safety of Miricell.
- Trial name
- NCT07675200
- Testing
- Spermidine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nutraland USA, Inc.
Skin Aging, Wrinkles in Decolletage
PIEZO-101 First-in-Human Safety and Proof-of-Concept Study
The aim of this first-in-human clinical study is to explore the safety, tolerability, pharmacodynamics, and exploratory efficacy of PIEZO-101, an investigational plasmid DNA biostimulator that aims to restore expression of key…
- Conditions
- Skin Aging, Wrinkles in Decolletage, Wrinkles in Left Knee, Left Knee Skin Laxity
- Trial name
- NCT07671027
- Testing
- PIEZO-101, Piezopen, Sterile Saline (0.9% NaCl)
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Piezo Therapeutics, Inc.