Clinical trials: Aging
Type 2 Diabetes Mellitus With Hypoglycemia, Aging
Prepare for Your Diabetes Care
As adults with type 2 diabetes age, they are increasingly vulnerable to treatment-related hypoglycemia and its related complications (including hospitalization and death).
- Conditions
- Type 2 Diabetes Mellitus With Hypoglycemia, Aging, Patient Activation
- Trial name
- NCT05263310
- Testing
- Prepare for Your Diabetes Care, Usual Care
- Where
- United States
- Volunteers
- 672 people
- Sponsor
- Kaiser Permanente
Healthy Aging
Effect of Vestibular Perceptual Learning on Vestibular Thresholds and Balance
The intervention being studied is a minimal risk perceptual learning protocol delivered in an academic laboratory setting; the goal of the intervention is to improve the perception of passive whole-body tilts and/or translations…
- Trial name
- NCT05818787
- Testing
- Roll Tilt Training, Translation Training, Both Tilt and Translation Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Healthy Aging
Effects of Astaxanthin Supplementation on Metabolism, Cognition, and Physical Function in Older Adults
This study evaluated whether astaxanthin supplementation affects the body's ability to use fat for energy, cognitive performance, and physical function in healthy older adults.
- Trial name
- NCT07876193
- Testing
- Astaxanthin Oral Capsule
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of North Alabama
Facial Wrinkles, Skin Aging
Evaluation of MD60002 Device for Facial Skin Aging
This single-center, non-controlled, single-arm clinical study is designed to evaluate the performance and safety of the Class III investigational device MD60002 (composed of highly purified polynucleotides at 3%) for aesthetic…
- Conditions
- Facial Wrinkles, Skin Aging, Skin Imperfections
- Trial name
- CIP-02-25 (NCT07881926)
- Testing
- Device: MD60002
- Where
- Italy
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Promoitalia Group Spa
Healthy Volunteers, Aging, Healthy
Intervention Program for Psychological Well-Being in Institutionalized Older Adults Through Virtual Reality
This randomized controlled trial (N = 60) evaluates the acceptability and efficacy of an immersive virtual reality (IVR) intervention designed to enhance psychological well-being in older adults without cognitive impairment…
- Trial name
- RRCE (NCT07884435)
- Testing
- Active IVR Group, Passive IVR Goup
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Francisco Antonio Nieto Escámez
Ketosis, Resistance Exercise
Acute Effects of Ketone Monoester Co-Ingestion With Dietary Protein on Whole-Body Phenylalanine Oxidation, Phenylalanine Retention, and Myofibrillar Protein Breakdown Following Resistance Exercise in Older Males
The goal of this trial is to determine if ketone monoester supplementation in conjunction with protein supplementation in the post exercise period can augment whole-body protein metabolism following resistance exercise in older…
- Conditions
- Ketosis, Resistance Exercise, Dietary Protein, Aging
- Trial name
- KET-OLD-M (NCT07884513)
- Testing
- Ketone Monoester + Dietary Protein (KET+PRO), Dietary Protein (PRO), Resistance Exercise
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- McGill University
Auditory Perceptual Impairment, Aging
Using Nicotine to Reverse Age-related Auditory Processing Deficits
The present study will evaluate the effects of both aging and nicotine on psychophysical tasks and electrophysiological measures.
- Trial name
- Nicotine (NCT04971954)
- Testing
- Nicotine gum
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Photoaging, Skin Aging
AI-Personalized Skincare Regimen for Facial Photoaging in Women
The goal of this clinical study was to learn whether a skincare regimen personalized by an artificial intelligence (AI) skin-analysis tool improves signs of facial skin aging in women aged 35 to 65 with mild-to-moderate facial…
- Trial name
- NCT07879833
- Testing
- AI-personalized skin longevity regimen
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- MDalgorithms Inc.
Aging
Diaphragmatic Breathing Program In Older People
In the present study a program of respiratory physical therapy based on diaphragmatic breathing is applied in institutionalized old people, evaluating lung function parameters (FVC, FEV1, FEV1/FVC) and oxygen saturation.
- Trial name
- BP-OP (NCT03782779)
- Testing
- Breathing program and regular exercise, Regular Exercise
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Aging, Mild Cognitive Impairment
Implication of Cognitive Reserve in Non-pharmacological Intervention Outcomes
Cognitive reserve (CR) is defined as the gradual accumulation of neural resources and their adaptability (i.e., efficiency, capacity, flexibility) due to genetic and/or lifelong environmental factors that mitigate the cognitive…
- Conditions
- Aging, Mild Cognitive Impairment, Dementia With Lewy Bodies
- Trial name
- NCT06563453
- Testing
- transcranial alternating current stimulation
- Where
- Czechia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Skin Ageing, Healthy Ageing
Effects of a Multi-Targeted Oral Supplement on Skin, Hair, Sleep, Energy, Cognition, Libido and Epigenetic Biological Clock Age
This study evaluated the effects of a daily oral supplement regimen (Advanced ID Brain, Heart and Eye Omega Gel Capsules taken with Advanced ID Longevity and Collagen Complex Powder) on measures of skin condition, hair, sleep…
- Conditions
- Skin Ageing, Healthy Ageing, Effect of Oral Nutritional Supplementation on Skin, Hair, Sleep, Energy, Cognition and Sexual Wellbeing in Healthy Adults, Longevity
- Trial name
- IDF-AID-1 (NCT07827651)
- Testing
- Advanced ID
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- IDI Skincare Limited
Brow Ptosis, Dermatochalasis
Enhancing the Durability of Thread-Assisted Brow Suspension Through Upper Blepharoplasty-Assisted Ligament Release
This prospective clinical study aims to investigate whether combining upper blepharoplasty with limited release of the lateral brow-retaining ligaments improves the long-term effectiveness of barbed thread brow suspension.
- Conditions
- Brow Ptosis, Dermatochalasis, Periorbital Aging
- Trial name
- NCT07879456
- Testing
- Upper Blepharoplasty, Barbed Thread Brow Suspension, Lateral Brow-Retaining Ligament Release
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Muhammed Mustafa Demirok
Glucose Metabolism Disorders (Including Diabetes Mellitus), Cognitive Decline
Glucose Variability and Cognition in Prediabetes
This study examines the association of variability in glucose values over a 10-day period with cognitive function and AD risk markers among individuals with prediabetes, aged 50 or older.
- Conditions
- Glucose Metabolism Disorders (Including Diabetes Mellitus), Cognitive Decline, PreDiabetes, Aging
- Trial name
- NCT04201600
- Testing
- Continuous Glucose Monitoring System (CGMS)
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Aging
Continuous Connected Patient Care (CCPC), a Pilot Testing a Novel Device for Continuous Vitals Monitoring - Older Adults Department PHC
To confirm feasibility and accessibility of the CCPC Platform (Oxymotion, Bridge Health Solutions medication adherence software, CloudDX home kit) in two different environments - 1) hospital (Acute Care for Elderly Unit) and 2)…
- Trial name
- NCT06638060
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Aging, Endothelial Dysfunction
Fisetin for Improving Vascular Function in Older Adults: A Phase II Clinical Trial
Aging is associated with the development of vascular dysfunction, which increases the risk for cardiovascular disease. This clinical trial will assess if supplementation with the natural compound fisetin can improve vascular…
- Conditions
- Aging, Endothelial Dysfunction, Cellular Senescence
- Trial name
- NCT07871162
- Testing
- Fisetin
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Infertility Assisted Reproductive Technology, Ovarian Aging
Epigenetic Clock to Predict Ovarian Aging and Live Birth in ART
Epigenetic clocks based on DNA methylation estimate biological age and are associated with age-related conditions, but they have not been validated for female fertility.
- Trial name
- ARTCLOCK (NCT07875140)
- Testing
- Peripheral blood sampling for epigenetic age estimation
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Aging
Technical Development of Multi-Parametric Renocerebral MRI
The purpose of the study is to investigate the associations of the age-related changes in the brain, kidneys and cognitive performance in healthy adults by utilizing multiple anatomic and functional MRI methods along with a…
- Trial name
- NCT02831335
- Testing
- MRI, Group 4
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Chronic Disease, Aging
Compassionate Communities Neighbourhood Program
This study will evaluate a Compassionate Communities-based intervention aimed at reducing social isolation by mobilizing individuals to act on their health and social needs individually, and in collaboration with fellow members…
- Trial name
- WECCC-NHB (NCT03634163)
- Testing
- Neighbourhood exchange, Quality of Life Assessment
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McMaster University
Active Aging Individuals Aged 60 and Over
Physical Activity Promoting Active Aging
This project aims to explore the effects and underlying mechanisms of physical activity in promoting active aging among older adults.
- Trial name
- NCT07670208
- Testing
- Mind-body exercise, Multicomponent exercise, Online-based multicomponent exercise
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yu Wang
Aging
Effects of Otago Exercise Combined With Short-Foot Exercise in Older Adults
The Otago Exercise Programme is a multicomponent exercise approach targeting strength, balance, and mobility in older adults. Short-foot exercises are designed to improve intrinsic foot muscle activation and medial longitudinal…
- Trial name
- NCT07870486
- Testing
- Otago Exercise Programme, Otago Exercise Programme + Short-Foot Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pamukkale University