Clinical trials: Agitated Behaviour
Agitation, Emergence
Intramuscular Ketamine Effect on Postnasal Surgery Agitation
Emergence agitation (EA) is a common complication after nasal surgery. In this study, we aimed to investigate the effect of intramuscular ketamine on EA following septoplasty and open septorhinoplasty (OSRP) when administered at…
- Trial name
- NCT05313659
- Testing
- Ketamine Hydrochloride
- Where
- Jordan
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Jordanian Royal Medical Services
Agitation
Effect of Deksmedetomidine and Remifentanil in Extubation Agitation
To compare the effect of two different agents deksmedetomidine, remifentanil and placebo, agitation and recovery condition, on nasal septum operation.
- Trial name
- EA (NCT02104297)
- Testing
- deksmedetomidine, Remifentanil, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Agitated; State, Acute Reaction to Stress, Agitation,Psychomotor
Mindful Melody: Feasibility of Implementing Music Listening on an Inpatient Psychiatric Unit and Its Relation to the Use of As Needed Medications for Acute Agitation
In this quality improvement project, our objectives were to assess the feasibility and effectiveness of using music as an adjunct to or replacement of pharmacological interventions for patient agitation on an inpatient…
- Trial name
- NCT04514432
- Testing
- Music
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Agitation
Naturalistic Adasuve Clinical Trial Study
There is limited information on the best psychoactive medication to treat agitated patients in the emergency department. The intent of this study is to fill in knowledge gaps in the current practice of treating psychiatric…
- Trial name
- NCT02877108
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mt Sinai Hospital, Chicago
Restless Legs Syndrome, Sleep Quality
Restless Legs Syndrome and Sleep Quality in Pes Planus
Pes planus, also known as flatfoot, is a common foot deformity that can affect the biomechanics of the lower limbs. However, its relationship with neurological conditions has not been studied extensively.
- Conditions
- Restless Legs Syndrome, Sleep Quality, Pain, Quality of Life
- Trial name
- FLAT-RLS (NCT07117591)
- Where
- Turkey (Türkiye)
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Bozok University
Neurocognitive Disorders, Post Operative Delirium
Safe Brain Initiative, Operationalizing Precision Anaesthesia
Perioperatively, patients experience an unnecessarily high level of side effects associated with their treatment. These side effects include nausea, severe pain, anxiety, and stress.
- Conditions
- Neurocognitive Disorders, Post Operative Delirium, Pain, Nausea
- Trial name
- SBI (NCT05765162)
- Testing
- Patient reported ourcomes
- Where
- Denmark
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Dementia
Reducing Agitation in People With Dementia: the Customized Activity Trial
Over 5 million Americans have Alzheimer's disease or a related dementia, a progressive and irreversible neurodegenerative condition, affecting also close to 15 million family caregivers (CG).
- Trial name
- TAP (NCT01892579)
- Testing
- Tailored Activity Program, Home Safety and Education Program
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Suicide, Depression
Cranial Electric Stimulation to Modify Suicide Risk Factors in Psychiatric Inpatients.
This pilot study aims to investigate whether a treatment called cranial electric stimulation or CES can decrease risk factors for suicide. The specific CES device we will use is called Alpha-Stim®.
- Conditions
- Suicide, Depression, Anxiety, Insomnia
- Trial name
- NCT02846740
- Testing
- Alpha-Stim®., Montgomery-Åsberg Depression Rating Scale, Hamilton Anxiety Rating Scale, The Pittsburgh Sleep Quality Index and agitated behavior Scale
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Depressive Disorder, Mood Disorder
Progestin (Progesterone-Like Hormones) Induced Dysphoria (Depressed Mood, Irritability, Anxiety)
Often women are prescribed hormone replacement therapy (HRT) during the perimenopause or menopause. Hormone replacement therapy includes both estrogen and progesterone.
- Conditions
- Depressive Disorder, Mood Disorder, Psychomotor Agitation
- Trial name
- NCT00001770
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Agitated; State, Acute Reaction to Stress
Preemptive Chlorepheniramine Maleate Reducing Postoperative Agitation
The aim of the study is to identify the role of preoperative chlorepheniramine maleate on alleviating or reducing the severity of postoperative agitation following FESS procedures.
- Trial name
- NCT04293081
- Testing
- Preemptive chlorepheniramine maleate intravenous injection, normal saline
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Psychomotor Agitation
The Effect of Dexmedetomidine on Emergence Agitation in Children Undergoing a Surgery Under Desflurane Anesthesia
After genernal anesthesia using sevoflurane or desflurane, the investigators can observe many cases of agiation (over 80%) and despite of no report of long-term complication, agitation is a big issue in PACU for doctors and…
- Trial name
- NCT01578161
- Testing
- Dexmedetomidine, 0.9% Normal Saline
- Where
- South Korea
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Delirium, Epileptics
Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy
To examine the effects of haloperidol, chlorpromazine, valproic acid and placebo, in conjunction with standardized non-pharmacologic interventions, in the first line treatment of agitated delirium in hospitalized patients with…
- Conditions
- Delirium, Epileptics, Neuroleptics
- Trial name
- NCT05431595
- Testing
- Haloperidol, Chlorpromazine, Valproate
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Obstructive Sleep Apnea (OSA), Insomnia
Validating the Use of a Subjectively Reported Sleep Vital Sign
Sleep disorders are commonly under-recognized in the primary care setting and available screening tools are often are limited. The study inestigators hypothesize that the use of a novel subjective sleep vital sign (VS) will…
- Conditions
- Obstructive Sleep Apnea (OSA), Insomnia, Restless Leg Syndrome (RLS), Hypersomnia Type; Sleep Disorder
- Trial name
- SVS (NCT03018912)
- Testing
- Sleep VS
- Where
- United States
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Agitation,Psychomotor, Haloperidol Causing Adverse Effects in Therapeutic Use
Inhaled Loxapine vs Intramuscular (IM) Haloperidol + Lorazepam for Agitation
The primary objective of this study is to determine the noninferiority of inhaled loxapine compared to intramuscular haloperidol/lorazepam on agitation reduction at 120 minutes.
- Conditions
- Agitation,Psychomotor, Haloperidol Causing Adverse Effects in Therapeutic Use, Lorazepam Causing Adverse Effects in Therapeutic Use, Loxapine Causing Adverse Effects in Therapeutic Use
- Trial name
- loxapine (NCT03110900)
- Testing
- Haloperidol + lorazepam, Loxapine
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Alzheimer's Dementia With Behavioral Disturbance
Acupuncture to Reduce Anxiety in Alzheimer's Disease (AD) and AD Related Dementias
The purpose of this study is to investigate the influence of acupuncture on heart rate variability, skin conductance (sweating), and rated behavioral expression of agitation, irritability, and anxiety and mood in qualifying…
- Trial name
- NCT03814382
- Testing
- Acupuncture needle
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Akathisia
Akathisia (Restless Legs Syndrome) in People With Schizophrenia and Mental Retardation
Akathisia is a movement disorder that is often a side effect of certain psychiatric drugs. People with akathisia are unable to sit or keep still, complain of restlessness, fidget, rock from foot to foot, and pace.
- Trial name
- NCT00065286
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Supraventricular Tachycardia
Simulation of Adenosine Push Methods for Treatment of SVT Using Agitated Saline Visualized by Ultrasound
Supraventricular tachycardia (SVT) is an abnormally fast heart rhythm arising from improper electrical activity in the upper part of the heart.
- Trial name
- NCT04051541
- Testing
- Agitated saline push
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Psychomotor Agitation, Behavioral Disorder
Clinical Trial of Peer Support in the ED (PCORI)
The purpose of this study is to conduct a clinical trial that tests the acceptability, fidelity, and feasibility of a peer support modified intervention for agitation management within the emergency department.
- Trial name
- NCT06556069
- Testing
- Peer-Support Enhanced Agitation Code Team (PACT)
- Where
- United States
- Volunteers
- 57,870 people, healthy volunteers welcome
- Sponsor
- Yale University
Agitation, Emergence
Single Bolus Dose of Ketodex Versus Ketofol For Prevention Of Emergence Agitation In Adults Undergoing Nasal Surgeries
emergence agitation is seen in around 68% after nasal surgeries. Agitated patients needs more staff and nurses to control their abnormal movement which leads to self extubation , removal of catheters and bruises in the…
- Trial name
- NCT04018157
- Testing
- "Ketamine" and "dexmedetomidine" and "propofol" and "0.9%saline"
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Advanced Cancer, Delirium
Delirium Recall in Advanced Cancer Patients
Primary Objectives: 1. To determine the proportion of patients who experience partial or complete recollection of symptoms of delirium and the level of distress associated with this recall. 2.
- Trial name
- NCT00493714
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center