Clinical trials: Air Embolism
Air Embolism, Air Leakage
Factors Increasing Air Burden in Intravenous Tubing
There is widespread acceptance that air in intravenous (IV) fluid tubing (lines) can pose a significant risk to patients.1 A rigorous literature search regarding sources of this air identified only anecdotal and non-clinical work…
- Conditions
- Air Embolism, Air Leakage, Air Burden
- Trial name
- NCT03723408
- Testing
- ClearLine IV (formerly, AirPurge)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- ClearLine MD
Inflammation, Coagulation
Intervention Study on the Health Impact of Air Filters in Chinese Adults
This study aimed to evaluate whether a short-term indoor air purifier intervention improves cardiopulmonary health based on a randomized double-blind crossover trial
- Conditions
- Inflammation, Coagulation, Blood Pressure, Pulmonary Function
- Trial name
- NCT02239744
- Testing
- Air purifiers
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Fudan University
Heart Failure, Ventricular Dysfunction
The Use of CoSeal (Sealant Agent) in Patients During Left Ventricular Assist Device Surgery
The purpose of this study is to evaluate the use of a device called CoSeal™. CoSeal™ is an FDA approved synthetic (man-made) surgical sealant which is currently used to help stop leaks in blood vessels during surgery.
- Trial name
- NCT01605019
- Testing
- CoSeal, BioGlue® Surgical Adhesive
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- The Methodist Hospital Research Institute
Pneumothorax Iatrogenic Postprocedural, Air Embolism as A Complication of Medical Care
Complications After CT-guided Lung Biopsies at St. Olavs Hospital
At St. Olavs Hospital, a prospective collection of data on complications related to CT-guided lung biopsies has been conducted over several years as part of quality control study.
- Conditions
- Pneumothorax Iatrogenic Postprocedural, Air Embolism as A Complication of Medical Care, Hemoptysis
- Trial name
- KELSO (NCT07528170)
- Testing
- CT-guided needle biopsy of lung nodule
- Volunteers
- 1,200 people
- Sponsor
- St. Olavs Hospital
Coronary Artery Disease, Acute Cerebrovascular Accident
Incidence of Acute Cerebrovascular Events Using Either Minimized or Standard Cardiopulmonary Bypass Circuit
The prospective, randomized, two centre study investigates acute cerebrovascular events during extracorporal circulation and the early post operative outcome when using either the minimized cardiopulmonary bypass circuit…
- Conditions
- Coronary Artery Disease, Acute Cerebrovascular Accident, Intracranial Embolism, Embolism, Air
- Trial name
- ROCsafeTM (NCT00862160)
- Testing
- ROCsafeTM
- Where
- 2 sites in Germany
- Volunteers
- 64 people
- Sponsor
- Hannover Medical School
Embolism, Air
Gas Embolism With Use of Argon Plasma Coagulation
The purpose of this study is to use transesophageal echocardiography (TEE) to determine the incidence, severity, and clinical significance of gas bubbles during argon plasma coagulation (APC).
- Trial name
- NCT00676858
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Beth Israel Deaconess Medical Center
Embolism Vein, Air Embolism
Study on the Incidence and Risk Factors of Systemic Arterial Gas Embolism in Bronchoscopy Procedures
Systemic Arterial Gas Embolism (SAGE) is a rare but fatal complication characterized by the accidental entry of gas into the left heart system, which then travels through the systemic arterial circulation, leading to embolisms in…
- Trial name
- NCT07555990
- Where
- China
- Volunteers
- 3,258 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Hemodialysis Complication, Air Embolism
Reduction of Microemboli of Air Using a New Developed Air Trap (EmbolessTM) During Haemodialysis
During hemodialysis (HD) the blood of the patient pass an extracorporeal circuit that contains a dialyzer for rinsing and a venous chamber (air trap) to prevent from air embolism through the return blood into the patient.
- Conditions
- Hemodialysis Complication, Air Embolism, Extracorporeal Circulation; Complications
- Trial name
- NCT06168539
- Testing
- Emboless, Standard
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Umeå University
Pituitary Adenoma
Semi-sitting Versus Supine Position in Endoscopic Skull Base Surgery
This study is to prospectively compare the standard supine (control group) and the semi-sitting position (head elevation of 30°; intervention group) in endoscopic endonasal pituitary surgery.
- Trial name
- PosESS (NCT04584866)
- Testing
- Endonasal endoscopic pituitary surgery in semi-sitting position, Endonasal endoscopic pituitary surgery in supine position
- Where
- Switzerland
- Volunteers
- 54 people
- Sponsor
- University Hospital, Basel, Switzerland
Air Embolism, Neurological Damage
Insufflation of Carbon Dioxide During Cardiac Surgery as Prevention Neurologic Complications
Effect of intraoperative insufflation of carbon dioxide on the neurologic complications in the early postoperative period after open cardiac surgery.
- Trial name
- NCT02340741
- Testing
- conventional prophylaxis of aeroembolism, conventional prophylaxis plus CO2 insufflation, cardiac surgery with opening of heart chambers
- Where
- Russia
- Volunteers
- 334 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Embolism Air Post-Procedural
CO2 Field Saturating Alternative Techniques Comparison
Prospective Randomized study comparing three strategy of deairing (NO CO2 insufflation, CO2 insufflation with non specific cannula, CO2 insufflation with commercial dedicated diffuser) as regarding Time to Complete Deairing…
- Trial name
- NCT03961425
- Testing
- NO CO2, CO2 Cannula, CO2 Cardia
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Cardiochirurgia E.H.
Oxidative Stress, Inflammation
Effect of Dietary Supplemental Fish Oil in Alleviating Health Hazards Associated With Air Pollution
This study aims to evaluate whether dietary supplementation with fish oil can protect against the cardiopulmonary alterations linked to air pollution
- Conditions
- Oxidative Stress, Inflammation, Blood Pressure, Vasoconstriction
- Trial name
- NCT03255187
- Testing
- Fish oil supplementation, Sunflower seed oil supplementation
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fudan University
Air or Gas Embolism, Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy Registry
The purpose of the Hyperbaric Oxygen Therapy Registry (HBOTR) is to provide real world patient outcome and side effect information from electronic health records submitted to a specialty specific hyperbaric registry as part of…
- Conditions
- Air or Gas Embolism, Carbon Monoxide Poisoning, Clostridial Myositis and Myonecrosis (Gas Gangrene), Crush Injury, Compartment Syndrome & Other Acute Traumatic Ischemias
- Trial name
- HBOTR (NCT02483650)
- Volunteers
- 5,000 people
- Sponsor
- U.S. Wound Registry
Deep Vein Thrombosis
Non-invasive Venous Air Plethysmography Assessment of Venous Hemodynamics in Patients Suspected Deep Venous Obstruction Used in Conjunction With Intermittent Pneumatic Compression.
The purpose of this research is to measure changes in venous blood flow with an air-filled bladder under an intermittent pneumatic compression device cuff (used to prevent deep venous thrombosis) or venous diagnostic device cuff…
- Trial name
- NCT06519435
- Testing
- Mayo Dopplex ABIlity, Intermittent Pneumatic Compression (IPC)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Mayo Clinic
Extracorporeal Circulation; Complications, Air Embolism
Comparing Air Embolic Load in Two Venous Cannulation Methods, 40 Patients Undergoing Elective Valve Surgery.
The goal of this single center prospective controlled observational and interventional trial is to investigate and compare origin of air emboli when different venous cannulation methods is used in patients undergoing cardiac…
- Trial name
- NCT05820828
- Testing
- Volume control
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Petronella Torild
Pulmonary Embolism
Air Versus Oxygen for Intermediate-Risk Pulmonary Embolism (AIRE)
The primary objective is to evaluate the efficacy of the treatment with supplementary oxygen added to conventional anticoagulant treatment in patients with Intermediate-risk pulmonary embolism.
- Trial name
- AIRE (NCT04003116)
- Testing
- Oxygen gas
- Where
- 7 sites in Spain
- Volunteers
- 70 people
- Sponsor
- Ministry of Health, Spain
Anemia, Cognitive; Disorder, Due to General Medical Condition
Haemo-autologous Antegrade Repriming (HAR) as Minimum Impact Perfusion Strategy for Cardiopulmonary Bypass
Haemo-autologous Antegrade Repriming (HAR) is a procedure based in the combination of evidence proven measures designed to reduce the haemodilution caused by establishing the cardiopulmonary bypass (CPB) during cardiac surgery.
- Conditions
- Anemia, Cognitive; Disorder, Due to General Medical Condition, Embolism, Air, Transfusion
- Trial name
- HARjbm1 (NCT03720184)
- Testing
- HAR
- Where
- Spain
- Volunteers
- 116 people
- Sponsor
- Juan Blanco Morillo
Heart Disease
The Effect of a Retrofit Particle Trap on the Vascular Effects of Diesel Exhaust Inhalation
The purpose of this study is to determine whether a retrofit particle trap can reduce the adverse vascular responses to diesel exhaust inhalation
- Trial name
- NCT00745446
- Testing
- Forearm Venous Occlusion Plethysmography
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Aortic Valve Disorder
CO2 Versus Lund De-airing Technique in Heart Surgery
To evaluate which of the two de-airing methods (CO2 insufflation vs. Lund de-airing technique) can shorten the left heart de-airing time and prevent or minimize cerebral air emboli during open surgery involving exposure of the…
- Trial name
- NCT00934596
- Testing
- Lund de-airing technique, carbon-dioxide insufflation
- Volunteers
- 20 people
- Sponsor
- Lund University
Patients Who Underwent Percutaneous Lung Biopsy Under CT Guidance, Patients Who Presented Systemic Air Embolism After Percutaneous Lung Biopsy Under CT Guidance Depicted at the Time of the Procedure on a Whole Thoracic CT
Systemic Air Embolism After CT-guided Lung Biopsy
Systemic air embolism is traditionally considered as an extremely rare complication of percutaneous lung biopsy. Current literature includes mainly case reports or small case series of SAE.
- Trial name
- SAE (NCT03360084)
- Testing
- Percutaneous lung biopsy under CT guidance
- Where
- France
- Volunteers
- 559 people
- Sponsor
- University Hospital, Montpellier