Clinical trials: Air Pollution Exposure
Exposure to Environmental Pollution, Non-occupational
Interaction Effects of Temperature and Ozone
Purpose: The purpose of this protocol is to understand how individuals respond to the air pollutant ozone at elevated temperatures.
- Trial name
- TROPICOZ (NCT01981135)
- Testing
- Clean Air, Ozone
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Healthy Women
Effect of an Antioxidant Dietary Supplement on Skin Radiance
A randomized, double-blind, placebo-controlled study evaluating the effects of an oral antioxidant dietary supplement on skin radiance in women exposed to urban air pollution.
- Trial name
- NCT07793123
- Testing
- Antioxidant Supplement
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Robertet SA
Lung Diseases
Assessment of Exposures of the Mother-infant Pair to the Air Pollution of São Paulo
A single group of pregnant women who was analyzed in the first and in the third trimesters of pregnancy
- Trial name
- NCT02807038
- Testing
- Lung function test
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Healthy Individuals, Allergic Rhinitis
Health Effects of Wood Smoke and Traffic-Related Air Pollution Exposures: a Necessary Comparison
Accumulating evidence demonstrates that breathing air pollutants leads to devastating increases in sickness and death worldwide over time.
- Trial name
- WADE (NCT06749093)
- Testing
- Filtered Air (FA), Wood Smoke (WS), Diesel Exhaust (DE)
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Oxidant Imbalance, Pulmonary Function
In Utero Household Air Pollution Exposure and Lung Development in Ghana
Household air pollution from cook stoves using solid fuels dominates total population air pollution exposures. Females and young children are disproportionately affected as they either perform or are present for the majority of…
- Trial name
- NCT02200289
- Where
- Ghana
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Allergies
Effects of Co-Exposure to Air Pollution and Allergen
The investigators are investigating the effects of combined exposures to diesel exhaust and allergens on lung function and on the immune system.
- Trial name
- NCT01792232
- Testing
- Allergen, Saline
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Exposure to Pollution, Heart Failure
Effects of Air Pollution Exposure Reduction by Filter Mask on Heart Failure
Exposure to air pollution is associated with increase in cardiovascular morbidity and mortality. Controlled human exposure studies have demonstrated impaired vascular function and heart rate variability on healthy volunteers.
- Trial name
- NCT01960920
- Testing
- Filtered diesel exhaust, Unfiltered diesel exhaust, Clean air
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- InCor Heart Institute
Pulmonary Disease, Chronic Obstructive, Airway Disease
Innate Immunity in Ozone-induced Airway Inflammation in COPD
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States. Patients with COPD are routinely exposed to indoor and outdoor air pollution, which appears to cause escalation of their…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Airway Disease, COPD Exacerbation, Pollution; Exposure
- Trial name
- CO3PD (NCT04669743)
- Testing
- Ozone exposure
- Where
- 3 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy
Sympathetic Nerve Activation Evoked by Diesel Exhaust Exposure
The adverse effects of air pollution on cardiovascular and respiratory health have been demonstrated in an extensive series of epidemiological, observational and experimental studies.
- Trial name
- NCT02892279
- Testing
- Diesel exhaust exposure
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Umeå University
Ozone Exposure During Rest and Exercise
Susceptibility of Cardiorespiratory Responses to Ozone During Cycling Exercise
Ground level ozone (O3) is a common airborne pollutant that is well recognized to cause negative respiratory symptoms and impair pulmonary function.
- Trial name
- NCT05473000
- Testing
- Exercise, Ozone, Room air
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Exposure to Polluted Air
Association Between PM2.5 and Ferroptosis
This cohort study aims to discover the possible effects of PM2.5 exposures on the Nrf2- dependent ferroptosis pathway. This observational cohort's main question is whether PM2.5 exposures will affect the Nrf2- dependent…
- Trial name
- NCT05753332
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northern Jiangsu People's Hospital
Sleep Quality
Mitigation of Health Effects in Pregnant Women by Reducing Exposure to Heat and Air Pollution
The goal of this clinical trial is to assess the effectiveness of an intervention (combination of behavioural recommendations and technical measures) in reducing personal exposure to heat and air pollution and related health…
- Trial name
- ISMED CLIM PW (NCT07609433)
- Testing
- Heat intervention, Heat and air pollution mitigation intervention
- Where
- 3 sites in Cyprus, Italy
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Occupational Exposure
Air Quality Monitoring and Health Surveillance of Workers in the Photocopier Units
To monitor air quality in selected photocopier units and to assess the health status of workers who are exposed to emissions from photocopiers.
- Trial name
- NCT01289184
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Avinashilingam Deemed University
Asthma Acute, Respiratory
Children's Health, Respiratory Inflammation and Short-term Air Pollution
The goal of this study is to see if physical activity in high air pollution is worse than rest in high air pollution.
- Trial name
- CHERISH (NCT07431021)
- Testing
- science lesson, PE Lesson
- Where
- United Kingdom
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Cognitive Function, Cardiopulmonary Function
Commuter Air Pollution Intervention Study
Traffic related air pollution is a well-recognised and much studied contributor to smog and is linked to a number of adverse health outcomes.
- Conditions
- Cognitive Function, Cardiopulmonary Function, Saliva Stress Hormones, Air Pollution Exposure
- Trial name
- CAPI (NCT02277002)
- Testing
- Cabin Air Filtration
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Health Canada
Health Effects of Ambient Air Pollution
Effects of Omega-3 Fatty Acids in Ambient Air Pollution Exposure in Healthy Adults
This observational study recruits healthy individuals who have been routinely taking high amount (at least 3 g/wk) of dietary eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and those who don't, and examines the…
- Trial name
- PISCES (NCT02921048)
- Testing
- omega-3 fatty acids
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- U.S. EPA Human Studies Facility
Coronary Disease
The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin
The purpose of this study is to identify the role of endothelin 1 (a natural vasoconstrictor) in the adverse vascular effects demonstrated after exposure to air pollution
- Trial name
- NCT00745693
- Testing
- Endothelin-1, BQ-123 and BQ-788
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Pollution; Exposure, Health Behavior
Improving the Behavioural Impact of Air Quality Alerts
The evidence shows that adherence to air quality advice to adopt protective behaviours during pollution episodes is suboptimal, and that the traditional strategy of simply informing people about high pollution episodes is not…
- Trial name
- NCT03552198
- Testing
- Alternative health advice
- Where
- United Kingdom
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- King's College London
Cardiovascular Morbidity
Experimental Exposure to Air Pollutants and Sympathetic Nerve Activity in Human Subjects
The primary hypothesis of the study is that in healthy elderly subjects experimental exposure to air pollutants increases sympathetic nervous system activity compared with sham (clean air) exposure.
- Trial name
- Particles (NCT01914783)
- Testing
- ultrafine particles, ultrafine particles and ozone, clean air
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Healthy Adults
Statins Against Bushfire Smoke
The goal of this clinical trial is to test whether statins can protect the heart and brain from the biological stress and inflammatory responses caused by breathing bushfire smoke in healthy adult volunteers aged 18-64 years.
- Trial name
- SABS (NCT07462715)
- Testing
- Atorvastatin
- Where
- Australia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Menzies Institute for Medical Research