Clinical trials: Air Pollution Exposure
Physical Inactivity, Pollution; Exposure
Air Pollution and Physical Activity Study
This is a small pilot intervention tria lfor exercise and air pollution.
- Trial name
- PARC (NCT06386055)
- Testing
- Active exercise
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Air Pollution, Pollution; Exposure
Modification of Ambient Air Pollution Exposure and Cardiopulmonary Outcomes by Socioeconomic Status and Nutrition
The goal of this observational study is to compare the effects of air pollution exposure and nutrition between neighborhoods with high and low social vulnerability scores.
- Conditions
- Air Pollution, Pollution; Exposure, Nutrition, Healthy
- Trial name
- SENSE (NCT05843370)
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Allergies
Air Pollution and Allergens - Attenuation of Health Effects Particle Reduction
The study probes the effects of combined exposures to diesel exhaust and allergens on lung function and on the immune system, specifically focusing on the ability of a particle depletion technique to attenuate effects we and…
- Trial name
- DE3 (NCT02017431)
- Testing
- Allergen, Saline, Particle depleted diesel exhaust
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Air Pollution Exposure, Oxidative Stress
Savannah Environmental Nutrition Study (SENS): Nutrition Intervention to Reduce Air Pollution-Related Airway Inflammation and Oxidative Stress
This pilot clinical trial will evaluate the feasibility and potential health effects of a nutrition-based intervention among adults living in communities affected by air pollution near the Port of Savannah, Georgia.
- Conditions
- Air Pollution Exposure, Oxidative Stress, Airway Inflammation
- Trial name
- NCT07797413
- Testing
- Antioxidant- and Nutrient-Rich Food-Based Nutrition Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Georgia Southern University
Pollution; Exposure, HTN
The Effect of Personal Protective Aids on Hypertension and Diabetes in People Exposed to High Levels of Air Pollution
This is a randomized controlled trial to evaluate personal protective aids (air purifier and N95) as a therapeutic measure in people with hypertension and diabetes exposed to high levels of PM2.5 in India.
- Conditions
- Pollution; Exposure, HTN, Diabetes Mellitus
- Trial name
- NCT04854187
- Where
- India
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Sleep Quality
Mitigation of Health Effects in Pregnant Women by Reducing Exposure to Heat and Air Pollution
The goal of this clinical trial is to assess the effectiveness of an intervention (combination of behavioural recommendations and technical measures) in reducing personal exposure to heat and air pollution and related health…
- Trial name
- ISMED CLIM PW (NCT07609433)
- Testing
- Heat intervention, Heat and air pollution mitigation intervention
- Where
- 3 sites in Cyprus, Italy
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Non-smoking, Healthy Adults
Effect of Short-term Portable Air Purifier Use on Occupant Health Indicators
The purpose of this research project is to examine whether short-term use of portable air pollution filtration can result in changes in indoor airborne pollutants and impact on cardiovascular and respiratory health outcomes of…
- Trial name
- NCT02736487
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Ozone Exposure During Rest and Exercise
Susceptibility of Cardiorespiratory Responses to Ozone During Cycling Exercise
Ground level ozone (O3) is a common airborne pollutant that is well recognized to cause negative respiratory symptoms and impair pulmonary function.
- Trial name
- NCT05473000
- Testing
- Exercise, Ozone, Room air
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Heat Strain
Mitigation of Health Effects in Outdoor Workers by Reducing Exposure to Heat and Air Pollution
The goal of this clinical trial is to assess the effectiveness of an intervention (combination of behavioural recommendations and technical measures) in reducing personal exposure to heat and air pollution and related health…
- Trial name
- ISMED-CLIM OW (NCT07634952)
- Testing
- Heat intervention, Heat and air pollution mitigation intervention
- Where
- 2 sites in Greece, Spain
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Coronary Heart Disease
Myocardial Ischaemia After Exposure to Diesel Exhaust
Exposure to particulate air pollution is associated with increases in cardiovascular mortality and morbidity. The pathophysiological mechanisms underlying this observation are emerging, and exposure to particulate air pollution…
- Trial name
- MIDAS (NCT01661582)
- Testing
- CT/PET Myocardial Perfusion Imaging using O-15 water, Coronary blood flow measured by doppler echocardiography
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Air Pollution, Pregnancy
Immune Tolerance Dysfunction in Pregnancy Due to Ambient Air Pollution Exposure
The purpose of this project is to study the effects of air pollution toxicants on pregnant mothers' immune health during and after pregnancy.
- Trial name
- NCT04549142
- Testing
- There is no intervention
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Stanford University
Air Pollution
The Role of Macrophage Activation in Lung Injury Following Ozone Exposure
The purpose of the study is to better understand the mechanisms of lung injury from ozone exposure. Subjects will participate in two exposure sessions: filtered air and 0.2 ppm ozone.
- Trial name
- NCT05794087
- Testing
- Clean Air, Ozone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Pollution; Exposure, Hypertension
Solar Lighting to Reduce Indoor Air Pollution in Rural Uganda
This study evaluates the impact of a solar lighting system on kerosene lamp use, levels of indoor air pollution, and health in women living in rural Uganda.
- Conditions
- Pollution; Exposure, Hypertension, Pollution Related Respiratory Disorder
- Trial name
- NCT03351504
- Testing
- Solar lighting system
- Where
- 2 sites in United States, Uganda
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pollution; Exposure, Health Behavior
Improving the Behavioural Impact of Air Quality Alerts
The evidence shows that adherence to air quality advice to adopt protective behaviours during pollution episodes is suboptimal, and that the traditional strategy of simply informing people about high pollution episodes is not…
- Trial name
- NCT03552198
- Testing
- Alternative health advice
- Where
- United Kingdom
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- King's College London
Exposure to Polluted Air
Association Between PM2.5 and Ferroptosis
This cohort study aims to discover the possible effects of PM2.5 exposures on the Nrf2- dependent ferroptosis pathway. This observational cohort's main question is whether PM2.5 exposures will affect the Nrf2- dependent…
- Trial name
- NCT05753332
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northern Jiangsu People's Hospital
Psychological Stress, Psychological Well-Being
DivAirCity Social Health Survey
To reduce stress among urban residents, the consortium members of the European Council Horizon 2020 research program DivAirCity install different stress reducing, noise reducing and air quality improving means in the five cities…
- Conditions
- Psychological Stress, Psychological Well-Being, Pollution; Exposure
- Trial name
- DivAirCitySH (NCT06274229)
- Testing
- Air pollution and noise reducing installations
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Vascular Endothelium
Health Effects of Biodiesel Exhaust Exposure
Urban air pollution is a major contributor to greenhouse gases and has been shown to increase cardiovascular mortality and morbidity.
- Trial name
- BD100 (NCT01883466)
- Testing
- Forearm venous occlusion plethysmography study
- Where
- Sweden
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Umeå University
Environmental Exposure, Ozone
Lung Mucus Hypersecretion and NQO1
The research plan proposes translational studies in relevant animal models and human subjects in order to identify host (genetic) susceptibility factors that confer vulnerability to the prototypal air pollutant, ozone.
- Conditions
- Environmental Exposure, Ozone, Air Pollution, Genetic Susceptibility
- Trial name
- NCT00729352
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Environmental Exposure, Health Behavior
The Barts Charity Children's Environmental Health Clinic
The study will be based from a newly formed NHS service, the children's environmental health service. Participants will be children with a known chronic respiratory condition.
- Conditions
- Environmental Exposure, Health Behavior, Asthma in Children, Environmental Illness
- Trial name
- BCCEHC (NCT06447974)
- Testing
- Exposure mitigations
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Exposure to Polluted Air
Neurological Symptoms and Findings in Individuals Exposed to Indoor Air Pollutants
To evaluate neurological findings with TSPO-PET and MRI in patients who have been exposed to indoor air pollutants and have potentially neurological symptoms.
- Trial name
- NCT05111678
- Where
- Finland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital