Clinical trials: Airway Extubation
Airway Extubation, Ventilator Weaning
Mechanical Ventilation Reconnection for One Hour After Spontaneous Breathing Trial
The aim of this study is to evaluate the feasibility to perform a future larger clinical trial to analyze whether the mechanical ventilation reconnection for 1 hour after a successful spontaneous breathing trial reduces the risk…
- Trial name
- NCT05999526
- Testing
- Reconnection to mechanical ventilation for 1 hour, Direct extubation
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Centro Hospitalar Unimed de Joinville
Respiratory Failure
Non-invasive Ventilation for Extubation Success in Infants Less Than 1,250 Grams
In preterm infants, endotracheal mechanical ventilation is well known to cause various forms of lung injury including volutrauma, barotrauma and oxytrauma - collectively known as ventilator-induced lung injury (VILI).
- Trial name
- NOVEL (NCT02051491)
- Testing
- BP-NCPAP, NIHFV
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Mount Sinai Hospital, Canada
Endotracheal Extubation, Airway Obstruction
Efficacy Study of a Novel Device to Clean the Endotracheal Tube
The purpose of this study is to evaluate the in-vivo efficacy of a novel device (endOclear) for cleaning the endotracheal tube (ETT) lumen from secretions.
- Conditions
- Endotracheal Extubation, Airway Obstruction, Airway Control, Pneumonia, Ventilator-Associated
- Trial name
- NCT01765530
- Testing
- ETT cleaning maneuver
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Massachusetts General Hospital
Respiratory Distress Syndrome
High Flow Nasal Cannula in Comparison With Nasal Continuous Positive Airway Pressure in the Management of Respiratory Distress Syndrome
To compare the primary outcome, failure of extubation defined by the need for re-intubation and mechanical ventilation within 5 days of initial extubation and secondary outcomes, morbidities and mortality after using of heated…
- Trial name
- NCT02587832
- Testing
- HHHFNC, NCPAP
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Sidra Medicine
Robotic Surgical Procedures, Airway Extubation
Site of Tracheal Extubation and Operating Room Efficiency During Robot-assisted Surgery
This study aims to evaluate the impact of different extubation strategy on the occupancy time of operating room (OR) and the incidence of adverse events and quality of recovery after robotic-assisted surgery.
- Conditions
- Robotic Surgical Procedures, Airway Extubation, Operating Rooms, Anesthesia Recovery Period
- Trial name
- NCT07332806
- Testing
- Extubation in post-anesthesia care unit (PACU), Extubation in operating room (OR)
- Where
- China
- Volunteers
- 218 people
- Sponsor
- Peking University First Hospital
Extubation Failure
Bubble Continuous Positive Airway Pressure (CPAP) With Conventional CPAP for Extubation in Preterm Infants
The objective of this study is to evaluate whether CPAP delivered by bubble CPAP resulted in a greater proportion of infants being successfully extubated when compared with management with ventilator derived CPAP.
- Trial name
- NCT00979433
- Testing
- Bubble CPAP, Conventional CPAP
- Where
- India
- Volunteers
- 32 people
- Sponsor
- All India Institute of Medical Sciences
Delayed Emergence From Anesthesia
Recovery Profile Comparison Between Remifentanil-propofol or Desflurane Anesthesia Monitored With Bispectral Index.
Bispectral monitoring anesthesia with remifentanil-desflurane has a better post-operative recovery than remifentanil-propofol.
- Trial name
- NCT02631525
- Testing
- Desflurane, Propofol
- Volunteers
- 40 people
- Sponsor
- Federal University of Minas Gerais
Complications, Pulmonary
Laryngeal Mask Airway Facilitates a Safe and Smooth Emergence From Anesthesia in Patients Undergoing Craniotomy
Stabilizing hemodynamic and reducing pulmonary complications during extubation with switching endotracheal tube to laryngeal mask in craniotomies
- Trial name
- NCT05253404
- Testing
- Ambu® AuraOnce™ Disposable Laryngeal Mask
- Where
- Taiwan
- Volunteers
- 62 people
- Sponsor
- Chang Gung Memorial Hospital
Morbid Obesity
Effect of Boussignac CPAP Ventilation on PaO2 and PaO2/FiO2 Ratio in Morbidly Obese Patients Undergoing Bariatric Surgery
The purpose of this study is to determine if the application of Boussignac continuous positive airway pressure (CPAP) immediately after extubation improves PaO2 and PaO2/FiO2 ratio in morbidly obese patients undergoing gastric…
- Trial name
- NCT02297828
- Testing
- Boussignac CPAP, Venturi face mask
- Where
- Portugal
- Volunteers
- 24 people
- Sponsor
- Centro Hospitalar do Porto
Emergence From Anesthesia, Mechanical Ventilation
Controlled Ventilation During Anesthetic Emergence
Absolutely - for a ClinicalTrials.gov-style Brief Summary, I'd keep it simple and patient-friendly like your example: The goal of this clinical trial is to learn whether maintaining controlled mechanical ventilation during…
- Trial name
- NCT07853547
- Testing
- Controlled/Full-Support Mechanical Ventilation During Emergence
- Where
- Saudi Arabia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz Medical City
Airway Extubation
Diaphragmatic and Pulmonary US for Extubation Success Prediction
The primary objective is to assess whether the fraction of diaphragmatic shortening in combination with the presence / absence of alveolar-interstitial syndrome evaluated through chest ultrasound may predict successful extubation…
- Trial name
- NCT02799056
- Testing
- Thoracic ultrasound
- Where
- Mexico
- Volunteers
- 82 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Intubation Complication, PreTerm Birth
NIPPV Versus Bi-level Nasal Continuous Positive Airway Pressure Following Extubation
Mechanical ventilation is important in the care of preterm infants with respiratory failure, but may be associated with lung injury. Efforts are needed to avoid or minimize the use of mechanical ventilation.
- Trial name
- NCT02842190
- Testing
- NIPPV
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Airway Extubation
Extubation Advisor: Initial Implementation and Evaluation of a Novel Extubation Clinical Decision Support Tool
Expeditious, safe extubation is vitally important in the care of Intensive Care Unit (ICU) patients, as prolonged mechanical ventilation harms patients and failed extubation (i.e.
- Trial name
- NCT04708509
- Testing
- Extubation Advisor
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- Ottawa Hospital Research Institute
Endotracheal Extubation, Infant, Premature
Comparison of NIV-NAVA vs. N-CPAP After Extubation in Preterm Infants Study
This study is a randomized controlled study to compare if a a non-invasive neurally adjusted ventilatory assist (NIV-NAVA) is better than nasal continuous positive airway pressure (N-CPAP) after extubation in infants' < 30 weeks…
- Trial name
- NCT02590757
- Testing
- NIV-NAVA, N-CPAP
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Seoul National University Hospital
Sedation, Airway Extubation
Inhaled Sedation in Critically Ill Patients
The proposal of this study is to compare inhaled sedation with isoflurane administered via the Sedaconda ACD-S system with intravenous sedation with propofol.
- Trial name
- IS-CRITIC (NCT07000526)
- Testing
- Isoflurane, Propofol
- Where
- 22 sites in Spain
- Volunteers
- 620 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Artificial Airway Management, Obesity &Amp; Overweight
3D-Printed Artificial Airway Fixation Device for Obese Patients
This study is looking for a better way to secure breathing tubes for obese patients who need them. For patients with obesity, a short neck and extra tissue can make it difficult to keep a breathing tube in the correct position.
- Trial name
- NCT07349433
- Testing
- 3D-Printed Personalized Artificial Airway Fixation Device, Conventional Fixation Methods
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Tang-Du Hospital
Respiratory Distress Syndrome, Preterm Infant
Nasal High Frequency Oscillation Ventilation(NHFOV) for Respiratory Distress Syndrome
In very preterm infants with severe respiratory distress syndrome(RDS), invasive ventilation(IV) , besides nasal continuous positive airway pressure (NCPAP) and early/selective pulmonary surfactant administration, is one key…
- Trial name
- NHFOV (NCT03140891)
- Testing
- NHFOV, NCPAP
- Where
- China
- Volunteers
- 206 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Respiratory Insufficiency of Prematurity
Level of Continuous Positive Airway Pressure (CPAP) in Preterm Infants After Extubation (L-CPAP Study)
Despite widely used of nasal CPAP in preterm infants, uncertainties regarding aspects of its application remain. Clinical indications vary greatly between institutions, especially when combined with varieties of systems, devices…
- Trial name
- L-CPAP (NCT00636324)
- Testing
- Nasal CPAP, level 7 to 9 cmH2O, Nasal CPAP, level 4 to 6 cmH2O
- Volunteers
- 23 people
- Sponsor
- Hamilton Health Sciences Corporation
Intubated Infants Were Intend to Extubation Using Noninvasive Ventilation Strategies
A Trial Comparing Noninvasive Ventilation Strategies in Preterm Infants Following Extubation
Respiratory distress syndrome (RDS) is the main cause of respiratory failure in preterm neonates, its incidence varying from 80% to 25% depending on gestational age.When optimal prenatal care is provided, the best approach to…
- Trial name
- NCT03181958
- Testing
- NHFOV, NCPAP, NIPPV
- Where
- China
- Volunteers
- 1,493 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Mechanical Ventilator Weaning, Acute Brain Injury
Brain-injured Patients Extubation Readiness Study
The BIPER study is a stepped wedge cluster randomised clinical trial aiming to decrease extubation failure in critically-ill brain-injured patients with residual impaired consciousness using a simple clinical score.
- Conditions
- Mechanical Ventilator Weaning, Acute Brain Injury, Altered Level of Consciousness, Mechanical Ventilation
- Trial name
- Biper (NCT04080440)
- Testing
- Extubation readiness clinical score, Usual Care
- Where
- 21 sites in France
- Volunteers
- 660 people
- Sponsor
- University Hospital, Clermont-Ferrand