Clinical trials: Airway Response
Airway Response, Lung Transplant Recipients
Bronchial Response to Exercise After Double Lung Transplantation
This study aims to investigate the airway response to exercise and its association with breathlessness in double lung transplant recipients by comparing responses during 5-minute and 15-minute exercise durations.
- Conditions
- Airway Response, Lung Transplant Recipients, Lung Transplant, Challenge Test
- Trial name
- NCT07035743
- Testing
- Exercise
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Healthy Controls
Response of Airway Cells to 20,000 EU of Endotoxin in Normal Adults
The purpose of this study is to determine the range of neutrophil response (influx of PMNs to the airways as determined in sputum) after inhalation of CCRE (20,000 EU).
- Trial name
- NCT00838851
- Testing
- Clinical Center Reference Endotoxin (CCRE)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Coughing Responses at Tracheal Extubation
Comparison of the Effects of Oxycodone Versus Fentanyl on Airway Reflex to Tracheal Extubation and Postoperative Pain
This study was performed to compare the effects of oxycodone and fentanyl on airway and hemodynamic responses and postoperative pain during recovery period in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT03204045
- Testing
- fentanyl, Oxycodone, control
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Yeungnam University College of Medicine
Myalgia, Apnea, Obstructive Sleep
Temporomandibular Disorder (TMD) Pain in Response to Jaw Advancement in People With TMD and Obstructive Sleep Apnea
The purpose of this study is to characterize the course of temporomandibular disorder (TMD) pain in adults with TMD and obstructive sleep apnea (OSA), all of whom are being treated with mandibular advancement splint (MAS)…
- Trial name
- NCT02685202
- Testing
- Mandibular advancement splint
- Volunteers
- 9 people
- Sponsor
- University of North Carolina, Chapel Hill
Airway Responses, Hemodynamic
Attenuation of Airway and Cardiovascular Responses to Extubation in Chronic Smokers
The aim of this blind comparative study was to compare the effects of dexmedetomidine, fentanyl and their combination on airway reflexes and hemodynamic responses to tracheal extubation in Adult chronic male smoking patients…
- Trial name
- NCT04659642
- Testing
- Dexmedetomidine Injection [Precedex], Fentanyl Citrate Injection, dexmedetomidine and fentanyl
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- National Cancer Institute, Egypt
Asthma, Cough
Bronchodilating and Bronchoprotective Effects of Deep Inspirations
The objectives of this research are to compare (i) the bronchodilating and (ii) the bronchoprotective effects of deep inspirations (DIs) in individuals with: (a) asthma, (b) CVA, (c) methacholine-induced cough but normal airway…
- Trial name
- NCT01659476
- Testing
- Methacholine(MCh) Challenge Testing
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Queen's University
Pulmonary Disease, Chronic Obstructive
Evaluation With CT Scan of Possible Changes in Airways After Treatment With Daxas® in Severe Chronic Obstructive Pulmonary Disease Patients
In this study the possible changes in airway geometry and function induced by 6 month oral treatment with Daxas® (roflumilast) will be evaluated.
- Trial name
- NCT01480661
- Testing
- Roflumilast, Functional Respiratory Imaging
- Where
- 2 sites in Belgium
- Volunteers
- 41 people
- Sponsor
- FLUIDDA nv
Tonsillitis
Investigation of Clinical Spectrum, Bacterial Pathogens and Immune Response in Acute Pharyngotonsillitis
Acute pharyngotonsillitis is one of the most common infections encountered by pediatricians. Most children with acute pharyngotonsillitis have symptoms that can be attributed to viral infection.
- Trial name
- NCT00926198
- Where
- 3 sites in Germany
- Volunteers
- 4,500 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Airway Stress Response
Dexmedetomidine vs Labetalol for Airway Stress in Hypertensive Craniotomy Patients
This randomized trial compares dexmedetomidine and labetalol in controlling airway and hemodynamic stress during extubation in hypertensive patients undergoing craniotomy.
- Trial name
- NCT07034898
- Testing
- Dexmedetomidine, Labetalol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Open Craniotomy
Comparison of Dexmedetomidin and Remifentanil for the Effect on Airway Reflex and Hemodynamic Response During Emergence in Patients Undergoing Craniotomy
During recovery from general anesthesia the stimuli of endotracheal tube lead to the coughing, hypertension, tachycardia, which can cause a serious complication.
- Trial name
- NCT01365923
- Testing
- remifentanil, dexmedetomidine with remifentanil
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Yonsei University
Volunteers, Flu Vaccine
Impact of FLU Vaccination on Nasal Resident Memory Immune Responses and Peripheral Respiratory-tropic Memory Immune Responses
Mucosal sites, such as respiratory mucosa, are the primary entry points entry points for pathogens. However, clinical evaluation of vaccines against respiratory respiratory pathogens is currently based primarily on analysis of…
- Trial name
- MUCOVAC_2 (NCT06824779)
- Testing
- Flu Vaccine, Biological samples
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Asthma
Study of Dose-response to Bronchodilator and Dose-finding in Child 2.5 to 6 Years - Study Golden
In older children and adults, bronchodilator (BD) dose-effect relationship is part of the characteristics of asthma disease. There are no data on BD dose-response relationship in wheezy preschool children whose disease…
- Trial name
- DORESI (NCT01470755)
- Testing
- salbutamol, Salbutamol - dose2, Salbutamol -dose3
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Airway Response
Optimal Dose of Alfentanil for Removal of Supreme Laryngeal Mask Airway During Emergence From Desflurane Anaesthesia
This study aims to determine the optimal dose of alfentanil in suppressing the airway reflexes during supreme LMA removal in anaesthetized adult.
- Trial name
- NCT01371968
- Testing
- alfentanil
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Allergic Asthma, Allergy to Cats
Airway Immune Response to Allergens (Use Lay Language Here)
Most asthma is allergic in origin. The purpose of this study is to better understand the airway immune response to inhaled allergens in order to identify factors that promote asthma.
- Conditions
- Allergic Asthma, Allergy to Cats, Allergy to Dust Mites, Allergic Rhinitis
- Trial name
- NCT04619017
- Testing
- Segmental allergen challenge
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- JOSALYN CHO
Anesthesia, Deep Sedation
Comparison of Two Electroencephalograms (EEG) Monitors in Patients Undergoing General Anesthesia
Hypothesis: There is a statistically measurable correlation between qNOX and rough clinical signs of insufficient anti-nociception such as movements during Laryngeal Mask Airway (LMA) insertion, skin Incision, LMA removal.
- Trial name
- NCT02928172
- Testing
- qCON-qNOX, BIS
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cedars-Sinai Medical Center
Allergic Airway Disease
Broccoli Sprout Extract Effects on Allergic Inflammation in the Nose
Allergic airway disease is a term used to describe conditions such as allergic rhinitis and asthma. Among other causative agents, air pollutants and diesel exhaust in particular, have been shown to create and also worsen existing…
- Trial name
- NCT00882115
- Testing
- Broccoli sprout extract (BSE)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Healthy Control
Genetic Susceptibility TO Ozone-induced Airway Inflammation in Humans
The principal purpose of this study is to identify hyper-responsive, responsive and non-responsive groups of healthy human subjects based on their airway neutrophilic response to ozone exposure, and to perform micro-array…
- Trial name
- GARBOZ (NCT00840528)
- Testing
- ozone
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Administration Site Reaction
Airway Responses During Desflurane Anesthesia Via a Laryngeal Mask Airway: Effects of Fentanyl Pretreatment
The investigators plan to test the hypothesis that pretreatment with fentanyl prior to induction of anesthesia would result in reduce the incidence of movements and airway responses to desflurane in patients breathing…
- Trial name
- NCT01277861
- Testing
- Fentanyl
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Texas Southwestern Medical Center
Hypertension on Emergence
Proseal Laryngeal Mask Airway or Endotracheal Tube for Emergence From Neuroanesthesia
Extubation and emergence from anesthesia lead to systemic and cerebral hemodynamic changes that can cause cerebral edema and hemorrhage.
- Trial name
- NCT01718470
- Testing
- Endotracheal tube, LMA
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Ricard Valero
Respiratory Complication
Optimal Effect-site Concentration of Remifentanil for Inhibiting Response to Laryngeal Mask Airway (LMA) Removal
This study was designed to determine the optimal dose of remifentanil that can prevent the complications associated with the removal of LMA without delaying emergence.
- Trial name
- NCT01915108
- Testing
- Remifentanil
- Volunteers
- 128 people
- Sponsor
- Sangjin Park