Clinical trials: Airway Secretion Clearance
Bronchial Secretion Retention
The Efficacy of Breathing Exercise With BreatheMAX Device on Airway Secretion Clearance and Lung Function
The efficacy of breathing exercise with oscillated inspiratory loading and oscillated positive expiratory pressure for airway secretion clearance and lung function in intubated patients, both with and without mechanical…
- Trial name
- BMACPF (NCT02553200)
- Testing
- BreatheMAX (OPEP), BreatheMAX (OIS and OPEP), BreatheMAX (unload and non-oscillated)
- Where
- Thailand
- Volunteers
- 28 people
- Sponsor
- Khon Kaen University
Ventilation Therapy; Complications, Airway Clearance Impairment
In-line Mechanical Insufflation-Exsufflation in the Management of Ventilated Patients
Catheter suction (CS), the standard method for airway secretion management during mechanical ventilation, is invasive and has significant hemodynamic and traumatic side effects.
- Trial name
- NCT05365620
- Testing
- Mechanical In-Line Inexsufflation, catheter suction
- Volunteers
- 120 people
- Sponsor
- Alyn Pediatric & Adolescent Rehabilitation Hospital
Respiratory; Complications, Therapy, Bronchiectasis
ELTGOL and Bronchiectasis. Respiratory Therapy
The ELTGOL technique improves mucociliary clearance in adult patients with bronchiectasis. Primary objective: -To evaluate the efficacy of ELTGOL in stable state patients with bronchiectasis compared to placebo.
- Trial name
- ELTGOLBQ (NCT01578681)
- Testing
- Low Expiration Open glottis inferolateral (ELTGOL), Stretching
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Airway Clearance Impairment
Outcome Comparisons of Vibratory Airway Clearance Devices
This pilot study aims to compare the ability of a higher oscillatory index device versus a lower oscillatory index device on airway secretion clearance and other clinically significant outcomes.
- Trial name
- NCT05873504
- Testing
- High Oscillatory Index Device, Low Oscillatory Index Device
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Rush University Medical Center
Respiratory Insufficiency
Airway Clearance Using Non-Invasive Oscillating Device
This study aims to examine the tolerance, feasibility, and physiological effects in airway clearance by using a novel non-invasive oscillating transducer device (NIOD, FrequencerTM) in critically ill children.
- Trial name
- NCT03821389
- Testing
- NIOD Frequencer
- Volunteers
- 20 people
- Sponsor
- St. Justine's Hospital
Lung Disease
The Effectiveness of BreatheMAX Breathing Device on Secretion Clearance
The purpose of this study is to determined effects of BreatheMAX on secretion clearance.
- Trial name
- ESMOSC (NCT01090804)
- Testing
- BreatheMAX breathing device
- Where
- Thailand
- Volunteers
- 14 people
- Sponsor
- Khon Kaen University
Spinal Cord Injury Cervical
Randomized Controlled Study on T-PEP Versus IPV Method for Lower Respiratory Airways Clearance in Tetraplegic Tracheotomized Spinal Cord Injured Patients
In tetraplegic patients with complete cervical spinal cord injury, respiratory complications are very frequent, especially in the sub-acute phase: the lungs often become obstructed due to the accumulation of secretions and the…
- Trial name
- T-PEP (NCT04142814)
- Testing
- T-PEP, IPV
- Where
- Italy
- Sponsor
- Montecatone Rehabilitation Institute S.p.A.
Atelectasis, Mechanical Ventilation
Bronchoscopic Airway Clearance for Improving Lung Aeration in Mechanically Ventilated Patients With Atelectasis
The goal of this clinical trial is to learn whether bedside flexible bronchoscopy-guided airway clearance can improve lung aeration in adult patients who are receiving invasive mechanical ventilation and have atelectasis with a…
- Trial name
- NCT07594379
- Testing
- Flexible Bronchoscopy-Guided Airway Clearance, Usual Airway Care
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Southeast University, China
Airway Secretion Clearance
Evaluation of High-Frequency Chest Wall Oscillation
To compare the outcomes of patients treated with the Vest and conventional chest physiotherapy to determine if the Vest provides equivalent therapy
- Trial name
- NCT00717873
- Testing
- Airway clearance Device
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Hill-Rom
Cystic Fibrosis
Airway Secretion Clearance in Cystic Fibrosis
The purpose of this study is to compare the effect of three airway secretion clearance techniques (chest physical therapy, flutter device and high frequency chest wall oscillation) on decline in pulmonary function over a three…
- Trial name
- NCT00839644
- Testing
- High frequency chest wall oscillation, Oscillatory Positive Expiratory Pressure, PD&P: Postural drainage and percussion
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- University of Colorado, Denver
Intubation Complication, Stroke, Ischemic
Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning
Adults who are unconscious or severely ill and need a breathing tube connected to a ventilator are at high risk of developing a lung infection (pneumonia) within the first few days in the intensive care unit.
- Conditions
- Intubation Complication, Stroke, Ischemic, Stroke Hemorrhagic, Head Trauma
- Trial name
- PIRAMIDES (NCT06113939)
- Testing
- airway clearance, subglottic secretion aspiration, Ceftriaxone 2 grams daily
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital San Carlos, Madrid
Acquired Brain Injury, Comparative Effectiveness Research
Efficacy of EFA in Acquired Brain Injury
Acquired brain injury (ABI) is one of the biggest cause of death and disability in the world. Patients with ABI often have difficulties with swallow and breath.
- Conditions
- Acquired Brain Injury, Comparative Effectiveness Research, Lung Diseases, Obstructive
- Trial name
- NCT05993364
- Testing
- Free Aspire with Expiratory Flow Accelerator (EFA) technology, In-Exufflator Machine, Traditional respiratory treatment
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Smoking, Smoking Cessation
Smoking Cessation on the Human Airway: Mucus Secretion, Inflammatory and Proteomic Profile in Nose and miRNAs in Blood
Smoking cessation improves health conditions with reduction of the risk factors for cardiovascular and respiratory disease, as functional capacity and quality of life.
- Trial name
- NCT02136550
- Testing
- Smoking cessation
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cystic Fibrosis, Pulmonary
Airway Clearance System (K031876) Phase IV Device Efficacy
Phase IV interventional study of adults (18 to 55) having a diagnosis of cystic fibrosis (mild, moderate or severe). The study is completely voluntary and is designed to measure participants use and the effectiveness of the…
- Trial name
- NCT03437811
- Testing
- Electro Flo Percussor, Model 5000
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mack Biotech, Corp.
Broncho-degenerative Disease, Chronic Obstructive Airway Disease
Evaluation of the Safety of the Medical Device Simeox®
The purpose of this study is to determine whether the medical device "simeox" is safe in the treatment of respiratory diseases, in comparison with traditional physiotherapy.
- Conditions
- Broncho-degenerative Disease, Chronic Obstructive Airway Disease, Cystic Fibrosis, Idiopathic Bronchiectasis
- Trial name
- SIMETOL (NCT02061852)
- Testing
- Simeox, Physiotherapy
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Physio-Assist