Clinical trials: Alcohol, Drinking
Alcohol Use Disorder, PTSD
Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress Disorder
The project will examine whether a computerized neuroscience-based cognitive training program can improve cognitive functioning and recovery outcomes among Veterans with Alcohol Use Disorder and co-occurring PTSD.
- Conditions
- Alcohol Use Disorder, PTSD, Cognitive Dysfunction
- Trial name
- NCT02929979
- Testing
- Cognitive Training
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Alcohol Abuse
Optimisation of Functional MRI-based Neurofeedback for Alcohol Use Disorders
Participants will undergo a single session of functional magnetic resonance imaging (fMRI)-based neurofeedback (approximately 1 hour).
- Trial name
- NCT02406456
- Testing
- Neurofeedback
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cardiff University
Alcoholism
Levetiracetam XR in Very Heavy Drinkers
The primary objectives of this study are to assess the efficacy of levetiracetam XR in increasing the percentage of subjects with no heavy drinking days and in reducing the weekly percentage of heavy drinking days in subjects…
- Trial name
- NCIG 002 (NCT00970814)
- Testing
- BBCET, Levetiracetam XR, Sugar Pill
- Where
- 5 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Depression, Anxiety
Remotely Delivered Programs Targeting COVID-19 Stress-Related Depression and Substance Use
This 3-arm study compares the effectiveness of an (1) 8-week mindfulness-based intervention, MBCT-R (Mindfulness-Based Cognitive Therapy for Resilience During COVID-19)+CHA MindWell vs.
- Conditions
- Depression, Anxiety, Substance Use, Stress, Psychological
- Trial name
- NCT04595084
- Testing
- Mindfulness Based Cognitive Therapy for Resilience During COVID-19 plus CHAMindWell, Internet Cognitive Behavioral Therapy plus CHAMindWell, CHAMindWell
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Alcohol Drinking
Measuring the Neuroimmune Response to Alcohol
This study uses positron emission tomography imaging of the 18-kDa translocator protein to measure the brain's immune response to alcohol.
- Trial name
- NCT04251221
- Testing
- Oral Alcohol Challenge
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Use Disorder, Alcoholism
Effect of Social Isolation on the Role of Pavlovian Mechanisms for Control Over Alcohol Use
During the first funding period (1st FP) we investigated the impact of acute and chronic stress (Trier Social Stress Test, TSST) on Pavlovian-to-instrumental transfer (PIT).
- Conditions
- Alcohol Use Disorder, Alcoholism, Stress Reaction, Ostracism
- Trial name
- ReCoDe (NCT06256952)
- Testing
- PIT paradigm, social exclusion (Cyberball task), Saliva samples
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Alcohol Use Disorder, Insomnia
Mobile App Intervention for Sleep Problems and Alcohol Use Among Veterans
The goal of this clinical trial is to test the preliminary efficacy of a brief mobile app targeting insomnia symptoms among veterans.
- Trial name
- NCT06487793
- Testing
- Enhanced Insomnia Coach, Sleep hygiene comparator
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Alcohol Use Disorder
Nalmefene, Baclofen and Impulsivity in Subjects With Alcohol Use Disorder and Healthy Control Subjects
Impulsivity is a central feature of addiction. Nalmefen is an authorized treatment for alcohol addiction. Baclofen has empathically been advocated to have some efficacy in this indication.
- Trial name
- NCT03034408
- Testing
- Nalmefene, Baclofen
- Where
- Switzerland
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Prof. Daniele Zullino
Sexual Behavior, Alcohol Drinking
Young Adult Education on Alcohol & Health
The goal of this clinical trial is to test the effectiveness of our brief online program when compared to those who don't complete the program at all.
- Conditions
- Sexual Behavior, Alcohol Drinking, Condomless Sex
- Trial name
- NCT05620849
- Testing
- Online program
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Washington
Alcohol Drinking, Cannabis Use
Developing and Testing an Online Intervention for Alcohol and Cannabis Misuse and Healthy Relationship Skills Among Young Adult Couples
The goal of this clinical trial is to develop and test a brief online intervention to reduce alcohol and cannabis misuse and improve healthy relationship skills among young adult couples.
- Conditions
- Alcohol Drinking, Cannabis Use, Couples
- Trial name
- NCT06422299
- Testing
- Online, couples-based intervention
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Washington
Drinking, Alcohol, Drinking Behavior
Inhibitory Control Smartphone App
The proposed study will address a critical knowledge gap: there are no evidence-based smartphone apps for reducing young adult drinking.
- Trial name
- NCT04243759
- Testing
- Control App Version, Standard App Version, Experimental, Feedback App Version
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alcohol Use, Alcohol Drinking
Young Adult Naturalistic Alcohol Study (YANAS) Using Smartphone Technology in a Simulated Laboratory Environment
It is important to explore use of technology to reduce drinking. The purpose of this research study is to compare different types of mobile technology for their effects on alcohol drinking and ratings of usability among young…
- Conditions
- Alcohol Use, Alcohol Drinking, Drinking Behavior
- Trial name
- NCT02841735
- Testing
- Smartphone breathalyzer device/app use, BAC estimator app use, Text messaging procedure
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alcohol Drinking, Alcohol; Harmful Use
Reducing Hazardous Alcohol Use in Social Networks Using Targeted Intervention: 21 Rising
The primary goal of this study is to determine whether change in alcohol use among college students can be transmitted through social network ties to other members in the network.
- Trial name
- NCT04147520
- Testing
- Brief Motivational Interview
- Where
- United States
- Volunteers
- 1,475 people, healthy volunteers welcome
- Sponsor
- Brown University