Clinical trials: Alcohol Addiction
Addiction, Substance Use Disorder
Group Version of CRAFT Compared to Self-Directed CRAFT Delivery and Non-intervention: a Three-armed RCT
The aim of this study is to determine whether a group format Community Reinforcement and Family Training (CRAFT) and Self-Directed CRAFT Delivery are more effective than non-intervention in terms of Concerned Significant Others…
- Conditions
- Addiction, Substance Use Disorder, Alcohol Use Disorder, Substance- Related Disorder
- Trial name
- NCT02510508
- Testing
- Group CRAFT, Self-Directed CRAFT Delivery, Non-intervention
- Where
- 6 sites in Netherlands
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- IrisZorg
Insomnia, Alcohol Use Disorder
CBT-I on Alcohol Treatment Outcomes Among Veterans
Project SAVE aims to examine the feasibility, acceptability, and initial efficacy of a CBT-I supplement to alcohol treatment of Veterans.
- Trial name
- Project SAVE (NCT03806491)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene, Alcohol Use Disorder Treatment as Usual
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Substance Use
Integration of (iSBIRT) for Teen Drug Use Into a Pediatric Network
The Goal of this project is to integrate a previously-tested internet-facilitated Screening, Brief Intervention, and Referral to Treatment (iSBIRT) system for adolescent substance use into a large network of primary care offices…
- Trial name
- NCT01454206
- Testing
- iSBIRT
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Alcohol Abuse
Family Intervention for Teen Drinking in the ER
The investigators propose a randomized controlled trial with five aims: 1. To investigate the engagement potential and effectiveness of a family-centered intervention (MDFT) and Family Motivational Interviewing Intervention…
- Trial name
- NCT01229748
- Testing
- Standard Care, Multidimensional Family Therapy, Family Motivational Interviewing Intervention
- Where
- 3 sites in United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Miami
Alcohol Use Disorder, Post Traumatic Stress Disorder
Imaging Traumatic Stress and Alcohol Use Disorder With [18F]Bavarostat
The overall objective of this study it to use Positron Emission Tomography (PET) brain imaging and a radiotracer that measures the epigenetic marker Histone Deacetylase 6 (HDAC6) to examine HDAC6 expression in people with…
- Trial name
- NCT06371404
- Testing
- Bavarostat
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol Abuse
A Community-Based Strategy for Preventing Underage Drinking
This project evaluates a combination of policy and social influence interventions to reduce adolescent alcohol use and its sequelae.
- Trial name
- NCT02448134
- Testing
- Youth Access
- Where
- United States
- Volunteers
- 7,379 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Alcohol; Use, Problem, Stress
A Behavioral Activation Intervention Administered in a College Freshman Orientation Course
The transition from high school to college is a developmentally sensitive period that is high risk for escalations in alcohol use.
- Conditions
- Alcohol; Use, Problem, Stress, Binge Eating, Depression
- Trial name
- NCT04038190
- Testing
- behavioral activation
- Where
- United States
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Alcohol Dependance
Cortical rTMS as a Tool to Change Brain Reactivity to Alcohol Cues
The goal of this investigation is to determine if, in heavy alcohol users, a single session of transcranial magnetic brain stimulation (TMS) over a brain region involved in craving (medial prefrontal cortex) and a brain region…
- Trial name
- ARC4 (NCT02939313)
- Testing
- medial prefrontal cortex, dorsolateral prefrontal cortex
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alcohol Use Disorder, Posttraumatic Stress Disorder (PTSD)
Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use Disorders
The purpose of this study is to evaluate whether the combination of prazosin and naltrexone will decrease alcohol cravings and drinking in individuals who have problems with alcohol and have used alcohol at risky levels compare…
- Trial name
- PaN (NCT02322047)
- Testing
- Prazosin, Naltrexone
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Alcohol Abuse
Personal Values and Mandated Students
This study aims to examine the efficacy of an enhanced alcohol intervention among individuals who are mandated to complete an alcohol education activity as part of a university sanction.
- Trial name
- NCT03247647
- Testing
- Enhanced Intervention, Standard Intervention
- Where
- 2 sites in United States
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Brown University
Alcohol Use Disorder
Phase 1b Study of DCR-AUD in Healthy Volunteers
The goal of this clinical trial is to test the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of of repeat doses of DCR-AUD in adult healthy volunteers who are social drinkers.
- Trial name
- NCT05845398
- Testing
- DCR-AUD
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Alcohol Use Disorder
Learning and Relapse Risk in Alcohol Dependence (FP2)
The investigators will examine clinical alterations in learning and automated approach behaviour and their neurobiological correlates in alcohol-dependent patients and healthy social drinkers and assess whether they are affected…
- Trial name
- LeAD_FP2 (NCT02615977)
- Testing
- Zooming Joystick Task
- Where
- 3 sites in Germany
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Alcohol Use Disorder
Considering Healthier Drinking Options in Collaborative Care
The purpose of this study is to evaluate the effectiveness of a collaborative care intervention for evidence based management of alcohol use disorders in primary care settings within the Veterans Administration Puget Sound Health…
- Trial name
- CHOICE (NCT01400581)
- Testing
- Collaborative Care Intervention
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Alcohol Use Disorder
In Hospital IM Naltrexone: A Pilot Study
This is a study in-hospital administration of injectable naltrexone vs. oral naltrexone. This is a pilot study to assess provider's and patient's acceptability to be randomized to oral vs.
- Trial name
- IM-NTX (NCT05087771)
- Testing
- injectable naltrexone, oral naltrexone
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Alcohol Abuse
Effects of Motivational Interviewing in Prison
Motivational Interviewing (MI) is a communication style demonstrated to decrease drug and alcohol use. A five session MI intervention (BSF) was implemented in the Swedish correctional system.
- Trial name
- NCT01184612
- Testing
- Motivational Interviewing; MI
- Where
- Sweden
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Alcohol Addiction, Mouth Diseases
Testing Interventions to Reduce Alcohol Consumption Among Outpatients in a Dental Setting
The investigators wish to investigate the feasibility of using a web based drinking app (www.drinksmeter.com) to reduce alcohol consumption among patients attending an outpatient clinic in a dental setting.
- Trial name
- NCT02374905
- Testing
- Drinksmeter, Brief Advice of Alcohol Use
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
High Intensity Use of Urgent and Emergency Care, Emergency Medicine
High Intensity Use of Urgent and Emergency Care: A Mixed-Methods Study
This study aims to understand the health and social care needs and experiences of adults who frequently use urgent and emergency care services in Dorset.
- Conditions
- High Intensity Use of Urgent and Emergency Care, Emergency Medicine, Health Inequalities, Mental Health
- Trial name
- NCT07630012
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Alcoholism
Project 4: Acute Effects of Alcohol on Learning and Habitization in Healthy Young Adults
This project aims to investigate how dysfunctional learning and habitization are affected by acute alcohol exposure, and whether individual differences in such alcohol effects can predict later development of Alcohol Use…
- Trial name
- LeAD_P4 (NCT01858818)
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Alcohol Abuse, Alcohol Drinking
Substance Use Risk Education (SURE) Project
This project is designed to compare college drinking interventions on outcomes and cost-effectiveness. We plan to recruit 700 students with residence hall alcohol violations to participate in a randomized study to evaluate 3…
- Trial name
- NCT00289965
- Testing
- Counselor-administered Brief Motivational Intervention (BMI), Alcohol 101 Plus (interactive CD-ROM), AlcoholEdu (Internet-based tutorial)
- Where
- United States
- Volunteers
- 703 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Alcohol Abuse, Drug Abuse
A Web App for Patients With Alcohol and Drug Use Problems in Primary Care
The objective of this pilot study is to evaluate the feasibility and technical merit of a web application for patients in primary care called Check-up and Choices (CC).
- Trial name
- NCT01830114
- Testing
- Web app
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Behavior Therapy Associates, LLP