Clinical trials: Alcohol Disorders
Alcohol Abuse, Drug Use
The Weaving Healthy Families Program
Alcohol and other drug (AOD) abuse and violence in families are co-occurring risk factors that drive health disparities and mortality among Native Americans (NA), making the long-term goal of this research is to promote health…
- Conditions
- Alcohol Abuse, Drug Use, Violence, Domestic, Child Abuse
- Trial name
- NCT03924167
- Testing
- Weaving Healthy Families Program
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tulane University
Folate Deficiency
Food and Alcohol Behavior Study: Meaningful Enhancement
This study will determine how folate supplementation affects both serum and red blood cell folate status in females ages 18 -24 years old.
- Trial name
- FAB:ME (NCT04095052)
- Testing
- Methyl Folate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Substance Use (Drugs, Alcohol), Tobacco Use
The ICEC Cluster Trial: Integrated Community Engagement Collaborative for Youth Substance Use Prevention in Rural America
This study will evaluate whether the Integrated Community Engagement (ICE) Collaborative can help prevent alcohol, tobacco, and other drug use among youth living in rural communities.
- Conditions
- Substance Use (Drugs, Alcohol), Tobacco Use, Adolescent Substance Use
- Trial name
- NCT07843576
- Testing
- Integrated Community Engagement Collaborative, School-Based Data Collection and Reporting without Network Coordinator Support
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- West Virginia University
HIV Infections, HIV/AIDS
Evaluation of a Home-based Community Health Worker Program in Rural Eastern Cape, South Africa
The purpose of this early Phase 2 comparison trial is to evaluate the impact of community health worker (CHW) home visitors on pregnant women and their children in a rural setting in the rural Eastern Cape of South Africa.
- Conditions
- HIV Infections, HIV/AIDS, Depression, Depressive Symptoms
- Trial name
- NCT03517878
- Testing
- Comprehensive CHW Program
- Where
- 2 sites in South Africa
- Volunteers
- 1,490 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Depression, Anxiety, Alcohol Abuse
Cognitive-Behavioral Therapy for Young Adult Lesbian, Gay and Bisexual: Transdiagnostic Minority Stress Approach
Background: LGB people experience a large number of anxiety and mood disorders, and risk behaviors than heterosexual (Marshall et al., 2011).
- Conditions
- Depression, Anxiety, Alcohol Abuse, Sexual Compulsivity, Unsafe Sex
- Trial name
- NCT03980873
- Testing
- ESTEEM (Effective Sikills to Empower Effective Men)
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Alcoholic Hepatitis
Protective Immune Mechanisms in Alcoholic Hepatitis
The purpose of this study is to investigate the production, effects and interactions of the hepato-protective cytokine interleukine (IL)-22 in patients with alcoholic hepatitis.
- Trial name
- AHIL (NCT01918462)
- Where
- Denmark
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Alcohol Use Disorder, Depression
The Network Study: Soldiers Connecting for Work and Health
This study will examine the efficacy of an internet-based brief intervention designed to reduce risky behavior in Soldiers as they transition from Active Duty into the civilian workforce as a Veteran.
- Trial name
- NCT04463225
- Testing
- Internet-Delivered Brief Intervention
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Cornell University
Alcohol Drinking, Alcohol Intoxication
Efficacy of the Dietary Food Supplement ALCOFILTRUM in Alleviating Alcohol Hangover Symptoms
The aim of this open-label, randomized, crossover, comparative pilot study is to assess efficacy and safety of the dietary food supplement ALCOFILTRUM in healthy volunteers who consume alcohol.
- Trial name
- NCT05757089
- Testing
- ALCOFILTRUM
- Where
- Belarus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- AVVA Pharmaceuticals Ltd.
HIV Infections, Alcohol Use Disorder
An Effectiveness Trial of the PrEP for WINGS Study
(Effectiveness Aim 1) To test the comparative effectiveness of PreP for WINGS versus PrEP alone on primary outcomes of increasing PrEP initiation measured by self-report/medical records, recent adherence and longer-term adherence…
- Conditions
- HIV Infections, Alcohol Use Disorder, Violence, Gender-Based
- Trial name
- PFW (NCT06853314)
- Testing
- PrEP for WINGS, PrEP Decision Aid
- Where
- United States
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Columbia University
Substance Use
Unidos Against ATOD Use Intervention Trial
Adolescent alcohol tobacco and drug (ATOD) use is a major public health concern, with rates for Latino middle school youth higher than other ethnic groups.
- Trial name
- TWC (NCT03642106)
- Testing
- Unidos Se Puede
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Alcohol Use, Alcohol Consumption
FLOW: Influence of the Menstrual Cycle on Alcohol Use in Women
The FLOW study aims to assess the association between menstrual cycle phases and alcohol consumption in women from the general population.
- Conditions
- Alcohol Use, Alcohol Consumption, Menstrual Cycle, Women's Health
- Trial name
- FLOW (NCT07910643)
- Where
- France
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cardiovascular Disease, Type 2 Diabetes
Moderate Alcohol Consumption, Risk of Cardiovascular Disease and Type 2 Diabetes: Influence of Alcohol Oxidation
Moderate alcohol consumption is associated with a decreased risk of cardiovascular disease and type 2 diabetes. The association of alcohol consumption with cardiovascular disease is mediated by a functional polymorphism of…
- Trial name
- NCT00285909
- Testing
- Alcohol: 25 gday (white wine)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- TNO
Intoxication Alcohol
Stop-Service to Obviously-Impaired Patrons
The Responsible Retailing Forum ("RRF") seeks to develop a new intervention, Stop Service to Obviously- Impaired Patrons ("S-STOP"), to reduce the incidence and harm associated with overservice of alcohol.
- Trial name
- SSTOP (NCT03608787)
- Testing
- S-STOP
- Where
- United States
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- RRF Field Services LLC
Dental Plaque
Efficacy of Two Commercially Available Chlorhexidine Mouthrinses Non-alcohol Base
The purpose of this study was to compare the antiplaque efficacy of a 0,12% chlorhexidine and 0,05% cetyl-pyridinium chloride mouth rinse (Perio-aid®) with a 0,2% chlorhexidine non-alcohol base mouth rinse (Corsodyl Care®).
- Trial name
- NCT01580943
- Testing
- Chlorhexidine
- Where
- Portugal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Substance Dependence
EtOH Interaction Study
This study will investigate the possible effects of alcohol in combination with GSK598809 on the central nervous system in 20 healthy male and female volunteers, between 18 and 65 years of age.
- Trial name
- NCT00887367
- Testing
- GSK598809, Ethanol
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Binge Drinking, HIV
Better Than Study: Targeting Heavy Alcohol Use With Naltrexone Among Men Who Have Sex With Men (MSM)
This is a double-blind, placebo-controlled trial of 120 binge-drinking MSM to 12 weeks of naltrexone 50mg, to be taken in anticipation of heavy drinking.
- Trial name
- SayWhen (NCT02330419)
- Testing
- Naltrexone, Medical Management (MM) counseling for alcohol use:, Urinalysis for novel alcohol biochemical markers:
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Obesity
Weight Gain in First-year University Students
The transition to university from secondary school comes with many changes to living arrangements, dietary and alcohol intake, physical activity, and stress.
- Trial name
- NCT05856734
- Testing
- Weight and body composition change, Change in dietary intake, Change in physical activity
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Alcohol Intoxication
Neurosteroids and Acute Alcohol Intoxication in Humans
1. The major aims are to assess: (1) the relationship of basal and alcohol-induced neurosteroid and GABA levels to the degree of acute alcohol intoxication in healthy male and female volunteers; and (2) the effect of acute…
- Trial name
- NCT00608686
- Testing
- Pregnenolone
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Use Disorder
Study of Mechanisms of Emotion Regulation in Alcohol-abstinent Patients
Background: Difficulties in assigning and identifying emotional states, or to regulate the emotional costs are recognized as one of the major factors of relapse.
- Trial name
- REAL (NCT02881983)
- Testing
- the presentation of pictures (static stimuli) or videos (dynamic stimuli)
- Where
- 2 sites in France
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Healthy Adult Male and Female Volunteers
Safety and PK Study of BICX104 With or Without Bupropion Compared to Vivitrol
Naltrexone (NTX), an opioid receptor antagonist, has a longstanding history of safe and effective use for the treatment of addictive disorders.
- Trial name
- NCT07269873
- Testing
- BICX104 naltrexone implantable pellet, Bupropion 150 mg XL, Naltrexone (depot)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BioCorRx Pharmaceuticals Inc