Clinical trials: Alcohol Misuse Treatment
Liver Diseases, Alcoholic, Alcohol Use Disorder
Alcohol Misuse Treatment to Patients Newly Diagnosed With Alcohol-related Liver Disease: a Randomized Controlled Trial
To evaluate the efficacy of systematically offering newly diagnosed ALD patients to AUD treatment, in the hepatology clinic, on alcohol abstinence after 6 months.
- Conditions
- Liver Diseases, Alcoholic, Alcohol Use Disorder, Treatment Adherence, Alcoholism
- Trial name
- NCT06493773
- Testing
- Offer of specialized alcohol use disorder treatment in the hepatology clinic
- Where
- Denmark
- Volunteers
- 221 people
- Sponsor
- Zealand University Hospital
Alcohol Use Disorder
Internet-delivered Therapy for Alcohol Misuse: Investigating Patient Preference for Self-guided or Guided Treatment
Internet-delivered cognitive behaviour therapy (ICBT) shows promise as a method of treating alcohol misuse. In this form of treatment, patients complete online lessons over several weeks that assist patients in developing skills…
- Trial name
- NCT04611854
- Testing
- Guidance, ICBT for alcohol misuse
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Regina
Psychosis, Alcohol Use Disorder
Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis
Psychotic disorders impact 4.6 people per 1000 globally, with approximately 1.5 million Canadians affected. The age of onset for psychotic disorders often begin during the critical years of youth and early adulthood, resulting in…
- Conditions
- Psychosis, Alcohol Use Disorder, Cannabis Use Disorder
- Trial name
- NCT07056894
- Testing
- Action-Based Cognitive Remediation
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Alcohol Misuse
Brief Alcohol Treatment for Women Veterans in Primary Care
The goal of this study is to develop and test a brief behavioral treatment for women Veterans with alcohol use in primary care. The study involves a development phase, an open trial phase, and a pilot randomized controlled trial.
- Trial name
- NCT07414589
- Testing
- Brief, Integrated Intervention for Women Veterans with Unhealthy Alcohol Use in Primary Care, Primary care usual care
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Syracuse VA Medical Center
Alcohol Misuse, Hypertension
Telehealth Treatment of Veterans With Alcohol Misuse at Risk for Cardiovascular Disease
The primary objective of this project is to refine a cognitive-behavioral intervention for comorbid alcohol misuse and modifiable CVD risk with diverse stakeholder input, so that the intervention can be deployed within existing…
- Conditions
- Alcohol Misuse, Hypertension, Elevated Cardiovascular Risk
- Trial name
- ACME-TM (NCT04838457)
- Testing
- Alcohol and CVD Management and Engagement through Telehealth and mHealth (ACME-TM)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Alcohol Dependency
Alcohol Screening, Brief Intervention, and Referral to Treatment in a Military Treatment Facility
An alcohol Screening, Brief Intervention and Referral to Treatment (SBIRT) approach will be adapted for use in a large military hospital setting, and then pilot tested in a military emergency department (ED) to assess its…
- Trial name
- NCT02228967
- Testing
- SBIRT
- Where
- United States
- Volunteers
- 791 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Alcohol Misuse
Internet-delivered Therapy for Alcohol Misuse: Factorial Trial of Assessment and Guidance
Internet-delivered cognitive behaviour therapy (ICBT) shows considerable promise as a convenient treatment for alcohol misuse. ICBT may differ in whether the user works alone (self-guided) or along with an individual who guides…
- Trial name
- NCT03984786
- Testing
- Assessment Interview, Guidance, ICBT for alcohol misuse
- Where
- Canada
- Volunteers
- 312 people
- Sponsor
- University of Regina
Substance Use Disorder (SUD), Opioid Use Disorder
Disease Intervention Specialist (DIS) for SUD
This prospective observational study evaluates three Disease Intervention Specialist service models designed to proactively identify and support adults at risk for substance use disorder.
- Conditions
- Substance Use Disorder (SUD), Opioid Use Disorder, Alcohol Use Disorder (AUD), Drug Use
- Trial name
- DIS-SUD (NCT07875361)
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Ohio State University
Alcohol Use Disorder, Supplementation
Administration of Fiber as a Dietary Supplement to Improve the Management of Alcohol Withdrawal
The goal of this clinical trial is to demonstrate that a fiber-enriched diet (with a high proportion of inulin and pectin) combined with standard care can reduce intestinal permeability in patients with alcohol use disorder (AUD)…
- Conditions
- Alcohol Use Disorder, Supplementation, Intestinal Permeability
- Trial name
- FIB-ALC (NCT07371286)
- Testing
- Administration of fibers as a dietary supplement
- Volunteers
- 138 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alcohol Use, Unspecified
Behavioral Economic Treatment to Enhance Rural (BETTER) Living
The purpose of this trial is to get feedback to help develop programs delivered by phone and text messages to improve wellness and health behaviors.
- Trial name
- NCT05235971
- Testing
- Episodic Future thinking, Volitional choice, Monitoring only
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Michigan
Posttraumatic Stress Disorder, Alcohol Use Disorders
Brief Restructuring Intervention Following Trauma Exposure
The broad aim of this study is to develop and test a brief intervention that can be implemented in the immediate weeks following sexual assault to decrease likelihood of developing posttraumatic stress disorder (PTSD) or alcohol…
- Trial name
- BRITE (NCT02808468)
- Testing
- Brief Cognitive Therapy
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Washington
Intervention Engagement and Retention
Improving Attendance in Community Wise
Rates of alcohol and substance misuse (ASM) in low-income, predominantly African American communities are similar to the general population.
- Trial name
- NCT05934591
- Testing
- Community Wise
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Alcohol Misuse
Development and Evaluation of a Theory and Evidence-based Intervention to Reduce Hazardous Alcohol Consumption Among Treatment Seeking Smokers
This study will evaluate the implementation of a fully automated, direct-to-patient digital alcohol intervention embedded within the STOP Program's patient portal.
- Trial name
- NCT07228923
- Testing
- Brief alcohol intervention
- Where
- Canada
- Volunteers
- 77 people
- Sponsor
- Centre for Addiction and Mental Health
Alcohol Misuse
Adaptive Actions and Alcohol Use Outcomes During Internet-delivered Cognitive Behaviour Therapy
This observational study investigates an Internet-delivered Cognitive Behaviour Therapy (ICBT) intervention for alcohol misuse, called the Alcohol Change Course Enhanced (ACCE).
- Trial name
- NCT07021053
- Testing
- Alcohol Change Course Enhanced
- Where
- Canada
- Volunteers
- 165 people
- Sponsor
- University of Regina
Alcohol Use
Project Guard: Reducing Alcohol Misuse/Abuse in the National Guard
The overall goal for the study is to test the efficacy of a smartphone app which includes an alcohol brief intervention (SP-BI) versus an Enhanced Usual Care (EUC) condition for National Guard members in the State of Ohio who…
- Trial name
- NCT02860442
- Testing
- Smartphone brief intervention (SP-BI), Enhanced Usual Care (EUC)
- Where
- 2 sites in United States
- Volunteers
- 850 people
- Sponsor
- Keming Gao
Substance Use
Cultural Adaptation of Drug Treatment for DJJ Youth
This project aims to improve the understanding of the impact of Ethnic and Racial Discrimination (ERD) on adolescent alcohol and other drug use (AOD) within the Black Justice-Involved Youth (JIY) population.
- Trial name
- CAST (NCT06003725)
- Testing
- Culturally Adapted Adolescent Substance Use Treatment
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Alcohol Use Disorder
The Connect Trial: Connecting Hospital Patients to Alcohol Care
The main objective of this pilot study is to assess feasibility of conducting a definitive RCT with concealed allocation, blinded outcome assessment and a 1:1 parallel group design of A) an invitation to meet an AUD therapist for…
- Trial name
- NCT07482150
- Testing
- AUD treatment sessions with an outreach alcohol therapist at the hospital, Guidance and leaflet on AUD treatment facilities outside the hospital
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Zealand University Hospital
Alcohol Misuse Treatment, Alcohol Misuse
Designing and Evaluating Multi-level Implementation Strategies to Address Alcohol Use Within Oncology Care
To assess the potential effects of our multi-level implementation strategies for increasing SBIRT for alcohol use among cancer patients and to refine our methods, the investigators are conducting a pilot-trial with 4 clinics and…
- Trial name
- NCT07752576
- Testing
- Multi-level Implementation Strategy
- Volunteers
- 265 people
- Sponsor
- University of Pennsylvania
Co-Occurring Alcohol and Drug Misuse
Contingency Management for the Treatment of Co-Occurring Alcohol and Drug Misuse
Contingency management (CM) is a type of treatment used in the substance abuse field. Patients' behaviors are rewarded for adherence to a treatment plan.
- Trial name
- NCT02222389
- Testing
- CM for Alcohol, CM for drugs, CM for both substances
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Washington State University
Alcohol Use Disorder
Testing the Efficacy of an Online Integrated Treatment for Comorbid Alcohol Misuse and Emotional Problems
Considering the high comorbidity between alcohol use disorders and emotional problems, there is currently a need for accessible, integrated treatments designed to target both disorders simultaneously.
- Trial name
- NCT03406039
- Testing
- Integrated Online CBT and MI
- Where
- Canada
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- University of Manitoba