Clinical trials: Alcohol Related Disorders
Nonsuicidal Self Injury, Alcohol Abuse
Technology Enhanced Adolescent Mental Health (TEAM)
Adolescent nonsuicidal self-injury (NSSI) and alcohol misuse, alone and especially in combination, portend significant functional impairment in adulthood (e.g., relationship dysfunction, depression, suicidality).
- Conditions
- Nonsuicidal Self Injury, Alcohol Abuse, Vagus Nerve Stimulation
- Trial name
- TEAM (NCT05343039)
- Testing
- Non-invasive Transcutaneous Nerve Stimulation (tVNS), No Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Alcohol Consumption, Alcohol Abuse/Dependence
Social Facilitation of Alcohol Effects and Alcohol Misuse in Young Adults
The purpose of this study is to understand social contexts and alcohol use. We hope to learn how being around peers affects alcohol consumption in young adults.
- Trial name
- PALS (NCT06627803)
- Testing
- Alcohol (Oral)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Alcohol Abuse
Brief Online Study Abroad Alcohol Intervention
This study involves a randomized controlled trial that builds upon a successful pilot intervention study to address problematic and dangerous drinking among young adult college students studying abroad in foreign environments.
- Trial name
- NCT03928067
- Testing
- PNF + SAF
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- RAND
Alcohol Drinking, Intoxication Alcohol
Alcohol-Containing Products' Effect on Breathalyzer Results in Healthy Adults Without Acute Intoxication
This study is a prospective, controlled study in healthy volunteers all of whom are residents, medical students, faculty physicians, or emergency department nursing and ancillary staff.
- Trial name
- NCT04878653
- Testing
- BACtrack S80 Breathalyzer
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- CHRISTUS Health
Severe Alcoholic Hepatitis, Chronic Liver Disease and Cirrhosis
Invasive Fungal Infections in Severe Alcohol-associated Hepatitis
Chronic alcohol consumption is associated with intestinal bacterial dysbiosis, yet little is known about the role of intestinal fungi, or mycobiota in liver disease.
- Trial name
- NCT04103840
- Testing
- Testing stool mycobiota
- Where
- India
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Alcohol Dependence, Veterans
Long-Acting Injectable Naltrexone Treatment of Alcohol Dependence in Primary Care vs. in Specialized Chemical Dependence Treatment: A Pilot Trial
The goal of the proposed project is to improve the primary care treatment of veterans with alcohol dependence. Alcohol dependence is a common behavioral health problem among veterans treated in VA primary care clinics.
- Trial name
- NCT00461890
- Testing
- Injectable Naltrexone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Alcohol Drinking, Cannabis Use
Cannabis' Impact on Alcohol Consumption
This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which…
- Conditions
- Alcohol Drinking, Cannabis Use, Cannabis, Alcohol Use Disorder
- Trial name
- NCT05389930
- Testing
- THC-dominant cannabis, CBD-dominant cannabis, Alcohol
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Brown University
Alcohol Use Disorder, Alcohol Use, Unspecified
Drinking, Acetate, and Stress
The purpose of this study is to learn how drinking alcohol affects how people experience stress and how that is affected by the body's chemistry.
- Conditions
- Alcohol Use Disorder, Alcohol Use, Unspecified, Heavy Drinker, Alcohol Use Disorder, Moderate, in Sustained Remission
- Trial name
- NCT06584448
- Testing
- Deuterium Metabolic Imaging with deuterated acetate tracer
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity, Alcohol Dependence
Norepinephrine Transporter Imaging in Addiction Disorders
In this study we propose to study 24 unmedicated abstinent alcohol dependent patients, 24 obese individuals and 24 individually matched healthy control subjects and determine Norepinephrine Transporter (NET) expression in vivo…
- Trial name
- NCT01719458
- Testing
- (S,S)-[11C]MRB
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Substance Abuse, Risk Reduction
First Years Away From Home: Letting Go and Staying Connected
Alcohol abuse is the leading cause of death and serious injury among college students, and students also experience significant harms from other types of substance misuse and risk behaviors.
- Conditions
- Substance Abuse, Risk Reduction, RIsky Sexual Behavior
- Trial name
- FYAH:LGSC (NCT03227809)
- Testing
- Handbook condition, Handbook plus condition
- Where
- United States
- Volunteers
- 910 people, healthy volunteers welcome
- Sponsor
- Washington State University
Heavy Episodic Drinking
Understanding the Associations Between Romantic Relationship Conflict, Psychophysiological Responding and Alcohol Misuse Among Emerging Adults
Emerging Adults (EA) engage in heavy episodic drinking (HED) at a greater quantity and frequency than any other time in their lives, which may lead to significant short- and long-term consequences.
- Trial name
- NCT06976528
- Testing
- Alcohol administration
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- New York University
Alcohol Use Disorder
Scale-up of Prevention and Management of Alcohol Use Disorders and Comorbid Depression in Latin America
A quasi-experimental study will compare primary health care-based prevention and management of alcohol use disorder, operationalized by heavy drinking, in three intervention cities from Colombia, Mexico and Peru with three…
- Trial name
- SCALA (NCT03524599)
- Testing
- Intervention municipality
- Where
- Colombia
- Volunteers
- 690 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Addiction, Alcohol, Urinary Tract Disease
Does Homebrewing Beer Affect Urinary Tract Symptoms and Bladder Cancer
In this study, investigators aim to reveal the harmful effects of increasing consumption of homemade beer in recent years on the urinary tract.
- Trial name
- NCT05134675
- Testing
- Homemade beer
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Alcoholism
Ketamine/Placebo Family History Positive Study
The proposed study is the first to explore the contribution of brain glutamate systems, a major target of ethanol in the brain, to the vulnerability to develop alcoholism.
- Trial name
- NCT00588952
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Yale University
PTSD, Alcohol Use Disorder
Peer Delivered, Emotion Regulation-Focused Mental Health Prevention Training for Fire Fighter Trainees
The goal of this clinical trial is to determine if a peer-delivered emotion regulation training (Brief-Unified Protocol) workshop is effective for preventing posttraumatic stress and other psychological health symptoms in…
- Conditions
- PTSD, Alcohol Use Disorder, Depression, Anxiety
- Trial name
- PEER UP (NCT06290778)
- Testing
- Brief Unified Protocol, Psychoeducation
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Alcoholism, Healthy
Serotonin in Alcoholism
This study uses positron emission tomography (PET) scanning to study how serotonin works in alcoholics. Serotonin is a chemical that allows brain cells to communicate.
- Trial name
- NCT00011752
- Testing
- FCWAY
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Dependence
Binge Drinking And Addiction : Case-Control Study in Hospital
Case Control Study : Objective: Frequent Binge drinking during 18-25 years is a risk factor of alcohol addiction in adulthood (25-40 years) Hypothesis: 25% of frequent binge drinking, OR = 2, power 80%, alpha risk : 5% 126 Cases…
- Trial name
- BACH (NCT03204214)
- Where
- France
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Marie-Pierre TAVOLACCI
Behavior, Drinking, Alcohol Drinking
Effectiveness of a PMT Intervention to Reduce Alcohol in Young Adults
This study will examine the effectiveness of a 7-minute informational video using the threat and coping components of the Protection Motivation Theory (PMT) reduces alcohol intention and behaviour among young Canadian adults.
- Conditions
- Behavior, Drinking, Alcohol Drinking, Colorectal Cancer Control and Prevention, Healthy Volunteers
- Trial name
- NCT06615648
- Testing
- PMT, Non-contact Control
- Where
- Canada
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Binge Drinking
The Brain, the Bug, and the Binge: the Interplay Between Binge Drinking, Gut Microbiota, and Brain Functioning
Adolescence and youth are periods of significant maturational changes which seems to involve greater susceptibility to disruptive events in the brain such as binge drinking (BD).
- Trial name
- NCT05946083
- Testing
- Inulin Intervention, Maltodextrin Intervention
- Where
- Portugal
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Minho
Heavy Drinking, Alcohol Abuse
Effects of Acute Exercise on Various Parameters in Individuals With Alcohol Use Disorders
The purpose of this research is to examine the effects of exercise of different intensities on psychological, physiological, biochemical, physiological and alcohol-related parameters in individuals with alcohol use disorders…
- Conditions
- Heavy Drinking, Alcohol Abuse, Alcohol Dependence, Alcohol Use Disorder
- Trial name
- NCT02664727
- Testing
- The effects of acute exercise in heavy drinkers, The effects of acute exercise in alcoholic patients
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Thessaly