Clinical trials: Alcohol-induced Disorders
Alcohol Use Disorder
Social Cognition and Executive Functions in Alcohol Use Disorders - Transverse Study
Over the past few years, researchers and clinicians have stressed the major role of executive and social cognition impairments in the development and the maintenance of Alcohol Use Disorders (AUD).
- Trial name
- COSEFEX-T (NCT04647422)
- Testing
- Analysis of executive functioning and of social cognition processes
- Where
- France
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Substance-Related Disorders, Underage Drinking
Testing a Brief Substance Misuse Preventative Intervention for Parents/Guardians of 5th-7th Grade Students
The current study aims to test the efficacy of a family communication-based, novel, adaptable, and resource-efficient substance misuse preventive intervention for parents/guardians of pre/early adolescents (grades 5-7).
- Conditions
- Substance-Related Disorders, Underage Drinking, Drug Use
- Trial name
- NCT03925220
- Testing
- The SUPPER Project, Improving nutrition and physical activity among youth
- Where
- United States
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Tufts University
Fear, Stress
Traits Associated With Early Life Stress Among Treatment-Seeking Alcoholics
Background: Researchers want to see if people with alcohol dependence have more trouble learning to feel calm, or learn to fear things more easily, than non-alcoholics and to study how early life stress (ELS) affects these…
- Conditions
- Fear, Stress, Alcohol Dependence
- Trial name
- NCT02181608
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcoholic Intoxication
Computer-Assisted Self-Administration of Ethanol
This study will test the reliability of a procedure for self-administering ethanol (alcohol) intravenously (through a vein), using a computer-assisted method.
- Trial name
- NCT00713492
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Ride Sharing, Alcohol Drinking
The Rise of Ride Sharing Companies and Trends in Impaired Driving Accidents
This will be a retrospective study with data collected from the trauma registry. We plan to complete the data collection and analysis by 12/31/2020. Data on ride sharing will be obtained from the Uber and Lyft websites.
- Conditions
- Ride Sharing, Alcohol Drinking, Alcohol Intoxication, Drug Use
- Trial name
- NCT04564599
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Methodist Health System
HIV/AIDS, Alcohol Abuse
An Economic and Relationship-strengthening Intervention for HIV-affected Couples Who Drink Alcohol in Malawi
A couples-based alcohol-reduction and economic and relationship-strengthening intervention for HIV-affected couples in Malawi.
- Trial name
- NCT04906616
- Testing
- Mlambe
- Where
- Malawi
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Alcohol Abuse, Alcohol Drinking
Substance Use Risk Education (SURE) Project
This project is designed to compare college drinking interventions on outcomes and cost-effectiveness. We plan to recruit 700 students with residence hall alcohol violations to participate in a randomized study to evaluate 3…
- Trial name
- NCT00289965
- Testing
- Counselor-administered Brief Motivational Intervention (BMI), Alcohol 101 Plus (interactive CD-ROM), AlcoholEdu (Internet-based tutorial)
- Where
- United States
- Volunteers
- 703 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Alcohol-Related Disorders, Alcohol Use Disorders
Tailored Mobile Text Messaging to Reduce Problem Drinking
This study is designed to develop and test a tailored adaptive text messaging/short message service (SMS) intervention for individuals interested in stopping or reducing their alcohol consumption; and test and compare it to…
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- NCT01885312
- Testing
- Adaptive Tailored Intervention, Consequence-based Intervention, Tailored, not adaptive, based Intervention
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Alcohol Consumption
Role of Dopamine in Response to Alcohol
This study will examine the role of the brain chemical dopamine in people's response to alcohol consumption. Dopamine is thought to influence whether people have a strong or weak response to alcohol and how pleasurable that…
- Trial name
- NCT00050219
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Use Disorder, Early Trauma Complications
Neurobiological Responses in Alcoholism and Early Trauma
Alcohol use disorder (AUD) accompanied by early trauma presents clinical challenges, including elevated rates of comorbid emotional symptoms and relapse.
- Trial name
- NCT04128228
- Testing
- 8-week outpatient treatment
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Yale University
Substance Use Disorder, Delinquency
Early Intervention for Minors in Possession of Alcohol/Drugs: A Feasibility Study
The purpose of this study is to evaluate two brief, sustainable interventions for a sample of 280 adolescents charged with an initial drug-related offense: Motivational Enhancement Therapy (MET) intervention for youth and the…
- Trial name
- MAST1 (NCT01616212)
- Testing
- Motivational Enhancement Therapy /Adol and PW for parents, Motivational Enhancement Therapy for adolescents, Drug Education for adolescents, Parenting Wisely for parents
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Alexithymia, Alcohol Use Disorder
Impact of Art Therapy on Alexithymia in People With Alcohol Use Disorder
Art therapy support combined with standard care for people with an alcohol use disorder coming to a day hospital for withdrawal could be beneficial compared to standard care alone because it would improve the alexithymia of these…
- Trial name
- ALEXART (NCT04206930)
- Testing
- Art Therapy
- Where
- France
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Cannabis Use, Alcohol Use Disorder
VRT as a Biomarker of Cerebellar Dysfunction in Chronic Cannabis Use
Chronic cannabis consumption has been associated with poor psychosocial functioning that could be associated to cerebellar dysfunction.
- Conditions
- Cannabis Use, Alcohol Use Disorder, Healthy
- Trial name
- NCT03662737
- Testing
- Visuomotor adaptation task
- Where
- Spain
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Alcohol Abuse
Mentored Research on Improving Alcohol Brief Interventions in Medical Settings
The NIAAA estimates that 16% (40 million) of adults in the US are drinking at unsafe levels. More than 50% of alcohol health consequences occur in risky, non-dependent drinkers.
- Trial name
- NCT02978027
- Testing
- Brief Advice, NIAAA Clinician's Guide, Motivational Interviewing (MI)
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Alcohol Dependence, Alcohol Abuse
Community Reinforcement and Family Training (CRAFT) for Treatment-resistant Individuals With Alcohol Use Disorders
The present study examines the efficacy of the Community Reinforcement and Family Training (CRAFT) for Concerned Significant Others (CSOs) of individuals with alcohol use disorders (AUDs) using a randomized waiting list (WL)…
- Trial name
- CRAFT (NCT02112396)
- Testing
- Community Reinforcement and Family Training
- Where
- Germany
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Luebeck
Alcohol Use Disorder
A Pilot Study of Non-invasive Brain Stimulation to Boost the Efficacy of Psychotherapy in a Community Sample of People Who Drink Alcohol
The goal of this small (n=75) proof-of-concept randomized clinical trial is to test the effects of transcranial alternating current stimulation (tACS) during motivational interviewing (MI) sessions with participants who drink at…
- Trial name
- tACS-MI (NCT04770025)
- Testing
- High-density transcranial alternating current stimulation, Motivational interviewing
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The Mind Research Network
Alcohol Abuse, Liver Disease
Biomarkers for the Detection of Heavy Alcohol Use in Patients With and Without Liver Disease
The investigators will test the validity of biomarkers for the detection of heavy alcohol use in patients with and without liver disease.
- Trial name
- NCT02873663
- Testing
- Plasma and head hair collection
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Alcohol Use Disorder
A First in Human Study of CMND-100 in Healthy and Alcohol Use Disorder (AUD) Subjects
The primary objective of this study is to find the tolerable dose and characterize the safety and pharmacokinetics/ pharmacodynamics (PK/PD) of single and repeated dose of CMND-100 in Healthy Volunteers (HV) and Subjects with…
- Trial name
- NCT05913752
- Testing
- CMND-100
- Where
- 4 sites in United States, Israel
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Clearmind Medicine Inc.
PTSD, Alcohol Use Disorder
Peer Delivered, Emotion Regulation-Focused Mental Health Prevention Training for Fire Fighter Trainees
The goal of this clinical trial is to determine if a peer-delivered emotion regulation training (Brief-Unified Protocol) workshop is effective for preventing posttraumatic stress and other psychological health symptoms in…
- Conditions
- PTSD, Alcohol Use Disorder, Depression, Anxiety
- Trial name
- PEER UP (NCT06290778)
- Testing
- Brief Unified Protocol, Psychoeducation
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Opioid-use Disorder, Opioid Abuse, in Remission
Mindfulness-Based Relapse Prevention for Opioid and Alcohol Use Disorders
A randomized controlled trial will examine mindfulness-based relapse prevention (MBRP) program outcomes for 240 individuals who have completed treatment for opioid or alcohol use disorders.
- Conditions
- Opioid-use Disorder, Opioid Abuse, in Remission, Alcohol Use Disorder, Alcohol Use Disorder, in Remission
- Trial name
- MBRP (NCT04278352)
- Testing
- Mindfulness Based Relapse Prevention
- Where
- 3 sites in United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Clemson University