Clinical trials: Algorithm
Multiple Sclerosis
Genes and Environment in Multiple Sclerosis
The purpose of the research study is to identify the genetic, environmental and immune profiles that may increase a person's risk of developing multiple sclerosis (MS).
- Trial name
- GEMS (NCT01353547)
- Where
- 5 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Anxiety Disorders, Major Depressive Disorder
Acquisition and Analysis of Relationships Between Longitudinal Emotional Signals Produced by an Artificial Intelligence Algorithm and Self-questionnaires Used in the Psychiatric Follow-up of Patients With Mood and/or Anxiety Disorders: a Real-Environment Study.
The worldwide prevalence of anxiety and depression increased massively during the pandemic, with a 25% rise in the number of patients suffering from psychological distress.
- Trial name
- EMOACQ-1 (NCT05988840)
- Testing
- Acquisition and analysis of relationships between Longitudinal Emotional Signals produced by a software and Self-questionnaires.
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Emobot
Focus is on Healthy Subjects
Validation of Pulse Wave Doppler Demodulation Algorithm for the Continuous, Non-invasive Measurement of Blood Flow Velocity
The investigators hypothesize that performance of fast-Fourier transformation on the raw Doppler signals obtained from ascending aortic blood flow will recreate the pulse wave Doppler trace visualized on modern echocardiography…
- Trial name
- NCT01750125
- Testing
- measure ascending aortic blood flow with pulse wave Doppler
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Weight-Estimation
Can Habitus Adapted Length Based Body Weight Estimation be Improved by Adding Further Parameters?
The purpose of this prospective single center study is to investigate if the accuracy of length based body weight estimation by the already investigated algorithm (CLAWAR) can be improved by adding another parameter.
- Trial name
- Including MUC (NCT02930928)
- Testing
- Accuracy of weight estimation
- Where
- Switzerland
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Steatohepatitis, Nonalcoholic
The COherence of Scatter Identification and Exclusion Algorithm Study
Non-alcoholic fatty liver disease (NAFLD) is currently the most common liver condition worldwide; approximately 55% of the world population will have NAFLD by 2040.
- Trial name
- COSIE (NCT06975579)
- Testing
- Ultrasound image processing
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Institute of Cancer Research, United Kingdom
Covid19
Evaluation of a COVID-19 Pneumonia CXR AI Detection Algorithm
This study investigates the diagnostic performance of an AI algorithm in the detection of COVID-19 pneumonia on chest radiographs.
- Trial name
- NCT04561024
- Testing
- AI model
- Where
- Hong Kong
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Ensemble Group Holdings, LLC
Point-of-care Ultrasound
AI for Gastric POCUS ( Point-of-care Ultrasound)
The goal of this observational study is to train and test an AI (Artificial Intelligence)-based program to assist anesthesiologists in the interpretation of stomach ultrasound images and differentiate a "full" from an "empty"…
- Trial name
- POCUS (NCT07580456)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Infertility, Polycystic Ovary Syndrome
A New Algorithm to Predict Ovarian Age
To collect data of clinical, biochemical and 3D-ultrasonographic parameters of a population of fertile women aged 18-55 in order to design a new algorithm able to predict ovarian age and to evaluate the reliability of a…
- Conditions
- Infertility, Polycystic Ovary Syndrome, Premature Ovarian Failure (POF), Ovarian Cysts
- Trial name
- OvAge (NCT02086318)
- Testing
- OvAge assessment
- Where
- Italy
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Obstructive Sleep Apnea Syndrome
Validation of Sleep Monitoring Algorithm Based on Smart Watches
In recent years, wearable devices are booming to enable not only the health monitoring but also the sleep efficiency assessment.
- Trial name
- NCT06696196
- Testing
- smart watches(wearable devices)
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Attention Deficit Hyperactivity Disorder
System for Determining Ideal Drug Doses for ADHD - Stages 1 and 2
The goal of this study is to create a formal, quantitative methodology to determine what is the most beneficial dose of Central Nervous System (CNS) stimulant (Ritalin, methylphenidate) to improve cognitive and behavioral…
- Trial name
- NCT03523663
- Testing
- no intervention. measure eye movement data
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Hypertension
Recording of Physiological Data Via an Optical Sensor At the Fingertip Alongside with Double Auscultatory and Pulse Oximetry to Evaluate the Effectiveness of an Optical Blood Pressure Monitoring (OBPM)
The present study, OBPM_Calfree2024, with N = 85 participants minimum over 1 visit (lasting around 1h), has been designed to collect raw optical data with Aktiia.product-G2C Clinical investigational system together with several…
- Trial name
- NCT06368206
- Testing
- Investigational device Aktiia G2C, Marketed device used as reference for blood pressure monitoring: double auscultation cuff, Marketed device used as comparative device for blood pressure and pulse rate monitoring: Aktiia Bracelet G2
- Where
- Switzerland
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Aktiia SA
Healthy
Decision Algorithm for Vital Sign Assessment in the Outpatient Physical Therapy Setting
Brief Summary The goal of this observational study is to develop consensus-based criteria for when vital sign assessment (VSA) should be performed in outpatient physical therapy settings.
- Trial name
- NCT07258030
- Testing
- E-Delphi
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Youngstown State University
Obstructive Sleep Apnea, Obstructive Sleep Apnea-hypopnea
Updating Deep Learning Algorithms for OSA Monitoring
The objective is to enhance the reliability of the algorithm to match that of Level 1 polysomnography by leveraging the diverse data obtained from Level 1 polysomnography to refine the deep learning algorithm.
- Trial name
- NCT06522815
- Testing
- CART-I plus, Polysomnography
- Where
- South Korea
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Sky Labs
Sepsis, Severe Sepsis
Unsupervised Machine Learning for Clustering of Septic Patients to Determine Optimal Treatment
The focus of this study will be to conduct a prospective, randomized controlled trial (RCT) at Cape Regional Medical Center (CRMC), Oroville Hospital (OH), and UCSF Medical Center (UCSF) in which a fluid treatment-specific…
- Conditions
- Sepsis, Severe Sepsis, Septic Shock
- Trial name
- NCT03752489
- Testing
- Treatment-specific InSight, InSight
- Volunteers
- 51,645 people, healthy volunteers welcome
- Sponsor
- Dascena
Hearing Loss
Hearing Aid Algorithms for Sudden Sounds
This study explores the impact of hearing aid settings for managing sudden sounds on speech comprehension and recall in individuals with hearing loss.
- Trial name
- NCT06340919
- Testing
- Sudden Sound Reduction Setting
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Purdue University
Posterior Chamber Phakic Intraocular Lens, Vault
Study on the Diagnostic Efficacy of ICL Selection and Prediction Depth Model Based on Eye Images
To evaluate the diagnostic efficacy of deep learning network model in implantable collamer lens selection and prediction in a multicenter cross-sectional study
- Conditions
- Posterior Chamber Phakic Intraocular Lens, Vault, Deep Neural Network, Myopia
- Trial name
- NCT06669728
- Testing
- AI diagnostic algorithm
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Algorithm Verification
mCVI Pilot Study: Algorithm Verification
This single center pilot study is to verify the algorithm of mCVI® to accurately capture pulse rate and respiratory rate in 10 healthy subjects in comparison to commercially-available Masimo pulse oximeter devices.
- Trial name
- NCT04297644
- Testing
- There is no intervention
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Intelomed, Inc.
Obstructive Sleep Apnea
Revised Algorithm for Next Generation DeVilbiss Healthcare AutoAdjust Continuous Positive Airway Pressure (CPAP)
The purpose of this protocol is to improve the current FDA-approved continuous positive pressure auto-titration algorithm, including treatment precision, residual disease detection characteristics and phenotyping with the…
- Trial name
- NCT01797705
- Testing
- DeVilbiss AutoAdjust CPAP with revised algorithm
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- DeVilbiss Healthcare LLC
Pregnancy
Clinical Data Collection for Obstetric Ultrasound Algorithms
The goal of this clinical trial is to Collect ultrasound data from pregnant and non-pregnant individuals presenting to multiple study sites.
- Trial name
- MOBUS (NCT06742229)
- Testing
- Research Ultrasound scan
- Where
- 3 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Caption Health, Inc.
Acute Myocardial Infarction (AMI)
POCT Detection for Blood Concentration of Tirofiban in Acute Myocardial Infarction Based on Azo-POP Probe.
The goal of this observational study is to monitor blood drug concentration during the use of tirofiban, predict the occurrence of intraoperative and postoperative complications related to interventional therapy, and evaluate the…
- Trial name
- NCT06836531
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Ningbo University