Clinical trials: Alignment, open to volunteers
Contraceptive Behavior, Social Norms
Impact of Gender-Transformative Interventions on Contraceptive Use and Reproductive Autonomy in Somalia
Since 2019, the International Rescue Committee (IRC) has led family planning programming in Somalia under the Women's Integrated Sexual Health (WISH) program, funded by the United Kingdom's Foreign, Commonwealth and Development…
- Trial name
- FPIL-SOM (NCT07902700)
- Testing
- Intensive Gender-Transformative Programming, Light-Touch Gender-Transformative Programming, Standard Family Planning Services (WISH-2)
- Where
- Somalia
- Volunteers
- 5,436 people, healthy volunteers welcome
- Sponsor
- Guttmacher Institute
Knee Osteoarthritis (Knee OA)
Intelligent Precision Knee Preservation System for Knee Osteoarthritis
The goal of this clinical trial is to verify whether the "dynamic dual-mode alignment optimization + intelligent precision knee-preserving system" (integrating static/kinematic target alignment, CT-based preoperative…
- Trial name
- NCT07284524
- Testing
- HTO procedure
- Where
- China
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Health Literacy
Health Literacy in Geriatric Patients
Health Literacy is one's ability to understand health information well enough to make informed decisions about their health. Limited health literacy makes it hard for people to understand complex health issues and follow health…
- Trial name
- NCT06971393
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Hamilton Health Sciences Corporation
Mobility Impairment, Clinical Workflow Optimization
Deployment and Evaluation of Humanoid Robotics in Coalition-Aligned Clinical Care Settings
This clinical trial evaluates the deployment of humanoid robotics in coalition-aligned healthcare settings. The study measures biometric performance, ESG compliance, and operational impact across patient care, sanitation, and…
- Conditions
- Mobility Impairment, Clinical Workflow Optimization, Sanitation Protocol Compliance, ESG-linked Healthcare Robotics Deployment
- Trial name
- HEALTH (NCT07214896)
- Testing
- Skin Cell Dip, Stem Cell Dip, Wage Token Distribution
- Where
- 4 sites in United States, Germany and 1 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Unicompartmental Knee Replacement, Osteo Arthritis Knee
RCT: Mako Medial Unicondylar Knee Arthroplasty vs Oxford Unicondylar Knee Arthroplasty
The overall aim of this prospective, randomised, single-blinded, controlled trial is to compare clinical outcomes and accuracy of implant positioning in Mako robotic UKA versus jig-based Oxford UKA with navigation control.
- Conditions
- Unicompartmental Knee Replacement, Osteo Arthritis Knee, Surgery
- Trial name
- NCT04095637
- Testing
- Medial knee arthroplasty
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University College, London
Crowding of Anterior Mandibular Teeth
Efficiency, Efficacy, Periodontal & Occlusal Outcomes for Aligners Versus Fixed Orthodontic Appliances in Crowded Incisor Treatment
The goal of this clinical trial is to compare between fixed labial braces and clear aligners for the straightening of moderately overlapped lower front teeth.
- Trial name
- NCT06731465
- Testing
- Clear aligner therapy, Fixed pre-adjusted edgewise orthodontic appliance
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- University of Sharjah
Sacroiliac Dysfunction
COMBINATION OF LATISSIMUS DORSI AND GLUTEAL STRENGTHENING IN SACROILIAC DYSFUNCTION
The current study will try to answer the following research question: In adults with sacroiliac joint dysfunction, what is the effect of combination LD strengthening exercises with gluteal strengthening exercises compared with…
- Trial name
- NCT07477717
- Testing
- Gluteal strengthening exercise program, Gluteal strengthening combined with LD strengthening exercise program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Office Workers, Spinal Alignment
Rigid Taping's Effects on Posture and Balance in Office Workers
This study looks at whether applying a rigid tape to the upper back can immediately improve posture and balance in people who spend long hours sitting at a desk.
- Conditions
- Office Workers, Spinal Alignment, Balance Assessment
- Trial name
- NCT07815769
- Testing
- Rigid taping
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Arthritis, Arthritis (Knee)
Kinematic Alignment in Total Knee Arthroplasty - a Double-blind Randomised Controlled Trial Between Robotic and Caliper-based Techniques
Knee replacement surgery is a surgery designed to treat severe arthritis of the knee. However, as many as 20% of patients are not satisfied with the results of their surgery.
- Conditions
- Arthritis, Arthritis (Knee), Osteoarthritis, Osteoarthritis Knee Pain
- Trial name
- NCT06709703
- Testing
- Kinematic aligned total knee replacement
- Volunteers
- 200 people
- Sponsor
- Université de Sherbrooke
CIED-related Infections, CIED Implantation
CIED Implantation Technique at Assiut University Heart Hospital in Relation to ESC Guidelines
This prospective observational cohort study will evaluate the extent to which cardiac implantable electronic device (CIED) implantation techniques at Assiut University Heart Hospital (AUHH) align with the evidence-based…
- Trial name
- NCT07210801
- Testing
- CIEDimplantation
- Volunteers
- 200 people
- Sponsor
- Assiut University
Myopia, Refractive Ametropia
Comparison of Two Rotational Alignment Methods for Astigmatism Correction in SMILE Surgery
Small incision lenticule extraction (SMILE) is a commonly used corneal refractive procedure for correcting myopia and myopic astigmatism.
- Trial name
- NCT07696468
- Testing
- Device-assisted cyclotorsion control during SMILE, Manual limbal marking-guided cyclotorsion adjustment during SMILE
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Sleep
Circadian Rhythms and Homeostatic Sleep Drive and Their Effect on Reward and Cognitive Control Systems in Adolescents
Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their…
- Trial name
- CARRS-P1 (NCT05336084)
- Testing
- Ultradian sleep/wake protocol
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Upper Crossed Syndrome, Postural Dysfunction
Effect of a Comprehensive Corrective Exercise Program With and Without Instrument-Assisted Soft Tissue Mobilization on Cervical Range of Motion, Muscle Strength, Disability, and Postural Alignment in Individuals With Upper-Crossed Syndrome
This study is a double-blind, parallel-group randomized controlled trial designed to evaluate the effectiveness of a Comprehensive Corrective Exercise Program (CCEP) with and without Instrument-Assisted Soft Tissue Mobilization…
- Trial name
- NCT07702604
- Testing
- Instrument-Assisted Soft Tissue Mobilization (IASTM) + Comprehensive Corrective Exercise Program (CCEP), Comprehensive Corrective Exercise Program (CCEP)
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Presbyphonia, Deep Cervical Muscles
THE EFFECT OF POSTURAL ALİGNMENT AND DEEP CERVICAL MUSCLE TRAINING ON VOICE FUNCTION IN OLDER ADULTS WITH PRESBYPHONIA
This study examined whether posture exercises and deep neck muscle training can improve voice quality in older adults with presbyphonia, an age-related voice disorder.
- Trial name
- PRESBYPHONIA (NCT07771114)
- Testing
- Neck Stabilization Exercises Group, Control Group
- Volunteers
- 90 people
- Sponsor
- Suleyman Demirel University
Arthritis Foot, Bone Alignment Defaults
Evaluation of the Treatment of Arthritis and the Correction of Bone Alignment Default of the Toes With Lync
The "LYNC" clinical investigation aims to confirm the clinical benefits, performance and safety of the Lync® device when implanted in the toes for the treatment of arthritis and correction of bone misalignments.
- Trial name
- LYNC (NCT06888934)
- Testing
- Intervention with Lync device.
- Where
- 5 sites in France
- Volunteers
- 76 people
- Sponsor
- Novastep
Knee Arthropathy
Influence of Different Prostheses on Postoperative Clinical Function in Total Knee Arthroplasty
Exploring differences in knee function after surgery with different types of prostheses(Cruciate ligament retaining(CR) VS. posterior stabilizing(PS))
- Trial name
- NCT06617819
- Testing
- CR prosthesis, PS prosthesis
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Thoracolumbar Compression Fractures
Short Segment Versus Long Segment Transpedicular Screw Fixation in the Correction and Preservation of AO-Type B Thoracolumbar Fracture Alignment: A Comparative Study
To compare the radiological, clinical and functional outcomes of short-segment versus long-segment transpediclular screw fixation in patients with thoracolumbar fractures AO-type B.
- Trial name
- NCT07777653
- Testing
- Short Segment Versus Long Segment Transpedicular Screw Fixation in the Correction and Preservation of AO-Type B Thoracolumbar Fracture Alignment: A Comparative Study
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Osteo Arthritis of the Knee, Obesity & Overweight
Alignment Techniques in TKA RCT
The purpose of this research study is to compare two different methods used to align the knee during a total knee arthroplasty (TKA): technology-assisted inverse kinematic alignment, and manual-instrumented gap balancing…
- Trial name
- NCT07646158
- Testing
- Technology-assisted inverse kinematic alignment TKA, Manual-instrumented gap balancing alignment TKA
- Volunteers
- 80 people
- Sponsor
- Jacob M. Elkins
Cases Who Received TKA/THA
Knee-Hip-Spine Harmony: The Relationship Between Sagittal Spinal Alignment in Total Hip/Knee Arthroplasty
Concomitant osteoarthritis of hip/knee joint and lumbar spinal degeneration is commonly seen in elderly population. These degeneration changes of spine would change sagittal or coronal alignment and spinal flexibility in varies…
- Trial name
- NCT05685706
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- China Medical University Hospital
Knee Osteoarthritis, Knee Arthropathy
Mechanical Alignment vs Kalipered Kinematic Alignment Total Knee Arthroplasty
Knee replacement surgery can be performed in one of two ways. Traditionally the goal was for the new joint to be in a neutral position with respect to the femur (thigh bone). This is called Mechanical Alignment (MA).
- Trial name
- NCT06617871
- Testing
- Mechanical Alignment (MA), Kinematic Alignment (KA) Interventions:
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Northwestern University