Clinical trials: All Surgery
Fecal Incontinence, Childhood ALL
Management of FI After Surgery of ARM
The posterior sagittal approach to anorectal malformation (ARM) has radically changed the outcome of these patients, improving the preservation of anal sphincters, owing to their anatomical identification.
- Conditions
- Fecal Incontinence, Childhood ALL, Anorectal Malformations
- Trial name
- NCT05621629
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Knee Replacement
Study of an All Polyethylene Tibial Component
This will be a prospective single cohort investigation of the Columbus all polyethylene tibia (Aesculap AG, Tuttlingen, Germany) used in total knee arthroplasty (TKA) surgery.
- Trial name
- NCT02540902
- Testing
- All-polyethylene tibia (Aesculap AG)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Golden Jubilee National Hospital
Surgical Site Infection
Novosyn® CHD vs Polyglactin 910 Suture to Close Wounds After Emergency or Elective Laparotomy or Laparoscopic Surgery
The aim of the study is to elucidate, if the colonization of bacteria is lower on the Novosyn® CHD suture compared to uncoated Polyglactin 910 suture, which will be assessed by the incidence of surgical site infections (SSI: A1…
- Trial name
- POLYNOVO-CHD (NCT05966961)
- Testing
- Novosyn® in emergency or elective laparotomy or laparoscopic surgery, Polyglactin 910 in emergency or elective laparotomy or laparoscopic surgery
- Where
- 4 sites in Italy, Spain
- Volunteers
- 2,998 people
- Sponsor
- Aesculap AG
Primary Osteoarthritis of Knee Nos
All Ligaments Left In Knee Arthroplasty Trial
Compare the clinical and patient reported outcomes of the Vanguard XP Knee System to the Vanguard CR Knee System in patients with antero-medial osteoarthritis of the knee with an intact anterior cruciate ligament.
- Trial name
- ALLIKAT (NCT03302013)
- Testing
- Vanguard XP Bi-cruciate Retaining Knee Replacement System, Vanguard CR Single Cruciate Retaining Knee System
- Where
- 4 sites in United Kingdom
- Volunteers
- 260 people
- Sponsor
- University of Oxford
Ankle Lateral Ligament, Gait Analysis
Gait Pattern Analysis After All Arthroscopic ATFL Repair Surgery
The study will investigate alterations in post-surgical gait patterns among patients who have undergone all arthroscopic repair surgery for the anterior talofibular ligament (ATFL) due to ankle instability.
- Trial name
- NCT06253624
- Testing
- All Arthroscopic ATFL Repair Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Gazi University
All Diseases That Require Gastrointestinal Open Surgery
Subcutaneous Closed-Suction Drainage Affects Surgical Wounds Healing in Lower Gastrointestinal Open Surgery: a Randomized Controlled Study
This is a single-center, randomized controlled trial to evaluate whether subcutaneous closed-suction drainage would decrease the incidence of poor surgical site healing in lower gastrointestinal open surgery.
- Trial name
- NCT05318430
- Testing
- Subcutaneous closed-suction drainage device
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Beijing Friendship Hospital
Clear Cell Renal Cell Carcinoma, Renal Cell Carcinoma (RCC)
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
This phase III trial compares the effect of adding tivozanib to standard therapy pembrolizumab versus pembrolizumab alone for the treatment of patients with high-risk renal cell carcinoma (RCC).
- Conditions
- Clear Cell Renal Cell Carcinoma, Renal Cell Carcinoma (RCC), Stage II Renal Pelvis Cancer AJCC v8, Stage III Renal Pelvis Cancer AJCC v8
- Trial name
- STRIKE (NCT06661720)
- Testing
- Pembrolizumab, Tivozanib, Biospecimen Collection
- Where
- 429 sites in United States
- Volunteers
- 1,040 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Brain Tumor, Central Nervous System Tumors
Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors
RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Giving a chemotherapy drug before surgery may shrink the tumor so that it is no longer present by…
- Conditions
- Brain Tumor, Central Nervous System Tumors, Childhood Germ Cell Tumor
- Trial name
- NCT00047320
- Testing
- carboplatin, etoposide, ifosfamide
- Where
- 106 sites in United States, Australia and 3 more
- Volunteers
- 104 people
- Sponsor
- Children's Oncology Group
Burn Out Syndrome
Level of Burn Out of Surgical Residents Working in All Hospitals of Lahore
The term burnout was coined by psychologist Herbert Freudenberger in 1974 in an article entitled "Staff Burnout" in which he discussed job dissatisfaction precipitated by work-related stress.
- Trial name
- NCT02206139
- Where
- 2 sites in Pakistan
- Volunteers
- 150 people
- Sponsor
- Services Hospital, Lahore
Risk Reduction, Urological Cancer
STRONG for Surgery & Strong for Life - Against All Odds: Intensive Prehabilitation for Risk Reduction in Cancer Surgery
Despite knowledge about the effect of preventive measures in lifestyle, smoking,nutrition, alcohol and physical activity (SNAP), there is a lack of systematic assessment of the overall lifestyle of the patient before surgery and…
- Conditions
- Risk Reduction, Urological Cancer, Surgery, Life Style
- Trial name
- STRONG-CS (NCT04088968)
- Testing
- Prehabilitation
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Bispebjerg Hospital
Analgesic, Enhanced Recovery After Surgery
Efficacy and Safety of Acetaminophen in Postoperative Pain Management of Infants
Pain will bring early and long-term adverse reactions to infants. The investigators need to pay attention to whether there is pain in infants after surgery.
- Conditions
- Analgesic, Enhanced Recovery After Surgery, Postoperative Pain, Infant ALL
- Trial name
- NCT05564819
- Testing
- Acetaminophen, Sterilized water
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Nanjing Children's Hospital
Blood Loss, Surgical
Observational Cohort Study of TachoSil (TC-018-IN)
The purpose of this study is to collect information, after exposure to TachoSil ®, of all thromboembolic events, immunological events and drug interactions leading to thromboembolic events or major bleeding.
- Trial name
- NCT00285623
- Testing
- Fibrinogen (human) + thrombin (human) (TachoSil)
- Where
- Denmark
- Volunteers
- 3,000 people
- Sponsor
- Nycomed
ERAS, Colo-rectal Cancer
ERAS in Elderly Colorectal Cancer Surgery
Enhanced recovery protocol consisted of a series of elements aiming to optimize and standardize perioperative care. This study aims to evaluate the safety and feasibility of a modified ERAS protocol following colorectal surgery…
- Conditions
- ERAS, Colo-rectal Cancer, Elderly (people Aged 65 or More), Minimally Invasive Surgery
- Trial name
- STOMIS-ERAS (NCT06764888)
- Where
- Taiwan
- Volunteers
- 1,392 people
- Sponsor
- Chang Gung Memorial Hospital
Enhanced Recovery After Surgery, Infant ALL
A RCT Study of ERAS in Infants With Choledochal Cyst
Recently, with reference to the successful experience of accelerated rehabilitation surgery in the field of adult surgery, the investigators have conducted studies on ERAS in pediatric and even infant cholangiectasia surgery to…
- Conditions
- Enhanced Recovery After Surgery, Infant ALL, Cholangiectasis
- Trial name
- NCT05770739
- Testing
- Perioperative accelerated rehabilitation surgical measures, Traditional treatment
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Nanjing Children's Hospital
All Cause Mortality, MACE
ROOBY Trial Follow-up Extension
The Department of Veterans Affairs "Randomized On/Off Bypass" (ROOBY) Trial (CSP #517) was funded in 2001. ROOBY was designed to compare the short-term (30-day) and intermediate-term (1-year) outcomes for patients undergoing…
- Trial name
- NCT01924442
- Where
- United States
- Volunteers
- 2,203 people
- Sponsor
- VA Office of Research and Development
Myopia, Astigmatism
A Prospective Study of Femtosecond Laser Intracorneal Lensectomi
The purpose of this study is to compare visual acuity, safety, predictability, corneal biomechanics, dry eyes, and nerve-morphology after all femtosecond laser refractive lenticule extraction.
- Trial name
- NCT01673503
- Testing
- Carl Zeiss Meditech VisuMax laser
- Where
- Denmark
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Infections, Surgery
Study Looking at the Effect of Silverlon on Post Operative Wound Infections
This clinical study is a prospective, randomized, controlled trial of patients undergoing elective colorectal surgical procedures that receive an abdominal skin incision of at least 6 cm.
- Trial name
- NCT01143883
- Testing
- Silverlon, Standard of Care Dressing
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Jorge Marcet
Gallstones
Contrastive Study for Minimally Invasive Cholecystolithotomy With Gallbladder Reservation and Laparoscopic Cholecystectomy
To explore the therapeutic effects for treatment of cholecystolithiasis by minimally invasive cholecystolithotomy with gallbladder reservation and laparoscopic cholecystectomy.
- Trial name
- NCT01822262
- Testing
- minimally invasive cholecystolithotomy with gallbladder reservation, laparoscopic cholecystectomy
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chengyi Sun
All Minor Hand Surgery Including, Carpal Tunnel Syndrome
Nylon Versus Chromic Gut Sutures for Minor Hand Surgery
This study aims to assess the relationship between overall satisfaction with treatment in a group of randomized patients undergoing elective hand surgery using either absorbable (4-0 Chromic) or non-absorbable (5-0 Nylon)…
- Conditions
- All Minor Hand Surgery Including, Carpal Tunnel Syndrome, Trigger Finger, Ganglion Cysts
- Trial name
- NCT03407820
- Testing
- Absorbable Chromic gut sutures, Non-absorbable Nylon sutures
- Where
- 3 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Anesthesia, Local, Ophthalmopathy
Comparison Between Peribulbar And Sub-tenon Blocks on Oculocardiac Reflex (OCR) During Pediatric Strabismus Surgery
The aim of this study is to compare between peribulbar block and subtenon block as an adjunct to general anesthesia in children undergoing strabismus surgery on oculocardiac reflex (OCR), post-operative analgesia and…
- Conditions
- Anesthesia, Local, Ophthalmopathy, Strabismus, Pediatric ALL
- Trial name
- NCT06293586
- Testing
- peribulbar block, sub-tenon block, Paracetamol
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cairo University